Riccardo Gottardi, PhD

male silhouette icon
Riccardo Gottardi, PhD, is a research scientist with the Division of Pulmonary Medicine at Children's Hospital of Philadelphia.

Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Graduate Degree

PhD in Information and Communication Sciences and Technologies – Electronics and Information Engineering (Biomedical Electronics) - University of Genova, Genoa, Italy

MSc in Applied Physics - University of Pisa, Pisa, Italy

Titles and Academic Titles

Research Scientist

Departments and Services

Publications

Papers

2019

R. Di Gesù, G. Amato, R. Gottardi. Electrospun Scaffolds in Tendons Regeneration: a review. Muscles, Ligaments and Tendons Journal. 2019, 9(4): 478-493

B.B. Rothrauff, H. Sasaki, S. Kihara, K.J. Overholt, R. Gottardi, H. Lin, F.H. Fu, R.S. Tuan, P.G. Alexander. Point-of-Care Procedure for Enhancement of Meniscal Healing in a Goat Model Utilizing Infrapatellar Fat Pad-derived Stromal Vascular Fraction Cells in Photocrosslinkable Hydrogel. Am J Sports Med. 2019 Dec;47(14):3396-3405. doi: 10.1177/0363546519880468. Epub 2019 Oct 23.

R. Di Gesù, A. Acharya, I. Jacobs, R. Gottardi@ corresponding author. 3D Printing for Tissue Engineering in Otolaryngology. Connect Tissue Res. 2019 Sep 16:1-20. doi: 10.1080/03008207.2019.1663837. [Epub ahead of print]

N. Joseph, H.D. Lawson, K.J. Overholt, K. Damodaran, R. Gottardi, A.P. Acharya, S.R. Little. Synthesis and characterization of CaSr-Metal Organic Frameworks for biodegradable orthopedic applications. Scientific Reports. 2019, 9(1):13024.

R. Gottardi. Load-induced osteoarthritis on a chip. Nature Biomedical Engineering. 2019, 3:502-503, DOI: 10.1038/s41551-019-0427-y

T. Iseki, B.B. Rothrauff, S. Kihara, H. Sasaki, S. Yoshiya, F.H. Fu, R.S. Tuan, R. Gottardi@ corresponding author. Dynamic Compressive Loading Improves Cartilage Repair in an in vitro Model of Microfracture: Comparison of Two Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells. American Journal of Sports Medicine. 2019, 47(9):2188-2199. https://doi.org/10.1177/0363546519855645

2018

R. Gottardi, M. Stoddart. Regenerative rehabilitation of the musculoskeletal system. Journal of the American Academy of Orthopaedic Surgeons. 2018, 26(15): e321-e323, DOI: 10.5435/JAAOS-D-18-00220

H. Sasaki, B.B. Rothrauff, P.G. Alexander, H. Lin, R. Gottardi, F.H. Fu, R.S. Tuan. In vitro repair of meniscus radial tear using hydrogels seeded with adipose stem cells and TGF-β3. American Journal of Sports Medicine. 2018, 46(10): 2402-2413, doi: 10.1177/0363546518782973

P.N. Mittwede, R. Gottardi, P.G. Alexander, I.S. Tarkin, R.S. Tuan. Clinical Applications of Bone Tissue Engineering in Orthopaedic Trauma. Current Pathobiology Reports. 2018, 6(2): 99–108, DOI: 10.1007/s40139-018-0166-x.

L. Coluccino*, R. Gottardi* co-first author, F. Ayade, A. Athanassiou, R.S. Tuan, L. Ceseracciu. A Polyvinyl Alcohol Hydrogel Prosthetic Implant for Knee Meniscus Repair. ACS Biomaterials Science & Engineering. 2018, 4(5): 1518–1527, DOI: 10.1021/acsbiomaterials.7b00879

A. Pirosa, R. Gottardi, P.G. Alexander, R.S. Tuan. Engineering in vitro vascularized bone models for drug screening and predictive toxicology. Stem Cell Research & Therapy. 2018, 9: 112. DOI: 10.1186/s13287-018-0847-8

D.A. Nichols, I.S. Sondh, S.R. Little, P. Zunino, R. Gottardi@ corresponding author. Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis. Biomedical Microdevices. 2018, 20: 18. DOI: 10.1007/s10544-018-0264-x

2017

M.L. Ratay. E. Bellotti, R. Gottardi, S.R. Little. Modern Therapeutic Approaches for Ocular Diseases Involving Inflammation. Advanced Healthcare Materials. 2017, 6(2):1700733. DOI: 10.1002/adhm.201700733

E. Bayer, J. Jordan, A. Roy, R. Gottardi, M.V. Fedorchak, P. Kumta, S.R. Little. Programmed PDGF-BB and BMP-2 Delivery from a Hybrid, Calcium Phosphate/ Alginate Scaffold. Tissue Engineering. 2017, 23(23-24): 1382-1393. DOI: 10.1089/ten.TEA.2017.0027

B.B. Rothrauff, L. Coluccino, R. Gottardi, L. Ceseracciu, S. Scaglione, L. Goldoni, R.S. Tuan. Efficacy of thermoresponsive, photocrosslinkable hydrogels derived from decellularized tendon and cartilage extracellular matrix for cartilage tissue engineering. Journal of Tissue Engineering and Regenerative Medicine. 2017, 12(1):e159-e170. DOI: 10.1002/term.2465.

B.B. Rothrauff, K. Shimomura, R. Gottardi, P.G Alexander, R.S. Tuan. Anatomical region-specific enhancement of 3-dimensional chondrogenic differentiation of human mesenchymal stem cells by soluble meniscus extracellular matrix. Acta Biomaterialia. 2017, 49:140-151. DOI: 10.1016/j.actbio.2016.11.046

P.-o. Numpaisal, B.B. Rothrauff, R. Gottardi, C.-L. Chien, R.S. Tuan. Rapidly dissociated autologous meniscus tissue to enhance meniscus healing: an in vitro study. Connective Tissue Research. 2017, 58(3-4):355-365. DOI: 10.1080/03008207.2016.1245727

L. Coluccino, C. Peres, R. Gottardi, P. Bianchini, A. Athanassiou, A. Diaspro, L. Ceseracciu. Anisotropic Viscoelastic Biomechanical Mapping of Knee Meniscus Cartilage. Journal of Applied Biomaterials & Functional Materials. 2017, 15(1): e77-e83. DOI: 10.5301/jabfm.5000319

2016

R. Gottardi, U. Hansen, R. Raiteri, M. Loparic, M. Düggelin, D. Mathys, N.F. Friederich, P. Bruckner, and M. Stolz. Supramolecular organization of collagen fibrils in healthy and osteoarthritic human knee- and hip joint cartilage. PLoS ONE. 2016, 11(10): e0163552. DOI: 10.1371/journal.pone.0163552

L. Iannetti, G. D’Urso, G. Conoscenti, E. Cutrì, R.S. Tuan, M.T. Raimondi, R. Gottardi, P. Zunino. Distributed and lumped parameter models for the characterization of high throughput bioreactors. PLoS ONE. 2016, 11(9): e0162774. DOI: 10.1371/journal.pone.0162774

A.X. Sun, P.-o. Numpaisal, R. Gottardi, H. Shen, G. Yang, R.S. Tuan. Cell and Biomimetic Scaffold Based Approaches for Cartilage Regeneration. Operative Techniques in Orthopaedics. 2016, 26(3): 135–146. DOI: 10.1053/j.oto.2016.06.003

Jr-Jiun J. Liou, M.T. Langhans, R. Gottardi, R.S. Tuan. Injury and Repair of Tendon, Ligament and Meniscus. Chapter 6 in: Translating Regenerative Medicine to the Clinic edited by J. Laurence, P. Baptista, A. Atala and M. Van Beusekom. Academic Press, Elsevier, 2016: 75-88.

2015

R. Gottardi. Towards a minimally invasive sampling tool for high resolution tissue analytical mapping. Nanotechnology. 2015, 26, 372501-4. DOI: 10.1088/0957-4484/26/37/372501

M. Guaragno, R. Gottardi, M.V. Fedorchak, A. Roy, P. Kumta, S.R. Little. One-Step Synthesis of Fluorescently Labeled Single-Walled Carbon Nanotubes. Chemical Communications. 2015, 51, 17233-17236. DOI: 10.1039/c5cc05573c

E. Bayer, R. Gottardi, M.V. Fedorchak, S.R. Little. The Scope and Sequence of Growth Factor Delivery for Vascularized Bone Tissue Regeneration. Journal of Controlled Release. 2015, 219: 129-140. DOI: 10.1016/j.jconrel.2015.08.004  

M. Taffetani, R. Raiteri, R. Gottardi, D. Gastaldi, P. Vena. A quantitative interpretation of atomic force microscopy based dynamic nanoindentation tests on articular cartilage. Journal of Biomechanical Engineering. 2015, 137(7), 071005-1:8. DOI: 10.1115/1.4030175

A.J. Glowacki, R. Gottardi, S. Yoshizawa, F. Cavalla, G.P. Garlet, C. Sfeir, S.R. Little. Strategies to direct the enrichment, expansion, and recruitment of regulatory cells for the treatment of disease. Annals of Biomedical Engineering. 2015, 43(3): 593-602. DOI: 10.1007/s10439-014-1125-2

2014

A. D'Amore, N. Amoroso, R. Gottardi, C. Hobson, C. Carruthers, S. Watkins, W. Wagner, M. Sacks. From single fiber to macro-level mechanics: A structural finite-element model for elastomeric fibrous biomaterials. Journal of the Mechanical Behavior of Biomedical Materials. 2014, 39: 146-161. DOI: 10.1016/j.jmbbm.2014.07.016

M. Taffetani, R. Gottardi, D. Gastaldi, R. Raiteri, P. Vena. Poroelastic response of articular cartilage by nanoindentation creep tests with different characteristic sizes. Medical Engineering & Physics. 2014, 36(7): 850-858. DOI: 10.1016/j.medengphy.2014.03.008

H. Lin, T.P. Lozito, P.G. Alexander, R. Gottardi, R.S. Tuan. Stem Cell-based Microphysiological Osteochondral System to Model Tissue Response to Interleukin-1β. Molecular Pharmaceutics. 2014, 11(7): 2203-12. DOI: 10.1021/mp500136b

P.G. Alexander*, R. Gottardi* co-first author, H. Lin, T.P. Lozito, R.S. Tuan. Three Dimensional Osteogenic and Chondrogenic Systems to Model Osteochondral Physiology and Degenerative Joint Diseases. Experimental Biology and Medicine. 2014, 239: 1080-1095. DOI: 10.1177/1535370214539232

2013

K. Kamalasanan*, R. Gottardi* co-first author, S. Tan, Y. Chen, B. Godugu, S. Rothstein, A.C. Balazs, A. Star, S.R. Little. “Zero Dimensional” Single Walled Carbon Nanotubes. Angewandte Chemie. 2013, 52(43): 11308-11312. DOI: 10.1002/anie.201305526

T.P. Lozito, P.G. Alexander, H. Lin, R. Gottardi, A.W.-M. Cheng, R.S. Tuan. Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis. Stem Cell Research & Therapy. 2013, 4(Suppl 1):S6. DOI: 10.1186/scrt367

G. Yang, B.B. Rothrauff, H. Lin, R. Gottardi, P.G. Alexander, R.S. Tuan. Enhancement of Tenogenic Differentiation of Human Adipose Stem Cells by Tendon-Derived Extracellular Matrix. Biomaterials. 2013, 34(37): 9295-306. DOI: 10.1016/j.biomaterials.2013.08.054

R. Gottardi*, B. Douradinha*. Carbon nanotubes as a novel tool for vaccination against infectious diseases and cancer. Journal of Nanobiotechnology. 2013, 11:30 *equal contribution. DOI: 10.1186/1477-3155-11-30

W.R. Thompson, R. Gottardi, K.M. Stearns, J. Rubin, F. Ambrosio, R.S. Tuan. Biologics in Cartilage, Bone Repair, and Regeneration. In: Hughes C, ed. ISC 23.2, Applications of Regenerative Medicine to Orthopaedic Physical Therapy. La Crosse, WI: Orthopaedic Section APTA; 2013.

2012

M. Taffetani, E. Bertarelli, R. Gottardi, R. Raiteri, and P. Vena. Modeling of the Frequency Response to Dynamic Nanoindentation of Soft Hydrated Anisotropic Materials: Application to Articular Cartilage. Computer Modeling in Engineering & Science. 2012, 87, 5 433-460.

2009

M. Stolz, R. Gottardi, R. Raiteri, S. Miot, I. Martin, R. Imer, U. Staufer, A. Raducanu, M. Düggelin, W. Baschong, A.U. Daniels, N. F. Friederich, A. Aszodi, U. Aebi. Early detection of osteoarthritic and aging articular cartilage in mice and patient samples using AFM. Nature Nanotechnology. 2009, 4:186-192. DOI: 10.1038/nnano.2008.410

2006

A. Marsano, D. Wendt, R. Raiteri, R. Gottardi, M. Stolz, D. Wirz, A.U. Daniels, D. Salter, M. Jakob, T.M. Quinn, I. Martin. Use of hydrodynamic forces to engineer cartilaginous tissues resembling the non-uniform structure and function of meniscus. Biomaterials. 2006, 27: 5927-5934. DOI: 10.1016/j.biomaterials.2006.08.020

2004

C. Ascoli, R. Gottardi, D. Petracchi, 2004. Scanning probe microscopy. In: Lasers and current optical techniques in biology, edited by Giuseppe Palumbo and Riccardo Pratesi, London: The Royal Chemical Society, 2004: 375-427

Posters and Presentations

2019

T. Iseki, B.B. Rothrauff, S. Kihara, S. Yoshiya, F.H. Fu, R.S. Tuan, R. Gottardi. Early Weight-Bearing Improves Cartilage Repair in an in vitro Model of Microfracture:Comparison of Two Mechanical Loading Regimens on Simulated Microfracture Based onFibrin Gel Scaffolds Encapsulating Bone Marrow Mesenchymal Stem Cells. American Orthopaedic Society for Sports Medicine, AOSSM Annual Meeting, Boston MA, 2019

R. Gottardi, A. Pirosa, P. Alexander, P. Manner, D. Puppi, F. Chiellini, R.S. Tuan. An in vitro Chondro-Osteo-Vascular Triphasic Model Of The Osteochondral Complex. Society for Biomaterials, Seattle, WA, April 2019.

R. Gottardi, E. Capuana, D. Marino, V. La Carrubba, V. Brucato, R.S. Tuan. HiT-MACE: A High-Throughput Mechanical Activator for Cartilage Engineering to Study the Early Cartilage Response to Physiological and Supra-Physiological Loads. Orthopaedic Research Society Annual Meeting, Austin, TX, February 2019.

2018

R. Gottardi, G. Conoscenti, P.G. Alexander, V. La Carrubba, V. Brucato, R.S. Tuan. A Poly-L-Lactide Scaffold with Continuous Gradient Pore Size That Differentially Induce Local Chondrogenesis and Osteogenesis for Osteochondral Repair. American Institute of Chemical Engineers Annual Meeting, Pittsburgh, PA, October 2018.

R. Gottardi, G. De Riccardis, M. Avolio, D.A. Nichols, A. Pirosa, P.G. Alexander, M.T. Raimondi, R.S. Tuan. A 3D Printed Microfluidic Bioreactor to Engineer Biphasic Construct. American Institute of Chemical Engineers Annual Meeting, Pittsburgh, PA, October 2018.

R. Gottardi, A. Pirosa, P.G. Alexander, D. Puppi, F. Chiellini, R.S. Tuan. An in Vitro Chondro-Osteo-Vascular Triphasic Model of the Osteochondral Complex. American Institute of Chemical Engineers Annual Meeting, Pittsburgh, PA, October 2018.

T. Iseki, H. Sasaki, S. Kihara, S. Yoshiya, F.H. Fu, R.S. Tuan, R. Gottardi. Early Weight Bearing Improves Cartilage Repair in an Engineered In Vitro Model of Microfracture. Biomedical Engineering Society Annual Meeting, Atlanta, GA, October 2018.

R. Gottardi, V. Rotolo, A. Khalajzadeh, A. Roy, P. Kumta, M.T. Raimondi, P.G. Alexander, R.S. Tuan. Creation of a 3D Bone Tissue Model to Study Bone Loss in Microgravity. Biomedical Engineering Society Annual Meeting, Atlanta, GA, October 2018.

R. Gottardi, G. Conoscenti, P.G. Alexander, V. La Carrubba, V. Brucato, R.S. Tuan. A PLLA Scaffold with a Biomimetic Continuous Gradient Pore Size that Differentially Induces Local Chondrogenesis and Osteogenesis for Osteochondral Repair. Biomedical Engineering Society Annual Meeting, Atlanta, GA, October 2018.

R. Gottardi, G. De Riccardis, M. Avolio, D.A. Nichols, I. Sondh, A. Pirosa, P.G. Alexander, M.T. Raimondi, R.S. Tuan. A 3D Printed Microfluidic Bioreactor to Engineering Biphasic Musculoskeletal Construct. Biomedical Engineering Society Annual Meeting, Atlanta, GA, October 2018.

K.J. Overholt, R.S. Tuan, R. Gottardi. An IL-1β Mediated Model of Osteochondral Tissue Catabolism. Biomedical Engineering Society Annual Meeting, Atlanta, GA, October 2018.

C. Snodgrass, V. Garofalo, A. Khalajzadeh, P.G. Alexander, R.S. Tuan, R. Gottardi. Development of a 3D Biphasic Osteochondral Model for In Vitro Osteoporosis Drug Discovery. Biomedical Engineering Society Annual Meeting, Atlanta, GA, October 2018.

R. Gottardi, G. De Riccardis, M. Avolio, D.A. Nichols, P.G. Alexander, P. Zunino, M.T. Raimondi, R.S. Tuan. A 3D Printed Microfluidic Bioreactor to Engineering Biphasic Musculoskeletal Construct. Tissue Engineering and Regenerative Medicine International Society – World Annual Meeting, Kyoto, Japan, September 2018.

R. Gottardi, S. Kihara, T. Iseki, F.H. Fu, R.S. Tuan. Effect of ACL and PCL derived soluble ECM for tenogenic differentiation of adipose derived stem cell. Tissue Engineering and Regenerative Medicine International Society – World Annual Meeting, Kyoto, Japan, September 2018.

R. Gottardi, S. Kelley, V. Rotolo, A. Roy, P.N. Kumta, M.T. Raimondi, P.G. Alexander, R.S. Tuan Creation of a 3D Bone Tissue Model to Study Bone Loss in Microgravity. Tissue Engineering and Regenerative Medicine International Society – World Annual Meeting, Kyoto, Japan, September 2018.

T. Iseki, R. Gottardi, S. Yoshiya, F.H. Fu, R.S. Tuan. Early Weight-Bearing Improves Cartilage Repair in an In Vitro Model of Microfracture: Comparison with Two Mechanical Loading on Fibrin Gel Scaffolds Containing Bone Marrow Mesenchymal Stem Cells. Tissue Engineering and Regenerative Medicine International Society – World Annual Meeting, Kyoto, Japan, September 2018.

T. Iseki, H. Sasaki, S. Kihara, A. Frank, M. Bottlang, S. Yoshiya, F.H. Fu, R.S. Tuan, R. Gottardi. Early Weight-Bearing Improves Cartilage Repair in an In Vitro Model of Microfracture. Gordon Research Conference, – Musculoskeletal Biology and Engineering. Andover, NH, August 2018.

R. Gottardi, G. Conoscenti, P.G. Alexander, V. La Carrubba, V. Brucato, R.S. Tuan. A Continuous Pore Size Gradient PLLA Scaffold for Osteochondral Regeneration Tested in a Biphasic Bioreactor. Society for Biomaterials, Atlanta, GA, April 2018.

R. Gottardi, V. Rotolo, A. Roy, P.N. Kumta, M.T. Raimondi, P.G. Alexander, R.S. Tuan. Creation of a 3D Bone Tissue Model to Study Bone Loss in Microgravity. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 2018.

R. Gottardi, G. De Riccardis, D.A. Nichols, I.S. Sondh, A. Pirosa, P.G. Alexander, M.T. Raimondi, R.S. Tuan. A 3D Printed Microfluidic Bioreactor to Engineering Biphasic Musculoskeletal Construct. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 2018.

T. Iseki, H. Sasaki, S. Kihara, A. Frank, M. Bottlang, S. Yoshiya, F.H. Fu, R.S. Tuan, R. Gottardi. Early Weight-Bearing Improves Cartilage Repair in an In Vitro Model of Microfracture. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 2018.

S. Kihara, R. Gottardi, T. Iseki, F.H. Fu, R.S. Tuan. Effect of Soluble ECM Derived From ACL and PCL on Tenogenic Differentiation of Adipose Derived Stem Cells. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 2018.

2017

T. Iseki, S. Kihara, H. Sasaki, S. Yoshiya, F. Fu, R.S. Tuan, R. Gottardi. Engineered In Vitro Models for the Guidance of Rehabilitation Regimens that Promote Cartilage Regeneration after Repair Surgery. Tissue Engineering and Regenerative Medicine International Society – Americas Annual Meeting, Charlotte, NC, December 2017.

G. De Riccardis, P.G. Alexander, M.T. Raimondi, R.S. Tuan, R. Gottardi. A 3D Printed Microfluidic Bioreactor to Engineering Biphasic Construct. Tissue Engineering and Regenerative Medicine International Society – Americas Annual Meeting, Charlotte, NC, December 2017.

T. Iseki, S. Kihara, H. Sasaki, S. Yoshiya, F. Fu, R.S. Tuan, R. Gottardi. In vitro models for the guidance of rehabilitation regimens that promote cartilage regeneration after repair surgery. Biomedical Engineering Society Annual Meeting, Phoenix, AZ, October 2017.

G. De Riccardis, P.G. Alexander, M.T. Raimondi, R.S. Tuan, R. Gottardi. A 3D Printed Microfluidic Bioreactor to Engineering Biphasic Construct: Modelling and Experimental Validation. Biomedical Engineering Society Annual Meeting, Phoenix, AZ, October 2017.

A. Pirosa, R. Gottardi, P.G. Alexander, D. Puppi, F. Chiellini, R.S. Tuan. An In Vitro Chondro-Osteo-Vascular Triphasic Model of the Osteochondral Complex. Biomedical Engineering Society Annual Meeting, Phoenix, AZ, October 2017.

K. Overholt, A. Pirosa, R.S. Tuan, R. Gottardi. Validation of an Osteochondral Bioreactor for In Vitro Drug Screening. Biomedical Engineering Society Annual Meeting, Phoenix, AZ, October 2017.

R. Gottardi, P.G. Alexander, P. Simson, V. Rotolo, C. Britt, J.P. Wikswo, R.S. Tuan. A Microphysiological 3D Organotypic Culture System for Studying Degradation and Repair of Composite Skeletal Tissues in Microgravity. International Space Station Research&Development Conference 2017, Washington DC, July 2017.

R. Gottardi, H. Lin, L. Iannetti, G. D’Urso, P. Zunino, T.P. Lozito, P.G. Alexander, P. Manner, R.S. Tuan. Validation of an osteochondral bioreactor applied to study the protective role of sex hormones. Tissue Engineering and Regenerative Medicine International Society – EU Annual Meeting, Davos, Switzerland, June 2017.

R. Gottardi, A. Pirosa, P.G. Alexander, D. Puppi, F. Chiellini, R.S. Tuan. An in vitro chondro-osteo-vascular triphasic model of the osteochondral complex. Tissue Engineering and Regenerative Medicine International Society – EU Annual Meeting, Davos, Switzerland, June 2017.

R. Gottardi, G. Conoscenti, P.G. Alexander, V. La Carrubba, V. Brucato, R.S. Tuan. A continuous pore size gradient PLLA scaffold for osteochondral regeneration. Tissue Engineering and Regenerative Medicine International Society – EU Annual Meeting, Davos, Switzerland, June 2017.

T. Iseki, R. Gottardi, H. Sasaki, S. Kihara, S. Yoshiya, F. Fu, R.S. Tuan. The Response of Bone Marrow Mesenchymal Stem Cells with Fibrin Gel Scaffolds Mimicking Microfracture to Mechanical Stress. 9th annual meeting of the Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine (JOSKAS), Sapporo, Japan, June 2017.

H. Sasaki, B.B. Rothrauff, P.G. Alexander, R. Gottardi, H. Lin, F.H. Fu, R.S. Tuan. In Vitro Repair Of Meniscus Radial Tear Using Hydrogels Seeded With Adipose-Derived Stem Cells And TGF-ß3. 11th Biennial International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine Congress, Shanghai, China, June 2017.

L. Iannetti, G. D’Urso, G. Conoscenti, E. Cutrì, R.S. Tuan, M.T. Raimondi, R. Gottardi, P. Zunino. Distributed And Lumped Parameter Models For The Characterization Of High Throughput Bioreactors. 5th International Conference on Computational and Mathematical Biomedical Engineering – CMBE2017, Pittsburgh, PA, April 2017.

R. Gottardi, G. D'Urso, L. Iannetti, G. Conoscenti, E. Cutrì, M.T. Raimondi, P. Zunino, R.S. Tuan. Dual Fluidic High Throughput Bioreactor Obtained by 3D Printing, for Osteochondral and Other Biphasic Tissue Constructs Targeted at High Throughput Screening: Computational Model and Experimental Validation. Orthopaedic Research Society Annual Meeting, San Diego, CA, March 2017.

H. Sasaki, B.B. Rothrauff, P.G. Alexander, H. Lin, R. Gottardi, F. Fu, R.S. Tuan. In Vitro Repair of Meniscus Radial Tear Using Hydrogels Seeded with Adipose-derived Stem Cells and TGF-β3. Orthopaedic Research Society Annual Meeting, San Diego, CA, March 2017.

R. Gottardi, A. Pirosa, G. Conoscenti, H. Lin, G. D’Urso, L. Iannetti, P. Zunino, T.P. Lozito, P.G. Alexander, V. La Carrubba, V. Brucato, R.S. Tuan. An Osteochondral Microphysiological System To Study Cartilage-Bone Interaction In Native Tissues And Engineered Model Constructs. Fusion Conference on Musculoskeletal Development and Regeneration, Cancun, Mexico, February 2017.

Invited Lectures

2019

Gottardi R. Invited talk: Mechanical and microtopological environment to drive chondrogenesis. Tissue Engineering and Regenerative Medicine International Society – EU Annual Meeting, May 2019, Rhodes, Greece (Dr. Dimitrios Zeugolis).

2018

Gottardi R. Workshop: A 3D Organotypic Culture System to Study Composite Skeletal Tissues Physiology in Microgravity. CASIS/University of Pittsburgh: Exploring Partnership Opportunities (Amy Phillips, Director of Partnerships, Office of Economic Partnerships, University of Pittsburgh). October 16, 2018

Gottardi R. Invited talk: Loads, structure and signaling for cartilage regeneration. First Ri.MED Research Retreat, Palermo, Italy (Dr. Alessandro Padova). October 11, 2018.

Gottardi R. Invited talk: 3D osteochondral microphysiological systems: from cartilage-bone crosstalk, to screening regenerative approaches, to space research. European Orthopaedic Research Society Annual Meeting, September 2018, Galway, Ireland (Dr. Dimitrios Zeugolis).

Gottardi R. Seminar: Regenerative Rehabilitation and Biomimetic Topology to Direct Osteochondral Repair. Institute for Stem Cell & Regenerative Medicine, University of Washington, Seattle, WA (Dr. Charles E. Murry). May 4, 2018.

Gottardi R. Seminar: Loads, structure and signaling for cartilage regeneration. Department of Bioengineering, Temple University, Philadelphia, PA (Dr. Peter Lelkes). March 21, 2018

Gottardi R. Seminar: Loads, structure and signaling for cartilage regeneration. Division of Otolaryngology, Children’s Hospital of Philadelphia, PA (Dr. Ian Jacobs, MD). March 20, 2018

2017

Gottardi R. Seminar: Loads, structure and signaling in models of joint regeneration. Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico, Rome, Italy (Dr. Gianluca Vadalà, MD). December 5, 2017.

Gottardi R. Keynote speaker: Workshop on Nanoengineering for Mechanobiology. Camogli, Italy (Dr. Aldo Ferrari, ETH Zurich, Dr. Massimo Vassalli, CNR Genova, Dr. Manuela Teresa Raimondi, Politecnico di Milano). March 26-29, 2017.

Awards and Honors

2019, Outstanding Abstract Award – Society for Biomaterials 2019 Annual Meeting
2018, Travel Award to attend AAOS/ORS The Physis
2017, Young Investigator Award at the 2nd Fusion Conference on Musculoskeletal Development and Regeneration Conference
2016, Iris Klarman Women’s Health Fellowship Award from the Foundation for Women’s Wellness
2016, Pitt Innovator Award
2015, Bridgeside Research Forum - Best Presentation Award
2015, First prize at the Penn Orthopaedics 2015 Cartilage Repair Symposium
2014, Travel Award to attend AAOS/CORR/ORS/CMH-UCD/SWHR
2014, Travel Award for Best Poster at the annual University of Pittsburgh Postdoctoral Association Symposium
2014, Scholarship for the course “From Benchtop to Bedside: what every scientist needs to know
2011-2016, Ri.MED Foundation postdoctoral fellowship
2010, Travel fellowship for the Annual Meeting of the International Cartilage Repair Society 2010, Sitges, Spain
2006, First prize at the Ninth International Summer School on Biophysics “Supramolecular Structure and Function”, Rovinj, Croatia
2006, Scholarship for the Ninth International Summer School on Biophysics “Supramolecular Structure and Function”, Rovinj, Croatia
2004-2006, “Young Researcher” PhD scholarship (ex DM198/2003) Italian Ministry of Education, University and Research
1999, Socrates/Erasmus scholarship

Editorial and Academic Positions

Editorial Positions

Ad Hoc Reviewer

Nature Biomedical Engineering
Science Advances
Biomaterials
Acta Biomaterialia
Lab on a Chip
Scientific Reports
Biomacromolecules
Tissue Engineering and Regenerative Medicine
European Journal of Pharmaceutics and Biopharmaceutics
Biotechnology and Bioengineering
Tissue Engineering
Nanotechnology
Clinical Oral Implants Research
Materials Science & Engineering, part C
Biomedical Materials
Developmental Biology
Stem Cell Research and Therapy
Biointerphases
Plos One
Journal of Materials Science: Materials in Medicine
Organogenesis
Materials Letters
Polymer Composites
Clinical Biomechanics
ASME Journal of Biomechanical Engineering
Medical Engineering & Physics
Connective Tissue Research
Journal of Bioanalysis & Biomedicine
BMC Research Notes
Diabetes/Metabolism Research and Reviews
Biomedicine and Pharmacotherapy

Leadership and Memberships

Memberships in Professional Organizations

2018-present, Society for Biomaterials
2016-present, Orthopaedic Research Society
2013-present, Tissue Engineering and Regenerative Medicine International Society
2012-present, Biomedical Engineering Society
2012-present, American Institute of Chemical Engineering
2010-present, International Cartilage Repair Society