Frederick D. Grant, MD
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MD - State University of New York (SUNY) Upstate Medical University, Syracuse, NY
Internal Medicine - University of Pittsburgh Medical Center, Pittsburgh, PA
Internal Medicine - University of Pittsburgh Medical Center, Pittsburgh, PA
Research Fellow, Physician Investigator Training Program - University of Pittsburgh School of Medicine, Pittsburgh, PA
Clinical and Research Fellow, Endocrinology and Hypertension - Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Nuclear Medicine - Brigham and Women's Hospital, Harvard Medical School, Boston, MA (Chief Resident)
Diagnostic Radiology - Mount Auburn Hospital, Harvard Medical School, Cambridge, MA
Pediatric Radiology - Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA
Diagnostic Radiology – American Board of RadiologyEndocrinology, Diabetes and Metabolism – American Board of Internal MedicineInternal Medicine – American Board of Internal MedicineNuclear Medicine – American Board of Nuclear Medicine
Partington SL, Valente AM, Bruyere J Jr, Rosica D, Shafer KM, Landzberg MJ, Taqueti VR, Blankstein R, Skali H, Kwatra N, DiCarli MF, Grant FD, Dorbala S.: Reducing radiation dose from myocardial perfusion imaging in subjects with complex congenital heart disease. Journal of Nuclear Cardiology: official publication of the American Society of Nuclear Cardiology 28(4): 1395-1408, Aug 2021 Notes: Dr. Grant was the lead pediatric nuclear medicine collaborator/co-author; DOI: 10.1007/s12350-019-01811-y. PMCID: PMC7104915
Kwatra, N. S., Nurko, S., Stamoulis, C., Falone, A. E., Grant, F. D., & Treves, S. T.: Chronic Acalculous Cholecystitis in Children With Biliary Symptoms: Usefulness of Hepatocholescintigraphy. Journal of Pediatric Gastroenterology and Nutrition 68(1): 68-73, Jan 2019 Notes: This is a peer-reviewed research publication; DOI: 10.1097/MPG.0000000000002151.
Ozuah NW, Dahmoush HM, Grant FD, Lehmann LE, LaCasce AS, Billett AL, Margossian SP: Pretransplant functional imaging and outcome in pediatric patients with relapsed/refractory Hodgkin lymphoma undergoing autologous transplantation. Pediatric Blood & Cancer 65(1), Jan 2018 Notes: This is a peer-reviewed research publication; DOI: 10.1002/pbc.26707; Dr. Grant was the senior nuclear medicine collaborator and co-author.
Komarraju A, Bartel TB, Dickinson LA, Grant FD, Yarbrough TL: Implementation of a Flipped Classroom for Nuclear Medicine Physician CME. The Journal of Continuing Education in the Health Professions 38(3): 198-204, Summer 2018 Notes: DOI: 10.1097/CEH.0000000000000204.
Maclellan RA, Zurakowski D, Grant FD, Greene AK: Massive Localized Lymphedema: A Case-Control Study. Journal of the American College of Surgeons 224(2): 212-216, Feb 2017 Notes: Peer reviewed research publication; DOI: 10.1016/j.jamcollsurg.2016.10.047; Dr. Grant was the only collaborator/co-author from Radiology or Nuclear Medicine.
Hassanein AH, Maclellan RA, Grant FD, Greene AK.: Diagnostic Accuracy of Lymphoscintigraphy for Lymphedema and Analysis of False-Negative Tests. Plastic and Reconstructive Surgery 5(7): e1396, Jul 2017 Notes: Dr. Grant was the only collaborator/co-author from Radiology/Nuclear Medicine; DOI: 10.1097/GOX.0000000000001396. PMCID: PMC5548565
Gauguet JM, Pace-Emerson T, Grant FD, Shusterman S, DuBois SG, Frazier AL, Voss SD.: Evaluation of the utility of (99m) Tc-MDP bone scintigraphy versus MIBG scintigraphy and cross-sectional imaging for staging patients with neuroblastoma. Pediatric Blood Cancer 64(11): 26601, Nov 2017 Notes: This is a peer-reviewed research publication; DOI: 10.1002/pbc.26601.
Ly S, Frates MC, Benson CB, Peters HE, Grant FD, Drubach LA, Voss SD, Feldman HA, Smith JR, Barletta J, Hollowell M, Cibas ES, Moore FD Jr, Modi B, Shamberger RC, Huang SA.: Features and Outcome of Autonomous Thyroid Nodules in Children: 31 Consecutive Patients Seen at a Single Center. The Journal of Clinical Endocrinology and Metabolism 101(10): 3856-3862, Oct 2016 Notes: Dr. Grant was the lead collaborator and co-author from pediatric nuclear medicine; DOI: 10.1210/jc.2016-1779. PMCID: PMC5052348
Cao, X., Xu, X., Grant, F. D., & Treves, S. T.: Estimation of Split Renal Function With 99mTc-DMSA SPECT: Comparison Between 3D Volumetric Assessment and 2D Coronal Projection Imaging. AJR. American Journal of Roentgenology 207(6): 1324-1328, Dec 2016 Notes: DOI: 10.2214/AJR.16.16307. PMCID: PMC5559895
Grant FD, Gelfand MJ, Drubach LA, Treves ST, Fahey FH.: Radiation doses for pediatric nuclear medicine studies: comparing the North American consensus guidelines and the pediatric dosage card of the European Association of Nuclear Medicine. Pediatric Radiology 45(5): 706-713, Apr 2015 Notes: This is a research peer-reviewed research publication; DOI: 10.1007/s00247-014-3211-x.
Greene AK, Grant FD, Slavin SA, Maclellan RA.: Obesity-induced lymphedema: clinical and lymphoscintigraphic features. Plastic and Reconstructive Surgery 135(6): 1715-1719, Jun 2015 Notes: This is a peer-reviewed comparative study (research publication); DOI: 10.1097/PRS.0000000000001271; Dr. Grant was the only collaborator and co-author from radiology or nuclear medicine.
Maclellan RA, Couto RA, Sullivan JE, Grant FD, Slavin SA, Greene AK.: Management of Primary and Secondary Lymphedema: Analysis of 225 Referrals to a Center. Annals of Plastic Surgery 75(2): 197-200, Aug 2015 Notes: This is a peer-reviewed research publication; DOI: 10.1097/SAP.0000000000000022; Dr. Grant was the only collaborator and co-author from radiology or nuclear medicine.
Fahey F, Zukotynski K, Zurakowski D, Markelewicz R, Falone A, Vitello M, Cao X, Grant F, Drubach L, Vija AH, Bhattacharya M, Ding X, Bar-Sever Z, Gelfand M, Treves ST: Beyond current guidelines: reduction in minimum administered radiopharmaceutical activity with preserved diagnostic image quality in pediatric hepatobiliary scintigraphy. European Journal of Nuclear Medicine and Molecular Imaging 41(12): 2346-53, Dec 2014 Notes: DOI: 10.1007/s00259-014-2860-1.
Spencer, H. T., Sokol, L. O., Glotzbecker, M. P., Grant, F. D., d'Hemecourt, P. A., Micheli, L. J., & Treves, S. T. : Detection of pars injury by SPECT in patients younger than age 10 with low back pain. Journal of Pediatric Orthopedics 33(4): 383-8, Jun 2013 Notes: DOI: 10.1097/BPO.0b013e318285c3be.
Markelewicz RJ Jr, Lorenzen WA, Shusterman S, Grant FD, Fahey FH, Treves ST: Radiation exposure to family caregivers and nurses of pediatric neuroblastoma patients receiving 131I-metaiodobenzylguanidine (131I-MIBG) therapy. Clinical Nuclear Medicine 38(8): 604-7, Aug 2013 Notes: DOI: 10.1097/RLU.0b013e31829af3c8.
Routh, J. C., Grant, F. D., Kokorowski, P. J., Nelson, C. P., Fahey, F. H., Treves, S. T., & Lee, R. S.: Economic and radiation costs of initial imaging approaches after a child's first febrile urinary tract infection. Clinical Pediatrics 51(1): 23-30, Jan 2012 Notes: Dr. Grant was the lead collaborator and co-author from nuclear medicine/radiology; DOI: 10.1177/0009922811417294. PMCID: PMC3792796
Schook CC, Mulliken JB, Fishman SJ, Grant FD, Zurakowski D, Greene AK.: Primary lymphedema: clinical features and management in 138 pediatric patients. Plastic and Reconstructive Surgery 127(6): 2419-2431, Jun 2011 Notes: Dr. Grant was the only collaborator and co-author from nuclear medicine/radiology; DOI: 10.1097/PRS.0b013e318213a218.
Hsiao EM, Cao X, Zurakowski D, Zukotynski KA, Drubach LA, Grant FD, Yahil A, Vija AH, Davis RT, Fahey FH, Treves ST.: Reduction in radiation dose in mercaptoacetyltriglycerine renography with enhanced planar processing. Radiology 261(3): 907-15, Dec 2011 Notes: DOI: 10.1148/radiol.11110602.
Zukotynski K, Curtis C, Grant FD, Micheli L, Treves ST.: The value of SPECT in the detection of stress injury to the pars interarticularis in patients with low back pain. Journal of Orthopaedic Surgery and Research 5: 13, Mar 2010 Notes: DOI: 10.1186/1749-799X-5-13. PMCID: PMC2841113
Drubach LA, Johnston PR, Newton AW, Perez-Rossello JM, Grant FD, Kleinman PK.: Skeletal trauma in child abuse: detection with 18F-NaF PET. Radiology 255(1): 173-81, Apr 2010 Notes: DOI: 10.1148/radiol.09091368.
Zukotynski KA, Fahey FH, Laffin S, Davis R, Treves ST, Grant FD, Drubach LA.: Seasonal variation in the effect of constant ambient temperature of 24 degrees C in reducing FDG uptake by brown adipose tissue in children. European Journal of Nuclear Medicine and Molecular Imaging 37(10): 1854-60, Oct 2010 Notes: DOI: 10.1007/s00259-010-1485-2.
Routh JC, Grant FD, Kokorowski P, Lee RS, Fahey FH, Treves ST, Nelson CP.: Costs and consequences of universal sibling screening for vesicoureteral reflux: decision analysis. Pediatrics 126(5): 865-871, Nov 2010 Notes: Dr. Grant was the lead collaborator and co-author from nuclear medicine/radiology; DOI: 10.1542/peds.2010-0744. PMCID: PMC3098562
Zukotynski, K. A., Fahey, F. H., Laffin, S., Davis, R., Treves, S. T., Grant, F. D., & Drubach, L. A.: Constant ambient temperature of 24 degrees C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter. European Journal of Nuclear Medicine and Molecular Imaging 36(4): 602-6, Apr 2009 Notes: DOI: 10.1007/s00259-008-0983-y.
Chirnomas, D., Smith, A. L., Braunstein, J., Finkelstein, Y., Pereira, L., Bergmann, A. K., Grant, F. D., Paley, C., Shannon, M., & Neufeld, E. J.: Deferasirox pharmacokinetics in patients with adequate versus inadequate response. Blood 114(19): 4009-13, Nov 2009 Notes: Dr. Grant was the only collaborator and co-author from nuclear medicine/radiology; DOI: 10.1182/blood-2009-05-222729. PMCID: PMC2774541
Mitchell JC, Grant F, Evenson AR, Parker JA, Hasselgren PO, Parangi S.: Preoperative evaluation of thyroid nodules with 18FDG-PET/CT. Surgery 138(6): 1166-74, Dec 2005 Notes: DOI: 10.1016/j.surg.2005.08.031.
Grant FD, Romero JR, Jeunemaitre X, Hunt SC, Hopkins PN, Hollenberg NH, Williams GH.: Low-renin hypertension, altered sodium homeostasis, and an alpha-adducin polymorphism. Hypertension 39(2): 191-6, Feb 2002 Notes: DOI: 10.1161/hy0202.104273.
Kenney LB, Laufer MR, Grant FD, Grier H, Diller L: High risk of infertility and long term gonadal damage in males treated with high dose cyclophosphamide for sarcoma during childhood. Cancer 91(3): 613-21, Feb 2001 Notes: Dr. Grant was the only endocrinology collaborator and co-author; DOI: 10.1002/1097-0142(20010201).
Song S, Wang Y, Bak SY, During MJ, Bryan J, Ashe O, Ullrey DB, Trask LE, Grant FD, O'Malley KL, Riedel H, Goldstein DS, Neve KA, LaHoste GJ, Marshall JF, Haycock JW, Neve RL, Geller AI.: Modulation of rat rotational behavior by direct gene transfer of constitutively active protein kinase C into nigrostriatal neurons. The Journal of Neuroscience: the official journal of the Society for Neuroscience 18(11): 4119-32, Jun 1998 Notes: DOI: 10.1523/JNEUROSCI.18-11-04119.1998. PMCID: PMC6792804
Grant FD, Ahmadi A, Hosley CM, Majzoub JA.: Two novel mutations of the vasopressin gene associated with familial diabetes insipidus and identification of an asymptomatic carrier infant. The Journal of Clinical Endocrinology and Metabolism 83(11): 3958-64, Nov 1998 Notes: DOI: 10.1210/jcem.83.11.5278.
Starr PA, Lim F, Grant FD, Trask L, Lang P, Yu L, Geller AI: Long-term persistence of defective HSV-1 vectors in the rat brain is demonstrated by reactivation of vector gene expression. Gene therapy 3(7): 615-23, Jul 1996.
Fuleihan GE, Gundberg CM, Gleason R, Brown EM, Stromski ME, Grant FD, Conlin PR.: Racial differences in parathyroid hormone dynamics. The Journal of Clinical Endocrinology and Metabolism 79(6): 1642-7, Dec 1994 Notes: This is a research peer-reviewed research publication; DOI: 10.1210/jcem.79.6.7989469.
Roberts MM, Robinson AG, Fitzsimmons MD, Grant F, Lee WS, Hoffman GE.: c-fos expression in vasopressin and oxytocin neurons reveals functional heterogeneity within magnocellular neurons. Neuroendocrinology 57(3): 388-400, Mar 1993.
Grant FD, Reventos J, Gordon JW, Kawabata S, Miller M, Majzoub JA.: Expression of the rat arginine vasopressin gene in transgenic mice. Molecular Endocrinology 7(5): 659-67, May 1993 Notes: DOI: 10.1210/mend.7.5.8100353.
Grant FD, Reventos J, Gordon JW, Kawabata S, Miller M, Majzoub JA.: Tissue-specific expression and osmotic regulation of a rat vasopressin gene in transgenic mice. Annals of the New York Academy of Sciences 689: 530-3, Jul 1993 Notes: DOI: 10.1111/j.1749-6632.1993.tb55585.x.
Grant FD, Mandel SJ, Brown EM, Williams GH, Seely EW.: Interrelationships between the renin-angiotensin-aldosterone and calcium homeostatic systems. The Journal of Clinical Endocrinology and Metabolism 75(4): 988-92, Oct 1992 Notes: DOI: 10.1210/jcem.75.4.1400892.
Gundberg, C. M., Grant, F. D., Conlin, P. R., Chen, C. J., Brown, E. M., Johnson, P. J., & LeBoff, M. S: Acute changes in serum osteocalcin during induced hypocalcemia in humans. The Journal of Clinical Endocrinology and Metabolism 72(2): 438-43, Feb 1991 Notes: DOI: 10.1210/jcem-72-2-438.
Grant FD, Conlin PR, Brown EM.: Rate and concentration dependence of parathyroid hormone dynamics during stepwise changes in serum ionized calcium in normal humans. The Journal of Clinical Endocrinology and Metabolism 71(2): 370-8, Aug 1990 Notes: DOI: 10.1210/jcem-71-2-370.
Treves ST, Fahey FH, Grant FD (editors): Pediatric Nuclear Medicine and Molecular Imaging, 4th edition. Pediatric Nuclear Medicine and Molecular Imaging, 4th edition. Treves ST, Fahey FH, Grant FD (eds.). Springer-Verlag New York, May 2014 Notes: ISBN 978-1-4614-9550-5; Dr. Grant is author/co-author of 11/32 chapters: General Aspects Pediatric Nuclear Medicine, PET/CT in Children, Thyroid, Lung, Lymphoscintigraphy, Kidneys, Vesicoureteral Reflux, Radionuclide GFR, Parathyroid/Neuroendocrine Tumors, Lymphomas, MSK Tumors.
Grant FD: Diabetes Insipidus. Pediatric Endocrinology: A Practical Clinical Guide, 3rd Edition. Radovick S, Misra M (eds.). Springer, New York, NY, Page: 215-230, Apr 2018 Notes: Book Chapter 10, ISBN: 978-3-319-73781-2.
Baron LS, Padua H, Grant F, Chow JS: Radiology for the Pediatric Hospitalist. Comprehensive Pediatric Hospital Medicine, Second Edition. Zaoutis, LB, Chiang, VW (eds.). McGraw-Hill, New York, NY, Page: 1006-1032, Dec 2017 Notes: Book Chapter ISBN-13: 978-0071829281.
Grant FD: SPECT in children. SPECT and SPECT/CT: A Clinical Guide. Kim, CK, Zukotynski, KA (eds.). Thieme, New York NY, Page: 164-180, Jun 2017 Notes: Book Chapter, ISBN-10: 1626231516.
Koo PJ, Grant FD, Treves ST: Pediatric nuclear medicine. Nuclear Medicine and PET/CT Cases. Kim CK (eds.). Oxford University Press, New York NY, Sep 2015 Notes: Book Chapter 4; ISBN 978-0199773695.
Grant FD, Kim CK: Thyroid and Parathyroid. Nuclear Medicine and PET/CT Cases. Kim CK (eds.). Oxford University Press, New York NY, Page: 291-324, Sep 2015 Notes: Book Chapter 10; ISBN 978-0199773695.
Srivatsa A, Grant FD.: Diabetes Insipidus. Pediatric Endocrinology, A Practical Clinical Guide, Second Edition. Sally Radovick, Margaret H. MacGillivray (eds.). Humana Press, 2, Feb 2013 Notes: Book Chapter 9, ISBN 978-1-607-61394-7.
Grant FD, Treves ST: Simulation in Nuclear Medicine Education. Simulation in Radiology. Robertson, HJF, Paige, JT, Bok, LR (eds.). Oxford University Press, New York NY, Page: 290-298, Jul 2012 Notes: Book Chapter 26; ISBN 978-0-19-976462.
Drubach L, Grant FD, Treves ST: A case-based approach to PET/CT in oncology. Pediatric Oncology. Gerbaudo, VH (eds.). Cambridge University Press; 1st edition, 1: 428-444, Jul 2012 Notes: Book Chapter 16, ISBN-13 : 978-0521116831.
Grant FD: Diabetes Insipidus. Pediatric Endocrinology, Contemporary Endocrinology. Radovick S, MacGillivray M (eds.). Humana Press, Page: 155-172, Feb 2003 Notes: Book Chapter 9, ISBN-13: 978-1607613947.
Grant FD. Visiting Professor, "Nuclear Medicine Imaging and Therapy of Thyroid Diseases", Mount Sinai Hospital, New York, NY, (virtual). Apr 2021.
Grant FD. Invited Speaker, "Patient Safety for Therapeutic Radiopharmaceuticals", American Pharmacists Association (APhA) Annual Meeting (virtual). Mar 2021.
Grant FD. Invited Speaker, "Nuclear Medicine Imaging and Therapy of Thyroid Disease", Radiology Conference, University of Virginia, Charlottesville, VA. Feb 2021.
Grant FD. Invited Speaker, "Functional Imaging of Brain Tumors", Radiology Conference, St. Jude Children's Research Hospital, Memphis, TN (virtual). Dec 2020.
Grant FD. Invited Speaker, "Pediatric Nuclear Medicine: Update in Gastrointestinal Imaging", Radiological Society of North America annual meeting, Chicago, IL (virtual). Dec 2020.
Grant FD. Invited Speaker, "Patient discharge and release after radioiodine I-131 therapy", Society of Nuclear Medicine and Molecular Imaging Annual Meeting (virtual). Jul 2020.
Grant FD. Invited Speaker, "Pediatric Nuclear Medicine", Radiology Conference, Mount Auburn Hospital, Cambridge MA (virtual). May 2020.
2016-2017, Editor's Recognition Award with Special Distinction, outstanding service as a reviewer of manuscripts submitted for publication in the journal Radiology, Radiological Society of North America
2001, SPR Caffey Award, Best Scientific Exhibit, International Pediatric Radiology Congress
2009, Certificate of Merit, Best Educational Exhibit, American Roentgen Ray Society (ARRS) Annual Meeting
2000, Elizabeth Dunaway-Burnham Visiting Scientist, The Geisel School of Medicine, Dartmouth College
1984, Alpha Omega Alpha, State University of New York Upstate Medical University (SUNY)
2018-present, Manuscript Reviewer, American Journal of Roentgenology
2016-present, Manuscript Reviewer, Pediatric Hematology and Oncology
2012-present, Manuscript Reviewer, Radiology
2011-present, Manuscript Reviewer, Journal of Nuclear Medicine
2011-present, Manuscript Reviewer, Pediatric Radiology
2004-present, Radiological Society of North America
2016-present, American Roentgen Ray Society
2104-present, Accreditation Council for Graduate Medical Education
- 2019-present, Vice-Chair, Residency Review Committee for Nuclear Medicine
- 2014-present, Residency Review Committee for Nuclear Medicine
2013-present, Society for Pediatric Radiology
2013-present, American College of Nuclear Medicine
- 2019-present, Ethics Committee
2012-present, The Pediatric Brain Tumor Consortium, Investigator
2004-present, Society of Nuclear Medicine and Molecular Imaging
- 2021-present, Appropriate Use Criteria for Lymphoscintigraphy workgroup
- 2020-present, Department of Energy Task Force
- 2020-present, Co-chair, Task Force on Graduate Medical Education for Radiopharmaceutical Therapy
- 2020-present, Society Historian
- 2020-present, Chair, Committee on Radioiodine Theranostics
- 2016-present, History Committee
- 2011-present, Abstract Reviewer, Annual Meeting Scientific Sessions
- 2009-present, Molecular Imaging Center of Excellence
- 2007-present, Academic, Pediatric Imaging and General Nuclear Medicine Councils
2004-present, American College of Radiology
1993-present, Endocrine Society
1991-present, American Medical Association
1991-present, American College of Physicians
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