Stephan Kadauke, MD, PhD

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Stephan Kadauke, MD, PhD, is the Assistant Director of the Cell and Gene Therapy Laboratory at Children's Hospital of Philadelphia.

Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Residency

Clinical Pathology - Massachusetts General Hospital, Boston, MA (Chief Resident)

Fellowship

Transfusion Medicine - Harvard Medical School, Cambridge, MA

Board Certification

Clinical Pathology – American Board of Pathology

Graduate Degree

PhD in Cell and Molecular Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Assistant Director, Cell and Gene Therapy Laboratory

Assistant Professor of Clinical Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2016

Kadauke S, Hiemenz MC, Lieberman DB, Roth DB, Zhao J, Watt CD, Daber RD, Morrissette JJ: Building a robust tumor profiling program: synergy between next-generation sequencing and targeted single-gene testing. PLOS One 11(4): e:0152851, April 2016 Notes: SK and MCH contributed equally.

2015

Stonestrom AJ, Hsu SC, Jahn KS, Huang P, Keller CA, Giardine BM, Kadauke S, Campbell AE, Evans P, Hardison RC, Blobel GA: Functions of BET proteins in erythroid gene expression. Blood 125(18): 2825-2834, October 2015.

2012

Kadauke S, Udugama MI, Pawlicki JM, Achtman JC, Jain DP, Cheng Y, Hardison RC, Blobel GA: Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell 150(4): 725-737, August 2012 Notes: Featured in Niemitz E (2012). Transcription programs and cell division. Nature Genetics (10)44:1079.

2011

Lamonica JM, Kadauke S, Deng W, Campbell AE, Gamsjaeger R, Wang H, Cheng Y, Billin AN, Hardison RC, Mackay JP, Blobel GA: Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proceedings of the National Academy of Sciences of the United States of America 108(22): E159-E168, May 2011 Notes: Elected by the Faculty of 1000 into top 2% of articles in biology and medicine (2011). SK and WD contributed equally.

2010

Blobel GA, Kadauke S, Wang E, Lau AW, Zuber J, Chou MM, Vakoc CR: A reconfigured pattern of MLL occupancy with mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Molecular Cell 36(6): 970-983, December 2009 Notes: Featured in Dressler GR (2010). Turning the page on epigenetic bookmarks. Developmental Cell 18(1):4-5.

Books

Chapters

2017

Kadauke S: Utilization management of blood derivatives. Utilization management in the clinical laboratory and other ancillary services. Lewandroski L, Sluss PM (eds.). Springer International Publishing, Cham, Switzerland, Page: 135-140, December 2017.

Posters and Presentations

2018

Hawkins J, O'Doherty U, Kadauke S: A proposal to evaluate the effect of gamma irradiation on the survival of transfused red cells in sickle cell disease patients. American Society for Apheresis 2018 Annual Meeting, Chicago, IL April 2018 Notes: Poster Presentation.

Kadauke S: Teaching reproducible data analysis to medical doctors. rstudio::conf 2018, San Diego, CA February 2018 Notes: Electronic Poster Presentation.

Invited Lectures

2018

Kadauke S. "Breaking up with Excel: a newbie's introduction to the R statistical programming language", Mass Spectrometry: Applications to the Clinical Lab 10th Annual Conference, Palm Springs, CA. Jan, 2018.

Kadauke S. "Advances in the diagnosis and management of thrombotic thrombocytopenic purpura", Weill-Cornell Medicine, New York, NY. Jan, 2018.

2017

Kadauke S. "Advances in the diagnosis and management of thrombotic thrombocytopenic purpura", Memorial Sloan Kettering Cancer Center, New York, NY. Dec, 2017.

Kadauke S. "Advances in the diagnosis and management of thrombotic thrombocytopenic purpura", Stanford Blood Center, Palo Alto, CA. Dec, 2017.

Kadauke S. "Advances in the diagnosis and management of thrombotic thrombocytopenic purpura", University of Maryland Medical Center, Baltimore, MD. Nov, 2017.

Kadauke S. "Advances in the diagnosis and management of thrombotic thrombocytopenic purpura", Children's Hospital of Philadelphia, Philadelphia, PA. Mar, 2017.

Awards and Honors

2013, Saul Winegrad Award for Outstanding Dissertation, University of Pennsylvania
2013, Roy G. Williams Award for Meritorious Research in Basic Medical Sciences, University of Pennsylvania
2009-2011, American Heart Association Pre-Doctoral Fellowship, University of Pennsylvania
2005-2009, Benjamin and Mary Siddons Measey Foundation Fellowship, University of Pennsylvania
2004, Phi Beta Kappa - Early Induction for Top 2% of Graduating Class, Columbia University

Editorial and Academic Positions

Editorial Positions

2017-present, Peer Reviewer, Transfusion Medicine Reviews

Leadership and Memberships

Memberships in Professional Organizations

International

2017-present, AABB

National

2018-present, American Society of Apheresis (ASFA)