
Michael L. O'Byrne
Locations: Main Building
About Michael L. O'Byrne
Michael L. O’Byrne, MD, MSCE, is an interventional cardiologist in the Cardiac Center at Children’s Hospital Philadelphia (CHOP). He is a magna cum laude graduate of Harvard University who earned his MD from Columbia University’s College of Physicians and Surgeons. In 2014, he completed his Master of Science in Clinical Epidemiology at the University of Pennsylvania.
Dr. O’Byrne’s primary clinical focus is on performing cardiac catheterization procedures for children with congenital heart disease, a treatment option that’s less invasive than open heart surgery. He combines his clinical practice with work as a clinical epidemiologist, doing research aimed at understanding how to improve quality of care for children with cardiac disease and their families.
“I think this is a natural combination,” he explained. “My research is grounded by my clinical work, which helps identify and articulate questions that are important to our patients and their families. At the same time, my research informs my clinical care, helping me identify an approach based on the best possible evidence.”
As a researcher, Dr. O’ Byrne receives funding from the NIH/NHLBI. He has authored and peer-reviewed dozens of research papers and abstracts. He was honored in 2017 with the Christopher J White, MD, Early Career Reviewer Award, and was a 2018 AHA Council for Cardiovascular Disease in the Young, Young Investigator Award Finalist.
The collaborative nature of the team at CHOP’s Cardiac Center is a source of inspiration for Dr. O’Byrne. “As interventional cardiologists, we are constantly moving forward together to develop new techniques and ways to help children and their families,” he says. “That means using cutting-edge technology and adapting existing techniques to new applications, both on our own in the cath lab and in cooperation with our surgical colleagues and other cardiologists.”
Titles
Attending Cardiologist
Assistant Program Director, Cardiac Center T-32 Training Program
Director, Cardiac Center Clinical Research Core
Assistant Professor of Pediatrics (CE track), Perelman School of Medicine at the University of Pennsylvania
Certifications
Pediatric Cardiology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics
Awards and Honors
2019, Young Physician-Scientists Award, American Society for Clinical Investigation
2018, Young Investigator Award Finalist, American Heart Association Council on Cardiovascular Disease in the Young
2017, The Christopher J White, MD, Early Career Reviewer Award
2010, Senior Resident Clinician Award (The Children’s Hospital of Philadelphia graduation award for excellence in clinical care)
2007, Marie Nercessian Award for Compassionate Care of Patients (Columbia University College of Physicians and Surgeons)|
2007, Rebecca Schwartz Prize in Pediatric Cardiology (Columbia University College of Physicians and Surgeons)
2007, Arnold P. Gold Humanism Honor Society
2006, AOA Debbie Glaser Medical Student Essay Contest: Honorable Mention
Leadership and Memberships
Memberships in Professional Organizations
International
2020-present, Congenital Cardiac Catheterization Project on Outcomes (C3PO) collaborative
- 2021-present, Research and Publications Committee
- 2020-present, Steering Committee
2013-present, Society for Cardiac Angiography and Intervention
- 2018-present, Fellow
National
2024-present, Cardiac Networks United, Director
2021-present, Pediatric Cardiac Research Initiative in Imaging to Support Mentoring
2021-present, Congenital Cardiac Research Collaborative
2018-present, Society for Pediatric Research
2018-present, American Thoracic Society
2018-present, IMPACT®
- 2018-present, Research and Publications Committee
2010-present, American College of Cardiology
- 2015-present, Associate Fellow
2005-present, American Heart Association
- 2025-present, CVDY Council Congenital Heart Defects Committee
Editorial and Academic Positions
Editorial Positions
2023-present, Editorial Board Member, Catheterization Cardiovascular Interventions
2020-present, Editorial Board Member, Circulation: Cardiovascular Quality and Outcomes
2020-present, Editorial Board Member, American Heart Journal
Academic and Institutional Committees
2024-present, Cardiac Center Data Governance Committee
2024-present, Cardiology Fellowship Core Faculty
2022-present, Cardiology Fellowship Selection Committee,
2022-present, Cardiology Fellowship Clinical Competency Committee
2022-present, Catheterization Laboratory Database Committee, Chair
2021-present, Department of Pediatrics Chairs Research Council
2021-present, Cardiac Center Scientific Review Committee, Chair
2021-present, Interventional Cardiology Data Use Committee, Director
2021-present, Department of Pediatrics Research Council
2018-present, Hospital Sedation Committee
Education & training
Graduate Degree
Master of Science in Clinical Epidemiology (MSCE) - University of Pennsylvania, Philadelphia, PA
Medical Degree
MD - Columbia University College of Physicians and Surgeons, New York, NY
Internship
Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA
Residency
Pediatrics - The Children’s Hospital of Philadelphia, Philadelphia, PA
Fellowship
Advanced Fellow in Interventional Cardiology - Children’s Hospital of Philadelphia, Philadelphia, PA
Advanced Fellow in Cardiovascular Research and Interventional Cardiology - Children’s Hospital of Philadelphia, Philadelphia, PA
Pediatric Cardiology - Children’s Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2025
112.Vega TF, Huber M, Jensen EA, Avitabile CM, Lorch SA, Gibbs KA, O'Byrne ML, Frank DB, Bamat NA. : Pulmonary vasodilator use in very preterm infants in United States children's hospitals. J Perinatol 2025 Notes: e-published ahead of print.
95. Ali F, Yeh MJ, Walshe FE, Bergersen L, Gauvreau K, Barry OM, Boe BA, Holzer RJ, De Decker R, Jenkins K, Kreutzer J, Kumar RK, Lozier J, O'Byrne ML, Polivenok I, Ronderos M, Hasan B, Quinn BP.: Comparative Congenital Cardiac Catheterization Registry Analysis From the United States and Low- and Middle-Income Countries. JACC Advances 4(4): 101649, 2025 Notes: 2025. 4(4): 101649.
Barak-Corren Y,Obsekov V, Gupta M, Herz C, Amin S , Lasso A, O'Byrne ML, Gillespie MJ Jolley MA.: Image-Derived Modeling to Assess Coronary Proximity in Patients Undergoing Transcatheter Pulmonary Valve Replacement With Self-Expanding Valves. Catheter Cardiovasc Interv 2025 Notes: 2025. Epublished ahead of print. PMID: 40045877.
Barry OM, Hasan BS, Aslam N, Batlivala SP, Crystal MA, Trucco SM, Gudausky T, Holzer RJ, Kreutzer J, Nicholson G, O'Byrne ML, Quinn BP, Veeram Reddy SR, Salavitabar A, Boe BA.: Evaluating Procedural Performance: A Composite Outcome for Atrial Septal Defect and Patent Ductus Arteriosus Closures. J Soc Cardiovasc Angiogr Interv 2025 Notes: 4(2): 102459. PMID: 40109707. PMCID: PMC11916790. PMCID: PMC11916790
Cianciulli AR, Sulentic A, Wang Y, Daemer M, Amin S, Joyce J, Lasso A, Otero HJ, Cohen MS, Fuller S, Nuri MAK, Tang J, O'Byrne ML, Jolley MA.: Volume Rendering of CT Images to Inform Closure of Complex Ventricular Septal Defects. JACC Case Reports 2025 Notes: 19(30 6 Pt. 1): 102827. P<ID: 40118631. PMCID: PMC12011141. PMCID: PMC12011141
Edelson JB, Huang J, Wang Z, Tam V, Lefktowitz D, O'Connor MJ, White R, Ha L, Wittlieb-Weber CA, Rossano JW, Lin K, Cousino MK, Lane-Fall M, O'Byrne ML. : Identifying the determinants of health-related quality of life in children after heart transplant. JHLT Open 2025 Notes: JHLT Open, 2025.8: 100250. PMID: 40292044. PMCID: PMC12022506. PMCID: PMC12022506
Gupta M, Amin S, Cianciulli A, Barak-Corren Y, Pinter C, Dewey H, Lasso A, Russell W, Colello S, Gartenberg AJ, Obsekov V, Williams T, Silvestro E, O'Byrne ML, Glatz AC, Jolley MA. : Quantitative Analysis of 3D Anatomy to Inform Planning of Ductal Arteriosus Stenting. Catheter Cardiovasc Interv 2025 Notes: 2025. Online ahead of print. PMID: 41052008.
Gupta M, Leeth EB, Barak-Corren Y, Gartenberg AJ, Silvestro E, O'Byrne ML, Callahan R.: Balloon Dilation Technique Influences Stent Shortening and Intentional Stent Fracture During Overexpansion of Drug-Eluting Stents: A Bench-Testing Study. 2025. Epublished ahead of print. PMID: 39887520. Catheter Cardiovasc Interv, 2025 Notes: 2025. Epublished ahead of print. PMID: 39887520.
O'Byrne ML, Boscamp NS, Gauvreau K, Rahman GR, Barry OM, Batlivala SP, Bergersen L, Bjornlund EC, Bocks ML, Doyle T, Farias M, Goldstein BH, Holzer RJ, Reddy SRV, Salavitabar A, Sathanandam S, Whiteside W, Quinn BP. : Congenital Cardiac Catheterization Risk Assessment in Infants Under 2.5 kg. , Pediatric Cardiology 2025 Notes: 2025. Online ahead of print. PMID: 40152982.
O'Byrne ML, Sharma P, Huang J, Smith CL, Tang J, Callahan R, Edelson JB, DoriY, Gillespie MJ, Rome JJ, Glatz AC.: Response of health-related quality of life following pediatric/congenital cardiac catheterization procedures. Am Heart J Page: 71-83, 2025 Notes: 2025, 281: 71-83. PMID: 39643098. PMCID: PMC11981091. PMCID: PMC11981091
Real Time Assessment of Pulmonary Blood flow in Pulmonary Vein Stenosis Using The Fluoroscopic Flow Calculator. : Barak-Corren Y, Gupta M, Dori Y, Tang J, Smith CL, Rome JJ, Gillespie MJ, Jolley MA, O'Byrne ML, Callahan R. J Soc Cardiovasc Angiogr Interv. 4(4), 2025 Notes: J Soc Cardiovasc Angiogr Interv. 2025. 4(4): 102639.
Ruppel H, Huang L, Petit CJ, Qureshi AM, Bonafide CP, Foglia EE, Feldman J, Lane-Fall MB, Lynch JM, Chien A, Dunn M, O'Byrne ML.: Protocol for a multisite, observational clinical study of the association between skin color and pulse oximeter accuracy in children undergoing cardiac catheterization PACH study BMJ Open 2025 Notes: (PACH study). BMJ Open, 15(4): e100391. PMID: 40187780. PMCID: PMC11973777. PMCID: PMC11973777
Yeh MJ, Bergersen L, Gauvreau K, Akhtar S, Batliva SP, Bocks ML, Holzer R, O'Byrne ML, Shahanavaz S, Trucco SM, Zellers T, Armstrong AK.: Association between procedure duration and adverse events in congenital cardiac catheterization. Cardiol Young 2025 Notes: Cardiol Young, 2025, 35(1): 162-169. PMID: 39834061.
Yeh MJ, Bjornlund E, Gauvreau K, Ali F, Aslam N, Batlivala SP, Berman D, Bocks ML, Chenault K, Doyle T, Gudausky T, Hainstock M, Holzer R, Ibla J, O'Byrne ML, Quinn BP, Shahanavaz S, Sharma R, Trucco SM, Whiteside W, Bergersen L, Armstrong AK: Formulation of Quality Improvement Methodology for Risk Mitigation in Congenital Cardiac Catheterization. Pediatr Cardiology 2025.
2024
Cumulative Radiation Exposure and Lifetime Cancer Risk in Patients With Tetralogy of Fallot Requiring Early Intervention: Wong-Siegel JR, Glatz AC, McCracken C, Lee C, Kitahara CM, Veiga LHS, Zhang Y, Goldstein BH, Petit CJ, Qureshi AM, Nicholson GT 3rd, Law MA, Meadows J, Shahanavaz S, O'Byrne ML, Batlivala SP, Pettus J, Beshish A, Mascio CE, Romano JC, Stack KO, Asztalos I, Downing TE, Zampi JD. JACC Adv. September 2024 Notes: 2024 Sep 6;3(10):101239. PMID: 39290814.
Zampi JD, Ilardi DL, McCracken CE, Zhang Y, Glatz AC, Goldstein BH, Petit CJ, Qureshi AM, Goldberg CS, Law MA, Meadows JJ, Shahanavaz S, Batlivala SP, Maskatia SA, O'Byrne ML, Ligon RA, Pettus JA, Beshish A, Romano JC, Stack KO, Khan HQ, Parekh S, Nicholson GT: Comparing Parent Perception of Neurodevelopment after Primary versus Staged Repair of Neonatal Symptomatic Tetralogy of Fallot. J Pediatr, Online ahead of print October 2024.
91.Rastogi R, Okunowo O, Faerber J, Mavrouids CD, Whitworth H, Giglia TM, Witmer C, Raffini LJ, O'Byrne ML.: Incidence, Management, and Hospital Outcomes of Pediatric Pulmonary Embolism Managed at Tertiary Pediatric Hospitals in the United States. JACC Advances 2024 Notes: In press
Barack-Corren, Y, Gupta M, Tang J, Smith CL, Callahan R, Dori Y, Rome JJ, Gillespie MJ, O'Byrne ML.: From Text to Data. Automatically Extracting Data From Catheterization Reports Using Generative Artificial Intelligence. JSCAI 2024 Notes: 4(3PartB): 102242. PMCID: PMC11993886
Barak-Corren Y, Herz C, Lasso A, Dori Y, Tang J, Smith CL, Callahan R, Rome JJ, Gillespie MJ, Jolley MA, O'Byrne ML.: Calculating Relative Lung Perfusion Using Fluoroscopic Sequences and Image Analysis: The Fluoroscopic Flow Calculator. Circ Cardiovasc Interevent 17(1), 2024.
Lemley BA, Okunowo O, Ampah SB, Wu L, Shinohara R, Goldberg D, Rychik J, Glatz AC, Amaral S, O'Byrne ML. : Effect of Patient Factors, Center and Era on Fontan Timing. Am Heart J Page: 156-163, 2024.
Nicholson GT, Zampi JD, Glatz AC, Goldstein BH, Petit CJ, Zhang Y, McCracken CE, Qureshi AM, Goldberg CS, Romano JC, Law MA, Meadows JJ, Shahanavaz S, Batlivala SP, Maskatia SA, Beshish A, O'Byrne ML, Ligon RA, Stack KO, Khan HQ, Parekh S, Ilardi DL.: Health-Related Quality of Life After Neonatal Treatment of Symptomatic Tetralogy of Fallot: Insights from the Congenital Cardiac Research Collaborative. Pediatr Cardiol. 2024 Online ahead of print. PMID: 39305323. Pediatr Cardiology 2024.
O'Byrne ML, Baxelbaum K, Tam V, Griffis H, Pennington ML, Hagerty A, Naim MY, Nicolson SC, Shillingford AJ, Sutherland TN, Hampton LE, Gebregiorgis NG, Nguyen T, Ramos E, Rossano JW: Association of Postnatal Opioid Exposure and 2-Year Neurodevelopmental Outcomes in Infants Undergoing Cardiac Surgery. J Am Coll Cardiol, 84(11): 1010-1021, 2024. PMCID: PMID: 39232628
Quinn BP, Gunnelson LC, Kotin SG, Gauvreau K, Yeh MJ, Hasan B, Lozier J, Barry OM, Shahanavaz S, Batlivala SP, Salavitabar A, Foerster S, Goldstein B, Divekar A, Holzer R, Nicholson GT, O'Byrne ML, Whiteside W, Bergersen L. : Catheterization for Congenital Heart Disease Adjustment for Risk Method II. Circ Cardiovasc Interv 17(3), 2024 Notes: PMID: 38258562.
2023
Janson CM, Shah MJ, Kennedy KF, Iyer VR, Behere S, Sweeten TL, O'Byrne ML: Association of Weight With Ablation Outcomes in Pediatric Wolff-Parkinson-White: Analysis of the NCDR IMPACT Registry. JACC Clin Electrophysiol 9(1): 73-84, Jan 2023.
Ruppel H, Makeneni S, Faerber JA, Lane-Fall MB, Foglia EE, O'Byrne ML, Bonafide CP : Evaluating the accuracy of pulse oximetry in children according to race. JAMA: Pediatr Page: In Press, Jan 2023 Notes: E230071.
Barry OM, Gudausky TM, Balzer DT, Bocks ML, Boe BA, Callahan R, El-Said H, Faria MJ, Foerster S, Goldstein BH, Holzer RJ, Janssen D, Levy P, O'Byrne ML, Rahman G, Sathanandam S, Shahanavaz S, Whiteside W, Turner M: Safety and Short-Term Outcomes for Infants <2.5 kg Undergoing PDA Device Closure: A C3PO Registry Study. Pediatr Cardiol 44(6): 1406-1413, Aug 2023.
O'Byrne ML, Song L, Huang J, Lemley BA, Goldberg DJ, Gardner MM, Ravishankar C, Rome JJ, Glatz AC: Attributable Mortality Benefit of Digoxin Treatment in Hypoplastic Left Heart Syndrome After Norwood Operation. Am Heart J 263: 35-45, September 2023.
Zampi JD, Heinrich KP, Bergersen L, Goldstein BH, Batlivala SP, Fuller S, Glatz AC, O'Byrne ML, Marino B, Afton K, Lowery R, Yu S, Goldberg CS: Neurocognitive function and health-related quality of life in adolescents and young adults with CHD with pulmonary valve dysfunction. Cardiol Young. 30: 1-8, November 2023.
Holzer RJ, Bergersen L, Thomson J, Aboulhosn J, Aggarwal V, Akagi T, Alwi M, Armstrong AK, Bacha E, Benson L, Bokenkamp R, Carminati M, Dalvi B, DiNardo J, Fagan T, Fetterly K, Ing FI, Kenny D, Kim D, Kish E, O'Byrne M, O'Donnell C, Pan X, Paolillo J, Pedra C, Peirone A, Singh HS, Sondegaard L, Hijazi ZM. PICS/AEPC/APPCS/CSANZ/SCAI/SOLACI: : Expert Consensus Statement on Cardiac Catheterization for Pediatric Patients and Adults With Congenital Heart Disease. JSCAI 2023 Notes: E published ahead of print.
Gartenberg AJ, Krishnamurthy G, Srinivasan A, Escobar FA, Brownell JN, Mamula P, O'Byrne ML, Dori Y, Smith CL: Intrahepatic and Periduodenal Embolization for Protein-Losing Enteropathy Patients with Congenital Heart Disease. J Am Coll Cardiol 81(25): June, 2476-2478 2023.
Gartenberg AJ, Okunowo O, Dori Y, Smith CL, Gaynor JW, Masco CE, Rome JJ, Gillespie MJ, Glatz AC, O'Byrne ML: Association of Interstage Monitoring Era and Likelihood of Hemodynamic Compromise at Intervention for Recoarctation Following the Norwood Operation. J Am Heart Assoc 2023 Notes: on-line ahead of print.
Holzer R, Batlivala SP, Boe B, Goldstein B, Gudausky T, Hasan B, O'Byrne M, Quinn B, Sathanandam S, Shahanavaz S, Trucco SM, Zampi JD, Bergersen L.: The Need for Surgery After Vascular or Cardiac Trauma, or Technical Adverse Events in the Congenital Cardiac Catheterization Laboratory. Pediatr Cardiol 44: 795-805, 2023.
Lemley BA, Wu L, Roberts AL, Shinohara RT, Quarshie WO, Qureshi AM, Smith CL, Dori Y, Gillespie MJ, Rome JJ, Glatz AC, Amaral S, O'Byrne ML. : Trends in Ductal Arteriosus Stent Versus Blalock-Thomas-Taussig Shunt Use and Comparison of Cost, Length of Stay, and Short-Term Outcomes in Neonates With Ductal-Dependent Pulmonary Blood Flow: An Observational Study Using the Pediatric Health Information Systems Database. J Am Heart Assoc 12(23), 2023 Notes: e030575.
2022
O'Byrne ML, Faerber JA. Katcoff H, Huang J, Edelson JB, Finkelstein DM, Lemley B, Janson CM, Avitabile CA, Glatz AC, Goldberg DJ: Prevalent Pharmacotherapy of United States Fontan Survivors: A study utilizing data from the MarketScan Commercial and Medicaid Claims Databases. Am Heart J 243(4): 158-166, January 2022.
Quinn BP, Yeh M, Gauvrea K, Ali F, Balzer D, Barry O, Batlivala S, Berman DP, Foerster S, Goldstein BH, Hainstock MR, Holzer R, Janssen D, O'Byrne ML, Shirley L, Trucco S, Whiteside W, Bergersen LJ : Procedural Risk in Congenital Cardiac Catheterization (PREDIC3T). J Am Heart Assoc 11(1): e022832, January 2022.
Smith CL, Liu M, Saravanan M, Dewitt AG, Biko DM, Pinto EM, Escobar FA, Krishnamurthy G, Brownell JN, Mamula P, Glatz A, Gillespie MJ, O'Byrne ML, Ravishankar C, Rome JJ, Dori Y: Liver lymphatic anatomy and role in systemic lymphatic disease. Eur Radiol 32(1): 112-121, January 2022.
Berger JH, Faerber JA, Chen F, Lin KY, Brothers JA*, O'Byrne ML*: Adherence with lipid screening guidelines in children with acquired and congenital heart disease: An observational study using data from The Marketscan Commercial and Medicaid Databases. J Am Heart Assoc 111(7): e024197, February 2022 Notes: * denotes shared senior authorship. PMCID: PMC9075474
Chaszczewski KJ, Nicholson GT, Shahanavaz S, Dori Y, Gillespie MJ, O'Byrne ML, Rome JJ, Glatz AC: Stent Angioplasty for Post-Operative Coronary Artery Stenosis in Infants. World J Pediatr Congen Heart Surg 13(2): 203-207, March 2022.
Dietzman TW, Soria S, DePaolo J, Gillespie MJ, Mascio C, Dori Y, O'Byrne ML, Rome JJ, Glatz AC: Influence of Antegrade Pulmonary Blood Flow on Outcomes of Superior Cavopulmonary Connection Ann Thorac Surg 114(5): 1771-1777, Mar 2022.
O'Byrne ML, Glatz AC, Huang YV, Kelleman MS, Petit CJ, Qureshi AM, Shahanavaz S, Nicholson GT, Batlivala S, Meadows JJ, Zampi JD, Law MA, Romano JC, Mascio CE, Chai PJ, Maskatia S, Asztalos IB, Beshish A, Pettus J, Pajk AL, Healan SJ, Eilers LF, Merritt T, McCracken CE, Goldstein BH : Comparative Costs of Management Strategies for Neonates with Symptomatic Tetralogy of Fallot: A study combining data from the Congenital Cardiac Research Collaborative and The Pediatric Health Information Systems Database J Am Coll Cardiol 79(12): 1170-1180, March 2022. PMCID: PMC9584799
Vaiyani D, Saravanan M, Dori Y, Pinto E, Gillespie MJ, Rome JJ, Goldberg DJ, Smith SL, O'Byrne ML, DeWitt AG, Ravishankar C: Post-operative Chylothorax in Patients with Repaired Transposition of the Great Arteries. Pediatr Cardiol 43(3): 685-690, March 2022.
Janson CM, Millenson ME, Okunowo O, Dai D, Christmyer Z, Tan RB, Iyer VR, Shah MJ, O'Byrne ML: Incidence of Life-Threatening Events in Children with Wolff-Parkinson-White Syndrome: Analysis of a Large Claims Database. Heart Rhythm 19(4): 642-647, April 2022.
O'Byrne ML, McHugh KE, Huang J, Song L, Griffis H, Anderson BR, Bucholz EM, Chanani NK, Elhoff JJ, Handler SS, Jacobs JP, Li JS, Lewis AB, McCrindle BW, Pinto NM, Sassalos P, Spar DS, Pasquali SK, Glatz AC: Cumulative In-Hospital Costs Associated with Single-Ventricle Palliation. JACC: Advances 1(2): 1-10, Jun 2022 Notes: NOT INDEXED FOR PMID.
Smith CL, Dori Y, O'Byrne ML, Glatz AC, Gillespie MJ, Rome JJ: Transcatheter Thoracic Duct Decompression for Multicompartment Lymphatic Failure After Fontan Palliation. Circ Cardiovasc Interv 15(7): e011733, Jul 2022.
Nash D, Katcoff H, Faerber JA, Iyer VR, Shah MJ, *O'Byrne ML, Janson CM: Impact of Device Miniaturization on Implantable Loop Recorder Utilization in the Pediatric Population: An analysis of the Markerscan Commercial and Medicaid Databases. J Am Heart Assoc 11(16): e024112, Aug 2022 Notes: *co-senior author. PMCID: PMC9496290
Quinn B, Barry OM, Batlivala SP, Boe BA, Glatz AC, Gauvreau K, Goldstein BH, Gudausky TM, Hainstock R, Holzer RJ, Nicholson GT, Trucco SM, Whiteside W, Yeh M, Bergersen L, O'Byrne ML: Changes in Practice/Outcomes of Pediatric/Congenital Catheterization in Response to the First Wave of COVID. JACC: Advances 1(5): 100143, Nov 2022. PMCID: PMC9710529
Yeh MJ, Gauvreau K, Armstrong AK, Batlivala SP, Callahan R, Gudausky TM, Hainstock MR, Hasan B, Nicholson GT, O'Byrne ML, Shahanavaz S, Trucco S, Zampi J, Bergersen L: Early Post-Operative Congenital Cardiac Catheterization Outcomes: A Multicenter Study. Ann Thorac Surg Page: In Press, Nov 2022 Notes: E-published ahead of print.
O'Byrne ML, Song L, Huang J, Lemley BA, Goldberg DJ, Gardner MM, Ravishankar C, Rome JJ, Glatz AC: Attributable Mortality Benefit of Digoxin Treatment in Hypoplastic Left Heart Syndrome After Norwood Operation. Am Heart J 2022 Notes: Online ahead of print
Savla JJ, Kelly B, Krogh E, Smith CL, Krishnamurthy G, Glatz AC, DeWitt AG, Pinto EM, Ravishankar C, Gillespie MJ, O'Byrne ML, Escobar FA, Rome JJ, Hjortdal V, Dori Y. : Occlusion Pressure of the Thoracic Duct in Fontan Patients with Lymphatic Failure: Does Dilatation Challenge Contractility? W J Pediatrc and Congenit Heart Surg 13(6): 737-744, 2022.
Yeh MJ, Bergesen L, Gauvreau K, Barry OM, Batlivala SP, Bjornlund E, Boe B, Caneo LF, Croti UA, Doyle T, Furnaz S, Moraes R, O'Byrne ML, de Oliveira Paes, Palacios-Macedo A, Pechikov D, Sandoval NF, Sen S, Stajevic M, Ferreira Travessa MA, Jenkins KJ: COVID-19 international experience in paediatric patients with congenital heart disease. Heart Page: doi: 10.1136, Dec 2022 Notes: epub ahead of print.
2021
O'Byrne ML, Kennedy KF, Steven J, Hill KD, Chamberlain RC, Millenson ME, Dori Y, Gillespie MJ, Rome JJ, Glatz AC: Outcomes of operator directed sedation and general anesthesia in the pediatric/congenital catheterization laboratory: A study utilizing data from the IMproving Pediatric And Congenital Treatment® (IMPACT) Registry. JACC Cardiovasc Intervent 14(4): 401-413, February 2021. PMCID: PMC7932684
O'Byrne ML, Song L, Huang J, Goldberg D, Gardner MM, Ravishankar C, Rome JJ, Glatz AC: Trends in Discharge Prescription of Digoxin After Norwood Operation: An Analysis of Data fromthe Pediatric Health Information System (PHIS) Database. Pediatr Cardiol 42(4): 793-803, April 2021. PMCID: PMC8113119
Faerber JA, Huang J, Zhang X, Song L, DeCost G, Mascio CE, Ravishankar C, O'Byrne ML, Naim MY, Kawut SM, Goldmuntz E, Mercer-Rosa L: Identifying Risk Factors for Complicated Post-operative Course in Tetralogy of Fallot Using a Machine Learning Approach. Front Cardiovasc Med 8: 685855, July 2021. PMCID: PMC8339319
Janson CM, Shah MJ, Kennedy KF, Iyer VR, Sweeten TL, Glatz AC, Steven JM, O'Byrne ML: Comparison of Outcomes of Pediatric Catheter Ablation by Anesthesia Strategy: A Report from the NCDR® IMPACT Registry. Circ: Arrhyth and Electrophysiol 14(7): e009849, July 2021.
Chaszczewski KC, Huang J, Fuller S, Smith CL, Dori Y, Glatz AC, Gillespie MJ, Rome JJ, O'Byrne ML: Impact of Transcatheter Pulmonary Artery Intervention Following Superior Cavopulmonary Connection on Pulmonary Artery Growth. W J Pediatr Congen Cardiovasc Surg 12(5): 635-642, September 2021.
Lemley BA, Biko DM, Dewitt AG, Glatz AC, Goldberg DJ, Saravan M, O'Byrne ML, Pinto E, Ravishankar C, Rome JJ, Smith CL, Dori Y: Intrahepatic Dynamic Contrast―Enhanced Magnetic Resonance Lymphangiography: Potential Imaging Signature for Protein―Losing Enteropathy in Congenital Heart Disease. J Am Heart Assoc 10(19): e021542, October 2021.
2020
Ghosh RM, Griffis HM, Glatz AC, Rome JJ, Smith CL, Gillespie MJ, Whitehead KK, O'Byrne ML, Biko DM, Ravishankar C, Dewitt AG, Dori Y.: Prevalence and Cause of Early Fontan Complications: Does the Lymphatic Circulation Play a Role? J Am Heart Assoc 9: e015318, Apr 2020.
Nam HH, Herz C, Lasso A, Drouin S, Posada A, Morray B, O'Byrne ML, Paniagua B, Joffe D, Mackensen B, Rogers L, Fichtinger G, Jolley MA.: Simulation of Transcatheter Atrial and Ventricular Septal Defect Device Closure Within Three-Dimensional Echocardiography-Derived Heart Models on Screen and in Virtual Reality. J Am Soc Echocardiogr 33: 641-644, May 2020.
O'Byrne ML, DeCost G, Katcoff H, Savla JJ, Chang J, Goldmuntz E, Groeneveld PW, Rossano JW, Faerber JA, Mercer-Rosa L.: Resource Utilization in the First 2 Years Following Operative Correction for Tetralogy of Fallot: Study Using Data From the Optum's De-Identified Clinformatics® Data Mart Insurance Claims Database. J Am Heart Assoc 9: e016581, Aug 2020.
Berger JH, Chen F, Faerber JA, *O'Byrne ML, *Brothers JA.: Adherence with lipid screening guidelines in standard- and high-risk children and adolescents. Am Heart J 232: 39-46, Oct 2020 Notes: * co-senior authorse-published ahead of print.
Tomasulo CE, Gillespie MJ, Munson D, Demkin T, O'Byrne ML, Dori Y, Smith CL, Rome JJ, Glatz AC.: Incidence and fate of device-related left pulmonary artery stenosis and aortic coarctation in small infants undergoing transcatheter patent ductus arteriosus closure. Catheter Cardiovasc Interv 96: 889-897, Oct 2020.
Bhatt SM, O'Byrne ML, McBride M, Paridon S, Goldmuntz E, Mercer-Rosa L: Chronotropic Response and Pulmonary Function are Associated with Exercise Performance in Children and Adolescents with Repaired Tetralogy of Fallot Independent of Cardiac Function. Cong Heart Dis (in press) 2020 Notes: In press.
Ghosh RM, Griffis H, Glatz AC, Rome JJ, Smith CL, Gillespie MJ, Whitehead KK, O'Byrne ML, Biko DM, Ravishankar C, Dewitt AG, Dori Y: Prevalence and Etiology of Early Fontan Complications: Does the Lymphatic Circulation Play a Role. J Am Heart Assoc 9(7): e015318, 2020.
Ghosh RM, Mascio CE, Silvestri E, O'Byrne ML, Whitehead KK: A Road-Map for Collaterals: Use of 3D Techniques in Tetralogy of Fallot Pulmonary Atresia With MAPCAs. JTCVS Tech 1: 82-85, 2020.
O'Byrne ML, Faerber JA, Katcoff H, Frank DB, Davidson A, Giglia TM, Avitabile CM: Variation in the use of pulmonary vasodilators in children and adolescents with pulmonary hypertension: A study using data from the Marketscan® Insurance Claims Database. Pulm Circ 10(3): 1-9, 2020.
O'Byrne ML, Huang J, Asztalos I, Smith CL, Dori Y, Gillespie MJ, Rome JJ, Glatz AC.: Pediatric/Congenital Cardiac Catheterization Quality: An Analysis of Existing Metrics. JACC Cardiovasc Interv 13: 2853-2864, Dec 2020.
Tomasulo CE, Gillespie MJ, Munson D, Demkin T, O'Byrne ML, Dori Y, Smith CL, Rome JJ, Glatz AC: Outcomes Following Transcatheter Closure of Patent Ductus Arteriosus in Small Infants: a Focus on the Fate of Device-Related Left Pulmonary Artery Stenosis and Aortic Coarctation. Catheter Cardiovasc Intervent 96(4): 889-897, 2020.
2019
O'Byrne ML, McBride M, Pardion S, Goldmuntz E: Association of Habitual Activity and Body Mass Index in Survivors of Congenital Heart Surgery: A study of children and adolescents with tetralogy of Fallot, transposition of the great Arteries, and Fontan palliation. W J Pediatr Congen Heart Surg 9(2): 177-184, 2018.
Fuller S, Ramchandran A, Awh K, Faerber JA, Nicolson SC, O'Byrne ML, Mascio CE, Kim YY: Comparison of Outcomes of Pulmonary Valve Replacement in Adult vs. Pediatric Hospitals: Institutional Influence. Eur J Cardio Surg 56(5): 891-897, April 2019.
Goldstein BH, O'Byrne ML, Petit CJ, Qureshi AM, Griffis HM, France A, Kelleman MS, McCracken CE, Mascio CE, Shashidharan S, Ligon RA, Whiteside W, Wallen WJ, Agrawal H, Aggarwal V, Glatz AC: Differences in Cost of Care by Palliation Strategy for Infants With Ductal-Dependent Pulmonary Blood Flow. Circulation: Cardiovascular Intervention 12(4): e007232, April 2019.
O'Byrne ML, Millenson ME, Steven JM, Gillespie MJ, Dori Y, Glatz AC, Rome JJ: Operator-directed procedural sedation in the congenital cardiac catheterization laboratory. JACC CV Intervent 12(9): 835-843, April 2019.
Grant EK, Kanter JP, Olivieri LJ, Cross RJ, Cronin I, Campbell-Washburn A, Faranesh AZ, Hamann KS, O'Byrne ML, Slack MC, Lederman RJ, Ratnayaka K: X-Ray Fused with MRI (XFM) Guidance of Pre-selected Transcatheter Congenital Heart Disease Interventions. Catheter Cardiovasc Intervent Page: doi: 10.1002, May 2019 Notes: epub ahead of print.
O'Byrne ML, Glatz AC, Faerber JA, Seshadri R, Millenson M, Mi L, Shinohara RT, Dori Y, Gillespie MJ, Rome JJ, Kawut SM, Groeneveld PW: Inter-hospital variation in the costs of pediatric/congenital cardiac catheterization procedures: An analysis of data from the Pediatric Health Information Systems Database. Journal of American Heart Association 8(9): doi: 10.1161, May 2019 Notes: e-published ahead of print.
O'Byrne ML, Kennedy KF, Jayaram N, Bergersen LJ, Gillespie MJ, Dori Y, Silber JH, Kawut SM, Rome JJ, Glatz AC: Failure to rescue as an outcome metric for pediatric and congenital cardiac catheterization programs: An analysis of data from the IMProving Adult and Congenital Treatment ® (IMPACT) Registry. Journal of the American Heart Association 8(21): e013151, October 2019.
O'Byrne ML, Millenson ME, Grady CB, Huang J, Bamat NA, Munson DA, Song L, Dori Y, Gillespie MJ, Rome JJ, Glatz AC: Trends in transcatheter and operative closure of patent ductus arteriosus in neonatal intensive care units: Analysis of data from the Pediatric Health Information Systems Database. American Heart Journal Page: doi.org/10.1016, 2019 Notes: e-published ahead of print.
2018
O'Byrne ML and Schidlow DN: Durable benefit of particle occlusion of systemic to pulmonary collaterals in select patients after superior cavopulmonary connection. Pediatr Cardiol 39(2): 245-253, Feb 2018.
O'Byrne ML, Kennedy KF, Rome JJ, Glatz AC: Variation in practice patterns in device closure of atrial septal defects and patent ductus arteriosus: An analysis of data from the IMproving Pediatric and Adult Congenital Treatment (IMPACT) registry. American Heart Journal 196: 119-130, February 2018.
O'Byrne ML, Scidlow DN: Durable Benefit of Particle Occlusion of Systemic to Pulmonary Collaterals in Select Patients After Superior Cavopulmonary Connection. Pediatric Cardiology 39(2): 245-253, February 2018.
O'Byrne ML, Kennedy KF, Berger JT, Kanter JP, Glatz AC: Risk factors for major early adverse events related to cardiac catheterization in children and young adults with pulmonary hypertension: An analysis of data from the Improving Adult and Congenital Treatment® (IMPACT®) Registry. Journal of the American Heart Association 7(5): e008142, Feb 2018.
Glatz AC, Kennedy KF, Rome JJ, O'Byrne ML: Variations in practice patterns and consistency with published guidelines for balloon aortic and pulmonary valvuloplasty: An analysis of data from the IMPACT® Registry. JACC Cardiovascular Intervention 1(6): 529-538, 2018.
O'Byrne ML, Glatz AC, Song L, Griffis HM, Millenson ME, Gillespie MJ, Dori Y, DeWitt AG, Mascio CE, and Rome JJ: Association between variation in preoperative care before arterial switch operation and outcomes in patients with transposition of the great arteries: An Analysis of Data from the Pediatric Health Information Systems Database. Circulation 138: 2119-2129, 2018.
O'Byrne ML, Kim S, Hornik CP, Yerokun BA, Matsouaka RA, Jacobs JP, Jacobs ML, Jonas RA: Effect of Obesity and Underweight Status on Perioperative Outcomes of Congenital Heart Operations in Children, Adolescents, and Young Adults: An Analysis of Data from the Society of Thoracic Surgeons Database. Circulation 136(8): 704-718, 2018.
2017
Jayaram N, Spertus JA, O'Byrne ML, Chan PS, Kennedy KF, Bergersen L, Glatz AC: Relationship between hospital procedure volume and complications following congenital cardiac catheterization: A report from the IMproving Pediatric and Adult Congenital Treatment (IMPACT) registry. American Heart Journal 183: 118-128, Jan 2017.
O'Byrne ML, Gillespie MJ, Kennedy KF, Dori Y, Rome JJ, Glatz AC: The influence of deficient retro-aortic rim on technical success and early adverse events following device closure of secundum atrial septal defects: An Analysis of the IMPACT Registry(®). Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 89(1): 102-111, Jan 2017.
O'Byrne ML, Desai S, Lane M, McBride M, Paridon S, Goldmuntz E: Relationship Between Habitual Exercise and Performance on Cardiopulmonary Exercise Testing Differs Between Children With Single and Biventricular Circulations. Pediatric Cardiology 38(3): 472-483, Mar 2017.
Goldberg DJ, Surrey LF, Glatz AC, Dodds K, O'Byrne ML, Lin HC, Fogel M, Rome JJ, Rand EB, Russo P, Rychik J: Hepatic Fibrosis is Universal Following Fontan Operation and Severity is Associated with Time from Surgery: A Liver Biopsy and Hemodynamic Study. Journal of the American Heart Association 6(5): e004809, April 2017.
Giaccone A, Zuppa AF, Sood Ba, Cohen MS, O'Byrne ML, Moorthy G, Mathur A, Kirpalani H: Milrinone Pharmacokinetics and Pharmacodynamics in Neonates with Persistent Pulmonary Hypertension of the Newborn. American Journal of Perinatology 34(8): 749-758, Jul 2017.
O'Byrne ML, Kim S, Hornik CP, Yerokun BA, Matsouaka RA, Jacobs JP, Jacobs ML, Jonas RA: Effect of Obesity and Underweight Status on Perioperative Outcomes of Congenital Heart Operations in Children, Adolescents, and Young Adults: An Analysis of Data From the Society of Thoracic Surgeons Database. Circulation 136(8): 704-718, August 2017.
O'Byrne ML, Shinohara RT, Grant EK, Kanter JP, Gillespie MJ, Dori Y, Rome JJ, Glatz AC: Increasing propensity to pursue operative closure of atrial septal defects following changes in the instructions for use of the Amplatzer Septal Occluder device: An observational study using data from the Pediatric Health Information Systems database. American Heart Journal 192: 85-97, October 2017.
Harahsheh AS, O'Byrne ML, Pastor B, Graham DA, Fulton DR: Pediatric Chest Pain-Low-Probability Referral. Clinical Pediatrics 56(13): 1201-1208, Nov 2017.
2016
Surrey LF, Russo P, Rychik J, Goldberg DJ, Dodds K, O’Byrne ML, et al. 2016. Prevalence and characterization of fibrosis in surveillance liver biopsies of patients with Fontan circulation. Human Pathology. 57:106-115.
O’Byrne ML, et al. 2016. Outcomes of patients with pulmonary atresia and major aortopulmonary collaterals without intervention in infancy. Pediatric Cardiology, 37(7): 1380-1391.
O’Byrne ML, et al. 2016. The Influence of Deficient Retro-Aortic Rim on Technical Success and Early Adverse Events Following Device Closure of Secundum Atrial Septal Defects: An Analysis of the IMPACT Registry ®. Catheterization Cardiovascular Intervention,37(7):1380-91.
Patel JK, O’Byrne M, et al. 2016. Diagnostic Electrophysiology Study Has Limited Value in Risk Stratification of Children and Young Adults With and Without Congenital Heart Disease. Journal of Innovations in Cardiac Rhythm Management. 7(2016):2257-2264.
O’Byrne ML, et al. 2016. Cost comparison of Transcatheter and Operative Pulmonary Valve Replacement (from the Pediatric Health Information Systems Database). American Journal of Cardiology, 117(1):121-126.
2015
O’Byrne ML, et al. 2015. Intra-procedural Bronchoscopy to Prevent Bronchial Compression During Pulmonary Artery Stent Angioplasty. Pediatric Cardiology, 37(3):433-441.
O’Byrne ML, et al. 2015. Predictors of catastrophic adverse outcomes in children with pulmonary hypertension undergoing cardiac catheterization. Journal of the American College of Cardiology, 66(11):1261-1269.
O’Byrne ML, et al. 2015. Effect of center catheterization volume on risk of catastrophic adverse event after cardiac catheterization in children. American Heart Journal, 169(6):823-832.
O’Byrne ML, et al. 2015. Cost-comparison of trans-catheter and operative closure of ostium secundum atrial septal defects. American Heart Journal, 169(5):727-735.
O’Byrne ML, et al. 2015. Middle-term results of trans-catheter creation of atrial communication in patients receiving mechanical circulatory support. Catheterization Cardiovascular Intervention, 85(7):1189-95.
O’Byrne ML, et al. 2015. Trends in Pulmonary Valve Replacement In Children and Adults with Tetralogy of Fallot. American Journal of Cardiology, 115(1):118-124.
O’Byrne ML, et al. 2015. Accuracy of transthoracic echocardiography in assessing retro-aortic rim prior to device closure of atrial septal defects. Congenital Heart Disease,10(4):E146-154.
2014
O'Byrne ML, Mercer-Rosa L, Zhao H, Zhang X, Yang W, Tanel RE, Marino BS, Cassedy A, Fogel MA, Rychik J, Paridon S, Goldmuntz E: Morbidity in children and adolescents after surgical correction of interrupted aortic arch. Pediatric Cardiology 35(3): 386-92, Mar 2014.
O'Byrne ML, Glatz AC, Sunderji S, Mathew AE, Goldberg DJ, Dori Y, Rome JJ, Gillespie MJ: Prevalence of deficient retro-aortic rim and its effects on outcomes in device closure of atrial septal defects. Pediatric Cardiology 35(7): 1181-90, Oct 2014.
O'Byrne ML, Yang W, Mercer-Rosa L, Parnell AS, Oster ME, Levenbrown Y, Tanel RE, Goldmuntz E: 22q11.2 Deletion syndrome is associated with increased perioperative events and more complicated postoperative course in infants undergoing infant operative correction of truncus arteriosus communis or interrupted aortic arch. The Journal of Thoracic and Cardiovascular Surgery 148(4): 1597-605, Oct 2014.
2013
O'Byrne ML, Mercer-Rosa L, Ingall E, McBride MG, Paridon S, Goldmuntz E: Habitual exercise correlates with exercise performance in patients with conotruncal abnormalities. Pediatric Cardiology 34(4): 853-60, Apr 2013.
O'Byrne ML, Mercer-Rosa L, Zhao H, Zhang X, Yang W, Cassedy A, Fogel MA, Rychik J, Tanel RE, Marino BS, Paridon S, Goldmuntz E: Morbidity in children and adolescents after surgical correction of truncus arteriosus communis. American Heart Journal 166(3): 512-8, Sep 2013.
Eckhauser AW, O'Byrne ML, Weinberg PM, Ravishankar C, Spray TL, Gaynor JW: Hypoplastic left ventricle and scimitar syndrome. The Annals of Thoracic Surgery 96(6): 2232-4, Dec 2013.
2011
Ofori-Amanfo G, Hsu D, Lamour JM, Mital S, O'Byrne ML, Smerling AJ, Chen JM, Mosca R, Addonizio LJ: Heart transplantation in children with markedly elevated pulmonary vascular resistance: impact of right ventricular failure on outcome. The Journal of Heart and Lung Transplantation : the official publication of the International Society for Heart Transplantation 30(6): 659-66, Jun 2011.
2008
Davies RR, Russo MJ, Hong KN, O'Byrne ML, Cork DP, Moskowitz AJ, Gelijns AC, Mital S, Mosca RS, Chen JM: The use of mechanical circulatory support as a bridge to transplantation in pediatric patients: an analysis of the United Network for Organ Sharing database. The Journal of Thoracic and Cardiovascular Surgery 135(2): 421-7, 427.e1, Feb 2008.
O'Byrne ML, Ognibene KM, Morris MC: Nesiritide in Treatment Refractory Pediatric Patients with Congestive Heart Failure. Clinical Intensive Care 17(4): 101-107, 2008.
2007
O'Byrne ML, Berman-Rosenzweig ES, Barst RJ: The effect of atrial septostomy on the concentration of brain-type natriuretic peptide in patients with idiopathic pulmonary arterial hypertension. Cardiology in the Young 17(5): 557-9, Oct 2007.
2002
Burrone J, O'Byrne M, Murthy VN: Multiple forms of synaptic plasticity triggered by selective suppression of activity in individual neurons. Nature 420: 414-418, November 2002.
Abstracts (includes Posters and Scientific Presentations)
2024
Edelson J, Huang J, Wang Z, Lefkowitz D, O'Connor MJ, White R, Wittlieb-Webber C, Rossano J, Lin K, Lane-Fall M, O'Byrne ML. : Identifying the Environmental Determinants of Health-Related Quality of Life in Children After Heart Transplant. International Society for Heart and Lung Transplantation Scientific Sessions. Prague Czech Republic April 2024 Notes: (format TBD).
Morrison J, Zedalis J, Parrish B, Goenaga EJ, Friedman D, Hawkins J, Shah F, Basu S, Ryan E, Tang J, Smith C, Callahan R, Gillespie MJ, Rome JJ, Hehir D, O'Byrne ML: Reducing Blood Product Waste in a Pediatric Cardiac Catheterization Laboratory- A Quality Improvement Initiative. Poster AHA Scientific Sessions, November 2024.
Morrison J, Zedalis J, Parrish B, Goenaga EJ, Friedman D, Hawkins J, Shah F, Basu S, Ryan E, Tang J, Smith C, Callahan R, Gillespie MJ, Rome JJ, Hehir D, O'Byrne ML.: Reducing Blood Product Waste in a Pediatric Cardiac Catheterization Laboratory- A Quality Improvement Initiative. (poster). AHA Scientific Sessions Chicago IL November 2024.
2023
Wong-Seigel JR, Glatz AC, McCracken C, Lee C, Veiga LHS, Kitahara CM, Goldstein BH, Petit CJ, Qureshi AM, Nicholson GT, Law MA, Meadows J, Shahanavaz S, O'Byrne ML, Batlivala SP, Beshish A, Mascio CE, Romano CE, Romano JC, Stack KO, Asztalos I, Zampi JD: Cumulative Radiation Exposure in Neonates With Symptomatic Tetralogy of Fallot Requiring Early Intervention (poster). 2023 American College of Cardiology Scientific Sessions, Washington, DC March 2023.
Lai KC, Richardson T, Berman D, DeMauro SB, King BC, Lagatta J, Lee HC, Lewis T, Noori S, O'Byrne ML, Patel RM, Slaughter J, Lakshmanan A: Current Trends in Invasive Closure of Patent Ductus Arteriosus in Very Low Birth Weight Infants (oral abstract) Pediatric Academic Societies Meeting, Washington DC May 2023.
Vega TF, Huber M, O'Byrne ML, Gibbs K, Frank DB, Avitabile C, Lorch SA, Jensen E, Bamat NA: Pulmonary Vasodilator Use In Very Preterm Infants Admitted to United States Children's Hospitals (poster). 2023 Pediatric Academic Societies Meeting, Washington D.C May 2023.
Weinreb SJ, Huang YS, Vetter VL, Iyer VR, Srinivasan C, Shah MJ, O'Byrne ML, Janson CM: Contemporary Outcomes in Neonates with Isolated Congenital Complete Heartblock- An Analysis of the PHIS Database (poster). Heart Rhythm Society Meeting. New Orleans, LA May 2023.
Barack-Corren Y, Herz C, Lasso Andras, Dori Y, Tang J, Smith CL, Callahan R, Rome JJ, Gillespie MJ, Jolley M, O'Byrne ML.: Developing a Novel Method for Measuring Relative Lung Perfusion at the Catheterization Laboratory. (Poster Presentation). American Heart Association Scientific Sessions, Philadelphia, PA November 2023.
Hakimi M, Mondal A, Ampah S, O'Byrne ML, Janson C. : Admission Rates for Pediatric Supraventricular Tachycardia From the Emergency Department Are Affected by Primary Insurance Payor: An Analysis of the NEDS Database. (Poster Presentation). American Heart Association Scientific Sessions, Philadelphia, PA November 2023.
Nunez Gallegos F, Maskatia SA, Zampi J, Nicholson G, McCracken C, Mascio CE, Petit CJ, Romano J, Zanaboni D, O'Byrne ML, Nanduri A, Wong-Siegel J, Law MA, Hock KM, Shahanavaz S, Batlivala SP, Speed S, Meadows JJ, Qureshi AM, Taleb M, Khan H,, Liggon A Glatz AC, Lopez KN. : Driving Distance to a Primary Cardiac Center is Associated With Mortality in Patients with Tetralogy of Fallot Undergoing Neonatal Interventions. American Heart Association Scientific Sessions, Philadelphia, PA. November 2023 Notes: Poster
Trucco SM, McCracken C, Glatz AC, Petit CJ, Qureshi AM, Shahanavaz S, Nicholson G, Abejero N, Ligon A, Patel J, Mascio CE, Maskatia SA, Romano J, O'Byrne ML, Stack K, Wong-Siegel J, Beshish A, Law M, Hock K, Batlivala SP, Speed S, Meadows JJ, Goel D, Khan H, Goldstein BH: Timing and Mode of Death Following Treatment of Neonatal Symptomatic Tetralogy of Fallot. American Heart Association Scientific Sessions November 2023 Notes: (poster).
Vaiyani D, Ford B, Gupta M, Dietzman T, Biko D, Dewitt AG, Gillespie MJ, O'Byrne ML, Rome JJ, Smith CL, Dori Y: Lymphatic Intervention Following Superior Cavo-Pulmonary Anastomosis Potentially allows for successful Fontan Completion ( Poster Presentation) American Heart Association Scientific Sessions, Philadelphia, PA. November 2023.
2022
Berger JH, Faerber JA, Okunowo O, O'Connor MJ, O'Byrne ML, Lin KY: Clinical Practice Variation of Statin Use in Pediatric Heart Transplantation (oral abstract). International Society for Heart and Lung Transplant, Denver CO April 2022.
Nash D, Shah MJ, Srinivasan C, Iyer VR, *O'Byrne ML, Janson CM: Association of Center Ablation Volume and Procedural Outcomes in Children: An Analysis of the IMPACT® Registry (oral abstract) Heart Rhythm Society, San Francisco, CA April 2022 Notes: *co-senior authors.
Gupta M, Pinter C, Cianciulli A, Dewey H, Silvani A, Lasso A, O'Byrne ML, Glatz AC, Jolley M: Development of a 3D Modeling Tool for Procedural Planning of Ductal Stenting (featured oral abstract) Society for Cardiac Angiography and Intervention Scientific Sessions, Atlanta GA May 2022
49. Lemley BA, Wu L, Roberts AL, Shinohara RT, Smith CL, Dori Y, Rome JJ, Gillespie MJ, Glatz AC, O'Byrne ML: Trends in Ductal Arteriosus Stent Versus Blalock-Thomas-Taussig Shunt Utilization in Neonates With Ductal-Dependent Pulmonary Blood Flow (poster). American Heart Association QCOR meeting, Reston VA May 2022.
Crilly CJ, Sharma P, Tam V, Smith CL, Tang J, Dori Y, Gillespie MJ, Glatz AC, O'Byrne ML: Examining the association between social determinants of health and health-related quality of life among children with cardiac conditions. American Heart Association Scientific Sessions, Chicago IL November 2022.
Edelson J, Lane-Fall M, Huang J, Wang Z, Mercer-Rosa LM, Mitchell J, Paridon S, O'Connor MJ, Rossano J, O'Byrne ML: Neighborhood childhood opportunity index is associated with impaired exercise performance in pediatric heart transplant patients (moderated digital poster). American Heart Association Scientific Sessions, Chicago IL November 2022.
Lemley B, Shinohara R, Okunowo O, Ampah S, Goldberg D, Rychik J, Glatz AC, Amaral S, O'Byrne ML: Association of patient characteristics and center on age of fontan completion: A retrospective cohort study using the Pediatric Health Information Systems database (poster). American Heart Association Scientific Sessions, Chicago IL November 2022.
O'Byrne ML, Song L, Huang J, Lemley B, Smith, Smith CL, Tang J, Dori Y, Gillespie MJ, Goldberg D, Gardner M, Ravishankar C, Rome JJ, Glatz AC: Attributable mortality benefit of digoxin treatment in hypoplastic left heart syndrome after the Norwood operation (rapid fire oral abstract). American Heart Association Scientific Sessions, Chicago IL November 2022.
Rastogi R, Okunowo O, Faerber J, Mavroudis CD, Giglia TG, Witmer C, Raffini L, O'Byrne ML: Incidence, management, and outcomes of pediatric pulmonary embolism in the United States: An observational study using data from the Pediatric Health Information Systems database (rapid fire oral abstract). American Heart Association Scientific Sessions, Chicago IL November 2022.
Lectures by Invitation
2025
O'Byrne M. "Interventional Cardiology Trials" CHOP Cardiology 2025, Orlando FL. Feb 2025.
2024
O'Byrne M. "Leveraging Pediatric/Congenital Cardiology Registries to Improve Outcomes", Niland Invited Lectureship/Pediatric Grand Rounds, Mott Children's Hospital and University of Michigan, Ann Arbor MI. Jun 2024.
O'Byrne M. "Digoxin Use in Single Ventricle", CHOP Cardiology 2024, Scottsdale AZ. Feb 2024.
2023
O'Byrne M. "New Transcatheter Pulmonary Valve. American Academy of Pediatrics National Conference and Exhibition", Washington, D.C. Oct 2023.
O'Byrne M. "Changes in Practice/Outcomes of Pediatric/Congenital Catheterization in Response to the First Wave of COVID", C3PO Research and Publications Committee Webinar. Delivered remotely. Mar 2023.
O'Byrne M. "Data infrastructure supports research and quality improvement efforts", C3PO Quality Improvement Webinar. Delivered remotely. Feb 2023.
Editorials, Reviews, Chapters
2024
O'Byrne ML: The ABC's of leveraging APCD for research in congenital cardiology, Circ CV Quality and Outcomes 17(9), 2024 Notes: e011359.
2023
O'Byrne ML: Patient-Reported Outcomes in Tetralogy of Fallot: The Potential of the CORRELATE Cohort. JAmCollCardiol 81(19): 1951-1953, May 2023.
O'Byrne ML: Commentary on: "Broad- vs. narrow-spectrum perioperative antibiotics and outcomes in pediatric heart disease surgery: Analysis of the Vizient Clinical Data Base. J Ped Infect Dis Soc 12(6): 319-321, June 2023.
Rome JJ and O'Byrne ML: Hybrid Palliation for Critical Left Heart Obstruction is Versatile: Risk Factors Still Impede Outcome. JAmCollCardiol 82(14): 1442-1444, 2023.
2022
Yeh MJ, Bergersen L, Gauvreau K, Barry OM, Batlivala SP, Bjornlund E, Boe B, Caneo LF, Croti UA, Doyle T, Furnaz S, Moraes RC, O'Byrne ML, de Olivaera Paes E, Palacios-Macedo A, Pechilkov D, Sandoval NF, Sen S, Stajevic M, Ferreira Travessa MA, Jenkins KJ: COVID-19 international experience in paediatric patients with congenital heart disease. Heart 15: 1-8, Sep 2022 Notes: E-published ahead of print.
Byfield, R, O'Byrne ML and Collins RT: Hypertension. Netter Pediatrics Tenney-Soeiro R and Pete Devon E (eds.). 2nd Ed: 604-609. 2022.
Tomasulo CE, Rogers LS, Andrade L, O'Byrne ML: Transcatheter Device Closure of a Perimembranous Ventricular Septal Defect in Congenitally Corrected Transposition of the Great Arteries. Cong Heart Dis Page: DOI 10.32604, Dec 2022 Notes: in press.
2020
O'Byrne ML, Peyvandi S.: Decisions, Decisions, Decisions…: A Novel Approach Helps Evaluate Potential Benefit of Fetal Aortic Valvuloplasty. Circ Cardiovasc Qual Outcomes 13: e006636, Apr 2020.
Smith CL, Saul D, Goldfarb SB, Biko DM, O'Byrne ML: Compression of the left mainstem bronchus by patent ductus arteriosus in neonates under consideration for ductal stenting. Catheter Cardiovasc Intervent 95: 1158-1162, May 2020.
O'Byrne ML, Smith CL, Gillespie MJ.: Device Closure of Patent Ductus Arteriosus in Adults. Can J Cardiol 36: 795-796, June 2020.
O'Byrne ML and Peyvandi S: Decisions, Decisions, Decisions...: A Novel Approach Helps Evaluate Potential Benefit of Fetal Aortic Valvuloplasty. Circ Cardiovasc Qual Outcomes 13(4): e0006636, 2020.
2019
O'Byrne ML, Smith CE, Gillespie MJ: Device closure of patent ductus arteriosus in adults. Canadian Journal of Cardiology 36(6): 795-796, May 2019 Notes: Invited editorial.
O'Byrne ML: Expert Analysis: The Goldilocks Dilemma in Pediatric Heart Disease: Neither Too Big Nor Too Small. ACC.com June 2019 Notes: Invited narrative review.
2018
O'Byrne ML, Cross RR, Martin GR: Asymptomatic atresia of the anomalous pulmonary vein in a patient with scimitar syndrome presenting in childhood. Cardiology in the Young 28(2): 329-333, February 2018 Notes: Case report. PMCID: 6112172
O'Byrne ML, Jacobs JP, Jacobs ML, Jonas RA: Response by O'Byrne et al to Letter Regarding Article, "Effect of Obesity and Underweight Status on Perioperative Outcomes of Congenital Heart Operations in Children, Adolescents, and Young Adults: An Analysis of Data From the Society of Thoracic Surgeons Database". Circulation 137(7): 759, February 2018 Notes: Invited response to letter.
2017
O'Byrne ML, Rome JJ: Assessment of heart failure by invasive methods. Heart Failure in the Child and Young Adult: From Bench to Bedside 2017 Notes: book chapter.
2016
O’Byrne ML, Gillespie MJ. Melody Valve and Transcatheter Pulmonary Valve Replacement. In: Ailawadi G and Kron IL, editors. Catheter Based Valvular and Aortic Surgery. New York: Springer; 2016. p. 266-282.
2012
O’Byrne ML, Shaddy RE. 2012. Pediatric heart failure and adult congenital heart disease. Advances in Heart Failure Management. 116-127
2011
O’Byrne ML, Collins RT. Hypertension. In: Florin TA, Ludwig SL, editors. Netter Pediatrics. Philadelphia: Saunders; 2011. Chapter 47, p. 289-293.
O’Byrne ML, John A. Cyanotic Heart Disease. In: Florin TA, Ludwig SL, editors. Netter Pediatrics. Philadelphia: Saunders; 2011. Chapter 44, p. 269-277.