MD - Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
PhD in Immunology - Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Pediatrics - Children's Hospital of Philadelphia, Philadelphia, PA
Fellow
Isenberg SL, Carter MD, Moon JL, Laughlin S, Petway M, Mojica MA, Rood JE, Gursky AK, Sheppard CI, Bagarozzi DA, Pirkle JL, Johnson RC. The Effects of Gamma Irradiation on Chemical Biomarker Recovery from Mixed Chemical/Biological Threat Exposure Specimens. J Appl Lab Med. 2020 Mar 1;5(2):273-280. doi: 10.1093/jalm/jfz022. PMID: 32445395
Flynn RS, Hill ME, Rood JE, Parga JJ. Abnormal Eye Movements and Poor Feeding in an Infant. Clin Pediatr (Phila). 2020 May;59(4-5):532-535. doi: 10.1177/0009922819901013. Epub 2020 Jan 23. PMID: 31971002
Burn TN, Weaver L, Rood JE, Chu N, Bodansky A, Kreiger PA, Behrens EM. Genetic Deficiency of Interferon-γ Reveals Interferon-γ-Independent Manifestations of Murine Hemophagocytic Lymphohistiocytosis. Arthritis Rheumatol. 2020 Feb;72(2):335-347. doi: 10.1002/art.41076. Epub 2019 Dec 15. PMID: 31400073
Isenberg SL, Carter MD, Moon JL, Laughlin S, Petway M, Mojica MA, Rood JE, Gursky AK, Sheppard CI, Bagarozzi DA, Pirkle JL, Johnson RC. The Effects of Gamma Irradiation on Chemical Biomarker Recovery from Mixed Chemical/Biological Threat Exposure Specimens. J Appl Lab Med. 2020 Mar 1;5(2):273-280. doi: 10.1093/jalm/jfz022. PMID: 32445395
Flynn RS, Hill ME, Rood JE, Parga JJ. Abnormal Eye Movements and Poor Feeding in an Infant. Clin Pediatr (Phila). 2020 May;59(4-5):532-535. doi: 10.1177/0009922819901013. Epub 2020 Jan 23. PMID: 31971002
Burn TN, Weaver L, Rood JE, Chu N, Bodansky A, Kreiger PA, Behrens EM. Genetic Deficiency of Interferon-γ Reveals Interferon-γ-Independent Manifestations of Murine Hemophagocytic Lymphohistiocytosis. Arthritis Rheumatol. 2020 Feb;72(2):335-347. doi: 10.1002/art.41076. Epub 2019 Dec 15. PMID: 31400073
Patamawenu AA, Wright NE, Shofner T, Evans S, Manion MM, Doria-Rose N, Migueles SA, Mendoza D, Peterson B, Wilhelm C, Rood J, Berkley A, Cogliano NA, Liang CJ, Tesselaar K, Miedema F, Bess J Jr, Lifson J, Connors M. Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells. PLoS One. 2019 Dec 12;14(12):e0225806. doi: 10.1371/journal.pone.0225806. eCollection 2019. PMID: 31830058
Avetisyan M, Rood JE, Lopez SH, Sengupta R, Wright-Jin E, Dougherty J, Behrens EM, Heuckeroth RO. Muscularis macrophage development in the absence of an enteric nervous system. Proceedings of the National Academy of Sciences of the United States of America. 2018, May; 115(18): 4696-4701. Cited in PubMed; PMID: 29666241. Pub Status: Published.
Rood JE, Burn TN, Neal V, Chu N, Behrens EM.. Disruption of IL-33 Signaling Limits Early CD8+ T Cell Effector Function Leading to Exhaustion in Murine Hemophagocytic Lymphohistiocytosis. Frontiers in Immunology. 2018, Nov; 9(N/A): 2642. Cited in PubMed; PMID: 30515155. Pub Status: Published.
Rood JE, Canna SW, Weaver LK, Tobias JW, Behrens EM. IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation. Journal of Leukocyte Biology. 2017, Apr; 101(4): 1037-1044. Cited in PubMed; PMID: 28034913. Pub Status: Published.
Rood JE, Rao S, Paessler M, Kreiger PA, Chu N, Stelekati E, Wherry EJ, Behrens EM. ST2 contributes to T cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice. Blood. 2016, Jan; 127(4): 426-435. Cited in PubMed; PMID: 26518437. Pub Status: Published.
Mendoza D, Migueles SA, Rood JE, Peterson B, Johnson S, Doria-Rose N, Schneider D, Rakasz E, Trivett MT, Trubey CM, Coalter V, Hallahan CW, Watkins D, Franchini G, Lifson JD, Connors M. Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques. PLoS Pathogens. 2013, Feb; 9(2): e1003195. Cited in PubMed; PMID: 23468632. Pub Status: Published.
Migueles SA, Rood JE, Berkley AM, Guo T, Mendoza D, Patamawenu A, Hallahan CW, Cogliano NA, Frahm N, Duerr A, McElrath MJ, Connors M. Trivalent adenovirus type 5 HIV recombinant vaccine primes for modest cytotoxic capacity that is greatest in humans with protective HLA class I alleles. PLoS Pathogens. 2011, Feb; 7(2): e1002002. Cited in PubMed; PMID: 21383976. Pub Status: Published.
Migueles SA, Weeks KA, Nou E, Berkley AM, Rood JE, Osborne CM, Hallahan CW, Cogliano-Shutta NA, Metcalf JA, McLaughlin M, Kwan R, Mican JM, Davey RT Jr, Connors M. Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy. J Virol. 2009 Nov;83(22):11876-89. doi: 10.1128/JVI.01153-09. Epub 2009 Sep 2. PMID: 19726501
Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, Rood JE, Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G, Kwan R, McLaughlin M, Stallings S, Rehm C, O'Shea MA, Mican J, Packard BZ, Komoriya A, Palmer S, Wiegand AP, Maldarelli F, Coffin JM, Mellors JW, Hallahan CW, Follman DA, Connors M. Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity. 2008 Dec 19;29(6):1009-21. doi: 10.1016/j.immuni.2008.10.010. Epub 2008 Dec 8. PMID: 19062316
2016, Children’s Hospital of Philadelphia Research Poster Day Award
2016, George W. Householder III Memorial Prize, Perelman School of Medicine
2016, Keystone Symposia Future of Science Scholarship
2015-2017, T32 Training Grant in Rheumatic Diseases, Predoctoral Trainee
2015, UPenn Immunology Graduate Group Retreat Poster Presentation Award
2014, UPenn Immunology Graduate Group Retreat Oral Presentation Award
2014, Rheumatology Research Foundation Student Achievement Award
2009, AIDS Vaccine Conference International Scholarship Recipient