Eduardo Ruchelli, MD

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Eduardo Ruchelli, MD, is an attending pathologist who works with the Congenital Hyperinsulinism Center and the Division of Anatomic Pathology at Children's Hospital of Philadelphia.

Areas of Expertise: Fetal and perinatal pathology, Pathologic evaluation of the pancreas in congenital hyperinsulinism, Pediatric liver and gastrointestinal diseases
Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - University of Buenos Aires School of Medicine, Argentina


Hospital of the Medical College of Pennsylvania, Philadelphia, PA


Children's Hospital of Pittsburgh, Pittsburgh, PA


Magee-Women's Hospital, Pittsburgh, PA

Board Certification

Anatomic and Clinical Pathology – American Board of Pathology
Pediatric Pathology – American Board of Pathology

Titles and Academic Titles

Attending Pathologist

Director, Pediatric Pathology Fellowship Program

Departments and Services

Research Interests

Congenital hyperinsulinism
Eosinophilic esophagitis




Ernst L, Grossman A, Ruchelli E. Familial Perinatal Liver Disease and Fetal Thrombotic Vasculopathy. Pediatr Dev Pathol 2008;11:160-163.

Spinner NB, Saitta SC, Delaney DP, Colliton R, Zderic SA, Ruchelli E, Zackai E, Kolon T. Intracytoplasmic sperm injection (ICSI) with transmission of a Ring Y chromosome and ovotesticular disorder of sex development in offspring. Am J Med Genet 2008;146A:1828-31.

Danzer E, Davey MG, Kreiger PA, Ruchelli ED, Johnson MP, Adzick NS, Flake AW, Hedrick HL. Fetal Tracheal Occlusion for Severe Congenital Diaphragmatic Hernia in Humans: A Morphometric Study of Lung Parenchyma and Muscularization of Pulmonary Arterioles. J Pediatr Surg 2008; 43:1767–1775.


Hardy OT, Hernandez-Pampaloni M, Saffer JR, Suchi M, Ruchelli E, Zhuang H, Ganguly A, Freifelder R, Adzick NS, Alavi A, Stanley CA.. Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa PET scan. J Pediatr 2007;150:140-5.

Liacouras CA, Bonis P, Putnam PE, Straumann A, Ruchelli E, Gupta SK, Lee JJ, Hogan SP, Wershil BK, Rothenberg ME, Ackerman SJ, Gomes I, Murch S, Mishra A, Furuta GT. Summary of the First International Gastrointestinal Eosinophil Research Symposium. J Pediatr Gastroenterol Nutr 2007;45:370-91.

Davey M, Shegu S, Danzer E, Ruchelli E, Adzick S, Flake A, Hedrick HL. Pulmonary arteriole muscularization in lambs with diaphragmatic hernia after combined tracheal occlusion/glucocorticoid therapy. Am J Obstet Gynecol 2007;197:381.


Suchi M, MacMullen C, Thornton PS, Adzick NS, Ganguly A, Ruchelli ED, Stanley CA. Molecular and Immunohistochemical Analyses of the Focal Form of Congenital Hyperinsulinism. Mod Pathol 2006;1:122-9

Liechty KW, Hedrick HL, Hubbard AM, Johnson MP, Wilson RD, Ruchelli ED, Howell LJ, Crombleholme TM, Flake AW, Adzick NS. Severe pulmonary hypoplasia associated with giant cervical teratomas. J Pediatr Surg 2006;41:230-3.

Kreiger PA, Ruchelli ED, Mahboubi S, Hedrick H, Adzick NS, Russo PA. Fetal pulmonary malformations: defining histopathology. Am J Surg Pathol. 2006;30:643-9.

Iyoob SD, Tsai A, Ruchelli ED, Coleman BG, Wilson RD. Large umbilical cord hemangioma: sonographic features with surgical pathologic correlation. J Ultrasound Med. 2006;25:1495-8.


Liacouras CA, Spergel JM, Ruchelli E, Verma R, Mascarenhas M, Semeao E, Flick J, Kelly J, Brown-Whitehorn T, Mamula P, Markowitz J. Eosinophilic Esophagitis: A 10 year experience in 381 children. Clin Gastroenterol Hepatol  2005;3:1198-1206


Adzick NS, Thornton PS, Stanley CA, Kaye R, Ruchelli E. A multidisciplinary approach to the focal form of congenital hyperinsulinism leads to successful treatment by partial pancreatectomy. J Pediatr Surg 2004;39:270-5

Suchi M, Thornton PS, Adzick NS, MacMullen C, Ganguly A, Stanley CA, Ruchelli ED. Congenital hyperinsulinism: intraoperative biopsy interpretation can direct the extent of pancreatectomy. Am J Surg Pathol 2004;28:1326-1335

Liacouras CA, Ruchelli E. Eosinophilic esophagitis. Curr Opin Pediatr 2004;16:560-566 


Fogg MI, Ruchelli E, Spergel JM. Pollen and eosinophilic esophagitis. J Allergy Clin Immunol 2003; 112:796-7