Skip to main content

Congenital Hyperinsulinism Center

Children with a congenital hyperinsulinism (HI) diagnosis — or with persistent low blood glucose levels — receive expert evaluation, diagnosis, treatment and follow-up care at the Congenital Hyperinsulinism Center at Children's Hospital of Philadelphia (CHOP).

We have cared for children from 49 states and 20 countries. Our team offers comprehensive support through the process of referring and transporting patients with HI to CHOP.

For more than 50 years, our HI experts have been at the forefront of advances in HI diagnosis and treatment. Our team has deep knowledge of the various types of HI and how to manage them to keep your child safe from the dangerous effects of hypoglycemia.

Because so few adult endocrinologists are familiar with HI, we also offer care to adults with HI.

CHOP's Congenital Hyperinsulinism Center is recognized as a Center of Excellence by Congenital Hyperinsulinism International.

How we serve you

The type of hyperinsulinism your child has guides treatment, including a potential cure. Some children's HI requires long-term medical management that changes over time. We also care for children whose HI is an accompanying symptom of another syndrome.

Conditions we treat

Congenital HI is so rare that only 1 in 25,000 to 50,000 children are diagnosed with HI. Our experts also treat children with other disorders resulting in persistent low blood glucose (also called hypoglycemia).

View fewer conditions View all conditions
young girl standing with hands on hips smiling

Why choose CHOP for HI treatment

Experience counts. Most children’s hospitals only see one or two HI cases a year. CHOP has treated more than 1,900 children with congenital HI, making us the world's most active Congenital Hyperinsulinism Center.