Matthew J. Ryan, MD
Matthew J. Ryan, MD

Matthew J. Ryan, MD

Matthew J. Ryan, MD, is a pediatric gastroenterologist at Children's Hospital of Philadelphia with a special interest in liver disease and bile duct development.

Areas of expertise: Airway complications related to GERD, Functional abdominal pain, Primary Sclerosing cholangitis, Transnasal endoscopy

Locations: Specialty Care & Surgery Center, Voorhees, Specialty Care, Atlantic County

Make an appointment

215-590-3630

1-866-KID-LIVR (1-866-543-5487)

About Matthew J. Ryan, MD

Titles

Attending Physician

Associate Professor of Clinical Pediatrics (Gastroenterology, Hepatology and Nutrition), Perelman School of Medicine at the University of Pennsylvania

Certifications

Pediatric Gastroenterology – American Board of Pediatrics

Pediatrics – American Board of Pediatrics

Awards and Honors

2015-2018, Fellow's Teaching Award Honor Roll
2006-2008, CDHNF Young Investigator's Development Award
2006, 2nd place Komorov Competition-basic science
2004-2006, NIH Loan Repayment Program

Leadership and Memberships

Memberships in professional organization

International

2003-present, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition
- 2015-present, Ethics Committee

National

2007-present, American Association for the Study of Liver Diseases
2003-present, The American Gastroenterology Association
2000-present, American Academy of Pediatrics

Editorial and Academic Positions

Editorial positions

2011, Journal of Clinical Investigation, Ad hoc reviewer
2010, Human Immunology, Ad hoc reviewer

Academic and institutional committees

2015-present, Chair of the GI ACGME program evaluation committee - PEC
2011-present, Division of GI, Hepatology and Nutrition Second Opinion Committee

Research Interests

Pediatric liver disease Bile duct development Growth and remodeling Notch signaling

Education & training

Medical Degree

MD - University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ

Internship

Pediatrics - The University of Chicago Children's Hospital, Chicago, IL

Residency

Pediatrics - The University of Chicago Children's Hospital, Chicago, IL

Fellowship

Pediatric Gastroenterology - The Children's Hospital of Philadelphia, Philadelphia, PA
Research Fellow, Pediatric Gastroenterology - The Children's Hospital of Philadelphia, Philadelphia, PA

Team affiliations

 View fewer all team affiliations View all all team affiliations

Publications

Publications

2021

Aileen Wertz, Matthew Ryan, Ian Jacobs, Joseph Piccione: Impact of Pre-operative Multidisciplinary Evaluation on Laryngotracheal Reconstruction Outcomes. The Laryngoscope 131(7): E2356-E2362, July 2021.

2014

Underkoffler LA, Carr E, Nelson A, Ryan MJ, Schultz R, Loomes KM: Microarray data reveal relationship between Jag1 and Ddr1 in mouse liver. PLoS One 9(1), Jan 2014 Notes: doi: 10.1371/journal.pone.0084383. eCollection

2008

Ryan Matthew J, Bales Christina, Nelson Anthony, Gonzalez Dorian M, Underkoffler Lara, Segalov Michelle, Wilson-Rawls Jeanne, Cole Susan E, Moran Jennifer L, Russo Pierre, Spinner Nancy B, Kusumi Kenro, Loomes Kathleen M: Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype. Hepatology (Baltimore, Md.) 48(6): 1989-97, Dec 2008.

2007

Loomes KM, Russo P, Ryan M, Nelson A, Underkoffler L, Glover C, Hong F, Thomas G, Kaestner K, Oakley R.: Bile Duct Proliferation in Liver Specific Jag Conditional Knockout Mice: Effects of Gene Dosage. Hepatology 45(2): 323-30, January 2007.

Loomes, Kathleen M.  Stevens, Stacey A.  O'Brien, Megan L.  Gonzalez, Dorian M.  Ryan, Matthew J.  Segalov, Michelle.  Dormans, Nicholas J.  Mimoto, Mizuho S.  Gibson, Joshua D.  Sewell, William.  Schaffer, Alyssa A.  Nah, Hyun-Duck.  Rappaport, Eric F.  Pratt, Stephen C.  Dunwoodie, Sally L.  Kusumi, Kenro.: Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects. Developmental Dynamics 236(10): 2943-51, Oct 2007.

Lectures by Invitation
2023

Ryan M. "The ABCs or LFTs" CHOP Nursing lecture, Philadelphia,PA. Oct 2023.

Ryan M. "CHOP Experience with Unsedated Transnasal Endoscopy" EvoEndo Board, Boston. Sept 2023.

Ryan M. "Functional Abdominal Pain" CHOP Harborview Pediatrics. Sept 2023.

Ryan M. "What Goes Down, Sometimes Comes Up", Chester County Hospital. Sept 2023.

2022

Ryan M. GERD in the NICU, Virtu Hospital, Voorhees - Virtual conference. Mar 2022.

2021

Ryan M. To Thicken or Not To Thicken, NASPGHAN Single Topic Symposium, Virtual. Nov 2021.

Editorials, Reviews, Chapters
2008

Ryan JM: Vomiting, Splenomegaly and Asplenia/Hyposplenia. The Five Minute Pediatric Consult, 5th edition. Lippincott Williams and Wilkins, 2008.

Patient experience rating

(based on 154 submissions)
  • Clear Explanation
    4.9 of 5
  • Showed Concern
    4.9 of 5
  • Would recommend
    4.9 of 5
  • Discussion of Proposed Treatment
    4.9 of 5
Learn about the patient experience rating system

Comments

  • The doctor is amazing! So friendly and showed empathy to my concerns and helped come up with a plan going forward! Would definitely recommend!!
    5 of 5
    Mar 27, 2025

  • We love dr Ryan and staff always great!
    5 of 5
    Mar 27, 2025

  • Dr Ryan is the first doctor who made my child feel like we could find some solutions for her varous symptoms.
    5 of 5
    Feb 23, 2025

  • Again, Dr. Ryan is great.
    5 of 5
    Feb 06, 2025

  • We've seen Dr. Ryan for almost 5 years now. He manages my son's condition with care and empathy. He takes time to ask my son what he's interested in and know him beyond his illness. Dr. Ryan makes suggestions and then asks for our input. I really feel like values us parents as partners.
    5 of 5
    Dec 28, 2024

  • Dr. Ryan asked many questions about the concerns we had about our daughters GI concerns. He explained what he thought the next steps should be and we agreed. (To keep doing what we are doing which is to avoid foods that cause a reaction in our daughter)
    5 of 5
    Dec 26, 2024

  • Dr. Ryan to explain all possible diagnosises and options for testing. He was understanding and agreeable when I suggested things. He spoke to me like a person and not just another patient Mom.
    5 of 5
    Dec 26, 2024

  • The doctor was very kind and personable, listened well, gave detailed information, and talked us through all of his thoughts and steps. I'm very impressed with his attention and detail.b
    4.8 of 5
    Dec 26, 2024

  • Dr. Ryan is the best he is always attentive and informative and helps us feel at ease
    5 of 5
    Nov 29, 2024

  • Dr Ryan is excellent!
    5 of 5
    Oct 25, 2024

  • Dr. Ryan was amazing with my son. He was so caring and educated, felt much better when we left .
    5 of 5
    Oct 08, 2024

  • Dr.Ryan is truly is a wonderful doctor he is so kind and helping with my son's needs
    5 of 5
    Oct 01, 2024

  • Dr Ryan is an amazing doctor. He was always excellent with all of my children
    5 of 5
    Sep 14, 2024

  • Dr Ryan is awesome!
    5 of 5
    Aug 12, 2024

  • He is an professional, he demonstrates care for his patients and provides all information I need to make sure my child gets well.
    5 of 5
    Jul 26, 2024

  • CHOP doctors are AMAZING! They have the experience and knowledge like none other! Thank you Dr.Ryan
    5 of 5
    Jun 28, 2024

  • Dr. Ryan is simply an exceptional physician!
    5 of 5
    May 23, 2024

  • Dr. Ryan is caring, thorough, and very knowledgeable. He is the best!!
    5 of 5
    May 12, 2024

  • We absolutely loved our experience with the doctor. He really took the time to listen carefully, didn't rush us, and discussed possible options. He was cordial and light hearted. Both mom and child left the visit very happy.
    5 of 5
    Apr 19, 2024

  • Excellent care. Dr Ryan answers all our questions, always taking time hear our concerns.
    5 of 5
    Apr 07, 2024

  • Was very impressed with the doctors professionalism and knowledge
    5 of 5
    Apr 02, 2024

  • Dr. Ryan was wonderful in communicating with me and our daughter, who has difficulty communicating due to being on the autism spectrum. Dr. Ryan shared helpful information with us and gave our child treatment that has already helped. We got very lucky when we found Dr. Ryan!
    5 of 5
    Mar 09, 2024

  • It was nice not to have to repeat the entire story of why we were there to Dr. Ryan. He came in familiar with our case eventhough it was our first visit. You could tell he took the time to read the chart and make sure he came in to the visit informed and ready to brainstorm solutions
    4.4 of 5
    Feb 22, 2024

  • Dr Ryan goes above and beyond for his patients. He cares about the patient and focuses on whole body rather than just the "GI"
    5 of 5
    Feb 08, 2024

  • Dr. Ryan was very personable. He was a wealth of information. He was an absolute pleasure understanding and addressing all of ours concerns and questions.
    5 of 5
    Feb 06, 2024

  • Dr. Ryan actually took the time to learn my childs medical history and chose to treat my child as an individual based on his needs vs being treated generically. My childs medical history and on going care was considered carefully and discussed by Dr ryan
    5 of 5
    Jan 28, 2024

  • Loved Dr. Ryan
    5 of 5
    Jan 20, 2024

  • Dr. Ryan was truly amazing! He spent a lot of time with us to help figure out what was going on with my daughter. He explained it with ease and he included us in trying to figure it out. He spoke on our level and not over our heads. We wish all doctors were like him.
    5 of 5
    Dec 21, 2023

  • Dr Ryan was very attentive. He addressed my concerns about my son right away and even emailed the feeding team during our visit and we got the reponse back during the visit.
    5 of 5
    Dec 01, 2023

  • Dr Ryan is wonderful to work with. He applies his expert knowledge to our problem with concern and special attention for our specific needs and requests. I would highly recommend him to anyone who needs a G.I. specialist.
    5 of 5
    Nov 14, 2023
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About the Patient Experience Rating System

The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. We are committed to true transparency. However, to ensure the comments are fair and correctly attributed, we review each one before posting to the website. We exclude entire comments that disclose patient’s protected health information, are off-topic, or include other confidential or inappropriate content. Comments will appear on provider bios only if providers have a minimum number of comments. Comments are shared internally for education purposes to ensure that we are doing our very best for the patients and families for whom we are privileged to care. The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.