Matthew J. Ryan, MD

Matthew J. Ryan, MD

Matthew J. Ryan, MD, is a Pediatric Gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia.

Areas of Expertise: Airway complications related to GERD, Functional abdominal pain, Primary Sclerosing cholangitis
Locations: Main Campus; Specialty Care & Surgery Center, Voorhees; Specialty Care, Princeton at Plainsboro
Phone: 215-590-3630

Education and Training

Medical School

MD - University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ


Pediatrics - The University of Chicago Children's Hospital, Chicago, IL


Pediatrics - The University of Chicago Children's Hospital, Chicago, IL


Pediatric Gastroenterology (Clinical and Research) - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatric Gastroenterology

Titles and Academic Titles

Attending Physician

Associate Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Research Interests

Pediatric liver disease
Bile duct development
Growth and remodeling
Notch signaling




Ryan M, Underkoffler L, Dutton J, Loomes K: Delayed Biliary Development Leads to Bile Duct Proliferation and Portal Tract Expansion in Mice Heterozygous for Radical Fringe and Jag1 Alleles. Poster Presentation, AASLD annual meeting Boston, MA November 2012.




Ryan JM: Vomiting, Splenomegaly and Asplenia/Hyposplenia. The Five Minute Pediatric Consult, 5th edition. Lippincott Williams and Wilkins, 2008.

Awards and Honors

2016, Fellow's Teaching Award Honor Roll
2015, Fellow's Teaching Award Honor Roll
2006-2008, CDHNF Young Investigator's Development Award
2006, 2nd place Komorov Competition-basic science
2004-2006, NIH Loan Repayment Program

Editorial and Academic Positions

Editorial positions

2011, Journal of Clinical Investigation, Ad hoc reviewer
2010, Human Immunology, Ad hoc reviewer

Academic and institutional committees

2015-present, Chair of the GI ACGME program evaluation committee - PEC
2011-present, Division of GI, Hepatology and Nutrition Second Opinion Committee

Leadership and Memberships

Memberships in professional organization

American Association for the Study of Liver Diseases
American Gastroenterology Association
North American Society of Pediatric Gastroenterology, Hepatology and Nutrition
American Academy of Pediatrics