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Matthew J. Ryan, MD
Matthew J. Ryan, MD

Matthew J. Ryan, MD

Matthew J. Ryan, MD, is a pediatric gastroenterologist at Children's Hospital of Philadelphia with a special interest in liver disease and bile duct development.

Areas of expertise: Airway complications related to GERD, Functional abdominal pain, Primary Sclerosing cholangitis, Transnasal endoscopy

Locations: Specialty Care & Surgery Center, Voorhees, Specialty Care, Atlantic County, Buerger Center for Advanced Pediatric Care

Make an appointment

215-590-3630

About Matthew J. Ryan, MD

Titles

Attending Physician

Associate Professor of Clinical Pediatrics (Gastroenterology, Hepatology and Nutrition), Perelman School of Medicine at the University of Pennsylvania

Certifications

Pediatric Gastroenterology – American Board of Pediatrics

Pediatrics – American Board of Pediatrics

Awards and Honors

2015-2018, Fellow's Teaching Award Honor Roll
2006-2008, CDHNF Young Investigator's Development Award
2006, 2nd place Komorov Competition-basic science
2004-2006, NIH Loan Repayment Program

Leadership and Memberships

Memberships in professional organization

International

2003-present, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition
- 2015-present, Ethics Committee

National

2007-present, American Association for the Study of Liver Diseases
2003-present, The American Gastroenterology Association
2000-present, American Academy of Pediatrics

Editorial and Academic Positions

Editorial positions

2011, Journal of Clinical Investigation, Ad hoc reviewer
2010, Human Immunology, Ad hoc reviewer

Academic and institutional committees

2015-present, Chair of the GI ACGME program evaluation committee - PEC
2011-present, Division of GI, Hepatology and Nutrition Second Opinion Committee

Research Interests

Pediatric liver disease Bile duct development Growth and remodeling Notch signaling

Education & training

Medical Degree

MD - University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ

Internship

Pediatrics - The University of Chicago Children's Hospital, Chicago, IL

Residency

Pediatrics - The University of Chicago Children's Hospital, Chicago, IL

Fellowship

Pediatric Gastroenterology - The Children's Hospital of Philadelphia, Philadelphia, PA
Research Fellow, Pediatric Gastroenterology - The Children's Hospital of Philadelphia, Philadelphia, PA

Team affiliations

 View fewer team affiliations View all team affiliations

Publications

Publications

2021

Aileen Wertz, Matthew Ryan, Ian Jacobs, Joseph Piccione: Impact of Pre-operative Multidisciplinary Evaluation on Laryngotracheal Reconstruction Outcomes. The Laryngoscope 131(7): E2356-E2362, July 2021.

2014

Underkoffler LA, Carr E, Nelson A, Ryan MJ, Schultz R, Loomes KM: Microarray data reveal relationship between Jag1 and Ddr1 in mouse liver. PLoS One 9(1), Jan 2014 Notes: doi: 10.1371/journal.pone.0084383. eCollection

2008

Ryan Matthew J, Bales Christina, Nelson Anthony, Gonzalez Dorian M, Underkoffler Lara, Segalov Michelle, Wilson-Rawls Jeanne, Cole Susan E, Moran Jennifer L, Russo Pierre, Spinner Nancy B, Kusumi Kenro, Loomes Kathleen M: Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype. Hepatology (Baltimore, Md.) 48(6): 1989-97, Dec 2008.

2007

Loomes KM, Russo P, Ryan M, Nelson A, Underkoffler L, Glover C, Hong F, Thomas G, Kaestner K, Oakley R.: Bile Duct Proliferation in Liver Specific Jag Conditional Knockout Mice: Effects of Gene Dosage. Hepatology 45(2): 323-30, January 2007.

Loomes, Kathleen M.  Stevens, Stacey A.  O'Brien, Megan L.  Gonzalez, Dorian M.  Ryan, Matthew J.  Segalov, Michelle.  Dormans, Nicholas J.  Mimoto, Mizuho S.  Gibson, Joshua D.  Sewell, William.  Schaffer, Alyssa A.  Nah, Hyun-Duck.  Rappaport, Eric F.  Pratt, Stephen C.  Dunwoodie, Sally L.  Kusumi, Kenro.: Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects. Developmental Dynamics 236(10): 2943-51, Oct 2007.

Lectures by Invitation
2023

Ryan M. "The ABCs or LFTs" CHOP Nursing lecture, Philadelphia,PA. Oct 2023.

Ryan M. "CHOP Experience with Unsedated Transnasal Endoscopy" EvoEndo Board, Boston. Sept 2023.

Ryan M. "Functional Abdominal Pain" CHOP Harborview Pediatrics. Sept 2023.

Ryan M. "What Goes Down, Sometimes Comes Up", Chester County Hospital. Sept 2023.

2022

Ryan M. GERD in the NICU, Virtu Hospital, Voorhees - Virtual conference. Mar 2022.

2021

Ryan M. To Thicken or Not To Thicken, NASPGHAN Single Topic Symposium, Virtual. Nov 2021.

Editorials, Reviews, Chapters
2008

Ryan JM: Vomiting, Splenomegaly and Asplenia/Hyposplenia. The Five Minute Pediatric Consult, 5th edition. Lippincott Williams and Wilkins, 2008.

Patient experience rating

(based on 82 submissions)
  • Provider listened carefully
    4.9 of 5
  • Trust provider with care
    4.9 of 5
  • Provider gave enough info about child's health
    4.8 of 5
  • Would recommend the provider
    4.7 of 5
Learn about the patient experience rating system

About the Patient Experience Rating System

The patient experience rating is an average of all responses to the care provider-related questions from surveys submitted by patient families and verified by our survey partner National Research Corporation (NRC Health), an independent company that specializes in patient experience. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured using percent positive scoring. Percent positive is the percentage of respondents who answered with the most desirable response. We are committed to transparency and sharing the voices of our patients and families. Comments are reviewed before posting to ensure accuracy, privacy, and relevance. To provide meaningful feedback, comments are displayed on provider profiles once a sufficient number have been received. All feedback is also shared internally to support learning, recognition, and continuous improvement. The comments reflect the experiences and perspectives of the patients and families who submitted them. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.