Education and Training

Medical School

MD - University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ


Pediatrics - The University of Chicago Children's Hospital, Chicago, IL


Pediatrics - The University of Chicago Children's Hospital, Chicago, IL


Pediatric Gastroenterology (Clinical and Research) - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatric Gastroenterology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Attending Physician

Associate Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Research Interests

Pediatric liver disease
Bile duct development
Growth and remodeling
Notch signaling




Danzer E, Hoffman C, D'Agostino J, Ryan M, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Rate and risk factors associated with autism spectrum disorder in congenital diaphragmatic hernia.  Journal of Autism and Developmental Disorders48:2112-2121, 2018. 



Ryan M, Underkoffler L, Dutton J, Loomes K: Delayed Biliary Development Leads to Bile Duct Proliferation and Portal Tract Expansion in Mice Heterozygous for Radical Fringe and Jag1 Alleles. Poster Presentation, AASLD annual meeting Boston, MA November 2012.




Ryan JM: Vomiting, Splenomegaly and Asplenia/Hyposplenia. The Five Minute Pediatric Consult, 5th edition. Lippincott Williams and Wilkins, 2008.

Awards and Honors

2016, Fellow's Teaching Award Honor Roll

2015, Fellow's Teaching Award Honor Roll

2006-2008, CDHNF Young Investigator's Development Award

2006, 2nd place Komorov Competition-basic science

2004-2006, NIH Loan Repayment Program

Editorial and Academic Positions

Editorial positions

2011, Journal of Clinical Investigation, Ad hoc reviewer
2010, Human Immunology, Ad hoc reviewer

Academic and institutional committees

2015-present, Chair of the GI ACGME program evaluation committee - PEC
2011-present, Division of GI, Hepatology and Nutrition Second Opinion Committee

Leadership and Memberships

Memberships in professional organization

American Association for the Study of Liver Diseases

American Gastroenterology Association

North American Society of Pediatric Gastroenterology, Hepatology and Nutrition

American Academy of Pediatrics