Jack Rychik, MD

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Jack Rychik, MD, is Director of the Fetal Heart Program and the Fontan Rehabilitation, Wellness, Activity and Resilience Development (FORWARD) Program at Children’s Hospital of Philadelphia. He holds the Robert and Dolores Harrington Endowed Chair in Pediatric Cardiology.

Areas of Expertise: Echocardiography, Fetal cardiology, Single ventricle physiology
Locations: Main Hospital

Phone: 215-590-4040

Background

As the Director of the Fetal Heart Program and the Fontan Rehabilitation, Wellness, Activity and Resilience Development (FORWARD) Program at Children’s Hospital of Philadelphia (CHOP), Dr. Rychik specializes in the early detection and long-term treatment of complex forms of heart disease and developmental abnormalities. He holds the Robert and Dolores Harrington Endowed Chair in Pediatric Cardiology.

The mission of the Fetal Heart Program is to offer compassionate, state-of-the-art care to the fetus and the family. “I focus on the bookends of care, in addition to the spectrum of what happens in between,” explains Dr. Rychik. “From the earliest point of detection into early adulthood, we are about creating survival and improving the quality of life.”

Early detection affords Dr. Rychik more time for what he views as one of the most important parts of his job — patient and family education. “For me it’s about providing clarity,” he says. “Through direct communication, written materials, diagrams, videos and imaging, we are now able to communicate conditions and care strategies much more effectively.”

Dr. Rychik’s passion for his life’s work is clearly evident. “The exciting thing for me is knowing that there are things I can do, before birth, that can affect what that child and adult is going to eventually be like,” he says. “That’s a profound and wondrous thing.”

As leader of the Single Ventricle Survivorship Clinic, Dr. Rychik is focused on improving therapies. He’s studying the long-term effects of current management strategies for single ventricle conditions. As he explains, “Until recently, children and young adults with these conditions have simply not walked the earth. Treating them is both a challenge and a blessing.”  

Dr. Rychik has also been instrumental in contributing to the field’s knowledge about the cardiac aspects of other congenital conditions. For example, he developed the unique CHOP Scoring System for Twin-Twin Transfusion Syndrome, a potentially fatal condition where twins sharing a placenta experience uneven blood flow. This system allows doctors to better learn the extent of the condition and determine the best approach to treatment.  

He serves on the editorial board of numerous national and international journals, and is a frequent lecturer and presenter at national and international pediatric cardiac conferences on complex cardiovascular disease in both fetal and pediatric patients.

Dr. Rychik has authored more than 250 peer-reviewed research publications, books, reviews, and chapters on fetal and pediatric cardiac disorders and treatment. He is the author of a book entitled Fetal Cardiovascular Imaging: A Disease-Based Approach, which is considered one of the definitive texts on the subject of imaging and management of fetal heart disease.

Dr. Rychik recently established and now leads the CHOP Cardiac Center “FORWARD” Program — a pioneering clinical and investigational effort focused on Fontan Rehabilitation, Wellness and Resilience Development. The endeavor builds upon the Single Ventricle Survivorship Clinic. It aims to bring specialized services to this unique population by offering exercise rehabilitation, mental health and behavioral care, nutrition and dietary needs, and patient-family education to those with a single ventricle and Fontan circulation.

Education and Training

Medical School

MD - State University of New York, Downstate Medical Center, New York, NY

Residency

Pediatrics - Albert Einstein College of Medicine, New York, NY

Fellowship

Pediatric Cardiology - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatric Cardiology
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Associate Chief, Division of Cardiology

Robert S. and Dolores Harrington Endowed Chair in Pediatric Cardiology

Director, Fetal Heart Program

Director, Fontan Rehabilitation, Wellness, Activity and Resilience Development (FORWARD) Program

Acting Director, Non-Invasive Cardiovascular Laboratories

Attending Cardiologist

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2020

Hunt ML, Ittenbach RF, Kaplinski M, Ravishankar C, Rychik J, Steven JM, Fuller SM, Nicolson SC, Spray TL, Gaynor JW, Mascio CE.  : Outcomes for the superior cavopulmonary connection in children with hypoplastic left heart syndrome: a 30-year experience. Eur J Cardiothorac Surg.  Page: doi: 10.1093/ejcts/ezaa117, June 2020 Notes: Epub ahead of print.

Trusty PM, Wei ZA, Rychik J, Graham A, Russo PA, Surrey LF, Goldberg DJ, Yoganathan AP, Fogel MA.   : Cardiac Magnetic Resonance-Derived Metrics Are Predictive of Liver Fibrosis in Fontan Patients. Ann Thorac Surg. 109(6):1904-1911: doi: 10.1016/j.athoracsur, June 2020 Notes: 2019.09.070. Epub 2019 Nov 14.

Ho DY, Josowitz R, Katcoff H, Griffis HM, Tian Z, Gaynor JW, Rychik J.  : Mid-Gestational Fetal Placental Blood Flow is Diminished in the Fetus with Congenital Heart Disease. Prenat Diagn.  Page: doi: 10.1002/pd.5791. July 2020 Notes: Epub ahead of print.

Alsaied T, Allen KY, Anderson JB, Anixt JS, Brown DW, Cetta F, Cordina R, D'udekem Y, Didier M, Ginde S, Di Maria MV, Eversole M, Goldberg D, Goldstein BH, Hoffmann E, Kovacs AH, Lannon C, Lihn S, Lubert AM, Marino BS, Mullen E, Pickles D, Rathod RH, Rychik J, Tweddell JS, Wooton S, Wright G, Younoszai A, Glenn T, Wilmoth A, Schumacher K. : The Fontan outcomes network: first steps towards building a lifespan registry for individuals with Fontan circulation in the United States.     Cardiol Young. 30(8):1070-1075: doi: 10.1017/S1047951120001869. August 2020 Notes: Epub 2020 Jul 8.

Rychik J, Dodds KM, Goldberg D, et al.   : Protein Losing Enteropathy After Fontan Operation: Glimpses of Clarity Through the Lifting Fog. World J Pediatr Congenit Heart Surg. 11(1):92-96: doi:10.1177/2150135119890555, 2020.

2019

Lawrence KM, McGovern PE, Mejaddam A, Rossidis AC, Baumgarten H, Kim A, Grinspan JB, Licht DJ, Didier RA, Vossough A, Radaelli E, Rychik J, Song L, Peranteau WH, Davey MG, Flake AW, Gaynor JW. Chronic intrauterine hypoxia alters neurodevelopment in fetal sheep. J Thorac Cardiovasc Surg. 2019;157(5):1982–1991.

Ozawa K, Davey MG, Tian Z, Hornick MA, Mejaddam AY, McGovern PE, Flake AW, Rychik J. Fetal echocardiographic assessment of the cardiovascular impact of prolonged support in the EXTrauterine Environment for Neonatal Development (EXTEND) system. [Published online ahead of print April 15, 2019] Ultrasound Obstet Gynecol.

Zielonka B, Snarr BS, Liu MY, Zhang X, Mascio CE, Fuller S, Gaynor JW, Spray TL, Rychik J. Resource utilization for prenatally diagnosed single-ventricle cardiac defects: A Philadelphia fetus-to-Fontan cohort study. J Am Heart Assoc. 2019;8(11):e011284.

Russell MW, Moldenhauer JS, Rychik J, Nancy B. Burnham NB, Erin Zullo E, Samuel I Parry S, Simmons RA, Elovitz MA, Nicolson SC, Linn RL, Johnson MP, Yu S, Matthew Sampson M, Hakonarson H, Gaynor JW. Damaging variants in proangiogenic genes impair growth in fetuses with cardiac defects. [Published online ahead of print June 18, 2019] J Pediatr.

2018

Rychik J, Goff D, McKay E, Mott A, Tian Z, Licht DJ, Gaynor JW. Characterization of the placenta in the newborn with congenital heart disease: distinctions based on type of cardiac malformation. Pediatr Cardiol. 2018;39(6):1165–1171.

Lawrence KM, Hennessy-Strahs S, McGovern PE, Mejaddam AY, Rossidis AC, Baumgarten HD, Bansal E, Villeda M, Han J, Gou Z, Zhao S, Rychik J, Peranteau WH, Davey MG, Flake AW, Gaynor JW, Bartoli CR. Fetal hypoxemia causes abnormal myocardial development in a preterm ex utero fetal ovine model. JCI Insight. 2018;3(24).

Liu MY, Zielonka B, Snarr BS, Zhang X, Gaynor JW, Rychik J. Longitudinal Assessment of Outcome From Prenatal Diagnosis Through Fontan Operation for Over 500 Fetuses With Single Ventricle‐Type Congenital Heart Disease: The Philadelphia Fetus‐to‐Fontan Cohort Study. J Am Heart Assoc. 2018 Sept. 29;7(19):e009145.

Gaynor JW, Parry S, Moldenhauer JS, Simmons RA, Rychik J, Ittenbach RF, Russell WW, Zullo E, Ward JL, Nicolson SC, Spray TL, Johnson MP. The impact of the maternal-fetal environment on outcomes of surgery for congenital heart disease in neonates. Eur J Cardiothorac Surg. 2018 Feb 13. doi: 10.1093/ejcts/ezy015. [Epub ahead of print] PMID: 29447332 [PubMed - as supplied by publisher]

2017

Partridge EA, Davey MG, Hornick MA, McGovern PE,  Mejaddam AY, Vrecenak JD, Mesas-Burgos C, Olive A, Caskey RC, Weiland TR, Han J, Schupper AJ, Connelly JT, Dysart KC, Rychik J, Hedrick HL, Peranteau WH, Flake AW. Corrigendum: An extra-uterine system to physiologically support the extreme premature lamb. Nat Commun. 2017 May 23;8:15794. Doi: 10.1038/ncomms15794.

Emily A. Partridge, Marcus G. Davey, Matthew A. Hornick, Patrick E. McGovern, Ali Y. Mejaddam, Jesse D. Vrecenak, Carmen Mesas-Burgos, Aliza Olive, Robert C. Caskey, Theodore R. Weiland III, Jiancheng Han, James T. Connelly, Kevin C. Dysart, Alexander J. Schupper, Jack Rychik, Holly L. Hedrick, William H. Peranteau, and Alan W. Flake. “An extra-uterine physiologic support system for the extreme premature lamb.” Nature Communications. Published online April 25, 2017.

2016

Rychik J, Khalek N, Gaynor JW, Johnson MP, Adzick NS, Flake AM, Hedrick HL. Fetal intrapericardial teratoma: natural history and management including successful in utero surgery. Am J Obstet Gynecol. 2016 Dec;215(6):780.e1-780.e7.

Saul D, Degenhardt K, Iyoob SD, Surrey LF, Johnson AM, Johnson MP, Rychik J, Victoria T. Hypoplastic left heart syndrome and the nutmeg lung pattern in utero: a cause and effect relationship or prognostic indicator? Pediatr Radiol. 2016 Apr;46(4):483-9. doi: 10.1007/s00247-015-3514-6. Epub 2015 Dec 21.

Saul D, Degenhardt K, Iyoob SD, Surrey LF, Johnson AM, Johnson MP, Rychik J, Victoria T. Hypoplastic left heart syndrome and the nutmeg lung pattern in utero: a cause and effect relationship or prognostic indicator? Pediatr Radiol. 2016 Apr;46(4):483-9.

2015

Saul D, Degenhardt K, Iyoob SD, Surrey LF, Johnson AM, Johnson MP, Rychik J, Victoria T. Hypoplastic left heart syndrome and the nutmeg lung pattern in utero: a cause and effect relationship pr prognostic indicator? Pediatr Radiol 2015 [Epub ahead of print]. 

Patel K, Loomes KM, Goldberg DJ, Mercer-Rosa L, Dodds K, Rychik J. Early impact of Fontan operation on enteric protein loss. Ann Thorac Surg 2015 Nov 30 [Epub ahead of print].

Davey BT, Rychik J. The Natural History of Atrioventricular Valve Regurgitation Throughout Fetal Life in Patients with Atrioventricular Canal Defects. Pediatr Cardiol. 2015 Aug 4. [Epub ahead of print].

Avitabile CM, Goldberg DJ, Zemel BS, Brodsky JL, Dodds K, Hayden-Rush C, Whitehead KK, Goldmuntz E, Rychik J, Leonard MB. Deficits in bone density and structure in children and young adults following Fontan palliation. Bone 2015 Aug;77:12-6. doi: 10.1016/j.bone.2015.04.012. Epub 2015 Apr 14.

Brandt JS, Wang E, Rychik J, Soffer D, McCann ML, Schwartz N. Utility of a Single 3-Vessel View in the Evaluation of the Ventricular Outflow Tracts. J Ultrasound Med. 2015 Aug;34(8):1415-21. doi: 10.7863/ultra.34.8.1415.

Avitabile CM, Leonard MB, Brodsky JL, Whitehead KK, Ravishankar C, Cohen MS, Gaynor JW, Rychik J, Goldberg DJ. Usefulness of insulin like growth factor 1 as a marker of heart failure in children and young adults after the Fontan palliation procedure. Am J Cardiol. 2015 Mar 15;115(6):816-20. doi: 10.1016/j.amjcard.2014.12.041. Epub 2015 Jan 6.

Mercer-Rosa L, Paridon SM, Fogel MA, Rychik J, Tanel RE, Zhao H, Zhang X, Yang W, Shults J, Goldmuntz E. 22q11.2 deletion status and disease burden in children and adolescents with tetralogy of Fallot. Circ Cardiovasc Genet. 2015 Feb;8(1):74-81. doi: 10.1161/CIRCGENETICS.114.000819. Epub 2015 Jan 5.

Juaneda I, Rychik J, Fuller S, Weinberg PM, Rome JJ, Mahle WT, Gaynor JW. Absent pulmonary valve, tricuspid atresia, and congenital heart block. World J Pediatr Congenit Heart Surg. 2015 Jan;6(1):98-100. doi: 10.1177/2150135114544752.

2014

Channing A, Szwast A, Natarajan S, Degenhardt K, Tian Z, Rychik J. Maternal Hyperoxygenation Improves Left Heart Filling In The Fetus With Atrial Septal Aneurysm Causing Impediment To Left Ventricular Inflow. Ultrasound Obstet Gynecol. 2014 Oct 9. doi: 10.1002/uog.14688. [Epub ahead of print]. 

Peyvandi S, Rychik J, Zhang X, Shea JA, Goldmuntz E. Preconceptual Folic Acid Use and Recurrence Risk Counseling for Congenital Heart Disease. Congenit Heart Dis. 2014 Jul 24. doi: 10.1111/chd.12206. [Epub ahead of print].

Rychik J, Cohen D, Tran KM, Szwast A, Natarajan SS, Johnson MP, Moldenhauer JS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Adzick NS. The Role of Echocardiography in the Intraoperative Management of the Fetus Undergoing Myelomeningocele Repair. Fetal Diagn Ther. 2014 Jul 18. [Epub ahead of print].

Dori Y, Keller MS, Rychik J, Itkin M. Successful Treatment of Plastic Bronchitis by Selective Lymphatic Embolization in a Fontan Patient. Pediatrics 2014 Jul 7. pii: peds.2013-3723. [Epub ahead of print].

Avitabile CM, Leonard MB, Zemel BS, Brodsky JL, Lee D, Dodds K, Hayden-Rush C, Whitehead KK, Goldmuntz E, Paridon SM, Rychik J, Goldberg DJ. Lean mass deficits, vitamin D status and exercise capacity in children and young adults after Fontan palliation. Heart 2014 Jun 27. pii: heartjnl-2014-305723. doi: 10.1136/heartjnl-2014-305723. [Epub ahead of print]. 

Avitabile CM, Goldberg DJ, Dodds K, Dori Y, Ravishankar C, Rychik J. A Multifaceted Approach to the Management of Plastic Bronchitis After Cavopulmonary Palliation. Ann Thorac Surg 2014 Aug;98(2):634-40. doi: 10.1016/j.athoracsur.2014.04.015. Epub 2014 May 17.

Davey BT, Donofrio MT, Moon-Grady AJ, Fifer CG, Cuneo BF, Falkensammer CB, Szwast AL, Rychik J. Development and Validation of a Fetal Cardiovascular Disease Severity Scale. Pediatr Cardiol Oct;35(7):1174-80. doi: 10.1007/s00246-014-0911-9. Epub 2014 May 7.

Donofrio MT, Moon-Grady AJ, Hornberger LK, Copel J, Sklansky M, Abuhamad A, Cuneo B, Huhta JC, Jonas RA, Krishnan A, Lacey S, Lee W, Michelfelder E, Rempel G, Silverman NH, Spray TL, Strasburger J, Twortetzky W, and Rychik J. Diagnosis and Treatment of Fetal Cardiac Disease: A Scientific Statement from the American Heart Association. Circulation 2014 May 27;129(21):2183-242. doi: 10.1161/01.cir.0000437597.44550.5d. Epub 2014 Apr 24.

O’Byrne ML, Mercer-Rosa L, Zhao H, Zhang X, Yang W, Tanel RE, Marino BS, Cassedy A, Fogel MA, Rychik J, Paridon S, Goldmuntz E. Morbidity in Children and Adolescents After Surgical Correction of Interrupted Aortic Arch. Pediatr Cardiol. 2014;35:386-92.

Szwast A, Tian Z, McCann M, Soffer D, Combs J, Donaghue D, Rychik J. Anatomical variability and outcome in prenatally diagnosed absent pulmonary valve syndrome. Ann Thorac Surg 2014 Jul;98(1):152-8. doi: 10.1016/j.athoracsur.2014.03.002. Epub 2014 May 1.

2013

Natarajan S, Szwast A, Tian Z, McCann M, Soffer D, Rychik J:  Right Ventricular Mechanics in the Fetus with Hypoplastic Left Heart Syndrome. J Am Soc Echocardiogr Mar 5 2013 Notes: doi:pii: S0894-7317(13)00092-8. 10.1016/j.echo.2013.02.001[Epub ahead of print]

Rossano JW, Woods RK, Berger S, Gaynor JW, Ghanayem N, Morales DL, Ravishankar C, Mitchell ME, Shah TK, Mahr C, Tweddell JS, Adachi I, Zangwill S, Wearden PD, Icenogle TB, Jaquiss RD, Rychik J: Mechanical Support as Failure Intervention in Patients with Cavopulmonary Shunts (MFICS): Rationale and Aims of a New Registry of Mechanical Circulatory Support in Single Ventricle Patients. Congenit Heart Dis   Page: doi: 10.1111/chd.12053.  Mar 20 2013 Notes: [Epub ahead of print]

John AS, Rychik J, Khan M, Yang W, Goldmuntz E   : 22q11.2 deletion syndrome as a risk factor for aortic root dilation in tetralogy of Fallot. Cardiol Young Page: 1-8, Apr 10 2013 Notes: [Epub ahead of print] PMID: 23570688.

Peyvandi S, Rychik J, McCann M, Soffer D, Tian Z, Szwast A : Pulmonary blood flow patterns in fetuses with pulmonary outflow tract obstruction. Ultrasound Obstet Gynecol Page:  doi: 10.1002/uog.12472.  Apr 1 2013 Notes:  [Epub ahead of print]

Davey B, Thacker D, Rychik J    : Atrioventricular Valve Regurgitation in the Fetus With Atrioventricular Canal Defect: Transition From Prenatal to Postnatal Life. Pediatr Cardiol May 12 2013 Notes: [Epub ahead of print] PMID: 23666083.

O'Byrne Michael L, Mercer-Rosa Laura, Zhao Huaqing, Zhang Xuemei, Yang Wei, Cassedy Amy, Fogel Mark A, Rychik Jack, Tanel Ronn E, Marino Bradley S, Paridon Stephen, Goldmuntz Elizabeth: Morbidity in children and adolescents after surgical correction of truncus arteriosus communis. American heart journal 166(3): 512-8, Sep 2013.

O'Byrne ML, Mercer-Rosa L, Zhao H, Zhang X, Yang W, Tanel RE, Marino BS, Cassedy A, Fogel MA, Rychik J, Paridon S, Goldmuntz E   : Morbidity in Children and Adolescents After Surgical Correction of Interrupted Aortic Arch. Pediatr Cardiol  Sep 15 2013 Notes: [Epub ahead of print]

Molina KM, Shrader P, Colan SD, Mital S, Margossian R, Sleeper LA, Shirali G, Barker P, Canter CE, Altmann K, Radojewski E, Tierney ES, Rychik J, Tani LY  : Pediatric Heart Network Investigators. Predictors of disease progression in pediatric dilated cardiomyopathy. Circ Heart Fail 1;6(6): 1214-22,  Nov 2013 Notes: doi: 10.1161/CIRCHEARTFAILURE.113.000125. Epub 2013 Oct 16.

Oliver ER, Coleman BG, Goff DA, Horii SC, Howell LJ, Rychik J, Bebbington MW, Johnson MP    : Twin reversed arterial perfusion sequence: a new method of parabiotic twin mass estimation correlated with pump twin compromise. J Ultrasound Med 32(12): 2115-23, Dec 2013 Notes:  doi: 10.7863/ultra.32.12.2115.

O'Byrne ML, Mercer-Rosa L, Zhao H, Zhang X, Yang W, Fogel MA, Rychik J, Tanel R, Marino B, Paridon S, Goldmuntz E : Morbidity in children and adolescents following surgical correction of truncus arteriosus communis. Am Heart J 166: 512-518, 2013.

2012

Goldberg DJ, Dodds K, Avitabile CM, Glatz AC, Brodsky JL, Semeao E, Rand E, Mancilla EE, Rychik J    : Children with protein losing enteropathy after Fontan operation are at risk for abnormal bone mineral density. Pediatr Cardiol Mar 21 2012 Notes: [Epub ahead of print]

Quartermain MD, Glatz AC, Goldberg DJ, Cohen MS, Elias MD, Tian Z, Rychik J      : Pulmonary Outflow Obstruction in the Fetus with Complex Congenital Heart Disease: predicting the need for neonatal intervention. Ultrasound Obstet Gynecol Page: doi: 10.1002/uog.11196, May 17 2012 Notes: [Epub ahead of print]

Rychik J, Zeng Shi, Bebbington M, Szwast A, Quartermain M, Natarajan S, Johnson M, Tian ZY   : Speckle-tracking derived myocardial tissue deformation imaging in twin-twin transfusion syndrome: differences in strain and strain rate between donor and recipient twins. Fetal Diagn Ther May 16 2012 Notes: [Epub ahead of print]

Colan SD, Shirali G, Margossian R, Gallagher D, Altmann K, Canter C, Chen S, Golding F, Radojewski E, Camitta M, Carboni M, Rychik J, Stylianou M, Tani LY, Selamet Tierney ES, Wang Y, Sleeper LA : Pediatric Heart Network Investigators. The Ventricular Volume Variability Study of the Pediatric Heart Network: Study Design and Impact of Beat Averaging and Variable Type on the Reproducibility of Echocardiographic Measurements in Children with Chronic Dilated Cardiomyopathy. J Am Soc Echocardiogr  Jun 5 2012 Notes: [Epub ahead of print]

Szwast A, Tian Z, McCann M, Soffer D, Rychik J  : Comparative analysis of cerebrovascular resistance in fetuses with single-ventricle congenital heart disease. Ultrasound Obstet Gynecol 40(1):62-7: doi: 10.1002/uog.11147, Jul 2012 Notes: Epub 2012 Jun 8.

Mercer-Rosa L, Yang W, Kutty S, Rychik J, Fogel M, Goldmuntz E    : Quantifying pulmonary regurgitation and right ventricular function in surgically repaired tetralogy of Fallot: a comparative analysis of echocardiography and magnetic resonance imaging. Circ Cardiovasc Imaging 1;5(5): 637-43, Sep 2012 Notes: Epub 2012 Aug 6.

Rogers LS, Glatz AC, Ravishankar C, Spray TL, Nicolson SC, Rychik J, Rush CH, Gaynor JW, Goldberg DJ  : 18 years of the Fontan operation at a single institution: results from 771 consecutive patients. J Am Coll Cardiol 60(11): 1018-25, Sep 11 2012 Notes: doi: 10.1016/j.jacc.2012.05.010. Epub 2012 Jul 18.

Rychik J, Donaghue DD, Levy S, Fajardo C, Combs J, Zhang X, Szwast A, Diamond GS   : Maternal psychological stress after prenatal diagnosis of congenital heart disease. J Pediatr Sep 10  2012 Notes: doi:pii: S0022-3476(12)00801-3. 10.1016/j.jpeds.2012.07.023. [Epub ahead of print]

Goff DA, Luan X, Gerdes M, Bernbaum J, D'Agostino JA, Rychik J, Wernovsky G, Licht DJ, Nicolson SC, Clancy RR, Spray TL, Gaynor JW : Younger gestational age is associated with worse neurodevelopmental outcomes after cardiac surgery in infancy. J Thorac Cardiovasc Surg  143: 535-42, 2012.

Goldberg DJ, French B, Szwast AL, McBride MG, Marino BS, Mirarchi N, Hanna BD, Wernovsky G, Paridon SM, Rychik J   : Impact of sildenafil on echocardiographic indices of myocardial performance after Fontan operation. Pediatr Cardiol  DOI 10.1007/s002: 46-012-0196-9, 2012.

Lasa JJ, Tian ZY, Guo R, Rychik J  : Perinatal course of Ebstein's anomaly and tricuspid valve dysplasia in the fetus. Prenat Diagn 32: 245-51, 2012.

2011

Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, D'Alton ME, Farmer DL : MOMS Investigators. A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med  364(11): 993-1004,  2011.

Goldberg DJ, French B, McBride MG, Marino BS, Mirarchi N, Hanna BD, Wernovsky G, Paridon SM, Rychik J   : Impact of oral sildenafil on exercise performance in children and young adults after the Fontan operation: a randomized, double-blind, placebo-controlled, crossover trial. Circulation 123(11): 1185-93, 2011.

Peterson AL, Quartermain MD, Ades A, Khalek N, Johnson MP, Rychik J  : Impact of mode of delivery on markers of perinatal hemodynamics in infants with hypoplastic left heart syndrome. J Pediatr  159(1): 64-9, 2011.

Rogers LS, Peterson AL, Gaynor JW, Rome JJ, Weinberg PM, Rychik J   : Mitral valve dysplasia syndrome: a unique form of left-sided heart disease. J Thorac Cardiovasc Surg 142: 1381-7, 2011.

Sleeper LA, Minich LL, McCrindle BM, Li JS, Mason W, Colan SD, Atz AM, Printz BF, Baker A, Vetter VL, Newburger JW  : Pediatric Heart Network Investigators. Evaluation of Kawasaki disease risk-scoring systems for intravenous immunoglobulin resistance. J Pediatr 158: 831-835e, 2011.

Szwast AL, Marino BS, Rychik J, Gaynor JW, Spray TL, Cohen, MS  : Usefulness of left ventricular inflow index to predict successful biventricular repair in right-dominant unbalanced atrioventricular canal. Am J Cardiol 107: 103-9, 2011.

2010

Atz AM, Travison TG, Williams IA, Pearson GD, Laussen PC, Mahle WT, Cook AL, Kirsh JA, Sklansky M, Khaikin S, Goldberg C, Frommelt M, Krawczeski C, Puchalski MD, Jacobs JP, Baffa JM, Rychik J, Ohye RG  : Pediatric Heart Network Investigators. Prenatal diagnosis and risk factors for preoperative death in neonates with single right ventricle and systemic outflow obstruction: Screening data from the Pediatric Heart Network Single Ventricle Reconstruction Trial. J Thorac Cardiovasc Surg 140: 1245-50, 2010.

Nathan AT, Marino BS, Dominguez T, Tabbutt S, Nicolson S, Donaghue DD, Spray TL, Rychik J  : Tricuspid valve dysplasia with severe tricuspid regurgitation: fetal pulmonary artery size predicts lung viability in the presence of small lung volumes. Fetal Diagn Ther 27: 101-105, 2010.

Rychik J, McCann M, Tian Z, Bebbington M, Johnson M : Fetal cardiovascular effects of lower urinary tract obstruction with giant bladder. Ultrasound Obstet Gynecol  36: 682-6, 2010.

Rychik J, Szwast A, Natarajan S, Quartermain M, Donaghue DD, Combs J, Gaynor JW, Gruber PJ, Spray TL, Bebbington M, Johnson MP : Perinatal and early surgical outcome for the fetus with hypoplastic left heart syndrome: A five-year single institutional experience. Ultrasound Obstet Gynecol  36: 465-70  2010.

Thacker D, Patel A, Dodds K, Goldberg DJ, Semeao E, Rychik J   : Use of Oral Budesonide in the Management of Protein Losing Enteropathy after the Fontan Operation. Ann Thorac Surg 89: 837-842, 2010.

2009

Margossian R, Schwartz ML, Prakash A, Wruck L, Colan SD, Atz AM, Bradley TJ, Fogel MA, Hurwitz LM, Marcus E, Powell AJ, Printz BF, Puchalski MD, Rychik J, Shirali G, Williams R, Yoo SJ, Geva T  : Pediatric Heart Network Investigators. Comparison of echocardiographic and cardiac magnetic resonance imaging measurements of functional single ventricular volumes, mass, and ejection fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study). Am J Cardiol 104: 419-28, 2009.

Marino BS, Kruge LE, Cho CJ, Tomlinson RS, Shera D, Weinberg PM, Gaynor JW, Rychik J  2009;137:385-393: Parachute mitral valve: morphologic descriptors, associated lesions, and outcomes after biventricular repair. J Thorac Cardiovasc Surg 137: 385-393, 2009.

Quartermain MD, Cohen MS, Dominguez T, Tian Z, Donaghue DD, Rychik J : Left ventricle to right ventricle size discrepancy in the fetus: the presence of critical congenital heart disease can be reliably predicted. J Am Soc Echocardiogr  22: 1296-1301, 2009.

Slodki M, Rychik J, Moszura T, Janiak K, Respondek-Liberska M : Measurement of the great vessels in the mediastinum could help distinguish true from false-positive coarctation of the aorta in the third trimester. J Ultrasound Med  28: 1313-1317, 2009.

Szwast A, Tian Z, Donaghue D, Rychik J 2009;87:1214-1219: Right Ventricular Performance in the Fetus with Hypoplastic Left Heart Syndrome. Ann Thorac Surg  87: 1214-1219, 2009.

Szwast A, Tian Z, McCann M, Donaghue D, Rychik J  : Vasoreactive response to maternal hyperoxygenation in the fetus with hypoplastic left heart syndrome  Circ Cardiovasc Imaging December 2009 Notes: [Epub ahead of print]

2008

Blaufox AD, Sleeper LA, Bradley DJ, Breitbart RE, Hordof A, Kanter RJ, Stephenson EA, Stylianou M, Vetter VL, Saul JP   : Pediatric Heart Network Investigators. Functional status, heart rate, and rhythm abnormalities in 521 Fontan patients 6 to 18 years of age. J Thorac Cardiovasc Surg 136: 100-7, 2008.

Chintala K, Tian, Z, Du  W, Donaghue D, Rychik J   : Fetal pulmonary venous Doppler patterns in hypoplastic left heart syndrome: relationship to atrial restriction. Heart 94: 1446-9, 2008.

Dorfman AT, Marino BS, Wernovsky G, Tabbutt S, Ravishankar C, Godinez RI, Priestley M, Dodds KM, Rychik, J, Gruber PJ, Gaynor JW, Levy RJ, Nicoslon SC, Montenegro LM, Spray TL, Dominguez TE: Critical heart disease in the neonate: presentation and outcome at a tertiary care center. Pediatr Crit Care Med  9: 193-202, 2008.

Glatz AC, Gaynor JW, Rhodes LA, Rychik J, Tanel RE, Vetter VL, Kaltman JR, Nicolson SC, Montenegro L, Shah MJ  : Outcome of high risk neonates with congenital complete heart block paced in the first 24 hours of life. J Thorac Cardiovasc Surg 136: 767-773, 2008.

Marino BS, Pasquali SK, Wernovsky G, Pudusseri A, Rychik J, Montenegro LM, Shera D, Spray TL, Cohen MS    : Accuracy of intraoperative transesophageal echocardiography in the prediction of future neo-aortic valve function after the Ross procedure in children and young adults. Congenit Heart Dis 3: 39-46, 2008.

Merriman J, Gonzalez J, Rychik J, Parre E    : Can digoxin and sotalol therapy for fetal supraventricular tachycardia and hydrops be successful? J Reproductive Med 53: 357-359, 2008.

Wilson RD, Hedrick H, Flake AW, Johnson MP, Bebbington MW, Mann S, Rychik J, Liechty K, Adzick NS  2008;25:15-20 : Sacrococcygeal teratoma: prenatal surveillance, growth and pregnancy outcome. Fetal Diagnosis and Therapy 25: 15-20, 2008.

2007

Crombleholme TM, Shera D, Lee H, Johnson M, D'Alton M, Porter F, Chyu J, Silver R, Abuhamad A, Saade G, Shields L, Kauffman D, Stone J, Albanese CT, Bahado-Singh R, Ball RH, Bilaniuk L, Coleman B, Farmer D, Feldstein V, Harrison MR, Hedrick H, Livingston J, Lorenz RP, Miller DA, Norton ME, Polzin WJ, Robinson JN, Rychik J, Sandberg PL, Seri I, Simon E, Simpson LL, Yedigarova L, Wilson RD, Young B  : A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome. Am J Obstet Gynecol 197: 396.e1-9, 2007.

Ferdman BR, States L, Gaynor JW, Hedrick H, Rychik J  : Abnormalities of intestinal rotation in patients with heterotaxy syndrome and congenital heart disease. Congenit Heart Dis  2: 12-18, 2007.

Glatz JA, Tabbutt S, Gaynor JW, Rome JJ, Spray TL, Rychik J  : Hypoplastic left heart syndrome and intact or highly restrictive atrial septum: outcome in the current era of prenatal diagnosis. Ann Thorac Surg 84: 1633-8,  2007.

Hüsler MR, Wilson RD, Rychik J, Bebbington MW, Johnson MP, Mann SE, Hedrick HL, Adzick NS 2007; 27:1123-8: Prenatally diagnosed fetal lung lesions with associated conotruncal heart defects: Is there a genetic association?  Prenatal Diag 27: 1123-8, 2007.

Rychik J, Tian Z, Bebbington M, Feng X, McCann M, Mann S, Wilson RD, Johnson MP : The twin-twin transfusion syndrome: spectrum of cardiovascular abnormality and development of a cardiovascular score to assess severity of disease.  Am J Obstet Gynecol 197: 392.e1-8, 2007.

Shillingford AJ, Ittenbach RF, Marino BS, Rychik J, Clancy RR, Spray TL, Gaynor JW, Wernovsky G  : Aortic morphometry and microcephaly in hypoplastic left heart syndrome. Cardiol Young 17: 189-95, 2007.

Szwast AL, Tian Z, McCann M, Donaghue D, Rychik J  : Flow derived measures of ventricular performance in the fetus.  Ultrasound Obstet Gynecol 30: 40-46, 2007.

2006

Cohen MS, Schultz AH, Tian ZY, Donaghue DD, Weinberg PM, Gaynor JW, Rychik J   : Heterotaxy syndrome with functional single ventricle: Does prenatal diagnosis improve survival? Ann Thorac Surg 82: 1629-36, 2006.

Ismat FA, Weinberg PM, Rychik J, Karl TR, Fogel MA   : Right aortic arch and coarctation: a rare association. Congenit Heart Dis 1: 217-223, 2006.

Lai W, Geva T, Shirali G, Frommelt PC, Humes RA, Brook MM, Pignatelli RH, Rychik J   : Guidelines and standards for performance of a pediatric echocardiogram. J Am Soc Echocardiogr 19: 1413-30, 2006.

Mercer-Rosa L, Seliem MA, Fedec A, Rome J, Rychik J, Gaynor JW  : Illustration of the additional value of real-time 3-dimensional echocardiography to conventional transthoracic and transesophageal 2-dimensional echocardiography in imaging muscular ventricular septal defects: Does this have any impact on individual patient treatment? J Am Soc Echocardiogr  19: 1511-1519, 2006.

Ostrow AM, Freeze H, Rychik J   : Protein-losing enteropathy after Fontan operation: Investigations into possible pathophysiological mechanisms. Ann Thorac Surg 82: 695-700, 2006.

Seliem MA, Fedec A, Cohen MS, Ewing S, Farrell PE, Rychik J, Schultz AH, Gaynor JW, Spray TL : Real-time 3-dimensional echocardiographic imaging of congenital heart disease using matrix-array technology: freehand real-time scanning adds instant morphologic details not well delineated by conventional 2-dimensional imaging. J Am Soc Echocardiogr  19: 121-129, 2006.

Wernovsky G, Rome JJ, Tabbutt S, Rychik J, Cohen MS, Paridon SM, Webb G, Dodds KM, Gallagher MA, Fleck DA, Spray TL, Vetter VL, Gleason MM: Guidelines for the outpatient management of complex congenital heart disease. Congenital Heart Dis  1: 10-26, 2006.

2005

Ayres N, Miller-Hance W, Fyfe DA, Stevenson JG, Sahn DJ, Pagatto-Young L, Minich L, Kimball TR, Geva T, Smith F, Rychik J   : American Society of Echocardiography indications and guidelines for performance of transesophageal echocardiography in the patient with pediatric acquired or congenital heart disease. J Am Soc Echocardiogr 18: 91-8, 2005.

Fogel M, Wilson RD, Flake A, Johnson M, Cohen D, McNeal G, Tian ZY, Rychik J    : Preliminary investigations into a new method of functional assessment of the fetal heart using a novel application of "real time" cardiac magnetic resonance imaging. Fetal Diagnosis and Therapy 20: 475-480, 2005.

Hoehn SK, Wernovsky G, Rychik J, Gaynor JW, Spray TL, Feudtner C: What factors are important to parents making decisions about neonatal research?  Arch Dis Child Fetal Neonatal Ed 90: F267-F269, 2005.

Kaltman JR, Di H, Tian Z, Rychik J  : Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus. Ultrasound Obstet Gynecol 25: 32-6, 2005.

Keswani SG, Crombleholme TM, Rychik J, Tian Z, MacKenzie TC, Johnson MP, Wilson RD, Flake AW, Hedrick HL, Howell LJ, Adzick NS  : Impact of Continuous Intraoperative Monitoring on Outcomes in Open Fetal Surgery. Fetal Diagnosis and Therapy  20: 316-320, 2005.

2004

Ginsberg JP, Cnaan A, Zhao Huaquing, Clark BJ, Paridon SM, Chin AJ, Rychik J, Hogarty AN, Barber G, Rutkowski M, Kimball TR, DeLaat C, Steinherz LJ, Silber JH   : Using health related quality of life measures to predict cardiac function in survivors exposed to anthracyclines. J Clin Oncol 22: 3149-3155, 2004.

Hoehn S, Wernovsky G, Rychik J, Tian ZY, Donaghue DD, Alderfer J, Gaynor JW, Kazak AE, Spray TL, Nelson RM : Assessment of parental stress and decision making in congenital heart disease: prenatal versus postnatal diagnosis. Cardiol Young 14: 309-14,  2004.

Lodge AJ, Rychik J, Nicolson SC, Ittenbach RF, Spray TL, Gaynor JW   : Improving outcomes in functional single ventricle and total anomalous pulmonary venous connection. Ann Thorac Surg 78: 1688-1695, 2004.

Ro PS, Rychik J, Cohen MS, Mahle WT, Rome J  : Diagnostic assessment before Fontan operation in patients with bi-directional cavopulmonary anastomosis: are non-invasive methods sufficient? J Am Coll Cardiol 44: 184-187, 2004.

Ro, PS, Rychik, J, Cohen, MS, Mahle, WT, Rome, J: Diagnostic Assessment Before Fontan Operation in Patients with Bi-Directional cavopulmonary Anastomosis: are Non -Invasive Methods Sufficient? J Am Coll Cardiol  2004 Notes: In Press.

Rychik J, Ayres N, Cuneo B, Gotteiner N, Hornberger L, Spevak PJ, Van Der Veld M  : American Society of Echocardiography guidelines and standards for performance of the fetal echocardiogram. J Am Soc Echocardiogr 17: 803-10, 2004.

Rychik J, Tian T, Cohen MS, Ewing SG, Cohen D, Howell LJ, Wilson DR, Johnson MP, Hedrick HL, Flake AW, Crombleholme TM, Adzick NS  : Acute cardiovascular effects of fetal surgery in the human. Circulation 110: 1549-1556, 2004.

Sillber JH, Cnaan A, Clark BJ, Paridon SM, Chin AJ, Rychik J, Hogarty AN, Cohen MI, Barber G, Rutkowski M, Kimball TR, DeLaat C, Steinherz LJ, Zhao H : Enalapril to prevent cardiac function decline in long-term survivors of pediatric cancer exposed to anthracyclines. J Clin Oncol  22: 820-828, 2004.

2003

Rychik J, Yang SG  : Relation of mesenteric vascular resistance after Fontan operation and protein-losing enteropathy.  Am J Cardiol 90: 672-674, 2002.

Petko M, Myung RJ, Cohen MI, Wernovsky G, Rychik J, Nicolson SC, Gaynor JW, Spray TL  : Surgical reinterventions following the Fontan procedure. Eur J Cardiothorac Surg  24: 255-259, 2003.

Quinones MA, Douglas PS, Foster E, Gorcsan J, Lewis JF, Pearlman AS, Rychik J, Salcedo EE, Seward J, Stevenson JG, Thys DM, Weitz HH, Zoghbi WA  : Competence statement in echocardiography: a report of the ACC/AHA/ACP-ASIM task force on clinical competence. J Am Coll Cardiol 41: 687-708, 2003.

2002

Bergqvist AGC, Chee CM, Lutchka L, Rychik J, Stallings VA : Selenium deficiency associated with cardiomyopathy: a complication of the ketogenic diet.  Epilepsia  2002.

Cohen MS, Rychik J, Bush DM, Tian ZY, Howell LJ, Adzick NS, Flake AW, Johnson MP, Spray TL, Crombleholme TM : Influence of congenital heart disease on survival in children with congenital diaphragmatic hernia.  J Pediatr 141: 25-30, 2002.

2001

Cohen M, Rhodes LA, Wernovsky G, Gaynor JW, Spray TL, Rychik J: Atrial pacing: an alternative treatment for protein-losing enteropathy after Fontan operation. J Thorac Cardiovasc Surg  121: 582-583, 2001.

Cohen MS, Coon P, Weinberg PM, Gaynor JW, Karl TR, Spray TL, Rychik J  : Deviation of atrial septum primum in association with normal left atrioventricular valve size. J Am Soc Echocardiogr  14: 732-737, 2001.

Coon PD, Gaynor JW, Spray TL, Rychik J  : Thrombus formation after Fontan operation. Ann Thorac Surg 71: 1990-1994, 2001.

Fogel MA, Rychik J, Chin AJ, Hubbard A, Weinberg PM   : Evaluation and follow-up of patients with left ventricular apical to aortic conduits with 2D and 3D magnetic resonance imaging and Doppler echocardiography: a new look at an old operation. Am Heart J 141: 630-636, 2001.

Gaynor JW, O'Brien JE, Rychik J, Sanchez GR, DeCampli WM, Spray TL : Outcome following tricuspid valve detachment for ventricular septal defect closure. Eur J Cardiothorac Surg  19: 279-282, 2001.

Mahle W, Coon PD, Wernovsky G, Rychik  2001;11:399-406: Quantitative echocardiographic assessment of the performance of the functionally single right ventricle after the Fontan operation. J Cardiology in the Young 11: 399-406, 2001.

Mahle WT, Cohen MS, Spray TL, Rychik J : Atrioventricular valve regurgitation in patients with single ventricle: impact of the bidirectional cavopulmonary anastomosis. Ann Thorac Surg 72: 831-835,  2001.

Mahle WT, Rychik J, Gaynor JW, Spray TL, Rome JJ : Restrictive inter-atrial communication following reconstructive surgery for hypoplastic left heart syndrome    Am J Cardiol  88: 1454-1457, 2001.

McElhinney DB, Yang SG, Hogarty AN, Rychik J, Gleason MM, Zachary CH, Rome JJ, Karl TR, DeCampli WM, Spray TL, Gaynor JW  : Recurrent arch obstruction after repair of isolated coarctation of the aorta in neonates and young infants: Is low weight a risk factor? J Thorac Cardiovasc Surg 128: 883-890,  2001.

Silber JH, Cnaan A, Clark BJ, Paridon SM, Chin AJ, Rychik J, Hogarty AN, Cohen MI, Barber G, Rutkowsky MM, Kimball TR, DeLaat C, Steinherz LJ, Zhao H, Tartaglione MR  : Design and baseline characteristics for the ACE-inhibitor after anthracycline (AAA) study of cardiac dysfunction in long-term pediatric cancer survivors. Am Heart J 142: 577-585, 2001.

2000

Gaynor JW, Wernovsky G, Rychik J, Rome JJ, DeCampli WM, Spray TL  : Outcome following single stage repair of coarctation with ventricular septal defect. Eur J Cardiothorac Surg 18: 62-67, 2000.Mahle WT, Rychik J, Rome JJ : Clinical significance of pulmonary arteriovenous malformations after staging bidirectional cavopulmonary anastomosis. Am J Cardiol 86: 239-241, 2000.

Mahle WT, Tian ZY, Cohen MS, Howell L, Johnson M, Cromblehomme T, Adzick NS, Rychik J : Echocardiographic evaluation of the fetus with congenital cystic adenomatoid malformation (CCAM). Ultrasound Obstet Gynecol 16: 620-624, 2000.

Rychik J, Spray TL, Gaynor JW, Wernovsky G  : Assessment of pulmonary-to-systemic flow ratio after first stage palliation for hypoplastic left heart syndrome: development of a new index using Doppler echocardiography. J Thorac Cardiovasc Surg 120: 81-87, 2000.

Yang SG, Novello R, Nicolson S, Steven J, Gaynor JW, Spray TL, Rychik J : Evaluation of ventricular septal defect repair using intra-operative transesophageal echocardiography: frequency and significance of residual defects in infants and children. Echocardiography  17: 681-684, 2000.

1999

Banks BA, Seri I, Ischiropoulis H, Merrill J, Rychik J, Ballard RA  : Improved oxygenation with inhaled nitric oxide in severe bronchopulmonary dysplasia. Pediatrics 103: 610-618, 1999.

Fogel MA, Weinberg PM, Rychik J, Hubbard A, Jacobs ML, Spray TL, Haselgrove J : Caval contribution to flow in the branch pulmonary arteries of Fontan patients using a novel application of magnetic resonance presaturation pulse. Circulation 99: 1215-1221, 1999.

Gaynor JW, Collins MH, Rychik J, Gaughan JP, Spray TL : Long-term outcome of infants with single ventricle and total anomalous pulmonary venous connection.  J Thorac Cardiovasc Surg  117: 506-514, 1999.

Lee HR, Montenegro LM, Nicolson SC, Gaynor JW, Spray TL, Rychik J  : Usefulness of intra-operative trans-esophageal echocardiography in predicting the degree of mitral regurgitation secondary to atrioventricular defect in children. Am J Cardiol 83: 750-753, 1999.

Marino B, Wernovsky G, Rychik J, Bockoven JR, Godinez R, Spray TL : Early results of the Ross procedure in simple and complex left heart disease. Circulation 100((surgical suppl)): II 162 - II 166, 1999.

McDonnell BE, Raff GW, Gaynor JW, Rychik J, Godinez RI, DeCampli WM, Spray TL  : Outcome following repair of tetralogy of Fallot with absent pulmonary valve. Ann Thorac Surg 67: 1391-1395, 1999.

Rychik J, Rome JJ, Collins M, Spray TL : Hypoplastic left heart syndrome with intact atrial septum: atrial anatomy, lung histopathology, and outcome. J Am Coll Cardiol 34: 554-560, 1999.

Schwartz IP, Bernbaum JC, Rychik J, Grunstein M, D'Agostino J, Polin RA : Pulmonary hypertension in children following ECMO therapy and repair of congenital diaphragmatic hernia. J of Perinatol 19: 220-226, 1999.

1998

Donofrio MT, Jacobs ML, Spray TL, Cohen MS, Hogarty AN, Rychik J: : Early changes in preload, afterload, and systolic ventricular function after superior cavopulmonary connection  Ann Thorac Surg 65: 503-508, 1998.

Fogel MA, Weinberg PM, Gupta KB, Rychik J, Hubbard A, Hoffman EA, Haselgrove J  : Mechanics of the single left ventricle: a study in ventricular-ventricular interaction II. Circulation 98: 330-338, 1998.

Mahle WT, Rychik J, Weinberg PM, Cohen M   : Growth characteristics of the aortic arch after the Norwood operation. J Am Coll Cardiol 32: 1951-1954, 1998.

Mahle WT, Weinberg PM, Rychik J  : Can echocardiography predict the presence or absence of endocardial fibroelastosis in infants under one year of age with left ventricular outflow obstruction?  Am J Cardiol 82: 122-124, 1998.

Rychik J, Levy H, Gaynor JW, DeCampli WD, Spray TL  : Outcome after operations for pulmonary atresia with intact ventricular septum. J Thorac Cardiovasc Surg 116: 924-931, 1998.

1997

Donofrio MT, Jacobs ML, Rychik J  : Tetralogy of Fallot with absent pulmonary valve leaflet syndrome: echocardiographic morphometric features of the right sided structures and their relationship to presentation and outcome. J Am Soc Echocardiogr  10: 556-561, 1997.

Fogel MA, Rychik J, Vetter J, Donofrio MT, Jacobs ML : Effects of volume unloading surgery on coronary flow dynamics in patients with aortic atresia. J Thorac Cardiovasc Surg  113: 718-727, 1997.

Fogel MA, Weinberg PM, Hoydu A, Hubbard A, Rychik J, Jacobs ML, Fellows KE, Haselgrove J  : The effects of surgical reconstruction on velocity and flow profiles in the aorta using magnetic resonance blood tagging. Ann Thorac Surg  63: 1691-1700, 1997.

Fogel MA, Weinberg PM, Hoydu A, Hubbard A, Rychik J, Jacobs ML, Fellows KE, Haselgrove J: : The nature of flow in the systemic venous pathway in Fontan patients utilizing magnetic resonance imaging. J Thorac Cardiovasc Surg 114: 1032-1041, 1997.

Rychik J, Fogel MA, Donofrio MT, Goldmuntz E, Cohen MS, Spray TL, Jacobs ML : Comparison of patterns of pulmonary venous blood flow in the functional single ventricle heart after operative aorto-pulmonary shunt - vs - superior cavo-pulmonary shunt. Am J Cardiol  80: 922-926, 1997.

Rychik J, Jacobs ML : Intra-operative transesophageal echocardiographic imaging of intra-pulmonary tunnel repair for anomalous left coronary artery originating from the pulmonary artery. Echocardiography 14: 33-38, 1997.

Rychik J, Marchlinski F, Sweeten T, Berul C, Bhat M, Burke C, Vetter VL: Transcatheter radiofrequency ablation of congenital junctional ectopic tachycardia in infancy.  Peds Cardiol  18: 447-450, 1997.

Rychik J, Rome JJ, Jacobs ML: Late surgical fenestration for complications after Fontan Operation. Circulation  96: 33-36, 1997.

Rychik J, Tian ZY, Fogel MA, Joshi V, Rose NC, Jacobs ML : The single ventricle heart in the fetus: accuracy of prenatal diagnosis and outcome. J of Perinatol 17: 183-188, 1997.

Shah M, Rychik J, Fogel MA, Murphy JD, Jacobs ML: Pulmonary arterio-venous malformations after superior cavo-pulmonary connection: resolution following surgical inclusion of hepatic venous blood into the pulmonary circulation. Ann Thorac Surg 63: 960-963, 1997.

1996

Cohen M, Jacobs ML, Weinberg PM, Rychik J : Morphometric analysis of unbalanced common atrioventricular canal using two-dimensional echocardiography.  J Am Coll Cardiol 28: 1017-1023, 1996.

Jacobs ML, Rychik J, Byrum CJ, Norwood WI  : Protein losing enteropathy after the Fontan operation: resolution after baffle fenestration. Ann Thorac Surg 61: 206-208, 1996.

Jacobs ML, Rychik J, Rome JJ, Apostolopoulou S, Pizarro C, Murphy JD, Norwood WI : Early reduction of the volume work of the single ventricle: the Hemi-Fontan operation. Ann Thorac Surg  62: 456-461, 1996.

Rychik J, Gullquist SD, Jacobs ML, Norwood WI   : Doppler analysis of flow patterns in the ductus arteriosus of infants with single ventricle and critical aortic outflow obstruction. J Am Soc Echocardiography 9: 166-173, 1996.

Rychik J, Tian ZY : Quantitative assessment of myocardial tissue velocities in normal children using Doppler tissue imaging. Am J Cardiol 77: 1254-1257, 1996.

Rychik J.  : Aortic stenosis or atresia with associated hypoplasia of the left ventricle: Imaging before and after reconstructive surgery. Echocardiography 13: 325-336, 1996.

1995

Donofrio MT, Jacobs ML, Norwood WI, Rychik J: Early changes in ventricular septal defect size in the single ventricle after volume unloading surgery   J Am Coll Cardiol 26: 1008-1015, 1995.

Jacobs ML, Chin AJ, Rychik J, Steven JM, Nicolson SC, Norwood WI: Interrupted aortic arch: impact of subaortic stenosis on management and outcome. Circulation  92((suppl II)): II-128 - II-131, 1995.

Jacobs ML, Rychik J, Donofrio MT, Steven J, Nicolson S, Murphy JD, Norwood WI : Avoidance of subaortic obstruction in staged management of single ventricle. Ann Thorac Surg 60: S543-545, 1995.

Jacobs ML, Rychik J, Murphy JD, Nicolson SC, Steven JM, Norwood WI : Results of Norwood operation for lesions other than hypoplastic left heart syndrome. J Thorac Cardiovasc Surg 110: 1555-1561,  1995.

Rychik J, Jacobs ML, Norwood WI: Acute changes in left ventricular geometry after volume reduction surgery.   Ann Thorac Surg 60: 1267-1274, 1995.

1994

Rychik J, Jacobs ML, Norwood WI: Early changes in ventricular geometry and ventricular septal defect size following "Rastelli" operation or intra-ventricular baffle repair for conotruncal anomaly: a cause for development of subaortic stenosis. Circulation 90(part 2): II-13 - II-19, 1994.

1991

Rychik J, Murdison KA, Chin AJ, Norwood WI: Surgical management of severe aortic outflow obstruction in lesions other than the hypoplastic left heart syndrome: use of a pulmonary artery-to-aorta anastomosis. J Am Coll Cardiol  18((3)): 809-816, 1991.

Rychik J, Norwood WI, Chin AJ: Doppler color flow mapping assessment of residual shunt after closure of large ventricular septal defect.  Circulation 84((suppl III)): III-153 -III-161, 1991.

Rychik J, Piccoli DA, Barber G: Usefulness of corticosteroid therapy for protein-losing enteropathy after the Fontan procedure. Am J Cardiol  68(8): 819-821, 1991.

 

Books

2021

Fogel MA, Rychik J: The Single Ventricle Heart  Wiley Publishing  2021.

2019

Rychik J, Cohen MS, Rossano J, Chen J. : Progress in Pediatric Cardiology Special Issue - Highlights of the CHOP Cardiology 2019 Conference. Elsevier Publishing 2019.

2012

Gleason MM, Rychik J, Shaddy RE: Pediatric Practice: Cardiology. McGraw-Hill. New York 2012.



Rychik J & Tian Z: Fetal Cardiovascular Imaging: A Disease Based Approach. WB Saunders, Elsevier Inc. Philadelphia, 2012.

2006

Rychik J. Guest Editor, Progress in Pediatric Cardiology: Advances in Fetal Cardiovascular Disease, Volume 22, No 1, May 2006.

2002

Rychik J & Wernovsky G (eds): Hypoplastic Left Heart Syndrome. Kluwer Academic Publishers, Boston, Dordecht, London, publication - November 2002.

Chapters
2020

Edelson J, Rychik J. : The Fontan circulation. Chapter in Moss & Adams, Heart Disease in Infants, Children and Adolescents 10th Edition, in press , 2020.

2018

Ho D, Rychik J. : "The Placenta in Congenital Heart Disease" in Paediatric Cardiology   Elsevier Publishing. Anderson RH, Baker EJ, Redington A, Rigby ML, Penny D, Wernovsky G. (eds.). 4th Edition. (in press), 2018.

2012

Rychik J  : The fetal cardiovascular examination; Prenatal practice care model and delivery of the fetus with cardiovascular disease; Counseling and support for the family carrying a fetus with cardiovascular disease. Rychik J and Tian Z, Fetal Cardiovascular Imaging: A Disease Based Approach.  WB Saunders, Elsevier Inc. Philadelphia  (eds.). 2012.

Rychik J: Congenital absence of aortic valve leaflets; Hypoplastic left heart syndrome; Aortic stenosis and mitral valve dysplasia syndrome; Echo bright spot in the heart; Ectopia cordis; Diverticulum or aneurysm of the heart. Rychik J and Tian Z, Fetal Cardiovascular Imaging: A Disease Based Approach. WB Saunders, Elsevier Inc, Philadelphia, 2012.

Rychik J: Conjoined twins; Fetal cardiomyopathy; Abnormalities of the ductus venosus; Agenesis of the ductus venosus; Twin twin transfusion syndrome; Sacrococcygeal teratoma; Cerebral arterial malformation; Pulmonary arteriovenous malformation; Congenital cystic adenomatoid malformation; Congenital diaphragmatic hernia. Rychik J and Tian Z, Fetal Cardiovascular Imaging: A Disease Based Approach.  WB Saunders, Elsevier Inc. Philadelphia, 2012.

O'Connor MJ, Goldberg DJ, Rychik J : Single ventricle congenital heart disease. Pediatric Practice Cardiology. Gleason MM, Rychik J, Shaddy RE (eds.). McGraw Hill  2012.

2011

Thacker D, Rychik J    : Heart failure in the fetus. Pediatric Heart Failure. Shaddy R (eds.). 2011.

2009

Goldberg D, Rychik J   : Hypoplastic Left Heart Syndrome. Pediatric and Congenital Echocardiography Textbook. Geva, Lai, Cohen. Mertens (eds.). 2009.

Szwast A, Natarajan S, Rychik J  : Fetal Echocardiography. Pediatric Echocardiography Textbook  Eidem, O'Leary, Cetta, Lippincott  (eds.). 2009.

2008

Szwast A & Rychik J. Fetal Cardiology in Paediatric Cardiology, 2nd Edition, Eds: Anderson, Wernovsky, Elsevier 2008.

Rychik J. The twin-twin transfusion syndrome: evolving concepts. In Neonatology Questions and Controversies, Editors: Kleinman & Seri, Elsevier 2008.

Shillingford A, Rychik J. Central nervous system outcomes in congenital heart disease. In Fetal Cardiology, 2nd Edition, Eds: Yagel, Silverman, Gembruch 2008.

2006

Rychik J. “Evaluation of the fetal cardiovascular system” in Prenatal Diagnosis, Eds. Mark Evans, Mark Paul Johnson, Yuval Yaron, Arie Drugan. McGraw-Hill 2006, pp 653-671.

Rychik J. Fetal cardiovascular disease, in “Pediatric Cardiology: The Requisites in Pediatrics,” Ed Victoria L. Vetter, M.D., Mosby/Elsevier 2006, pp 223-237.

2005

Rychik J. “Echocardiography and Doppler Ultrasound,” in Ventricular Function and Blood Flow in Congenital Heart Disease, Ed. M.A. Fogel, Futura Publishing, Mount Kisco, New York 2005.

2004

Rychik J & Cohen MS: “Echocardiography in the neonatal intensive care unit” in Avery’s Diseases of the Newborn; Taesch W, Ballard R, Gleason C (eds), Harcourt Publishers, 2004 pp 802-811.

2002

Rychik J: “Complications after Fontan operation: Protein losing enteropathy and thromboembolic disease”, in Rychik J & Wernovsky G (eds): The Hypoplastic Left Heart Syndrome. Kluwer Academic Publishers, Boston, Dordecht, London, publication - Fall 2002.

Rychik J: “Non-invasive imaging in the hypoplastic left heart syndrome” in, Rychik J & Wernovsky G (eds): The Hypoplastic Left Heart Syndrome. Kluwer Academic Publishers, Boston, Dordecht, London, publication - Fall 2002.

2001

Rychik J: “Utility of fetal echocardiography during invasive intrauterine fetal therapy” in Frontiers in Fetal Health, July 2001, Vol 3, No 7.

1998

Rychik J: “The right ventricle supporting the systemic circulation: short and middle term follow up” Chapter 22, in Redington AN, Brawn WJ, Deanfield JE, Anderson RH (Ed): The Right Heart in Congenital Heart Disease, Greenwich Medical Media, London, England, 1998, pp 157-161.

Rychik J: “Management of protein-losing enteropathy after the Fontan procedure” in Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual 1998;1:15-21.

Rychik J: “Diagnostic imaging modalities for congenital heart disease /echocardiographic evaluation,” Chapter 63, in Kaiser LR, Kron IL, Spray TL (Ed): Mastery of Cardiothoracic Surgery, Little, Brown and Company, Boston, MA, 1998, pp 602-620.

1995

Rychik J: "Murmurs," in Clinical Handbook of Pediatrics, Williams & Wilkins, Baltimore, Maryland, 1995.

Posters and Presentations

Invited Lectures
2020

Rychik J. "Fetal cardiac imaging and therapeutics: where should we be in 2030?" - On the Horizon Session, American Society of Echocardiography Virtual Scientific Sessions 2020. Aug 2020.

Rychik J. "Cardiovascular manifestations of the monochorionic pregnancy" "Early fetal ECHO for the MFM Sonographer" "Counseling of the family following prenatal detection of fetal heart disease" "Anomalies of the left side of the heart: hypoplastic left heart syndrome" "Conotruncal anomalies: Transposition of the great arteries" - at the 12th Philadelphia Prenatal Conference [on-line Webinar format]. June 2020.

Rychik J. "The hard talk, seeing how best to speak to…The young couple following prenatal diagnosis of CHD" - 23rd Annual Update on Pediatric and Congenital Cardiovascular Disease: Cardiology 2020, Yacht and Beach Club, Orlando, FL. Feb 2020.

Rychik J. "When there is only one pump: diagnosis, management and outcomes for the fetus with single ventricle heart disease" and "Neurocognitive outcomes in congenital heart disease and their origins in prenatal life" - at the Society for Maternal Fetal Medicine Postgraduate Course 2020, Gaylord Hotel, Dallas, Texas. Feb 2020.

Rychik J. "Heart care before birth: diagnosis and management of fetal cardiovascular disease" - guest speaker, annual meeting of the New Jersey Fetal Medicine Society, Forsgate Country Club, Monroe Township, New Jersey. Feb 2020.

2019

Rychik J. "Cross disciplinary care of the single ventricle from fetus to adult" - at Collaboration in Cardiac Care, Sydney Children's Hospital, Westmead, Sydney, Australia. Dec 2019.

Rychik J. "Principles of fetal counseling," "Fetal diagnosis and management of hypoplastic left heart syndrome," "Complex fetal heart cases and what we learned," 'Cardiovascular aspects of monochorionic pregnancy"- Focus on the Fetus 2019: A course on fetal echocardiography, diagnosis of fetal anomalies and fetal treatment, CHOP, Philadelphia, PA. Nov 2019.

Rychik J. "Relationship between foramen ovale restriction and flow characteristics of the ductus arteriosus in fetal transposition of the great arteries" - at the ISUOG Conference 2019, Berlin, Germany. Oct 2019.

Rychik J. "The Fontan conundrum: setting the stage" - at The Heart Summitt: Management of the Failing Fontan , A Look into the Future, Herma Heart Institute, Children's Hospital of Wisconsin, Milwaukee, WI. Oct 2019.

Rychik J. "The basics of fetal echocardiography" "Heart care before birth" "Hypoplastic left heart syndrome" - at the Society for Pediatric Radiology 2019 Fetal Imaging Course, CHOP, Philadelphia, PA. Sept 2019.

Rychik J. "The twin-twin transfusion syndrome" "Ebstein's anomaly and tricuspid valve dysplasia in the fetus" - 6th Annual Multimodlaity Cardiovascular Imaging Update 2019, Mexico City, Mexico. July 2019.

Rychik J. "Decision making for the fetus & neonate: regionalized care for the highest risk" - 30th Scientific Sessions of the American Society of Echocardiography, Portland, OR. June 2019.

Rychik J. "Anomalies of the left side of the heart", "The maternal fetal environment and the placenta in congenital heart disease", "Heart Failure in the fetus: conditions that cause it and tools for characterization", "Cardiovascular manifestations of monochorionic twin pregnancy" at the 11th Philadelphia Prenatal Conference, Sonesta Philadelphia Downtown Hotel, Philadelphia PA. June 2019.

Rychik J. "Maternal hyperoxygenation: testing and treatment" and "The maternal-fetal environment and the future of prenatal health care" - at the 10th Annual Symposium: Innovations in Imaging in Congenital Heart Disease, Mt Sinai Hospital, New York, New York. May 2019.

Rychik J. "Life with half a heart: Physiological and clinical manifestations of the Fontan circulation - a perspective" at the 6th International Conference on Clinical and Engineering Frontiers in Pediatric and Congenital Heart Disease Symposium, Philadelphia, PA. May 2019.

Rychik J. "Heart care before birth: novel diagnostic and therapeutic strategies for the fetus with cardiovascular disease," "Life with only half a heart: defining the problem and the many consequences of a Fontan circulation," at the 6th Krakow Educational Workshop on Congenital Heart Disease, Krakow, Poland. May 2019.

Rychik J. "Life with half a heart: understanding single ventricle congenital heart disease and its consequences" - Pediatric Grand Rounds, Lucille Packard Children's Hospital, Stanford University, Palo Alto, CA. Mar 2019.

Rychik J. "Challenges and Opportunities: The Fontan Conundrums" and "Principles of Fetal Therapy: Can we Modify the Course of Nature Before Birth" at the 22nd Annual Update on Pediatric and Congenital Cardiovascular Disease Conference, Huntington Beach, CA. Feb 2019.

Awards and Honors

2018, Thomas Graham Lecture, Vanderbilt University

2017, Dan McNamara Visiting Professor & Lectureship, Texas Children's Hospital, Houston, TX

2017, Arthur Moss Family Honorary Lectureship, Pediatric Cardiology, UCLA/Mattel Children's Hospital

2016, Annual Zuberbuhler Lecturer and Visiting Professor, Pittsburgh Children's Hospital (May 2016)

2016, 35th Katkov-Lundeen Visiting Professor in Pediatric Cardiology and Cardiovascular Surgery, The Children's Heart Clinic

2014, Cazden Memorial Lecturer Award in Pediatric Cardiology – Oregon Health Sciences University, Doernbecher Children’s Hospital, Portland, OR

2014, Chai Lifeline, Physician Community Service Award

2013, The Children’s Heart Foundation “Smart Heart” Award for Innovative Research

2013, Founder’s Award, American Society of Echocardiography

2012-2015, Philadelphia Magazine – “Top Docs” designation, pediatric cardiology

2011, David J. Driscoll Visiting Professor and Lectureship, Mayo Clinic, Rochester, MN

2010, Richard L. Day Teaching Award in Pediatrics, Alumni Association, Downstate Medical Center

2009-present, Robert S. and Dolores Harrington Endowed Chair in Pediatric Cardiology, The Children’s Hospital of Philadelphia

2009, Feigenbaum Lecturer, American Society of Echocardiography Scientific Sessions 

2009, Feigenbaum Lecturer, American Society of Echocardiography Scientific Sessions 

2007, Award for best oral abstract presentation, session on fetal cardiology, International Society for Ultrasound in Obstetrics and Gynecology (Florence, Italy; October 9, 2007)

2007, “Best Doctors” designation

2001, Philadelphia Magazine – “Top Docs” designation

1989, ACC/ Syntex Continuing Medical Education Award

Editorial and Academic Positions

Editorial Positions

2020-present, Associate Editor, International Journal of Cardiology - Congenital Heart Disease
2010–present, Editorial Board, World Journal for Pediatric and Congenital Heart Surgery 
2008–present, Editorial Advisory Board, Progress in Pediatric Cardiology
2006–present, Editorial Board, Congenital Heart Disease: Clinical Studies from Fetus to Adulthood
2005–present, Editorial Board, Fetal Diagnosis and Therapy

Manuscript Reviewer

Amercian Heart Journal
American Journal of Cardiology
Anesthesia and Analgesia
American Journal of Obstetircs and Gynecology
Annals of Throacic Surgery
Cardiology in the Young
Circulation
Echocardiography
Journal of the American College of Cardiology
Journal of the American Society of Echocardiography
Journal of Thoracic and Cardiovascular Surgery
New England Journal of Medicine
Mayo Clinic Proceedings
Pediatric Cardiology

Academic and Institutional Committees

2018-present, Chair, CHOPPA Network Development Physician Advisory Group Committee
2012-present, Cardiac Center Operations and Planning Committee
2007-present, Cardiac Center Technology and Information Systems Committee
2002-present, Cardiac Center Strategic Business and Planning Committee

Leadership and Memberships

Memberships in Professional Organizations
International

2007-present, Member, International Society of Ultrasound in Obstetrics and Gynecology
2003-present,  Member, International Fetal Medicine and Surgery Society

National

2018-present, Fontan Outcomes Network
 - 2020-present, Co-Director
 - 2018-present, Fontan Outcome Network Design Group, Chair
2017-present, AHA Scientific Statement Writing Group Committee
2015-present, Fetal Heart Society
 - 2015-present, Executive Committee, Secretary
1993-present,  Fellow, American College of Cardiology
1993-present,  Member, American Society of Echocardiography
1989-present, Member, American Heart Association/Council on Cardiovascular Disease in the Young