Mariarita Santi, MD, PhD

female silhouette icon
Mariarita Santi, MD, PhD, is an attending physician in the Division of Neuropathology at Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Modena University Medical School, Modena, Italy


Anatomic Pathology - George Washington University, Washington, DC


Neuropathology - Armed Forces Institute of Pathology, Washington, DC

Board Certification

Anatomic Pathology – American Board of Pathology
Neuropathology – American Board of Pathology

Graduate Degree

PhD in Pharmacology - Modena University, Modena, Italy

Titles and Academic Titles

Attending Physician, Division of Neuropathology

Associate Professor of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania

Departments and Services




Talaat K, Rothman J, Cohen J, Santi M, Rorke-Adams L, Choi J, Guzman M, Zimmerman R, Nallasamy S, Brucker, Klion A Nichols KE. Fatal lymphocytic vasculitis involving the central nervous system in X-linked lymphoproliferative disease patients without evidence of Epstein-Barr virus infection. Pediatric Blood and Cancer. 2009 Dec;53(6):1120-3.


Thorarinsdottir HK, Santi M, McCarter R, Rushing EJ, Cornelison R, Jales A,MacDonald TJ. PDGFR and PTEN association with childhood glioma. Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas. Clin Cancer Res. 2008;14:3386-3394 PMID: 18519768.

Scheithauer BW, Santi M, Richter ER, Belman B and Rushing EJ. Diffuse ganglioneuromatosis and plexiform neurofibroma of the urinary bladder: Report of a pediatric example and literature review. Human Pathology 2008, 39 PMID: 18656232.


Santi M, Kadom N, Vezina G, Rushing EJ. Undiagnosed medulloblastoma presenting as fatal hemorrhage in a 14-year-old boy: case report and review of the literature. Child Nerv Syst. 2007 23:799-805.


Santi M, Quezado M, Ronchetti R, Rushing EJ. Analysis of Chromosome 7 in Adult and Pediatric Ependymomas using Chromogenic In Situ Hybridization. J Neur Oncol. 2005;72:25-28.

Rushing EJ, Olsen C, Mena H, Rueda ME, Lee YS, Keating RF, Packer RJ, Santi M. Central Nervous System Meningiomas in the first two decades of life: Clinicopathologic analysis of 87 cases. Journal of Neurosurgery .2005;103:489-495.