Ashley E. Sobel Leonard, MD, PhD

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)
MD - Duke University School of Medicine – Durham, NC
PhD - Duke University School of Medicine – Durham, NC
Resident Physician, University of Washington Affiliated Hospitals, Seattle, WA
Fellow, Division of Infectious Diseases
Infectious disease, viral ecology and evolution, global health and pandemic preparedness.
Manus, M., Bloomfield, G., Sobel Leonard, A., Guidera, L., Samson, D., Nunn, C. (2018). High Prevalence of Hypertension in an Agricultural Village in Madagascar. PLoS One. https://doi.org/10.1371/journal.pone.0201616
Sobel Leonard, A., Weissman, D., Greenbaum, B., Ghedin, E., & Koelle, K. (2017). Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus Bottleneck size inference from pathogen deep-sequencing data. Journal of Virology.91(14). pii: e00171-17. doi: 10.1128/JVI.00171-17.
Sobel Leonard, A., Mcclain, M. T. K., Smith, G. J. D., Wentworth, D., Rebecca, A., Lin, X., … Christopher, J. R. (2017). The Effective Rate of Influenza Reassortment is Limited During Human Infection. Plos Pathogens, 1–27. http://doi.org/10.1371/journal.ppat.1006203
Sobel Leonard, A., McClain, M. T., Smith, G. J. D., Wentworth, D. E., Halpin, R. A., Lin, X., … Koelle, K. (2016). Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification. Journal of Virology, 90(24), 11247–11258. http://doi.org/10.1128/JVI.01657-16
Leonard, J. A., Sobel Leonard, A., Chang, D. T., Edwards, S., Lu, J., Scholle, S., … Tan, Y. M. (2016). Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays. Environmental Science and Technology, 50(11), 5961–5971. http://doi.org/10.1021/acs.est.6b00374
Abou-Donia, M. B., Siracuse, B., Gupta, N., & Sobel Leonard, A*. (2016). Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review. Critical Reviews in Toxicology, 8444(November), 1–31. http://doi.org/10.1080/10408444.2016.1220916
*Incorrectly listed as Ashley Sobel Sokol
Gwinn, W. M., Johnson, B. T., Kirwan, S. M., Sobel, A. E., Abraham, S. N., Gunn, M. D., & Staats, H. F. (2013). A comparison of non-toxin vaccine adjuvants for their ability to enhance the immunogenicity of nasally-administered anthrax recombinant protective antigen. Vaccine, 31(11), 1480–1489. http://doi.org/10.1016/j.vaccine.2013.01.012
Staats, H. F., Fielhauer, J. R., Thompson, A. L., Tripp, A. A., Sobel, A. E., Maddaloni, M., … Pascual, D. W. (2011). Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits. PloS One, 6(1), e16532. http://doi.org/10.1371/journal.pone.0016532
2015, Travel bursary to attend Viral Genomics and Evolution Conference in Hinxton, UK
2015, Mitchell Meritorious Travel award to attend Viral Genomics and Evolution Conference in Hinxton, UK
2014, cholarship to attend Summer Institute in Statistics and Modeling Infectious Diseases, Seattle. USA
2013, Travel award to attend Disease Dynamics conference, Vancouver, CV
2012, Scholarship to attend Ecology of Infectious Disease workshop, Ann Arbor, MI, USA
2008, William Griffith Service Award for Commitment to the Global Community
2007, Phi Beta Kappa, inducted Fall
2008, Phi Lambda Upsilon, inducted Spring
2015, Bass Connections Research team, Durham, NC
2010, AIDS Orphan Education Trust, Jinja, Uganda
2009-2010, Infectious Disease Interest Group, Durham, NC