Rajeev Subramanyam, MBBS, MD, MS

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Rajeev Subramanyam, MBBS, MD, MS, is an anesthesiologist with the Department of Anesthesiology and Critical Care Medicine and Associate Division Chief for Quality and Safety, General Anesthesiology, at Children's Hospital of Philadelphia.

Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MBBS - Bangalore Medical College, Bangalore University, India

Internship

Medicine - Bangalore Medical College, Bangalore University, India

Residency

Anesthesiology - Post Graduate Institute of Medical Education and Research, Chandigarh, India

Fellowship

Ambulatory Anesthesiology - University of Toronto, Canada

Pediatric Anesthesiology - Hospital for Sick Children, Toronto, Canada

Advanced Fellowship - Quality Improvement, Cincinnati Children’s Hospital Medical Center, OH

Board Certification

Anesthesiology
Pediatric Anesthesiology

Graduate Degree

MS in Clinical and Translational Research - University of Cincinnati, OH

Titles and Academic Titles

Anesthesiologist

Chair, Quality and Safety Committee, General Anesthesiology

Director, Quality Improvement, Radiology Anesthesia Sedation Service

Associate Division Chief for Quality and Safety, General Anesthesiology

Associate Professor of Clinical Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Sleep disordered breathing
Smoking and secondhand smoke exposure
Quality improvement and patient safety

Publications

Papers

2017

Subramanyam, R., Ledbetter, K., Fleck, R., Mahmoud, M. Congenital pulmonary airway malformation. Anesthesiology 127;382:2017.

2016

Subramanyam, R., Yeramaneni, S., Hossain, M.D., Anneken, A., Varughese, A. Perioperative respiratory adverse events in pediatric ambulatory anesthesia: Development and validation of a risk prediction tool. Anesthesia & Analgesia 122: 1578-1585, 2016.

Subramanyam, R., Fleck, R., McAuliffe, J., Radhakrishnan, R., Jung, D.E., Patino, M., Mahmoud, M. Airway morphology in down syndrome patients under Dexmedetomidine sedation. Brazilian Journal of Anesthesiology 66: 388-394, 2016.

Buck, D., Subramanyam, R., Varughese, A. A quality improvement project to reduce the intraoperative use of single dose fentanyl vials across multiple patients at a pediatric institution. Pediatric Anesthesia 26:92-101, 2016.

Kandil, A., Subramanyam, R., Ishman, S., Shott, S., Hossain, M.D., Tewari, A., Mahmoud, M. Comparison of the combination of dexmedetomidine and ketamine to propofol or propofol/sevoflurane for drug-induced sleep endoscopy in children. Pediatric Anesthesia 26:742-751, 2016.

Subramanyam, R., Mahmoud, M., Buck, D., Varughese, A. Infusion medication error reduction by two-person verification: a quality improvement initiative. Pediatrics 138: pii: e20154413, 2016.

2015

Subramanyam, R., Cudilo, E.M., Hossain, M.D., McAulifee, J., Wu, J., Patino, M., Gunter, J., Mahmoud, M. To pretreat or not to pretreat: Prophylactic anticholinergic administration prior to dexmedetomidine in pediatric imaging. Anesthesia & Analgesia 121:479-485, 2015.

2014

Subramanyam, R., Chidambaran, V., Ding, L., Sadhasivam, S. Anesthesia and opioid related malpractice claims in the United States: LexisNexis Claims database – 1984 to 2012. Pediatric Anesthesia 24:412-20, 2014.

Subramanyam, R., Varughese, A., Kurth, C.D., Eckman, M.H. Costeffectiveness of Intravenous Acetaminophen for Pediatric Tonsillectomy. Pediatric Anesthesia 24:467-475, 2014.

2013

Subramanyam, R., Varughese, A., Willging, J.P., Sadhasivam, S. Future of pediatric tonsillectomy and perioperative outcomes. International Journal of Pediatric Otorhinolaryngology 77:194-199, 2013.

2012

Mehta, V., Subramanyam, R., Shapiro, C.M., Chung, F. Health effects of identifying patients with undiagnosed obstructive sleep apnea in the preoperative clinic: a follow-up study. Canadian Journal of Anaesthesia 59: 544-555, 2012.

Chung, F., Subramanyam, R., Liao, P., Sasaki, E., Shapiro, C., Sun, Y. A higher score of STOP-Bang questionnaire predicts more severe obstructive sleep apnea. British Journal of Anaesthesia 108:768-75, 2012. (Highly Cited Article).

2011

Zhang, L., Seet, E., Mehta, V., Subramanyam, R., Saravanan, P.A. Oropharyngeal leak pressure of LMA SupremeTM at different intracuff pressures - A Randomized Controlled. Canadian Journal of Anaesthesia 58:624-629, 2011.

Subramanyam, R., Vaishnav, V., Chan, V.W.S., Brown-Shreves, D., Brull, R. Lateral vs. Medial Needle Approach for ultrasound-guided supraclavicular block: A Randomized Controlled Trial. Regional Anesthesia and Pain Medicine 36:387-392, 2011.

2010

Seet, E., Subramanyam, R., Firoz, T., Yousaf, F., Wong, J., Wong, D.T., Chung, F. Safety and efficacy of LMA SupremeTM Versus LMA ProSealTM - A Randomized Controlled Trial. European Journal of Anaesthesiology 27:602-607, 2010.

Seet, E., Yousaf, F., Gupta, S., Subramanyam, R., Wong, D., Chung, F. Use of manometry for laryngeal mask airway reduces postoperative pharyngolaryngeal adverse events. Anesthesiology 112:652-657, 2010.

Parrington, S.J., O’Donnell, D., Chan, V.W.S., Brown-Shreves, D., Subramanyam, R., Qu, M., Brull, R. Dexamethasone added to mepivacaine prolongs the duration of analgesia following supraclavicular brachial plexus blockade. Regional Anesthesia Pain Medicine 35:422-426, 2010.

Harjeet., Sahni, D., Batra, Y.K., Rakesh, S.V., Subramanyam, R. Anatomical dimensions of larynx, epiglottis and cricoid cartilage in fetuses and their relationship with crown rump length. Surgical and Radiologic Anatomy 32:675-681, 2010.

Batra, Y.K., Rakesh, S.V., Panda, N.B., Lokesh, V.C., Subramanyam, R. Intrathecal clonidine decreases sedation requirements during spinal anesthesia in infants. Pediatric Anesthesia 20:625-632, 2010.

2009

Kumar, M., Batra, Y.K., Panda, N.B., Subramanyam, R., Nagi, O.N. Tramadol added to bupivacaine does not prolong analgesia of continuous psoas compartment block. Pain Practice 9:43-50, 2009.

Batra, Y.K., Subramanayam, R., Panda, N.B., Lokesh, V.C., Rao, K.L.N. Study of different doses of intrathecal neostigmine with bupivacaine for infants undergoing lower abdominal and urogenital procedures. Acta Anaesthesiologica Scandinavica 53:470-475, 2009.

Aggarwal, A., Kaur, H., Batra, Y.K., Aggarwal, A.K., Subramanyam, R., Sahni, D. Anatomic consideration of caudal epidural space: A cadaver study. Clinical Anatomy 22:730-737, 2009.

2008

Harjeet., Saini, D., Batra, Y.K., Subramanyam, R. Anatomical dimensions of trachea, main bronchi, subcarinal and bronchial an gles in fetuses measuredex vivo. Pediatric Anesthesia 18:1029-1034, 2008.

Muralikrishna, T., Panda, N.B., Batra, Y.K., Subramanyam, R. Combination of low doses of intrathecal ketamine and midazolam with bupivacaine improves postoperative analgesia in o rthopedic surgery. European Journal of Anaesthesiology 25:299-306, 2008.

Batra, Y.K., Lokesh, V.C., Panda, N.B., Subramanyam, R., Rao,  L.N. Dose ranging study of intrathecal fentanyl in infants undergoing lower abdominal and urological procedures. Pediatric Anesthesia 18:613-619, 2008.

Batra, Y.K., Mahajan, R., Kumar, S., Subramanyam, R., Dhillon, M.S. Dose ranging study of intra-articular midazolam for pain relief following knee arthroscopy. Anesthesia & Analgesia 107:669-672, 2008.

2007

Subramanyam, R., Batra, Y.K., Panda, N.B., Kumar, M., Nagi, O.N. Combined continuous “3-in-1” and sciatic nerve blocks provide improved postoperative analgesia with no correlation to catheter tip location after unilateral total knee arthroplasty. Journal of Arthroplasty 22:1181-1186, 2007.

Books

2015

Subramanyam, R., Sadhasivam, S. Critical Incidents: Hypocarbia. Young and Olutoye: Handbook of Essential Topics and Critical Incidents in Pediatric Anesthesia. Cambridge university press 2015, United Kingdom, 2015.

Subramanyam, R., Sadhasivam, S. Critical Incidents:Hypercarbia. Young and Olutoye: Handbook of Essential Topics and Critical Incidents in Pediatric Anesthesia. Cambridge university press 2015, United Kingdom, 2015.

Subramanyam, R., Sadhasivam, S. Plastic Surgery: Craniofacial Reconstruction. Young and Olutoye: Handbook of Essential Topics and Critical Incidents in Pediatric Anesthesia. Cambridge university press 2015, United Kingdom, 2015.

Subramanyam, R., Sadhasivam, S. Plastic Surgery: General Considerations. Young and Olutoye: Handbook of Essential Topics and Critical Incidents in Pediatric Anesthesia. Cambridge university press 2015, United Kingdom, 2015.

2014

Engelhardt, T., Crawford, M., Subramanyam, R., Lerrman, J. Plastics and reconstructive surgery. In Cote and Lerrman Textbook of Pediatric Anesthesia. Expert Consult 5th ed, 2014.

Posters and Presentations

2017

Cooper E, Varughese A, Mahmoud M, Hill L, Glynn S, Subramanyam R. Presence of upper respiratory infection appears to not be associated with an increase in adverse respiratory events after tonsillectomy. Society for Pediatric Anesthesia, 2017. (Presented at the Society for Pediatric Anesthesia Meetings, Austin 2017). Notes: Oral presentation

Campion M, Subramanyam R, Aronson L, Ding L, Helmrath M, Inge T, Mecoli M. Predictors of ICU Admission Following Laparoscopic Gastric Sleeve (LSG) in Morbidly Obese Adolescents: A retrospective study. Society for Pediatric Anesthesia, 2017. (Presented at the Society for Pediatric Anesthesia Meetings, Austin 2017). Notes: Poster presentation.

Subramanyam R, Ding L, Sadhasivam S, Hill L, Glynn S, Willging P, Tsevat J, Eckman M, Varughese . Development and validation of a prediction tool for adverse post anesthetic outcomes in pediatric tonsillectomy. Society for Pediatric Anesthesia, 2017. (Presented at the Society for Pediatric Anesthesia Meetings, Austin 2017). Notes: Oral presentation.

2016

Subramanyam, R., Eckman, M., Sadhasivam, S., Ding, L., Spruance, K., Chidambaran, V. Cost-Effectiveness of Intravenous Acetaminophen/Ketorolac in Adolescents Undergoing Spine Fusion. American Society of Anesthesiologists, 2016. (Presented at the American Society of Anesthesiologists Meetings, Chicago, 2016). Notes: Poster presentation.

Adler, E., Burkley, M., Mahmoud, M., Gordon, D., Subramanyam, R. Retrospective review of airway management of congenital pulmonary airway malformation. American Society of Anesthesiologists, 2016. (Presented at the American Society of Anesthesiologists Meetings, Chicago, 2016). Notes: Poster presentation.

Subramanyam, R., Mahmoud, M., Curtwright, L., Buczak, K., Varughese, A. Reducing Infusion Pump Programming Medication Errors using Quality Improvement Methodology. Society for Pediatric Anesthesia, 2016. (Presented at the Society for Pediatric Anesthesia Meetings, Colorado Springs 2016). Notes: Oral presentation.

Burkley, M., Adler, E., Gordon, D., Subramanyam, R. Retrospective review of anesthetic management of congenital pulmonary airway malformation. Society for Pediatric Anesthesia, 2016. (Presented at the Society for Pediatric Anesthesia Meetings, Colorado Springs 2016). Notes: Poster presentation.

Patino, M., Burell, C., Ding, L., Subramanyam, R., Mahmoud, M. Outcomes of children with obstructive sleep apnea undergoing outpatient diagnostic radiologic procedures under dexmedetomidine sedation. Society for Pediatric Anesthesia, 2016. (Presented at the Society for Pediatric Anesthesia Meetings, Colorado Springs 2016). Notes: Poster presentation.

2015

Subramanyam, R., Cudilo, E., Hossain, M.M., Patino, M., Gunter, J, Mahmoud, M. To Pretreat or Not to Pretreat That is the Question: Bradycardia during Dexmedetomidine Sedation in Children. American Society of Anesthesiology, 2014. (Presented at the American Society of Anesthesiologists Meetings, New Orleans 2015). Notes: Poster presentation.

Cudilo, E., Varughese, A., Mahmoud, M., Subramanyam, R. Intraoperative Pulmonary Edema and Postoperative Lactic Acidosis during Pediatric Spine Surgery. American Society of Anesthesiology, 2014. (Presented at the American Society of Anesthesiologists Meetings, New Orleans 2015). Notes: Poster presentation.

Cudilo, E., Mahmoud, M., Varughese, A., Gordon, D., Das, B., Patino, M., Fleck, R., Sjoblom, M., Bryant, M., Subramanyam, R. Absent epiglottis in a 14-month-old undergoing airway imaging with dexmedetomidine sedation. American Society of Anesthesiology, 2014. (Presented at the American Society of Anesthesiologists Meetings, New Orleans 2015). Notes: Poster presentation.

Subramanyam, R., Mahmoud, M., Curtwright, L., Buczak, K., Varughese, A. Reducing Infusion Pump Programming Medication Errors using Quality Improvement Methodology. American Society of Anesthesiology, 2015. Presented at the American Society of Anesthesiologists Meetings, San Diego 2015). Notes: Oral presentation.

Cudilo, E.M., Mahmoud, M., Sharma, A., Subramanyam, R. Meta-analysis of Dexmedetomidine Compared to Propofol for Pediatric Non-operating Room Anesthesia. American Society of Anesthesiology, 2015. (Presented at the American Society of Anesthesiologists Meetings, San Diego 2015). Notes: Poster presentation.

Kandil, A., Subramanyam, R., Tewari, A., Ishman, S., Shott, S., Mahmoud, M. Anesthetic management of Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Children with Obstructive Sleep Apnea. American Society of Anesthesiology, 2015. (Presented at the American Society of Anesthesiologists Meetings, San Diego 2015). Notes: Poster presentation.

Subramanyam, R., Varughese, A., Laugel, J., Stallworth, K., Mahmoud, M. Sedation and general anesthesia adverse events in preterm and term infants undergoing radiologic imaging. Society for Pediatric Anesthesia, 2015. (Presented at the Society for Pediatric Anesthesia Meetings, Phoenix, 2015). Notes: Poster presentation.

Invited Lectures

2017

Subramanyam R. March, 2017 “Pediatric Tonsillectomy Outcomes” – Society for Pediatric Anesthesia, Austin, Texas

Subramanyam R. January, 2017 “Clinical Effectiveness Research in Pediatrics” – Children’s Hospital of Philadelphia, Pennsylvania

Subramanyam R. January, 2017 “Moderator” Fellow Journal Club, Children’s Hospital of Philadelphia, Pennsylvania

2016

Subramanyam R. October, 2016 “Pediatric Obstructive Sleep Apnea” – Ohio Society of Anesthesiologists, Columbus, Ohio

Subramanyam R. April, 2016 “Pediatric Outcomes” – Networking Anesthesia World Convention, New York, New York

2015

Subramanyam R. October, 2015 “Quality Improvement and Patient Safety in Pediatric Anesthesia” – Post Graduate Institute of Medical Education and Research, India

Awards and Honors

2017, Selected in Top 25 best papers ever published in British Journal of Anesthesia on World Anesthesia Day

2016, Clinical Investigator, American Society of Anesthesiologists

2013, First prize winner, American Academy of Pediatrics

2011, Chief Fellow, Hospital for Sick Children, Toronto, Canada

2009, White Mountain Award, Society for Ambulatory Anesthesia

2009, Travel Award, Society for Ambulatory Anesthesia

2008, Medal for best graduating resident, Postgraduate Institute of Medical Education & Research, India

2008, M.N.A.M.S (Hon.) Member of National Academy of Medical Sciences, India

2007, Young Anesthesiologist, Indian Society of Anesthesiologists

Editorial and Academic Positions

Editorial Positions

2017-present, Reviewer, Journal of Anesthesia

2016-present, Reviewer, Acta Otolaryngologica

2016-present, Reviewer, International Archives of Clinical Anesthesia Research

2016-present, Reviewer, Pediatrics

2016-present, Reviewer, Vascular Health and Risk Management

2015-present, Reviewer, BMC Anesthesiology

2015-present, Reviewer, ClinicoEconomics and Outcomes Research

2015-present, Reviewer, Indian Journal of Anesthesia

2015-present, Reviewer, Journal of Anesthesiology

2015-present, Reviewer, Journal of Anaesthesiology and Clinical Pharmacology

2015-present, Reviewer, Journal of Pain Research

2015-present, Reviewer, Local and Regional Anesthesia

2014-2017, Editorial Board Member, Ambulatory Anesthesia

2014-2017, Reviewer, Ambulatory Anesthesia

2014-present, Reviewer, Canadian Journal of Anaesthesia

2014-present, Reviewer, Pediatric Anesthesia

Leadership and Memberships

Memberships in Professional Organizations

International

2004-present, Indian Society of Anesthesiologists

National

2014-present, Society for Anesthesia and Sleep Medicine,  Gold Patron Member

 - 2017-present, Chair, Pediatric Committee

 - 2016-2017, Co-Chair, Pediatric Committee 

 - 2015-present, News Letter Committee

2011-present, Society for Pediatric Anesthesia

2010-present, American Society of Anesthesiologists

 - 2015-present, Outcomes and Database Committee