Charlotte Z. Woods-Hill, MD

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Charlotte Z. Woods-Hill, MD, is an attending physician in the Pediatric Sepsis Program and the Division of Critical Care Medicine at Children's Hospital of Philadelphia.

Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)


Dr. Woods-Hill graduated from the University of Miami with a double major in biology and religious studies, before attending the University of South Florida College of Medicine. She completed residency training in general pediatrics at Harvard University/Boston University’s Boston Combined Residency Program in 2013. After fellowship training in pediatric critical care medicine at the Johns Hopkins Children’s Center, including specialized certification from the Armstrong Patient Safety Institute’s Analytics Leadership in Patient Safety program, she joined the pediatric critical care medicine faculty at Children's Hospital of Philadelphia in 2016. She is a leader in critical care sepsis quality improvement, working to improve sepsis recognition and standardize treatment algorithms through a combination of EMR-based alerts and multidisciplinary bedside huddles.

As the division’s physician champion for central-line associated bloodstream infection harm prevention, Dr. Woods-Hill is working to develop and pilot a predictive model to better identify high-risk patients and reduce infection rates. She is a co-investigator and site principal investigator on the AHRQ-funded Bright STAR Collaborative, a multicenter investigation into the impact of diagnostic stewardship for bloodstream infections in the PICU on antibiotic use and antibiotic resistance. Currently she is enrolled in the Masters of Science in Health Policy program at the University of Pennsylvania supported by an NIH T32 training grant, as well as an associate fellow at the Leonard Davis Institute of Health Economics, where her focus is on translating health policy and health systems-based investigations into reductions in preventable patient harm in the critical care setting. 

Education and Training

Medical School

MD - University of South Florida Morsani College of Medicine, Tampa, FL


Pediatrics - Boston Combined Residency Program, Boston Children’s Hospital, Boston, MA


Pediatrics - Boston Combined Residency Program, Boston Children’s Hospital, Boston, MA


Pediatric Critical Care - Johns Hopkins Children’s Center, Baltimore, MD

Board Certification

Pediatric Critical Care Medicine – American Board of Pediatrics
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Attending Physician

Departments and Services




Woods-Hill CZ, Colantuoni EA, Koontz DW, Voskertchian A, Xie A, Thurm C, Miller MR, Fackler JC, Milstone AM, Bright STAR Authorship Group: Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient OutcomesResults of the Bright STAR Collaborative. JAMA Pediatrics May 2022 Notes: doi:10.1001/jamapediatrics.2022.1024.

Kathleen Chiotos, MD, MSCE Julie Fitzgerald, MD, MSCE Molly Hayes, PharmD; Hannah Dashefsky, BSN, RN; Talene Metjian, PharmD; Charlotte Woods-Hill, MD, MSHP; Lauren Biedron, BSN, RN; Hannah Stinson, MD; Brandon Ku, MD; Sheila Robbins Tighe, CRNP; Scott Weiss, MD, MSCE; Fran Balamuth, MD, MSCE; Emily Schriver, MS; Jeffrey S. Gerber, MD, MSCE : Improving Vancomycin Stewardship in Critically Ill Children  Pediatrics 2022 Apr 1;149(4):e2021052165, April 2022.

Weber MD, Conlon T, Woods-Hill C, Watts S, Eileen N, Traynor D, Zhang B, Davis D, Himebauch A: Retrospective Assessment of Patient and Catheter Characteristics Associated With Malpositioned Central Venous Catheters in Pediatric Patients. Pediatric Critical Care Medicine 23(3): 192-200, March 2022.

Woods-Hill CZ, Xie A, Lin J, Wolfe HA, Plattner AS, Malone S, Chiotos K, Szymczak J: Numbers and narratives: how qualitative methods can strengthen the science of paediatric antimicrobial stewardship. JAC-Antimicrobial Resistance 4(1): dlab195, February 2022 Notes:


Woods-Hill CZ, Koontz DW, Voskertchian A, Xie A, Shea J, Miller MR, Fackler JC, Milstone AM; Bright Star Consensus Authorship Group.: Consensus Recommendations for Blood Culture Use in Critically Ill Children Using a Modified Delphi Approach. Pediatric Critical Care Medicine April 2021.

Woods-Hill CZ, Papili K, Nelson E, Lipinski K, Shea J, Beidas R, Lane-Fall M.: Harnessing implementation science to optimize harm prevention in critically ill children: a pilot study of bedside nurse CLABSI bundle performance in the pediatric intensive care unit American Journal of Infection Control 49(3): 345-351, March 2021.


Hoops K, Fackler JC, King A, Colantuoni E, Milstone A, Woods-Hill CZ: How good is our diagnostic intuition? Clinician prediction of bacteremia in critically ill children  BMC Medical Informatics and Decision Making 20(1): 144, July 2020.

Xie A, Koontz DW, Voskertchian A, Fackler JC, Milstone AM, Woods-Hill CZ: Survey-based work system assessment to facilitate large-scale dissemination of healthcare quality improvement programs. QI Methodology 5(2): e288, May 2020.

Woods-Hill CZ, Srinivasan L, Schriver E, Haj-Hassan T, Bezpalko O, Sammons JS : Novel risk factors for central-line associated bloodstream infections in critically ill children. Infection Control and Hospital Epidemiology  41(1): 67-72, Jan 2020.

Woods-Hill CZ, Koontz DW, King AF, Voskertchian A, Colantuoni EA, Miller MR, Fackler JC, Bonafide CP, Milstone AM, Xie A; and the Bright StarAuthorship group: Practices, perceptions, and attitudes in the evaluation of critically ill children for bacteremia a national survey Pediatric Critical Care Medicine 21(1): e23-e29, Jan 2020.


Sick-Samuels, A; Woods-Hill CZ; Fackler JC, Tamma P, Klaus SA, Colantuoni E, Milstone AM. : Association of a Blood Culture Utilization Intervention on Antibiotic Use in a Pediatric Intensive Care Unit. Infection Control and Hospital Epidemiology  40(4): 482-484, April 2019.

Xie A, Woods-Hill CZ, King AF, Enos-Graves H, Ascenzi J, Gurses AP, Klaus SA, Fackler JC, Milstone AM: Work System Assessment to Facilitate the Dissemination of a Quality Improvement Program for Optimizing Blood Culture Use: A Case Study Using a Human Factors Engineering Approach. Journal of the Pediatric Infectious Diseases Society 8(1): 39-45, March 2019.

Conlon TW, Himebauch AS, Cahill AM, Kraus BM, Madu CR, Weber MD, Czajka CA, Baker RL, Brinkley TM, Washington MD, Frey AM, Nelson EM, Jefferies CT, Woods-Hill CZ, Wolfe HA, Davis DH: Development and implementation of a bedside peripherally inserted central catheter service in a PICU. Pediatric Critical Care Medicine 20(1): 71-78, January 2019.


Woods-Hill CZ, Lee L, Xie A, King AF, Voskertchian A, Klaus SA, Smith M, Miller MR, Colantuoni EA, Fackler JC, Milstone AM: Dissemination of a novel framework to improve blood culture use in three pediatric intensive care units. Pediatric Quality and Safety 3(5): e112, September/October 2018.


Xie A, Woods-Hill CZ, King AF, et al. Work system assessment to facilitate the dissemination of a quality improvement program for optimizing blood culture use: a case study using a human factors engineering approach. J Pediatric Infect Dis Soc. 2017. Epub ahead of print. doi: 10.1093/jpids/pix097

Woods-Hill CZ, Fackler J, McMillan KN, Ascenzi J, Martinez DA, Toerper MF, Voskertchian A, Colantuoni E, Klaus SA, Levin S, Milstone AM: Association of a clinical practice guideline with blood culture use in critically ill children. JAMA Pediatrics 171(2): 157-164, February 2017.



Chiotos K, Lee G, Sydney G, Wolfe HA, Blumenthal J, Stinson H, McGowan N, Harab J, Traynor D, Dudhia A, Piccione J, Burke J, Doll A, Keim G, Woods-Hill C, Jennings M, Harris R, Gerber JS: Indications for tracheal aspirate culture collection and their association with diagnosis of ventilator-associated infection. Society for Healthcare Epidemiology of America Spring Conference April 2021 Notes: Poster Presentation at the Society for Healthcare Epidemiology of America Spring Conference, (Virtual).

Stinson H, Dashefsky H, Chiotos K, Woods-Hill C, Weiss SL, Fitzgerald JC : Care delivery related to sepsis in a SARS-CoV-2 Pediatric Intensive Care Unit. Critical Care Medicine 49(1): 150, January 2021 Notes: Research Snapshot Presentation at the 50th Critical Care Congress, February, 2021 (Virtual).


Weber M, Conlon TW, Woods-Hill CZ, Crowe R, Watts S, Glau C, Davis DA, Himebauch AS: Prevalence of central venous catheter malpositioning in critically ill children. Critical Care Medicine 48(1): 480, January 2020 Notes: Research Snapshot Presentation at 49th Critical Care Congress, February 2020, Orlando, FL.


Woods-Hill CZ, Weber M, Conlon TW, Himebauch AS, Nelson E, Morris K, Davis DH, Cahill AM, Priestley MA: Safety and efficacy of antibiotic coated PICC lines in PICU patients - a pilot study. Pediatric Academic Societies (PAS) 2019 Meeting April 2019 Notes: Poster Presentation at the PAS Meeting, April 2019, Baltimore, MD.

Woods-Hill CZ, Xie A, King A, Koontz D, Voskertchian A, Colantuoni E, Miller M, Fackler J, Milstone A, and the Bright Star Collaborative authorship group : A national survey of blood culture practices to inform a diagnostic stewardship initiative. Critical Care Medicine 47(1): 668, January 2019 Notes: Poster Presentation at the 48th Critical Care Congress, February 2019, San Diego, CA.

Morris, K, Nelson E, Woods-Hill, CZ: PICU CLABSI stand-down education: Back to basics. Critical Care Medicine 47(1): 669, January 2019 Notes: Poster presentation at 48th Critical Care Congress, February 2019, San Diego, CA.

Chiotos K, Biedron L, Fitzgerald J, Robbins-Tighe S, Weiss SL, Woods-Hill C: Sepsis huddles in the PICU: Understanding the impact on timely antibiotics, perceptions, and barriers. Critical Care Medicine 47(1): 820, January 2019 Notes: Poster Presentation at 48th Critical Care Congress, February 2019, San Diego, CA.

Awards and Honors

2020, Junior Faculty Honor Roll for Resident Education, The Children’s Hospital of Philadelphia

2016, Johns Hopkins Hospital High Value Research Symposium, 2nd place Best Trainee Abstract - Improving Blood Culture Utilization in Critically Ill Children, Johns Hopkins Bloomberg Children's Center, Baltimore, MD

2013, Medical Student Teaching Award, Harvard Medical School Pediatric Clerkship

2013, Senior Resident Address, Boston Combined Residency Program graduation

2010,  Dean’s Award for Excellence, USF College of Medicine Valedictorian

2010,  Department of Pediatrics Award, USF College of Medicine

2010,  Christopher P. Phelps Award for Excellence in Anatomy

2010, Award for Excellence in Medical Neuroscience

2010,  Outstanding Student in Principles of Medical Immunology and Infectious Disease

2010, Outstanding Student in Molecular Medicine

2010, Award for Excellence in Pharmacology

2009,  Alpha Omega Alpha honor society

2009, Arnold P. Gold Humanism in Medicine Society

2009, Don L. Smith Charter Class Scholarship, USF College of Medicine

2009, 2008, 2007, USF College of Medicine Merit Scholarship

2006, Theta Alpha Kappa Award for Outstanding Achievement in Department of Religious Studies, University of Miami

2006, Best Senior Thesis, Department of Women’s Studies, University of Miami

2005, Phi Beta Kappa honor society, University of Miami

2005, Gamma Sigma Alpha National Greek Honor Society; Gamma Sigma Alpha Award, Highest New Member Scholarship

Editorial and Academic Positions

Academic and Institutional Committees

2016-present, PICU/PCU Patient Safety and Quality Improvement Committee, Department of Critical Care Medicine

2016-present, PICU Sepsis Quality Improvement

2016-present, Critical Care Physician Lead, Central Line Associated Bloodstream Infections Committee