Four gene therapy experts from Children’s Hospital of Philadelphia (CHOP) were interviewed as part of a comprehensive article in Philadelphia Magazine about cell and gene therapy. The article explores gene therapy as a powerful tool for treating diseases, profiling leading researchers in the Philadelphia region who have made strides in bringing these experimental treatments to patients.
The article features Beverly L. Davidson, PhD, Director of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics and Chief Scientific Strategy Officer, who spoke about the state of the field, as a leading gene therapy researcher for several decades; Lindsey A. George, MD, a hematologist and director of clinical in vivo gene therapy at CHOP, who discussed her role as the lead investigator in a gene therapy clinical trial for hemophilia B; Denise E. Sabatino, PhD, a hematologist and gene therapy researcher, who provided expertise on gene therapy for hemophilia, as well as the challenges and unknowns of gene therapy; and Stephan A. Grupp, MD, PhD, Section Chief of the Cellular Therapy and Transplant Section, Director of the Cancer Immunotherapy Program, and Medical Director of the Cell and Gene Therapy Laboratory, who discussed gene editing and his role in a clinical trial using CRISPR to treat sickle cell disease. The article also profiles Bill Maurits, who has hemophilia B and was treated by Dr. George at CHOP and calls the gene therapy treatment “life-changing.”
Read more about CHOP’s gene therapy research in Philadelphia Magazine.