Comprehensive Care for Congenital Musculoskeletal Anomalies

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In Utero Insights

Congenital musculoskeletal and limb disorders can pose long-term challenges and cause life-threatening symptoms. Prenatal detection helps us identify the specific anomaly and the pathology of each condition and allows for early involvement from a multidisciplinary team.

At Children's Hospital of Philadelphia's Center for Fetal Diagnosis & Treatment, patients have access to some of the most experienced pediatric orthopaedic surgeons in the world. Our orthopaedic specialists have a deep understanding of the correlation between prenatal diagnosis and postnatal severity. They collaborate with our fetal imaging and maternal-fetal medicine specialists, obstetricians, and geneticists to accurately diagnose congenital musculoskeletal conditions before birth and counsel families on prognosis and treatment options after birth.

Our orthopaedic team has experience treating even the rarest musculoskeletal conditions on a regular basis and has developed innovative techniques and devices for the treatment of many conditions. These specialists work closely with other specialists throughout our Hospital to provide comprehensive, family-centered care, often into adulthood.

Our Winter 2018 issue of In Utero Insider provides a detailed look at the resources and expertise we offer patients whose pregnancies present with congenital musculoskeletal anomalies.

Read more articles on this topic.

Select References

Antiel RM, Riley JS, Cahill PJ, Campbell RM, Waqar L, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Management and outcomes of scoliosis in children with congenital diaphragmatic hernia. J Pediatr Surg. 2016;51(12):1921-1925.

Coleman BG, Langer JE, Horii SC. The diagnostic features of spina bifida: the role of ultrasound. Fetal Diagn Ther. 2015;37(3):179-196.

Defrancesco CJ, Shah DK, Rogers BH, Shah AS. (2017) The epidemiology of brachial plexus birth palsy in the United States: Declining incidence and evolving risk factors. [Published online ahead of print Oct. 9 2017] J Pediatr Orthop.

Gholson JJ, Buckwalter JA, Shah AS. Thirty-five year clinical and radiographic follow-up of preaxial polydactyly reconstruction: Level 4 evidence. J Hand Surg Am. 2017;42(9):S24.

Iorio J, Orlando G, Diefenbach C, Gaughan JP, Samdani AF, Pahys JM, Betz RR, Cahill PJ. Serial casting for infantile idiopathic scoliosis: Radiographic outcomes and factors associated with response to treatment. J Pediatr Orthop. 2017;37(5):311-316.

Karlin JG, Roth MK, Patil V, Cordell D, Trevino H, Simmons J, Campbell RM, Joshi AP. Management of thoracic insufficiency syndrome in patients with Jarcho-Levin syndrome using VEPTRs (vertical expandable prosthetic titanium ribs). J Bone Joint Surg Am. 2014;96(21):e181.

LaGreca J, Flynn T, Cahill PJ, Samdani A, Vitale MG, El-Hawary R, Smith JT, Phillips JH, Flynn JM, Glotzbecker M, Garg S; Children's Spine Study Group. Patients without intraoperative neuromonitoring (IONM) alerts during VEPTR implantation did not sustain neurological injury during subsequent routine expansions: A retrospective multicenter cohort study. J Pediatr Orthop. 2017;37(8):e619-e624.

Mistovich RJ, Jacobs LJ, Campbell RM, Spiegel DA, Flynn JM, Baldwin KD. Infection control in pediatric spinal deformity surgery: A systematic and critical analysis review. JBJS Rev. 2017;5(5):e3.

Nossov SB, Curatolo E, Campbell RM, Mayer OH, Garg S, Cahill PJ. Children's Spine Study Group. VEPTR: Are we reducing respiratory assistance requirements? [Published online ahead of print April 10, 2017] J Pediatr Orthop.  

Tong Y, Udupa JK, Odhner D, Wu C, Zhao Y, McDonough JM, Capraro A, Torigian DA, Campbell RM. Interactive iterative relative fuzzy connectedness lung segmentation on thoracic 4D dynamic MR images. Proc. SPIE. Vol. 10137, Medical Imaging 2017: Biomedical Applications in Molecular, Structural and Functional Imaging, 1013723 (13 March 2017).

Tong Y, Udupa JK, Ciesielski KC, Wu C, McDonough JM, Mong DA, Campbell RM Jr. Retrospective 4D MR image construction from free-breathing slice acquisitions: A novel graph-based approach. Med Image Anal. 2017;35:345-359.

Victoria T, Epelman M, Coleman BG, Horii S, Oliver ER, Mahboubi S, Khalek N, Kasperski S, Edgar JC, Jaramillo D. Low-dose fetal CT in the prenatal evaluation of skeletal dysplasias and other severe skeletal abnormalities. AJR Am J Roentgenol. 2013;200(5):989-1000.

Screenshot of CFDT tour video

Tour our Fetal Center

Watch this video tour to learn what to expect at your first visit to the Wood Center for Fetal Diagnosis and Treatment.

Pregnant Mom and Child

What to Expect

From the moment of referral through delivery and postnatal care, your family can expect a supportive experience when you come to us with a diagnosis of a birth defect.