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Gene therapy may slow loss of motor function in ALS, Penn and CHOP research finds
CHOP and Penn researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.
Children’s Hospital of Philadelphia and St. Jude Researchers Find Genetic Ancestry Influences How Gene Mutations Impact Cancer Prognosis in Patients With T-cell Acute Lymphoblastic Leukemia
Investigators at Children’s Hospital of Philadelphia, St. Jude Children’s Research Hospital, Dana Farber Cancer Institute, and the Children’s Oncology Group, unveiled for the first time that changes in certain genes affect an aggressive cancer, T-cell acute lymphoblastic leukemia, differently depending on genetic ancestry.
Children's Hospital of Philadelphia Receives Grant to Study Noninvasive Technique for Detecting Malaria Via Breathalyzer
Taking one important step toward addressing the malaria crisis that impacts millions of patients globally each year, Children’s Hospital of Philadelphia (CHOP) has received a $1 million grant from the Gates Foundation to study a new, non-invasive technique involving chemicals in the breath to help identify individuals infected with malarial parasites.
Independence Blue Cross and Children’s Hospital of Philadelphia sign new agreement that reflects their joint commitment to children's health in the region
Independence Blue Cross and Children’s Hospital of Philadelphia have signed a new, multi-year agreement ensuring that families in the region with IBX health plans can access high-quality pediatric care at CHOP.
From the Media: FDA and CDC Recommend Pause in Use of Live-Attenuated Chikungunya Vaccine in Adults 60 and Older
Find out about a May 2025 pause in use of live-attenuated chikungunya virus vaccine in adults 60 years and older.
Children’s Hospital of Philadelphia Researchers Demonstrate that Doula and Midwife Support for Mothers in the Neonatal Intensive Care Unit Improves Postpartum Care
In a new study, researchers at Children’s Hospital of Philadelphia (CHOP) showed that partnering with doulas and midwives to support mothers with newborns in the Neonatal Intensive Care Unit (NICU) significantly improves access to timely, essential health services during a critical period of care.
CHOP Hosts Cure Sickle Cell Walk & Family Fun Day Presented by West Pharmaceutical Services, Raising More Than $242,000 for Research and Care
Children’s Hospital of Philadelphia (CHOP) hosted the Cure Sickle Cell Walk & Family Fun Day presented by West Pharmaceutical Services on Saturday, June7. It was a morning of walking, cheering and celebrating sickle cell warriors and their families at Citizens Bank Park. The event, which included a ceremonial walk to honor those with sickle cell disease, along with fun activities for the whole family, raised more than $242,000 for sickle cell disease research and patient care.
Children’s Hospital of Philadelphia Researchers Spotlight Adults with Hypoplastic Left Heart Syndrome (HLHS) Thriving Without Transplants
CHOP researchers reported long-term clinical outcomes for the largest single center cohort of individuals who underwent complex reconstructive surgery for hypoplastic left heart syndrome as newborns. In this cohort, more than 30% survived without a transplant to at least 35 years of age.
Vaccine Resources: Infographics, Toolkits, Webinars, and the Vaccine Integrity Project
Check out resources to support conversations about whooping cough and measles. Take a crash course in podcasting, and more!
News & Views — Shared Clinical Decision-Making: What It Is and Why It Matters
Find out about the history of shared clinical decision-making (SCDM) recommendations and their intended use in clinical practice.