Orthopaedic Clinical Research

Research on spine disorders

  • Operative treatment of high-grade spondylolisthesis in children
  • Prospective study of scoliosis in children with cerebral palsy
  • Aneurysmal bone cyst (ABC) of the spine
  • Scoliosis Outcomes Database
  • Managing complex spinal deformities
  • Spondylolysis and conservative treatment: is radiographic healing necessary for full recovery?
  • Do children with scoliosis and low socioeconomic status present at a later stage?
  • Bracing adolescent idiopathic scoliosis
  • Prospective study of Scheuermann's kyphosis
  • A retrospective analysis of the utility of plain X-rays in the management of low back pain
  • Cost analysis of post-operative care in pediatric spine patients
  • Dual rod instrumentation with limited fusion for the treatment of progressive early-onset scoliosis
  • Operative delay with the use of intravenous Vancomycin in orthopaedic spine surgery
  • Safety of Vancomycin powder in pediatric spine patients
  • The Chest Wall and Spine Deformity Registry
  • Use of the O-arm® intraoperative computerized tomography scanner in pediatric spinal surgery
  • Pediatric surgical site infections following spine procedures
  • Pediatric spine and thorax geometry and pulmonary function
  • Acquired torticollis in children: the role of dynamic axial rotational CT scans in the diagnosis of atlanto-axial rotatory displacement (subluxation and fixation)
  • Minimize Implants, Maximize Outcomes clinical trial 

Early-onset scoliosis, thoracic insufficiency syndrome and VEPTR research

  • Neuromonitoring and growing rods/VEPTR (potential prospective clinical trial)
  • VEPTR implantation to treat children with early-onset scoliosis without rib abnormalities: a prospective multi-center study
  • Pediatric spine and thorax geometry and pulmonary function
  • The Virtual Growing Child 

Research on musculoskeletal tumors and growths

  • Functional outcome and complications after reconstruction with an expandable endoprosthesis in children with bony sarcomas
  • Identification and characterization of genes and molecular mechanisms causing multiple hereditary osteochondroma (MHO) and related bone disorders
  • Center of Research Translation in Multiple Hereditary Exostoses (MHE)
  • A novel diagnostic MR imaging sign for osteoid osteoma
  • The use of intraoperative CT in osteoid osteomas and osteoblastoma treatment
  • A retrospective review of bone and soft-tissue sarcomas
  • Chondroblastoma (multi-center)
  • Treatment of nonossifying fibromas using percutaneous curettage, intramedullary decompression and grafting
  • Thoracic osteochondroma
  • Upper extremity tumors in children
  • Aggressive fibromatosis in children: a review of outcome management at CHOP
  • Fibrous dysplasia/shepherd’s crook deformity
  • Jaffe-Campanacci syndrome/neurofibromatosis type 1 clinical overlap
  • The treatment of benign lesions of the proximal femur in children: a new classification with corresponding treatment implications

Research on hip disorders

  • Retrospective slipped capital femoral epiphysis (SCFE) study: prophylactic pinning of the contralateral hip
  • Hip reconstruction in cerebral palsy: an analysis of complications and outcomes
  • Range of motion of the hip in children: what is the norm?
  • Pediatric hip disorders clinical registry and sample repository
  • Long-term outcomes after in situ pinning for slipped capital femoral epiphysis (SCFE)
  • What is the natural history, prognosis, and proper guidelines of management in infants with developmental dysplasia of the hip (DDH)

Foot, knee and leg disorder research

  • Intercondylar shelf angle in the normal pediatric knee: what is normal?
  • All-epiphyseal anterior cruciate ligament (ACL) reconstruction: ideal placement of the femoral tunnel
  • A natural history of pseudoarthrosis of the tibia
  • Meniscal tears in pediatric athletes: treatment and outcomes
  • Results of arthroscopic treatment of discoid meniscus
  • MRI measurements of normal and ACL-torn knees in skeletally immature patients
  • Degeneration of the knee joint in skeletally immature patients diagnosed with a tear of the anterior cruciate ligament: is there harm in delay of treatment?
  • Bilateral ACL tears in children and adolescents
  • ACL recovery
  • Correlation between isokinetic strength testing and functional testing in adolescent athletes following ACL reconstruction
  • ACL injury prevention program
  • The treatment of benign lesions of the proximal femur in children: a new classification with corresponding treatment implications
  • Determining the standard for clubfoot
  • Rehabilitation timeline following all epiphyseal anterior cruciate ligament (ACL) reconstruction
  • Transphyseal versus independent tunnel placement in ACL reconstruction in skeletally immature patients: is it safe to assume we are comparing apples-to-apples?
  • Clubfoot treatment: retrospective review of treatment with Ponseti method and variants
  • Sports medicine outcomes: Multi-center ACL Revision Study (MARS)
  • Epiphyseodesis of contralateral limb in case of endoprosthetic replacement for various malignant conditions of lower limb
  • Accessory navicular

Research on hand and arm disorders

  • Acute compartment syndrome of the upper extremity in children: diagnosis, management and outcomes
  • Referral patterns of emergent hand transfers to a tertiary care center
  • Incidence of MRSA infections after hand surgery
  • Shoulder instability and dislocations in adolescents: evaluation and treatment
  • Long-term follow-up of gunshot wounds to the hand or upper extremity in children
  • Pink pulseless hand (prospective study)
  • Diagnostic utility of MRI scans in pediatric wrist injury
  • Unstable supracondylar humerus fractures: experience with the “suprone” technique
  • Non-operative treatment compared with plate fixation of displaced midshaft clavicle fractures: a prospective evaluation
  • Supracondylar humerus fractures in children younger than three years
  • Overview of Monteggia fractures/dislocations
  • Validation and integrated use of a simulated pediatric distal radius fracture reduction model
  • Functional outcomes of displaced distal radius fractures in children
  • Factors affecting outcome of supracondylar fractures
  • An analysis of T-condylar fractures in children and adolescents
  • Radial neck fracture outcomes of patients treated at CHOP
  • Radial neck fractures in children
  • Medial epicondyle fractures in throwing and other overhead athletes

Safety and infection control research

  • Musculoskeletal staph aureus infections in children: a cohort comparison of methicillin-resistant and methicillin-sensitive strains
  • Retrospective review of intravenous Vancomycin prophylaxis in pediatric orthopaedic patients
  • An investigation into orthopaedic methicillin-resistant staphylococcus aureus (caMRSA) infection in children
  • Outcomes and efficacy of multi-modal anesthesia use in children
  • Leukocyte esterase strip study
  • Safety of Vancomycin powder in pediatric spine patients

Research on other orthopaedic topics

  • Pain, function and quality of life in patients with neuromuscular disorders
  • The Virtual Growing Child
  • Relationship of osteochondritis dissecans classification to healing and functional outcomes
  • Osteochondritis dissecans in children
  • Healing patterns of osteochondritis dissecans lesions on radiographs
  • Osteochondritis Dissecans of the Knee: Disease, Treatment and Outcome Registry
  • Retro versus trans articular drilling for juvenile osteochondritis dissecans of the knee: a multi-center, randomized controlled study
  • Inter/intra-rater reliability in measuring size of osteochondritis dissecans lesions on plain radiographs
  • Long-term follow up of treatment for avascular necrosis (AVN)
  • Osteochondritis dissecans (OCD) cost analysis

Reviewed by: Division of Orthopaedics

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