Autism Integrated Care Program Clinical Studies

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Linguistic Markers of Autism Spectrum Disorder

The goal of this study is to learn more about the ways autism spectrum disorder (ASD) is expressed in a large sample of individuals with and without ASD.  Children ages of 6-17, without ASD, are eligible to  participate.  Participation involves 1 study visit that lasts approximately 2-3 and involves behavioral and cognitive testing.  Parents will be asked to complete questionnaires about their children. Families will be compensated for their time. IRB 13-010514

Infant Brain Imaging Study

This research study focuses on how the brain develops differently in infants with autism spectrum disorder (ASD) compared to typically developing children. The goal of the study is to identify very early brain features that may be characteristic of autism. This information may help improve methods of early detection and intervention for infants who may be at risk for this disorder.

We are seeking to enroll families who have infants 3 months old or younger and who have an older sibling who has autism or who is typically developing. Babies will come to CHOP at 3 and 24 months of age, as well as two other time points in between, to receive developmental evaluations and magnetic resonance imaging (MRI) scans. Parents will receive comprehensive evaluation reports at no cost and will be compensated for their family's time and travel. IRB 07-005689

SPARK: Simons Foundation Powering Autism Research for Knowledge

The mission of SPARK is to ignite research at an unprecedented scale to improve lives by advancing our understanding of autism. To join this national autism research cohort, individuals with a professional diagnosis of autism and their biological family members will be asked to share information about their medical and family history, as well as provide a DNA sample. Please contact the Center for Autism Research for more information at 1-866-570-6524 or autism@email.chop.edu.

Motor Synchrony Study

The purpose of this study is to understand how motor function- the way we move our faces and bodies- impactssocial communication. We are seeking adolescents ages 12-17 with or without ASD or a mixed psychological diagnosis (ADD, ADHD, ODD, or anxiety). You will maketwo visits to CHOP and completeeasy activities related to movement and communication. Allparticipants will complete IQ and diagnostic testing. Parentswill be asked to complete questionnaires prior to their child’s visit and willcomplete interviews at the visit. Compensation and travel reimbursement will be provided.

MEG Autism Study

The Lurie Family Foundations MEG Imaging Lab at CHOP are looking for Healthy Children and those with an Autism Spectrum Disorder for a study on how the brain works. We are looking for both male and female children between the ages of 6-12 years old. We will provide you with reimbursement for your time and parking will be at no cost. For more information please contact our study coordinator by emailing MEGstudies@email.chop.edu.

Brain Imaging Study of Minimally-Verbal/Nonverbal Children with Autism Spectrum Disorder and Children with Developmental/Intellectual Disability

The Lurie Family Foundations MEG Imaging Lab at CHOP are looking for minimally/nonverbal children with ASD and those with an intellectual or developmental delay without ASD who may or may not be minimally/nonverbal for a study on how the brain works. We are looking for both male and female children between the ages of 8-12 years old and infants 4 to 18 months of age. The study involves two visits to CHOP. The first visit can last up to 2 to 5 hours (depending on Cohort group) and will involve neuropsychological/developmental testing. The second visit can last up to 2-3 hours depending on Cohort group and will consist of an MEG brain imaging scan. We will provide you with reimbursement for your time and parking. For more information please contact our study coordinator at 267-426-4914 or megstudies@email.chop.edu.
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