Wyss/Campbell Center for Thoracic Insufficiency Syndrome
The Wyss/Campbell Center for Thoracic Insufficiency Syndrome (CTIS) at Children’s Hospital of Philadelphia (CHOP) is the first program in the nation devoted solely to treating children, teens and young adults with thoracic insufficiency syndrome (TIS), a complex spine and chest wall condition that affects normal breathing and lung growth.
Patients who choose our center have access to complete, multidisciplinary care. We evaluate hundreds of children and teens from around the world. Our center is the only center of its kind that uses a multidisciplinary approach to care by consulting with pulmonologists, general surgeons, cardiologists, neurosurgeons and other specialists, as needed.
Gavin’s Story: Spine Surgery to Correct a Deformity Caused By a Rare Genetic Neuromuscular Disorder

When Gavin was born, doctors didn’t expect him to survive, but thanks to a large team of specialists and a coordinated spine surgery, he’s defying the odds.
Why Choose Us?
Patients and families treated through our multidisciplinary Wyss/Campbell Center for Thoracic Insufficiency Syndrome have access to a team of pioneering surgeons and knowledgeable, caring support staff who can provide a variety of treatment options to children, teens and adults with thoracic insufficiency syndrome. This program involves a unique collaboration between two top-ranked pediatric programs at CHOP: the Division of Orthopaedics and the Division of Pulmonary and Sleep Medicine. Both programs were recognized in U.S. News & World Report’s Honor Roll of Best Children’s Hospitals for 2023-24.
Our Team
Our team includes clinical and research experts from orthopaedics, pulmonology, radiology, genetics and more. Together, the team develops an individual treatment plan for your child.