Congenital Hyperinsulinism Resources for Professionals

Refer a patient

Refer a Patient With Congenital Hyperinsulinism (HI). Learn how and when to refer, and what happens after your patient is referred to CHOP. 

Guide for Referring Physicians (PDF). Learn why to choose CHOP, how to refer patients and what happens next.

Guide for Insurers (PDF). Learn why to choose CHOP, how to refer patients and what happens next.

Congenital Hyperinsulinism Care Profile (PDF). There are four distinct care profiles for children who are diagnosed with or being evaluated for HI.

Preadmission Checklist (PDF). This form should be completed before you patient is admitted at The Children's Hospital of Philadelphia. 

Diagnosis and treatment information

Management of the Patient with Suspected Hyperinsulinism: Recommendations from the Congenital Hyperinsulinism team at CHOP.

Video: Hyperinsulinism Diagnosis, Treatment, Outcomes and Research: Meet our HI experts and learn about our approach to surgical and non-surgical treatment for the disease. 

Criteria for Diagnosing Hyperinsulinism: Review the clinical clues, lab findings, and glycemic response that indicate a diagnosis of HI.

Algorithm for the Treatment of Hyperinsulinism: Assessing the response to diazoxide is a critical step in the management of HI.


Outcomes Data. Learn about outcomes for patients with focal and diffuse congenital hyperinsulinism treated at CHOP.


Scholarly Articles: Our HI experts have published extensively on this rare disease. Review this selection of their work.


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Your Child's HI Appointment

Your first visit will be either an outpatient or inpatient visit, depending on your child’s needs.