Core Lab - Chemistry Laboratory

Our dedicated technologists possess a unique pediatric laboratory testing expertise in each area of the lab, with an average of more than 25 years of experience at The Children's Hospital of Philadelphia.

The Core Lab Chemistry Laboratory performs a wide variety of tests on a stat and routine basis including:

  • Blood Gas analysis and other acute care tests such as Glucose, Lactate, Osmolarity, Co-oximetry and confirmatory Glucose
  • General Chemistry: Electrolytes, Enzymes, Proteins, Lipids, Therapeutic Drug Monitoring (TDM), Toxicology Screens, Endocrinology tests, Sweat test and some panels listed under panels below.
  • The Core Lab Chemistry Lab is open 24 hours daily 7 days a week.
  • The Therapeutic Drugs and Toxicology Screens are offered on a stat and routine basis.
  • Vitamin D25OH testing using the gold standard method of LC/MS/MS
  • Lead testing using ICP/MS method

Blood gas specimens

Blood Gas specimens require a full name of the collector, sealed cap air tight in a heparinized syringe with no bubbles. Proper mixing at the time of collection is essential to prevent clot formation.

Specimens transported via the pneumatic tube system should be double bagged. Blood gas specimens delivered by courier should be on ice and bagged. The requisition form accompanying a blood gas specimen must have the date and time of collection and the collector's full signature. Attach Epic label to second copy of blood gas slip.

For ionized Calcium test, a full 0.7 mL of whole blood in a 1 mL heparinized syringe or 2 mL in a 3 mL syringe is required.

Criteria for specimen rejection or not analyzed (Blood Gas Laboratory)

  • Clotted specimen
  • QNS (quantity not sufficient)
  • Air in syringe
  • Delay in delivery: Stated drawn time to received time greater than 30 min.
  • Specimen transported improperly, e.g. not on ice for Arterial Blood Gas

Criteria for specimen rejection or not analyzed (General)

  • Unlabeled Specimen; with or without a Requisition
  • Mismatch of information on specimen with requisition
  • Received in leaking, cracked or broken container
  • Collected in wrong tube type
  • Exposure to light: applies to specific tests only


Main Building, 5th Floor, Room 5141


24 hours/day, 7 days/week

Shipping address

Clinical Chemistry Lab

The Children’s Hospital of Philadelphia

Main Building, 5th Floor

Room 5141

3401 Civic Center Boulevard

Philadelphia, PA 19104

Forms and reference sheets

Next Steps