Late-onset sepsis is a significant cause of morbidity and mortality among very preterm infants.

CHOP has a core team that performs immediate stabilization and resuscitation of high-risk infants during the time immediately after birth.

Since infants rely on antibodies passed from mother to baby during pregnancy, the findings suggest a need for alternative strategies for boosting infant immunity in the event of an outbreak.

CHOP researchers have led an international group of experts in developing new guidelines for neonatal resuscitation research.

CHOP researchers have found that before the wide availability of vaccines, newborns were infected with SARS-CoV-2 at variable rates and without apparent short-term effects.

CHOP researchers have found nearly one-third of very premature infants develop late-onset sepsis and that 1 in 2 infants born at 23 weeks or earlier either died and/or developed the infection.

Study also suggests vaccine timing is important in maximizing concentration of antibodies transferred to the baby.

The American Academy of Pediatrics now supports giving babies breast milk for the first two years of life; health care professionals at CHOP share these goals for infant feedings.

CHOP researchers found neighborhood characteristics were associated with higher rates of SARS-CoV-2 in pregnancy during the prevaccination era of the COVID-19 pandemic.

Physician-scientist Krithika Lingappan, MD, PhD, MS, recently joined the Division of Neonatology at Children’s Hospital of Philadelphia, and as Associate Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.