Division of Neonatology News

Neonatal resuscitation is a high acuity, low occurrence event. Limited high-quality evidence informs neonatal resuscitation treatment recommendations.

In the midst of a busy day providing hands-on clinical care and developmental evaluations to vulnerable babies and children in our Neonatal Follow-up Program (NFP), there is another less visible but vital activity: research.

In this article, we review a case of a preterm infant with severe bronchopulmonary dysplasia (BPD), a history of S. aureus pneumonia, and subsequent large pneumatocele, managed with a less typical treatment modality.

Late-onset sepsis is a significant cause of morbidity and mortality among very preterm infants.

CHOP has a core team that performs immediate stabilization and resuscitation of high-risk infants during the time immediately after birth.

Since infants rely on antibodies passed from mother to baby during pregnancy, the findings suggest a need for alternative strategies for boosting infant immunity in the event of an outbreak.

CHOP researchers have led an international group of experts in developing new guidelines for neonatal resuscitation research.

CHOP researchers have found that before the wide availability of vaccines, newborns were infected with SARS-CoV-2 at variable rates and without apparent short-term effects.

CHOP researchers have found nearly one-third of very premature infants develop late-onset sepsis and that 1 in 2 infants born at 23 weeks or earlier either died and/or developed the infection.

Study also suggests vaccine timing is important in maximizing concentration of antibodies transferred to the baby.