Born with multiple ventricular septal heart defects, Siena overcame many challenges during her first year. Now 14 months old, she's back home and reaching new milestones.

Born with a backward heart on the wrong side of his chest, Matthew received a heart transplant and is now thriving.

Two-year-old Cooper had overcome open heart surgery, angioplasty and more, but he wasn't talking much and that concerned his parents.

Now 18 months old, Regan is a happy, silly baby who enjoys playing peekaboo, looking in the mirror and snuggling her baby doll.

Hazel is now a high-spirited toddler, a sharp contrast to the early-term baby who was born with Down syndrome and a congenital heart defect.

After cardiac surgery at Children’s Hospital of Philadelphia to repair a defect in his heart, Henry has more energy than ever.

Jude, 2, was born with coarctation of the aorta with aortic arch hypoplasia. Procedures at Children’s Hospital of Philadelphia helped save his life.

Jeremy was born with hypoplastic left heart syndrome (HLHS). After a series of three reconstructive surgeries, he’s now an outgoing 5-year-old.

When Olivia was just 4 days old, she had open-heart surgery to repair her coarctation of the aorta, a congenital heart disease.

Diagnosed with heart defects before birth, Stosh had heart surgery in utero, three reconstructive procedures in his first four years, then a heart transplant.