About the Mitochondrial Medicine
Mitochondrial Medicine at Children’s Hospital of Philadelphia (CHOP) is emerging as the premiere center in the world for multidisciplinary clinical care, advanced diagnostics and therapies, and individualized basic, translational, and clinical research programs dedicated to improving the health of patients of all ages living with mitochondrial disease. Mitochondrial Medicine is designated a Frontier Program by CHOP. Frontier Programs are unique, cutting-edge programs that will forge important new discoveries, deliver novel therapies, and help even more children and adults thrive.
“CHOP has offered us hope toward treatment and even a cure.”
About mitochondrial disease
Mitochondria function as the batteries to produce energy in the body’s cells. Depending on which cells have low-functioning mitochondria, the disease can cause a wide range of health problems, including fatigue, weakness, exercise intolerance, developmental disabilities, seizures, strokes, vision or hearing loss, growth and feeding difficulties, hormone imbalances, and serious problems with heart, liver or kidney function.
Every 30 minutes, a child is born who will develop a mitochondrial disease by age 10. Overall, approximately 1 in every 4,300 individuals in the United States has a mitochondrial disease. Given the various potential presentations that may occur, mitochondrial disease can be difficult to diagnosis and is often misdiagnosed. There are many types of mitochondrial disease, known to result from mutations in nearly 300 different genes. Researchers are still working to identify them and to develop tests for diagnosis and methods for treatment or management.
How CHOP helps
Mitochondrial Medicine focuses on finding the underlying cause of your or your child’s condition. This information helps us determine the best course of treatment for each patient while working in collaboration with your primary care physician, neurologist, and other specialists.
Mitochondrial Medicine is located on the 2nd floor of the Richard D. Wood Pediatric Ambulatory Care Center (Wood Center) at CHOP's Main Campus.
Learn more about scheduling an appointment and what to expect during your first visit.
“There is such coordination of care at CHOP, and such interest in mitochondrial disease. We’re big supporters of the research they are doing. And we feel very lucky to have them. I can’t say enough about what they have done for us.”