In a recent study, researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated that children treated for brain tumors face persistent social challenges, including limited friendships and reduced peer acceptance, extending into adulthood. The study is the first to link disruptions in white matter connectivity to impaired social functioning in survivors of pediatric brain tumors.

Two recent papers from CHOP cancer researchers have advanced the understanding of treatment-resistant pediatric central nervous system tumors.

Through collaboration with research partners, patients, foundations, and community members, we are working to defeat childhood brain cancer and find better treatments for current patients. Read about recent milestones we’ve hit to accelerate pediatric brain tumor research.

CHOP researchers have identified a protein on the surface of multiple pediatric brain tumors that they can target using immunotherapy in preclinical models.

CHOP researchers will use optical coherence tomography (OCT) to measure vision changes associated with NF1-related optic pathway gliomas.

 New therapy shrinks tumors associated with NF1 and improves quality of life.

Children’s Hospital of Philadelphia’s sixth annual Cheers for CHOP raised $735,000 to support pediatric brain tumor research and care.

Learn about CHOP's goal to develop improved, less toxic therapies for pediatric brain tumors by integrating neuro-oncology, neurosurgery, research and big data.

Proton therapy at CHOP helped Elena regain her vision and remain free of craniopharyngioma two years after treatment.

The Healthcare Hero in the field of Cancer was awarded to Phillip “Jay” Storm, MD, for his transformative work in pediatric brain tumor research and care.