Danielle Barber, MD, PhD

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Danielle Barber, MD, PhD, is an attending physician in the Division of Neuorology at Children's Hospital of Philadelphia.

Areas of Expertise: Perinatal brain injury, Hypoxic ischemic encephalopathy, Brain injury after cardiac arrest, Developmental delays
Locations: Main Campus; Buerger Center for Advanced Pediatric Care

Education and Training

Medical School

MD - Yale University School of Medicine, New Haven, CT


General Pediatrics - The Children’s Hospital of Philadelphia, Philadelphia, PA

Neurology and Child Neurology - The Children’s Hospital of Philadelphia, Philadelphia, PA


Research Fellow - The Children’s Hospital of Philadelphia, Philadelphia, PA

Graduate Degree

PhD - Yale University, New Haven, CT

Titles and Academic Titles

Attending Physician

Departments and Services




Cruz FC, Koya E, Guez-Barber DH, Bossert JM, Lupica CR, Shaham Y, Hope BT. New technologies for examining the role of neuronal ensembles in drug addiction and fear. Nature Reviews Neuroscience 2013 Nov; 14(11):743-54. PMID: 24088811


Fanous S, Guez-Barber DH, Goldart EM, Schrama R, Theberge FR, Shaham Y, Hope BT. Unique gene alterations are induced in FACS-purified Fos-positive neurons activated during cue-induced relapse to heroin-seeking. Journal of Neurochemistry 2013 Jan; 124(1):100-8. PMID 23113797


Guez-Barber D, Fanous S, Harvey BK, Zhang Y, Becker KG, Picciotto MR, Hope BT. FACS purification of immunolabeled cell types from adult rat brain. Journal of Neuroscience Methods 2012 Jan 15; 203(1):10-8. PMID: 21911005


Guez-Barber D, Fanous S, Golden SA, Schrama R, Koya E, Stern AL, Bossert JM, Harvey BK, Picciotto MR, Hope BT. FACS identifies unique cocaine-induced gene regulation in selectively activated adult striatal neurons. Journal of Neuroscience 2011 Mar 16; 31(11):4251-9. PMID: 21411666


Koya E, Golden SA, Harvey BK, Guez-Barber DH, Berkow A, Simmons DE, Bossert JM, Nair SG, Uejima JL, Marin MT, Mitchell TB, Farquhar D, Ghosh SC, Mattson BJ, Hope BT. Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization. Nature Neuroscience 2009 Aug;12(8):1069-1073. PMID: 19620976


Abelson JF, Kwan KY, O’Roak BJ, Baek DY, Stillman AA, Morgan TM, Matthews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS 4th, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW. Sequence variants in SLITRK1 are associated with Tourette’s syndrome. Science. 2005 Oct 14;310(5746):317-20. PMID: 16224024

Pooler AM, Guez DH, Benedictus R, Wurtman RJ. Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12. Neuroscience. 2005;134(1):207-14. PMID: 15939540



Junior editor for USMLE Step 1 Review Book: Le T, Krause K, Senior Editors. First Aid Basic Sciences – General Principles. New York: McGraw-Hill, December 2008.

Junior editor for USMLE Step 1 Review Book: Le T, Krause K, Senior Editors. First Aid Basic Sciences – Organ Systems. New York: McGraw-Hill, December 2008.

Posters and Presentations

Invited Lectures


Guez-Barber DH, Sex Differences of Perinatal Brain Injury, Children’s Hospital of Philadelphia Child Neurology Grand Rounds, June 6, 2019.

Guez-Barber DH, McGuire J, The Natural History of Lyme Related Facial Palsy and the Effects of Steroid Use in Children, University of Pennsylvania Neurology Grand Rounds, May 22, 2019.


Guez-Barber DH, Harding B, Multidisciplinary Morbidity and Mortality Conference, Children’s Hospital of Philadelphia Child Neurology Grand Rounds, December 7, 2017.

Awards and Honors

2012, cum laude, Yale University School of Medicine

2012, MD-PhD Alumni Award, Yale University School of Medicine

2010, Fellows Award for Research Excellence, National Institutes of Health

2009-2011, Ruth Kirschstein Individual National Research Service Award for Predoctoral MD-PhD Fellows (F30 DA 024931), PI Danielle Barber

2009, Best Poster Award in Systems Neuroscience, Winter Conference on Brain Research

2008, NIMH travel award, American College of Neuropsychopharmacology (ACNP) Annual Meeting

2003, Award for Excellence in Research in Neuroscience, MIT

2002, MIT International Science and Technology Initiatives Internship, which allowed me to travel to Trieste, Italy and work in the Laboratory for Interdisciplinary Lithography at ELETTRA

2002, First Prize, The S. Klein Prize for Scientific and Technical Writing

2002, Excellent Academic Record Award, Brain and Cognitive Sciences Department, MIT

Leadership and Memberships

Memberships in Professional Organizations

2015-present, American Academy of Neurology
2014-present, American Academy for Cerebral Palsy and Developmental Medicine
2012-present, American Academy of Pediatrics
2009-present, American Physician Scientists Association