Jefferson N. Brownell, MD

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Jefferson N. Brownell, MD, MS, is the Co-Director of the Pancreatic Disorders Program and an attending physician with the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia.

Areas of Expertise: Pediatric gastroenterology, Pancreatic disease, Lymphatic disorders
Locations: Buerger Center for Advanced Pediatric Care; Main Hospital

Education and Training

Medical School

MD - Medical University of South Carolina, Charleston, SC


Pediatrics - Medical University of South Carolina Children's Hospital, Charleston, SC


Pediatrics - Medical University of South Carolina Children's Hospital, Charleston, SC (Chief Resident)


Clinical Pharmacology - Thomas Jefferson University/Children’s Hospital of Philadelphia, Philadelphia, PA
Pediatric Gastroenterology - Children's Hospital of Philadelphia, Philadelphia, PA (Chief Fellow)
Pediatric Nutrition - Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatric Gastroenterology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Attending Physician

Co-Director, Pancreatic Disorders Program

Assistant Professor of Clinical Pediatrics (Gastroenterology, Hepatology and Nutrition), Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services




Gartenberg AJ, Krishnamurthy G, Srinivasan A, Escobar FA, Brownell JN, Mamula P, O'Byrne ML, Dori Y, Smith CL: Intrahepatic and periduodenal embolization for protein-losing enteropathy patients with congenital heart disease. J. Am. Coll. Cardiol 81(25): 2476-2478, Jun 2023.

Ford JL, Green MH, Brownell JN, Green JB, Oxley A, Lietz G, Schall JI, Stallings VA: Use of compartmental modeling and retinol isotope dilution to determine vitamin A stores in young people with sickle cell disease before and after vitamin A supplementation. J Nutr 153(9): 2762-2771, July 2023.


Reeves PT, Bennett WC, McCown MY, Welsh SK, McDonald CM, Beker L, Robbins S, Vitale DS, Siracusa C, Brownell JN, Sellers ZM, Echelmeyer S, Livezey J, Barnes DM: The cystic fibrosis action plan: a low health literacy, pictographic self-management tool with clinical automation. Pediatr Pulmonol 57(11): 2847-2850, July 2022.

Sainath NN, Bales C, Brownell JN, Pickett-Blakely O, Sattar A, Stallings VA. : Impact of Pancreatic Enzymes on Enteral Fat and Nitrogen Absorption in Short Bowel Syndrome. J Pediatr Gastr Nutr 75(1): 36-41, July 2022.


Smith CL, Liu M, Saravanan M, Dewitt A, Biko DM, Pinto E, Escobar F, Krishnamurthy G, Brownell JN, Mamula P, Glatz G, Gillespie M, O'Byrne M, Ravishankar C, Rome J, Dori Y: Liver lymphatic anatomy and role in systematic lymphatic disease. Eur J Radiol 32(1): 112-121, June 2021.

Brownell JN, Biko DM, Mamula P, Krishnamurthy G, Escobar F, Srinivasan A, Laje P, Piccoli DA, Pinto E, Smith CL, Dori Y: Dynamic contrast magnetic resonance lymphangiography localizes protein leak to the duodenum in protein-losing enteropathy. J Pediatr Gastr Nutr 74(1): 38-45, Aug 2021.


Brownell JN, Schall JI, Mcanlis CR, Smith-Whitley K, Norris C, Stallings VA: High-dose vitamin A supplementation in children with sickle cell disease: a randomized, double-blind, dose-finding pilot study. J Pediatr Hematol Oncol 42(2): 83-91, March 2020.

Bashaw H, Brownell JN, Schall JI, Stallings VA: Measures of dietary fat and energy absorption in healthy adults. Pancreas 49(6): 845-854, July 2020.

Brownell JN, Haupt M, Orlova K, Schall JI, Stallings VA: Genetic variants, fat malabsorption, and ancestral background in a small chronic pancreatitis cohort. Pancreas 49(8): e76-e78, September 2020.

Stevens JP, Brownell JN, Freeman J, Bashaw H: COVID-19-associated multisystem inflammatory syndrome in children presenting as acute pancreatitis. J Pediatr Gastr Nutr 71(5): 669-671, November 2020.


Brownell JN, Schall JI, Stallings VA: Pancreatic function in chronic pancreatitis: a cohort study comparing three methods detecting fat malabsorption and the impact of short-term pancreatic enzyme replacement therapy. Pancreas 48(8): 1068-1075, September 2019.




Brownell JN, Padula L, Reid E, Stallings VA, Maqbool A: Pancreatic exocrine insufficiency and pancreatic enzyme replacement therapy in cystic fibrosis: A protocol for clinical practice. Clinical Pancreatology for Practising Gastroenterologists and Surgeons. Juan Enrique Dominguez-Munoz (eds.). Wiley, May 2021.


Brownell JN, Piccoli DA: Protein-Losing Enteropathy. Pediatric Gastrointestinal and Liver Disease, 6th Edition. Wyllie R, Hyams J, Kay M (eds.). Elseiver, October 2020.


Brownell J, Piccoli D. Protein Losing Enteropathy. In: Pediatric Gastrointestinal and Liver Disease, 6th Ed. Elsevier, 2019

Brownell J, McKnight-Menci H, Thornton P, Maqbool A. Pancreatic Insufficiency and Complications of Surgery. In: De Léon-Crutchlow D, Stanley C, editors. Congenital Pediatric Hyperinsulinism. Springer, 2019

Brownell J. Pancreatic Disorders. In: Dean T, St. Geme J, editors. Nelson’s Pediatric Board Review. 1st ed. Elsevier, 2019


Prout E, Shaikhkhalil A, Sainath N, Mitchell J, Brownell J, Stallings V. Feeding Healthy Infants, Children, and Adolescents. In: Nelson’s Textbook of Pediatrics, 21st Ed. Elsevier, 2018

Posters and Presentations

Invited Lectures


Brownell J. "GI Conundrums in Adolescents." Advances in Adolescent Health in Primary Care, Leadership Education in Adolescent Health. Philadelphia, PA. May 2023.

Brownell J. "Long-term Management of Acute Recurrent and Chronic Pancreatitis in Pediatrics." Grand Rounds, New York-Presbyterian/Weill Cornell Medicine Komansky Children's Hospital. New York, NY. Mar 2023.

Brownell J. "Pediatric Pancreatitis: Management in the Modern Era." Grand Rounds, Donald and Barbara Zuscker School of Medicine at Hofstra/Northwell, Cohen Children's Medical Center. Lake Success, NY. Jan 2023.


Brownell J. "Reflux Redux: A Review of Primary Care Management of GERD." Primary Care Perspectives Podcast. Philadelphia, PA. Oct 2022.

Brownell J. "Confusion and Controversies in Pediatric Gastroenterology." Resident Noon Conference (Visiting Professorship), St. Peter's University Hospital. New Brunswick, NJ. Sept 2022.

Brownell J. "Acute, Recurrent, and Chronic Pancreatitis: Diagnosis, Dilemmas, and Management." Grand Rounds (Visiting Professorship), St. Peter's University Hospital. New Brunswick, NJ. Sept 2022.

Brownell J. "An Unusual Case of Acute Recurrent Pancreatitis." PancreasFest 2022. Pittsburgh, PA. July 2022.


Brownell J. "Management of Acute Pancreatitis in Children." University of Miami Miller School of Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition. Miami, FL. Aug 2021.

Brownell J. "Beyond Skimmed Milk: implementation and monitoring nutrition therapy in lymphatic disorders." ASPEN Nutrition Science & Practice Conference, Denver, CO. Mar 2021.

Brownell J. "Acute and Chronic Pancreatitis in Children," University of Miami Pediatric GI Clinic Conference, Miami, FL. Feb 2021.

Awards and Honors

2023, Castle Connolly Top Doctor
2023, Castle Connolly Top LGBTQ Doctor
2020-2021, 2023, GI Fellowship Faculty Teaching Award, Children's Hospital of Philadelphia
2019, Poster of Distinction, Digestive Disease Week, San Diego California
2017, 2018 - Travel Scholarship, Collaborative Alliance for Pancreatic Education and Research, PancreasFest
2017, 2018 - Travel Scholarship, National Pancreas Foundation Fellows’ Symposium
2011-present, Arnold P. Gold Humanism Honor Society

Editorial and Academic Positions

Editorial Positions

2019-present, Ad hoc Reviewer, Pediatric Research

Leadership and Memberships

Memberships in Professional Organizations


2013-present, North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN)
 - 2020-present
2019-present, European Pancreatic Club


2019-present, American Gastroenterological Association
2019-present, European Pancreas Club
2017-present, Collaborative Alliance for Pancreatic Education and Research
2010-present, American Academy of Pediatrics
 - 2017-present, Section on Clinical Pharmacology
 - 2013-present, Section on Lesbian, Gay, Bisexual, and Transgender Health and Wellness