Antonella Cianferoni, MD, PhD

Antonella Cianferoni, MD, PhD
Antonella Cianferoni, MD, PhD, is an attending physician in the Allergy Section at Children's Hospital of Philadelphia.

Areas of Expertise: Asthma, Atopic dermatitis, Allergic rhinitis, IgE mediated food allergy, Eosinophilic esophagitis, Hives, Food protein induced enterocolitis syndrome, Food intolerances, Drug allergy, Mast cell diseases, Other skin disorders, Venom allergy
Locations: Buerger Center for Advanced Pediatric Care; Specialty Care & Surgery Center, King of Prussia

Education and Training

Medical School

MD - University of Florence, Florence, Italy


Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA


Allergy and Immunology - Boston Children's Hospital and Brigham and Women Hospital, Boston, MA

Board Certification


Graduate Degree

PhD in Pediatric Immunology - University of Florence, Florence, Italy

Titles and Academic Titles

Attending Physician

Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services



Poliak N, Elias M, Cianferoni A, Treat J. Acute generalized exanthematous pustulosis: the first pediatric case caused by a contrast agent. Ann Allergy Asthma Immunol. 2010 Sep;105(3):242-3. No abstract available.

Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, Gober L, Kim C, Glessner J, Frackelton E, Thomas K, Blanchard C, Liacouras C, Verma R, Aceves S, Collins MH, Brown-Whitehorn T, Putnam PE, Franciosi JP, Chiavacci RM, Grant SF, Abonia JP, Sleiman PM, Hakonarson H. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet. 2010 Apr;42(4):289-91. Epub 2010 Mar 7. Read abstract.

Cianferoni A, Spergel JM. Food allergy: review, classification and diagnosis. Allergol Int. 2009 Dec;58(4):457-66. Epub 2009 Oct 25. Review. Read abstract.

Cianferoni A, Schneider L, Schantz PM, Brown D, Fox LM. Visceral larva migrans associated with earthworm ingestion: clinical evolution in an adolescent patient. Pediatrics. 2006 Feb;117(2):e336-9. Read abstract.


Cianferoni A., Schroeder J.T., Vierucci A., Lichtenstein L.M., Georas S.N., Casolaro V. Differential Effects of Salicylates on IL-4 and IL-2 Expression in Human CD4+ T Lymphocytes. J Allergy Clin Immunol 1999;103 (2):922

Schroeder J.T., Cianferoni A., Lichtenstein L.M., Casolaro V. Enhanced secretion of IL-4 by human basophils following pre-treatment with Sodium Salicylate and Aspirin. J Allergy Clin Immunol 1999;103 (2):737

Valapour M., Cianferoni A., Cumberland J., Burke T., Seto E., Casolaro V., Georas S. Histone deacetylation inhibits Interlukin-4 (IL-4) gene expression. Am J Resp Crit Care Med, 1999;159

Cianferoni A., Schroeder JT, Clancy Keen J., Schmidt J.W., Georas S.N., Casolaro V. Dissociation of the effects of salicylates on IL-4 gene expression and NFAT activation in human T cell. J Allergy Clin Immunol 2000; 105 (p2):485

Florio G., Cianferoni A.,  Clancy Keen J., Schmidt J.W., Lakenan WA, Georas S.N., Casolaro V. NF-kB-dependent transcription of the IL-13 gene in activated T cells J Allergy Clin Immunol 2000;105 (p2):817

Novembre E., Cianferoni A., Lombardi E., Bernardini R., Favilli T., Pucci N., Brizzi I., Vierucci A. Significance of skin prick test reactivity and total serum IgE level in a group of children with atopic dermatitis seen at age 2 and at age 11. ERS

Keen J.C., Natarajan S. , Burke T., Guo J., Cianferoni A., Schmidt J., Casolaro V. Distinct signal requirements for IL-4 and IL-13 expression. cells J Allergy Clin Immunol J Allergy Clin Immunol 2001:107:489

Schroeder J.T., Miura K., Cianferoni A., Kim H.H., Roche E.M., Sin A.Z., Casolaro V. Nuclear Factor of Activated T Cell (NFAT) Expression in Human Basophils: Evidence for NFAT2 Involvement in IgE-mediated IL-4 Generation. J Allergy Clin Immunol 2001:107:1006

Cianferoni A., Novembre E., Lombardi E., Bernardini R., Mugnaini L., Pucci N., Vierucci A. Clinical features of severe acute anaphylaxis in patients admitted to an University Hospital: an 11 year retrospective review (1985-1996) J Allergy Clin Immunol 2001:107:197

Cianferoni A, Novembre E, Pucci N, Lombardi E, Bernardini R, Vierucci A. Clinical features of anaphylaxis in children: 7 years follow up of 46 cases. J Allergy Clin Immunol 2003:111:127

Cianferoni A, Ramesh N, Gallego MD, Geha RS. Wiskott-Aldrich protein (WASP) is important for NAFT and AP1 activation. J Allergy Clin Immunol 2004

Cianferoni A, Scott J, Bonilla FA, Dioun A, Gellis S, Geha R, Schneider L. Bilateral lower leg swelling and lymphocytic panniculitis in a patient with XLA. J Clinical Immunology  2005


E. November, Cianferoni A. Anaphylaxis (trans: Anaphylaxis). Chapter 20: "Pediatric Emergencies" (trans: Pediatric Critical Care) A. Sarti-P. Busoni Editor, and Pacini. Ospaedaletto (Pi), 1997: pp299-304

Nov. E., A. Cianferoni, Vierucci A. Specific immunotherapy in the treatment of respiratory allergies (trans: Specific immunotherapy for respiratory diseases treatment) 1998 Pisa:Chapter 3;pp353-358

Cianferoni A, Vierucci A cough in children (trans. Cough in children) Chapter 13 in  Allergy Pediatrica- A. Vierucci Medical and Selecta. 2003

Vierucci A, Cianferoni A: Cough in children (trans: Cough in children) and Gentili 2005, Pisa, Italy

Novembre E, Cianferoni A: Uricaria In children in press.