Alexander S. Fairman, MD

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Alexander S. Fairman, MD, is the Director of Pediatric Vascular Surgery at Children's Hospital of Philadelphia.  

Areas of Expertise: Renal artery stenosis and hypertension, Arterial and venous aneurysms, Aortic coarctations, midaortic syndrome, Thoracic Outlet Syndrome (venous, arterial, neurogenic), Popliteal Entrapment Syndrome, Adventitial cystic disease of the popliteal artery, Arteriovenous malformation (AVM), Vascular reconstruction in the setting of oncologic surgery, Vascular trauma, Dialysis access
Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Pereleman School of Medicine, University of Pennsylvania, Philadelphia, PA

Residency

Integrated Vascular Surgery - Hospital of the University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Director, Pediatric Vascular Surgery

Assistant Professor of Surgery, Division of Vascular Surgery and Endovascular Therapy, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Clinical risk prediction of adverse outcomes in patients undergoing vascular surgery

Publications

Papers

2020

Alexander S. Fairman, MD, Grace J. Wang, MD. Spinal Cord Ischemia Management: Current Indications and Timing for Drainage. Endovascular Today. 2020 November.

Fairman AS, Wang GJ. Endovascular Treatment of Ruptured Abdominal Aortic Aneurysms. Semin Intervent Radiol. 2020 Oct;37(4):382-388.

Fairman AS, Fairman RM, Foley PJ, Etkin Y, Jackson OA, Jackson BM. Is Routine Postoperative Anticoagulation Necessary in All Patients after First Rib Resection for Paget-Schroetter Syndrome? Ann Vasc Surg 2020.

Fairman AS, Chin AL, Jackson BM, Foley PJ, Damrauer SM, Kalapatapu V, et al. The evolution of open abdominal aortic aneurysm repair at a tertiary care center. J Vasc Surg 2020.

2019

Fairman AS, Beck AW, Malas MB, Goodney PP, Osborne NH, Schermerhorn ML, et al. Reinterventions in the modern era of thoracic endovascular aortic repair. J Vasc Surg 2019.

2018

Fairman AS, Wang GJ, Jackson BM, Foley PJ, Damrauer SM, Kalapatapu V, et al. Characterization and outcomes of reinterventions in Food and Drug Administration-approved versus trial endovascular aneurysm repair devices. J Vasc Surg 2018;67:1082-90.

2017

Cohen JE, Goldstone AB, Paulsen MJ, Shudo Y, Steele AN, Edwards BB, et al. An innovative biologic system for photon-powered myocardium in the ischemic heart. Sci Adv 2017;3:e1603078.

2016

Edwards BB, Fairman AS (Co-author), Cohen JE, MacArthur JW, Jr., Goldstone AB, Woo JB, et al. Biochemically engineered stromal cell-derived factor 1-alpha analog increases perfusion in the ischemic hind limb. J Vasc Surg 2016;64:1093-9.

2015

Shudo Y, Cohen JE, MacArthur JW, Goldstone AB, Otsuru S, Trubelja A, et al. A Tissue-Engineered Chondrocyte Cell Sheet Induces Extracellular Matrix Modification to Enhance Ventricular Biomechanics and Attenuate Myocardial Stiffness in Ischemic Cardiomyopathy. Tissue Eng Part A 2015;21:2515-25.

Hiraoka A, Cohen JE, Shudo Y, MacArthur JW, Jr., Howard JL, Fairman AS, et al. Evaluation of late aortic insufficiency with continuous flow left ventricular assist devicedagger. Eur J Cardiothorac Surg 2015;48:400-6.

Shudo Y, Cohen JE, MacArthur JW, Goldstone AB, Hiraoka A, Howard J, et al. Non-resectional leaflet remodeling mitral valve repair preserves leaflet mobility: A quantitative echocardiographic analysis of mitral valve configuration. Int J Cardiol 2015;186:16-8.

2014

Cohen JE, Purcell BP, MacArthur JW, Jr., Mu A, Shudo Y, Patel JB, et al. A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy. Circ Heart Fail 2014;7:619-26.

Trubelja A, MacArthur JW, Sarver JJ, Cohen JE, Hung G, Shudo Y, et al. Bioengineered stromal cell-derived factor-1alpha analogue delivered as an angiogenic therapy significantly restores viscoelastic material properties of infarcted cardiac muscle. J Biomech Eng 2014;136.

Macarthur JW, Jr., Cohen JE, McGarvey JR, Shudo Y, Patel JB, Trubelja A, et al. Preclinical evaluation of the engineered stem cell chemokine stromal cell-derived factor 1alpha analog in a translational ovine myocardial infarction model. Circ Res 2014;114:650-9.

2013

Atluri P, Fairman AS, MacArthur JW, Goldstone AB, Cohen JE, Howard JL, et al. Continuous flow left ventricular assist device implant significantly improves pulmonary hypertension, right ventricular contractility, and tricuspid valve competence. J Card Surg 2013;28:770-5.

MacArthur JW, Jr., Cohen JE, Goldstone AB, Fairman AS, Edwards BB, Hornick MA, et al. Nonresectional single-suture leaflet remodeling for degenerative mitral regurgitation facilitates minimally invasive mitral valve repair. Ann Thorac Surg 2013;96:1603-6.

Atluri P, Trubelja A, Fairman AS, Hsiao P, MacArthur JW, Cohen JE, et al. Normalization of postinfarct biomechanics using a novel tissue-engineered angiogenic construct. Circulation 2013;128:S95-104.

Atluri P, Goldstone AB, Fairman AS, MacArthur JW, Shudo Y, Cohen JE, et al. Predicting right ventricular failure in the modern, continuous flow left ventricular assist device era. Ann Thorac Surg 2013;96:857-63; discussion 63-4.

MacArthur JW, Jr., Purcell BP, Shudo Y, Cohen JE, Fairman AS, Trubelja A, et al. Sustained release of engineered stromal cell-derived factor 1-alpha from injectable hydrogels effectively recruits endothelial progenitor cells and preserves ventricular function after myocardial infarction. Circulation 2013;128:S79-86.

Yasuhiro Shudo, MD, Jeffrey Cohen, MD, John MacArthur, Jr, MD, Pavan Atluri, MD, Philip Hsiao, BS, Elaine Yang, BS, Alexander Fairman, BA, Alen Trubelja, BS, Jay Patel, BS, Shigeru Miyagawa, MD, Yoshiki Sawa, MD, Y. Joseph Woo, MD. Spatially-Oriented, Temporally- Sequential SMC-EPC Bi-Level Cell-Sheet Neovascularizes Ischemic Myocardium. Circulation. Spring 2013.

Kaczorowski DJ, Macarthur JW, Howard J, Kobrin D, Fairman AS, Woo YJ. Quantitative evaluation of change in coexistent mitral regurgitation after aortic valve replacement. J Thorac Cardiovasc Surg 2013;145:341-7; discussion 7-8.

MacArthur JW, Jr., Trubelja A, Shudo Y, Hsiao P, Fairman AS, Yang E, et al. Mathematically engineered stromal cell-derived factor-1alpha stem cell cytokine analog enhances mechanical properties of infarcted myocardium. J Thorac Cardiovasc Surg 2013;145:278-84.

Atluri P, Ullery BW, MacArthur JW, Goldstone AB, Fairman AS, Hiesinger W, et al. Rapid onset of fulminant myocarditis portends a favourable prognosis and the ability to bridge mechanical circulatory support to recovery. Eur J Cardiothorac Surg 2013;43:379-82

Books

Chapters

2019

Fairman A S, Damrauer S M. Genetic Vascular Disorders. In: Valentine J R, Eidt J F, editors. Vascular and Endovascular Surgery [online]. Hamilton ON: Decker Medicine; April 2019. DOI: 10.2310/7800.3081.

Posters and Presentations

Invited Lectures

2021

Fairman AS. “Local Versus General Anesthesia in Patients Undergoing Thoracic Endovascular Aortic Repair”—Poster presentation, Vascular Annual Meeting (Society for Vascular Surgery), San Diego, California. Aug 2021.

2020

Fairman AS. “The Impact of Center Volume on Trends in Contemporary Open Abdominal Aortic Aneurysm Repair”—Poster presentation, Vascular Annual Meeting (Society for Vascular Surgery), Toronto, Canada. June 2020.

2019

Fairman AS. “The Evolution of Open AAA Repair at a Tertiary Care Center”—Podium Presentation, Eastern Vascular Society Annual Meeting, Pittsburgh, Pennsylvania. Sept 2019.

Fairman AS. “Transaxillary 1st Rib Resection for Paget-Schroetter Syndrome: Routine Postoperative Anticoagulation Is Unnecessary”—Podium Presentation, Vascular and Endovascular Surgical Society Annual Meeting, Washington, DC. June 2019.

Fairman AS. “The Evolution of Open AAA Repair at a Tertiary Care Center”—Poster Presentation, Vascular Annual Meeting (Society for Vascular Surgery), Washington, DC. June 2019.

Fairman AS. “Cervical Debranching for Aortic Arch Reconstruction”—Podium Presentation, Delaware Valley Vascular Society Spring Meeting, Philadelphia, PA. May 2019.

Awards and Honors

2019, First place, podium presentation, Delaware Valley Vascular Surgery Society
2018, Second place, interactive poster presentation, Eastern Vascular Society Annual Meeting
2017, First place medical student talk, Introduction to Academic Vascular Surgery
2014, Student Fellowship in Cardiovascular Disease, American Heart Association
2014, D. Hayes Agnew Surgical Society Summer Fellowship, Department of Surgery, Hospital of the University of Pennsylvania
2011-2013, Harrison Surgical Scholar, Hospital of the University of Pennsylvania
2009, Cum Laude, University of Pennsylvania
2007-2009, University of Pennsylvania Men’s Varsity Soccer Team
2007, Dean’s List, Georgetown University
2005-2007, Georgetown University Varsity Men’s Soccer Team

Leadership and Memberships

Memberships in Professional Organizations

2017-present, American College of Surgeons
2017-present, Society for Vascular Surgery