Brian T. Fisher, DO, MPH, MSCE

Brian T. Fisher, DO, MPH, MSCE

Brian Fisher, DO, MPH, MSCE, is Director of the Pediatric Infectious Diseases Fellowship Training Program and a senior scholar within the Penn Center for Clinical Epidemiology and Biostatistics. 

Areas of Expertise: Infections in immunocompromised children
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

DO - Chicago College of Osteopathic Medicine, Chicago, IL

Residency

General Pediatrics - Hope Children's Hospital, Oak Lawn, IL (Chief Resident)

Fellowship

Pediatric Infectious Diseases - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatric Infectious Diseases
Pediatrics

Graduate Degree

MPH in Epidemiology - University of Illinois at Chicago, Chicago, IL
MS in Clinical Epidemiology - University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Attending Physician

Director, Pediatric Infectious Diseases Fellowship Training Program

Associate Professor of Pediatrics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Dr. Fisher's research focuses on infections in children with immunocompromising conditions. He is particularly interested in infections in children with cancer and serves as the Chair of the Infectious Disease Domain within the Children’s Oncology Group.

Publications

Papers

2018

Fisher Brian T, Boge Craig LK, Petersen Hans , Seif Alix E, Bryan Matthew, Hodinka Richard L, Cardenas Ana Maria, Purdy Dale R, Loudon Brandon, Kajon Adriana E.: Outcomes of Human Adenovirus Infection and Disease in a Retrospective Cohort of Pediatric Hematopoietic Cell Transplant Recipients. J Pediatric Infect Dis Soc epub head of print 2018.

Elgarten Caitlin W, Levy Ellen M, Mattei Peter, Fisher Brian T, Olson Tim S, Freedman Jason L: Successful treatment of pulmonary mucormycosis in two pediatric hematopoietic stem cell transplant patients. Pediatr Transplant epub ahead of print 2018.

Downes KJ, Ellis D, Lavigne S, Bryan M, Zaoutis TE, Fisher BT: The use of echinocandins in hospitalized children in the United States. Med Mycol epub ahead of print 2018.

Diorio C, Robinson PD, Ammann RA, Castagnola E, Erickson K, Esbenshade A, Fisher BT, Haeusler GM, Kuczynski S, Lehrnbecher T, Phillips R, Cabral S, Dupuis LL, Sung L: Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients. J Clin Oncol epub  ahead of print 2018.

Danziger-Isakov L, Steinbach WJ, Paulsen G, Munoz FM, Sweet LR, Green M, Michaels MG, Englund JA, Murray A, Halasa N, Dulek DE, Madan RP, Herold BC, Fisher BT: A Multicenter Consortium to Define the Epidemiology and Outcomes of Pediatric Solid Organ Transplant Recipients With Inpatient Respiratory Virus Infection. J Pediatric Infect Dis Soc epub ahead of print 2018.

Citrin R, Getz KD, Li Y, Huang YS, Horowitz JP, Seif AE, Fisher BT, Aplenc R: The epidemiology of rasburicase use in paediatric patients with acute lymphoblastic leukaemia and non-Hodgkin lymphoma. Br J Haematol epub ahead of print 2018.

Savla JJ, Fisher BT, Faerber JA, Huang YV, Mercer-Rosa L: Complete Versus Staged Repair for Neonates With Tetralogy of Fallot: Establishment and Validation of a Cohort of 2235 Patients Using Detailed Surgery Sequence Review of Health Care Administrative Data. Med Care 56(11): e76-e82, Nov 2018.

Alexander S, Fisher BT, Gaur AH, Dvorak CC, Villa Luna D, Dang H, Chen L, Green M, Nieder ML, Fisher B, Bailey LC, Wiernikowski J, Sung L; Children's Oncology Group: Effect of Levofloxacin Prophylaxis on Bacteremia in Children With Acute Leukemia or Undergoing Hematopoietic Stem Cell Transplantation: A Randomized Clinical Trial. JAMA 320(10): 995-1004, Sept 2018.

Elgarten Caitlin W, Arnold Staci D, Li Yimei, Huang YV, Riches ML, Gerber Jeffrey S, Aplenc Richard, Saber Wael, Fisher Brian T: Hospital-Level Variability in Broad-Spectrum Antibiotic Use for Children With Acute Leukemia Undergoing Hematopoietic Cell Transplantation. Infect Control Hosp Epidemiol 33(9): 2821-26, Jul 2018.

Fitzgerald JC, Li Y, Fisher BT, Huang YS, Miller TP, Bagatell R, Seif AE, Aplenc R, Thomas NJ: Hospital Variation in Intensive Care Resource Utilization and Mortality in Newly Diagnosed Pediatric Leukemia. Pediatr Crit Care Med 19(6): e312-e320, June 2018.

Downes KJ, Laskin BL, Fisher BT: The Cost of Vancomycin and Piperacillin/Tazobactam Treatment-Reply. JAMA Pediatr 172(5): 494-95, May 2018.

Getz Kelly D, Miller Tamara P, Seif Alex E, Li Yimei, Huang YV, Fisher Brian T, Aplenc Richard: Opioid utilization among pediatric patients treated for newly diagnosed acute myeloid leukemia. PLoS One 13(2), Feb 2018.

Smith RJ, Klieger SB, Sulieman SE, Berger E, Treat JR, Fisher BT: Retrospective review of immunocompromised children undergoing skin biopsy for suspected invasive infection: Analysis of factors predictive of invasive mold. Pediatr Dermatol 35(1): 104-11, Jan 2018.

DiNofia AM, Seif AE, Devidas M, Li Y, Hall M, Huang YV, Cahen V, Hunger SP, Winick NJ, Carroll WL, Fisher BT, Larsen EC, Aplenc R: Cost comparison by treatment arm and center-level variations in cost and inpatient days on the phase III high-risk B acute lymphoblastic leukemia trial AALL0232. Cancer Med 7(1): 3-12, Jan 2018.

2017

Winestone LE, Getz KD, Miller TP, Li Y, Huang YS, Seif AE, Fisher BT, Aplenc R.: Complications preceding early deaths in Black and White children with acute myeloid leukemia.  Pediatr Blood Cancer. 64(12), Dec 2017.

Winestone LE, Getz KD, Miller TP, Li Y, Huang YS, Seif AE, Fisher BT, Aplenc R: Complications preceding early deaths in Black and White children with acute myeloid leukemia. Pediatr Blood Cancer 64(12), Dec 2017.

Saxena Shikha, Gee Jerica, Klieger Sarah B, Kajon Adriana, Petersen Hans, Zaoutis Theoklis E, Fisher Brian T: Invasive Fungal Disease in Pediatric Solid Organ Transplant Recipients. Journal of the Pediatric Infectious Diseases Society epub ahead of print 2017.

Fisher Brian T, Danziger-Isakov Lara, Sweet Leigh R, Munoz Flor M, Maron Gabriela, Tuomanen Elaine, Murray Alistair, Englund Janet A, Dulek Daniel, Halasa Natasha, Green Michael, Michaels Marian G, Madan Rebecca P, Herold Betsy C, Steinbach William J: A Multicenter Consortium to Define the Epidemiology and Outcomes of Inpatient Respiratory Viral Infections in Pediatric Hematopoietic Stem Cell Transplant Recipients. Journal of the Pediatric Infectious Diseases Society epub  ahead of print 2017.

Citrin R, Horowitz JP, Reilly AF, Li Y, Huang YS, Getz KD, Seif AE, Fisher BT, Aplenc R.: Creation of a pediatric mature B-cell non-Hodgkin lymphoma cohort within the Pediatric Health Information System Database. PLoS One. Epub ahead of print, 23 Oct 2017.

Downes KJ, Cowden C, Laskin BL, Huang YS, Gong W, Bryan M, Fisher BT,  Goldstein SL, Zaoutis TE.: Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children. JAMA Pediatr. Epub ahead of print, Oct 2 2017.

Steinbach WJ, Fisher BT.: International Collaborative on Contemporary Epidemiology and Diagnosis of Invasive Fungal Disease in Children. J Pediatric Infect Dis Soc.  Guest Editor. (eds.). 6(1): S1-S2, Sept 1 2017.

Miller Tamara P, Li Yimei, Kavcic Marco, Getz Kelly D, Huang Yuan-shung, Sung Lillian, Alonzo Todd A, Gerbing Robert Daves MH, Horton TM, Pulsipher Michael A, Pollard Jess, Bagatell Rochelle, Seif Alix E, Fisher Brian T, Luger S, Gamis Alan S, Adamson Peter C, Aplenc Richard: Center-level variation in accuracy of adverse event reporting in a clinical trial for pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Haematologica 102(9): e340-e343, September 2017.

Katragkou A, Fisher BT, Groll AH, Roilides E, Walsh TJ.: Diagnostic Imaging and Invasive Fungal Diseases in Children. J Pediatric Infect Dis Soc. 6(1): S12-321, Sept 1 2017 Notes: Guest Editor.

Huppler AR, Fisher BT, Lehrnbecher T, Walsh TJ, Steinbach WJ.: Role of Molecular Biomarkers in the Diagnosis of Invasive Fungal Diseases in Children. J Pediatric Infect Dis Soc.  6(1): S32-S44, Sept 1 2017 Notes: Guest Editor.

Fisher Brian T, Robinson Paula D, Lehrnbecher Thomas, Steinbach William J, Zaoutis Theoklis E, Phillips Bob, Sung Lillian: Risk Factors for Invasive Fungal Disease in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review. Journal of the Pediatric Infectious Diseases Society Epub ahead of print: doi: 10.1093, May 26 2017.

Miller Tamara P, Li Yimei, Getz Kelly D, Dudley J, Burrows E, Pennington J, Ibrahimova A, Fisher Brian T, Bagatell Rochelle, Seif Alix E, Grundmeier Robert, Aplenc Richard.: Using electronic medical record data to report laboratory adverse events. British Journal Haematology 177(2): 183-86, April 2017.

Winestone LE, Getz KD, Miller TP, Wilkes JJ, Sack L, Li Y, Huang YS, Seif AE, Bagatell R, Fisher BT, Epstein AJ, Aplenc R.: The role of acuity of illness at presentation in early mortality in black children with acute myeloid leukemia. American Journal of Hematology 92(2): 141-48, February 2017

2016

Fisher Brian T, Vendetti Neika, Bryan Matthew, Prasad Priya A, Localio A. Russell, Damianos Andreas, Coffin Susan E, Bell Louis M, . Walsh Thomas J, Gross Robert, Zaoutis Theoklis E: Central Venous Catheter Retention and Mortality in Children with Candidemia: A Retrospective Cohort Analysis  Journal of the Pediatric Infectious Disease Society  J Pediatric Infect Dis Soc. 2016 Dec;5(4):. (eds.). 5(4): 403-408, Dec 2016 Notes: Epub 2015 Aug 16.

Fisher Brian T, Ross Rachael K, Roilides Emmanuel, Palazzi Debra L, Abzug Mark J, Hoffman Jill A, Berman David B, Prasad Priya A, Localio Russell, Steinbach William J, Vogiatzi Lambrini, Dutta Ankhi, Zaoutis Theoklis E: Failure to Validate a Multivariable Clinical Prediction Model to Identify Pediatric ICU Patients at High-Risk for Candidemia. Journal of the Pediatric Infectious Diseases Society  4: 458-461, Dec 2016 Notes: Epub 2015 Apr 29.

Chiotos K, Vendetti N, Zaoutis TE, Baddley J, Ostrosky-Zeichner L, Pappas P, Fisher BT.: Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis: a retrospective observational cohort study of the Mycoses Study Group (MSG-12). The Journal of Antimicrobial Chemotherapy 71(12): 3536-3539, Dec 2016.

Rao P, Li Y, Getz KD, Miller TP, Huang YS, Wilkes JJ, Seif AE, Bagatell R, Fisher BT, Gracia C,Aplenc R: Low rates of pregnancy screening in adolescents before teratogenic exposures in a national sample of children's hospitals. Cancer 122(21): 3394-3400, Nov 15 2016.

Getz KD, Miller TP, Seif AE, Li Y, Huang YS, Alonzo T, Gerbing R, Sung L, Hall M, Bagatell R, Gamis A, Fisher BT, Aplenc R.: Early discharge as a mediator of greater ICU-level care requirements in patients not enrolled on the AAML0531 clinical trial: a Children's Oncology Group report. Cancer Medicine 5(9): 2412-6, Sept 2016.

Salazar Elizabeth G, Li Yimei, Fisher Brian T, Rheingold Sue R, Fitzgerald Julie, Seif Alix E, Huang Yuan-Shung, Bagatelle Ro, Aplenc Richard: Supportive care utilization and treatment toxicity in children with Down syndrome and acute lymphoid leukaemia at free-standing paediatric hospitals in the United States. Br J Haematology 174(4): 591-9, Aug 2016.

Wilkes  Jennifer, Hennessy Sean, Xiao Rui, Rheingold Susan,  Seif Alix E, Huang Yuan-Shung, Vendetti Neika, Li Yimei, Bagatell Rochelle, Aplenc Richard, Fisher Brian T: Volume - Outcome Relationships in Pediatric Acute Lymphoblastic Leukemia:  Association between Hospital Pediatric and Pediatric Oncology Volume with Mortality and Intensive Care Resources during Initial Therapy. Clinical Lymphoma, Myeloma & Leukemia 16(7): 404-410, July 2016.

Miller Tamara P, Getz Kelly D, Kavcic Marco, Li Yimei, Huang Yuan-Shung, Sung Lillian, Alonzo Todd A, Gerbing Robert, Daves M, Horton TM, Pulsipher Michael A, Pollard Jess, Bagatell Rochelle, Seif Alix E, Fisher Brian T, Gamis Alan S, Aplenc Richard: A comparison of discharge strategies after chemotherapy completion in pediatric patients with acute myeloid leukemia: a report from the Children's Oncology Group. Leuk Lymphoma 57(7): 1567-74, Jul 2016.

Vendetti N, Gerber JS, Sammons JS, Fisher BT, Zaoutis TE, Coffin SE: Administration of Palivizumab in the NICU. Hospital Pediatrics 6(6): 354-8, June 2016.

Hamula Camille L, Hughes Kenneth, Fisher Brian T, Zaoutis Theoklis E, SIngh Ila R, Velegraki Aristea : T2Candida Provides Rapid and Accurate Species Identification in Pediatric Cases of Candidemia. American Journal of Clinical Pathology 145(6): 858-61, June 2016.

Miller Tamara P, Li Yimei, Kavcic Marco, Troxel Andrea B, Huang Yuan-Shung, Sung Lillian, Alonzo Todd A, Gerbing Robert, Hall Matt, Daves MH, Horton TM, Pulsipher Michael A, Pollard Jessica A, Bagatell Rochelle, Seif Alix E, Fisher Brian T, Luger S, Gamis Alan S, Adamson Peter C, Aplenc Richard.: Accuracy of Adverse Event Ascertainment in Clinical Trials for Pediatric Acute Myeloid Leukemia. J Clin Oncol 34(13): 1537-43, May 2016.

Desai Ami V, Seif Alix E, Li Yimei, Getz Kelly, Fisher Brian T, Huang Yuan-Shung, Mante A, Aplenc Richard, Bagatell Rochelle.: Resource Utilization and Toxicities After Carboplatin/Etoposide/Melphalan and Busulfan/Melphalan for Autologous Stem Cell Rescue in High-Risk Neuroblastoma Using a National Administrative Database. Pediatric Blood & Cancer 63(5): 901-7, May 2016.

Heneghan MB, Rheingold Sue R, Li Yimei, Seif Alix E, Huang Yuan-Shung, McLeod Lisa, Wells Lawrence, Fisher Brian T, Aplenc Richard: Treatment of Osteonecrosis in Children and Adolescents With Acute Lymphoblastic Leukemia. Clinical Lymphoma, Myeloma & Leukemia 16(4): 223-29, April 2016.

Vendetti Neika, Bryan Matthew, Zaoutis Theoklis E, Damianos Andreas, Fisher Brian T: Comparative effectiveness of fungicidal vs. fungistatic therapies for the treatment of pediatric candidemia. Mycoses 59(3): 173-8, March 2016.

DiNofia Amanda M, Salazar Elizabeth, Seif Alix E, Li Yimei, Huang Yuan-Shung, Bagatell Rochelle, Fisher Brian T, Aplenc Richard: Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States. PLoS One 11(3): e0151362, March 2016.

De Luca Maia, Green Michael, Symmonds Jen, Klieger Sarah B, Soltys K, Fisher Brian T: Invasive candidiasis in liver transplant patients: Incidence and risk factors in a pediatric cohort. Pediatric Transplantation 20(2): 235-40, March 2016.

2015

Wattier Rachel L, Dvorak Christopher C, Hoffman Jill A, Brozovich Ava A, Bin-Hussain Ibrahim, Groll Andreas H, Castagnola Elio, Knapp Katerine M, Zaoutis Theoklis E, Gustafsson Britt, Sung Lillian, Berman David, Halasa Natasha B, Abzug Mark J, Velegraki Aristea, Sharma Tanvi S, Fisher Brian T, Steinbach William J: A Prospective, International Cohort Study of Invasive Mold Infections in Children. Journal of the Pediatric Infectious Disease Society 4(4): 313-22, Dec 2015.

Lee Grace, Fisher Brian T, Xiao Rui, Coffin Susan, Feemster Kristen, Seif Alix, Yimei Li, Aplenc Richard: Burden of Influenza-Related Hospitalizations and Attributable Mortality in Pediatric Acute Lymphoblastic Leukemia. Journal of the Pediatric Infectious Disease Society 4(4): 290-6, Dec 2015.

Alexander Sarah, Pole Jason D, Gibson Paul, Lee Michelle, Hesser Tanya, Chi Susan, Dvorak Christopher C, Fisher Brian T, Hasle Henrik, Kanerva Jukka, Möricke Anja, Phillips Bob, Raetz Elizabeth, Rodriguez-Galindo Carlos, Samarasinghe Sujith, Schmiegelow Kjeld, Tissing Wim, Lehrnbecher Thomas, Sung Lillian : Classification of treatment-related mortality in children with cancer: a systematic assessment. The Lancet Oncology 16(16): e604-10, Dec 2015.

Li Yimei, Hall Matt, Fisher Brian T, Seif Alix E, Huang Yuan-Shung, Bagatell Rochelle, Getz Kelly D, Alonzo Todd A, Gerbing Robert B, Sung Lillian, Adamson Peter C, Gamis Alan, Aplenc Richard: Merging Children's Oncology Group Data with an External Administrative Database Using Indirect Patient Identifiers: A Report from the Children's Oncology Group. PLoS One 10(11): e0143480, Nov 2015.

Getz Kelly, Li Yimei, Alonzo Todd, Hall Matthew, Gerbing Robert, Sung Lillian, Huang Yuan-Shung, Arnold Staci, Seif Alix, Miller Tamara, Bagatel Rochelle, Fisher Brian T, Adamson Peter, Gamis Alan, Keren Ron, Aplenc Richard: Comparison of In-Patient Costs for Children Treated on the AAML0531 Clinical Trial: A Report from the Children's Oncology Group. Pediatric Blood & Cancer 62(10): 1775-81, October 2015.

Getz Kelly D, Miller Tamara P, Seif Alix E, Li Yimei, Huang Yuan-Shung, Bagatell Rochelle, Fisher Brian T, Aplenc Richard: A comparison of resource utilization following chemotherapy for acute myeloid leukemia in children discharged versus children that remain hospitalized during neutropenia. Cancer Medicine 4(9): 1356-64, September 2015.

Miller Tamara P, Troxel Andrea B, Li Yimei, Huang Yuan-Shung, Alonzo Todd A, Gerbing Robert, Hall Matt, Torp Kari, Fisher Brian T, Bagatell Rochelle, Seif Alix, Sung Lillian, Gamis Alan, Rubin David, Luger Selina, Aplenc Richard: Comparison of administrative/billing data to expected protocol-mandated chemotherapy exposure in children with acute myeloid leukemia: A report from the Children's Oncology Group. Pediatric Blood & Cancer 62(7): 1184-9, July 2015.

Klieger Sarah B, Vendetti Neika D, Fisher Brian T, Gerber Jeff S: Staphylococcus aureus bacteremia in hospitalized children: incidence and outcomes. Infect Control Hosp Epidemiol 36(5): 603-5, May 2015.

Seif Alix E, Walker Dana M, Li Yimei, Huang Yuan-Shung V, Kavcic Marko, Torp Kari, Bagatell Rochelle, Fisher Brian T, Aplenc Richard: Dexrazoxane exposure and risk of secondary acute myeloid leukemia in pediatric cancer patients   Pediatric Blood & Cancer 62(4): 704-09, April 2015.

Patel Roshni R, Hodinka Richard L, Kajon Adriana E, Klieger Sarah, Oikonomopoulou Zacharoula, Peterson Hans, Rand Elizabeth, Attiyeh Edward F, Fisher Brian T: A Case of Adenovirus Viremia in a Pediatric Liver Transplant Recipient with Neutropenia and Lymphopenia: Who and When Should We Treat? Journal of the Pediatric Infectious Disease Society 4(1): e1-5, March 2015.

2014

Goodman EK, Reilly AF, Fisher BT, Fitzgerald J, Li Y, et al. Association of weekend admission with hospital length of stay, time to chemotherapy, and risk for respiratory failure in pediatric patients with newly diagnosed leukemia at freestanding US children's hospitals. JAMA pediatrics. 2014; 168(10):925-31. NIHMSID: NIHMS681278

Freedman JL, Faerber J, Kang TI, Dai D, Fisher BT, et al. Predictors of antiemetic alteration in pediatric acute myeloid leukemia. Pediatric blood & cancer. 2014; 61(10):1798-805. NIHMSID: NIHMS607842

Palazzi DL, Arrieta A, Castagnola E, Halasa N, Hubbard S, et al. Candida speciation, antifungal treatment and adverse events in pediatric invasive candidiasis: results from 441 infections in a prospective, multi-national study. The Pediatric infectious disease journal. 2014; 33(12):1294-6.

Desai AV, Kavcic M, Huang YS, Herbst N, Fisher BT, et al. Establishing a high-risk neuroblastoma cohort using the Pediatric Health Information System Database. Pediatric blood & cancer. 2014; 61(6):1129-31. NIHMSID: NIHMS637631

Maude SL, Fitzgerald JC, Fisher BT, Li Y, Huang YS, et al. Outcome of pediatric acute myeloid leukemia patients receiving intensive care in the United States. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2014; 15(2):112-20. NIHMSID: NIHMS681302

Fisher BT, Kavcic M, Li Y, Seif AE, Bagatell R, et al. Antifungal prophylaxis associated with decreased induction mortality rates and resources utilized in children with new-onset acute myeloid leukemia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2014; 58(4):502-8.

Seif AE, Fisher BT, Li Y, Torp K, Rheam DP, et al. Patient and hospital factors associated with induction mortality in acute lymphoblastic leukemia. Pediatric blood & cancer. 2014; 61(5):846-52. NIHMSID: NIHMS545529

Lee GE, Sung L, Fisher BT, Sullivan KE, McWilliams T, et al. Gene expression profiling to predict viridans group streptococcal and invasive fungal infection in pediatric acute myeloid leukemia: a brief report from the Children's Oncology Group. Acta haematologica. 2014; 131(3):167-9. NIHMSID: NIHMS689342

Fisher BT, Ross RK, Localio AR, Prasad PA, Zaoutis TE. Decreasing rates of invasive candidiasis in pediatric hospitals across the United States. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2014; 58(1):74-7.

Fisher BT, Singh S, Huang YS, Li Y, Gregory J, et al. v Pediatric blood & cancer. 2014; 61(1):68-73. NIHMSID: NIHMS550131

2013

Lothstein Katerine, Fisher Brian T, Li Yimei, Seif Alix E, Kavcic Marko, Huang Yuan-Shung V,  Rheingold Susan R, Aplenc Richard: Zoonotic Infections in Pediatric Patients with Acute Leukemia. Pediatric Blood & Cancer 60(12): e160-2, December 2013.

de Blank Peter, Zaoutis Theoklis, Fisher Brian T, Troxel Andrea, Kim Jason, Aplenc Richard: Trends in Clostridium difficile Infection and Risk Factors for Hospital Acquisition of Clostridium difficile among Children with Cancer. The Journal of Pediatrics 163(3): 699-705, September 2013.

Prasad Priya A, Fisher Brian T, Coffin Susan E, Walsh Thomas J, McGowan Karin L, Gross Robert, Zaoutis Theoklis E. : Pediatric Risk Factors for Candidemia Secondary to Candida glabrata and Candida krusei Species  Journal of the Pediatric Infectious Disease Society 2(3): 263-266, September 2013.

Fisher Brian T, Gerber Jeffrey S, Leckerman Kateri H, Seif Alix E, Huang Yuan-Shung V, Li Yimei, Harris Tracey, Torp Kari, Rheam Douglas, Shah Ami, Walker Dana, Aplenc Richard: Variation in Hospital Antibiotic Prescribing Practices for Children with Acute Lymphoblastic Leukemia  Leukemia & Lymphoma 54(8): 1633-39, August 2013.

Kavcic Marko, Fisher Brian T, Seif Alix E, Li Yimei,  Huang Yuan-Shung, Walker Dana, Aplenc Richard: Leveraging Administrative Data to Monitor Rituximab Use in 2,875 Patients at 42 Free Standing Children's Hospitals Across the United States The Journal of Pediatrics. The Journal of Pediatrics 162(6): 1252-58, June 2013.

Buser Genevieve L, Fisher Brian T, Shea Judy A, Coffin Susan E: Parent Willingness to Remind Healthcare Workers to Perform Hand Hygiene. American Journal of Infection Control 41(6): 492-6, June 2013.

Kavcic Marko, Fisher Brian T, Li Yimei, Seif Alix E, Torp Kari, Walker Dana M, Huang Yuan-Shung, Lee Grace E, Tasian Sarah K, Vujkovic Marijana, Bagatell Rochelle, Aplenc Richard: Induction Mortality and Resource Utilization in Children Treated for Acute Myeloid Leukemia at Free-Standing Pediatric Hospitals in the United States. Cancer 119(10): 1916-1923, May 2013.

Walker Dana M, Fisher Brian T, Seif Alix E, Huang Yuan-Shung V, Torp Kari, Li Yimei, Aplenc Richard: Dexrazoxane Use in Pediatric Patients with Acute Lymphoblastic or Myeloid Leukemia From 1999 to 2009: Analysis of a National Cohort of Patients in the Pediatric Health Information Systems Database. Pediatric Blood & Cancer 60(4): 616-20, April 2013.

Kavcic Marko, Fisher Brian, Torp Kari, Li Yimei, Huang Yuan-Shung, Seif Alix, Vujkovic Marijana,  Aplenc Richard: Assembly of a cohort of children treated for acute myeloid leukemia at free-standing children's hospitals in the United States using an administrative database. Pediatric Blood & Cancer 60(3): 508-511, March 2013.

Fierro Julie L, Prasad Priya A, Fisher Brian T, Gerber Jeffrey S, Coffin Susan E, Walsh Thomas J, Zaoutis Theoklis E: Ocular Manifestations of Candidemia in Children. The Pediatric infectious disease journal 32(1): 84-6, Jan 2013.

2012

Lehrnbecher Thomas, Phillips Robert S, Alexander Sarah, Alvaro Frank, Carlesse Fabianne A, Fisher Brian T, Hakim Hana, Santolaya Maria E, Castagnola Elio, Davis Bonnie L, Dupuis L Lee, Gison Faith, Groll Andreas H, Gaur Aditya H, Gupta Ajay, Kebudi Rejin, Petrilli Sergio, Steinbach William J, Villarroel Milena, Zaoutis Theoklis E, Sung Lillian: Guidelines for the Management of Fever and Neutropenia in Children with Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation. Journal of Clinical Oncology 30(35): 4427-38, December 2012.

Fisher Brian T, Zaoutis Theoklis E, Park Julie R, Bleakley Marie, Englund Janet, Kane Christine, Arceci Robert J, Guinan Eva, Smith Franklin O, Luan Xianqun, Marr Kieren A: Galactomannan Antigen Testing for Diagnosis of Invasive Aspergillosis in Pediatric Hematology Patients Journal of the Pediatric Infectious Disease Society 1(2): 103-11, June 2012.

Aplenc Richard, Fisher Brian T,  Huang Yuan-Shung, Li Yimei, Alonzo Todd A, Gerbing Robert B, Hall Matt, Bertoch David, Keren, Ron, Seif Alix E, Sung Lillian, Adamson Peter C, Gamis Alan S: Merging of NCI-Funded Cooperative Oncology Group Data with an Administrative Data Source to Develop a More Effective Platform for Clinical Trial Analysis and Comparative Effectiveness Research: A Report from the Children's Oncology Group. Pharmacoepidemiology and Drug Safety 21(Suppl 2): 37-43, May 2012.

2010

Joshi Neha S, Fisher Brian T, Prasad Priya A, Zaoutis Theoklis E: Epidemiology of Cryptococcal Infection in Hospitalized Children. The Pediatric infectious disease journal 29(12): e91-95, Oct 2010.

Fisher Brian T, Zaoutis Theoklis E, Leckerman Kateri H, Localio Russell, Aplenc Richard: Risk factors for renal failure in pediatric patients with acute myeloid leukemia: a retrospective cohort study. Pediatric Blood & Cancer 55(4): 655-61, Oct 2010.

Fisher Brian T, Chiller Tom M, Prasad Priya A, Beveridge Mara, Walsh Thomas J, Zaoutis Theoklis E: Hospitalizations for coccidioidomycosis at forty-one children's hospitals in the United States. The Pediatric infectious disease journal 29(3): 243-7, Mar 2010.

2009

Fisher Brian T, Aplenc Richard, Localio Russell, Leckerman Kateri H, Zaoutis Theoklis E: Cefepime and mortality in pediatric acute myelogenous leukemia: a retrospective cohort study. The Pediatric infectious disease journal 28(11): 971-5, Nov 2009.

Fisher Brian T, Meaney Peter A, Shah Samir S, Irwin Stacy A, Grady Carol A, Kurup Shobha, Malefho Kolaatamo C S, Jibril Haruna, Steenhoff Andrew P: Antibiotic use in pediatric patients admitted to a referral hospital in Botswana. The American journal of tropical medicine and hygiene 81(1): 129-31, Jul 2009.

1998

Lieberman JM,  Marks W H,  Cohn Steven,  Jaicks Russ,  Woode Lawrence,  Sacchettini  J,  Fisher Brian T,  Moller Beth,  Burns, Gerard: Organ failure, infection, and the systemic inflammatory response syndrome are associated with elevated levels of urinary intestinal fatty acid binding protein: study of 100 consecutive patients in a surgical intensive care unit. Journal of Trauma 45(5): 900-6, November 1998.

1997

Cohn, S. M.,  Fisher, B. T.,  Rosenfield, A. T.,  Cross, J. H.: Resuscitation of pulmonary contusion: hypertonic saline is not beneficial. Shock 8(4): 292-9, Oct 1997.

Cohn S M, Zieg P M, Rosenfield A T, Fisher B T: Resuscitation of pulmonary contusion: effects of a red cell substitute. Critical care medicine 25(3): 484-91, Mar 1997.

1996

Cohn, S. M.,  Fisher, B. T.: Do surgeons have a role as infectious disease consultants? Arch Surg 131(9): 990-3; discussion 994, Sep 1996.

Books

Chapters

2015

Sung Lillian, Fisher Brian T, Koh Andrew Y: Infectious Disease in the Pediatric Cancer Patient. Hematology and Oncology of Infancy and Childhood (8th Edition). Orkin Stuart H, Fisher David E, Ginsburg David, Look Thomas A, Lux Samuel E, Nathan David G (eds.). Elsevier Saunders, 2: 2257-66, 2015.

Fisher Brian T, Dvorak Christopher C, Alexander Sarah: Prevention of Infection. Supportive Care in Pediatric Oncology. Feusner James H, Hastings Caroline A, Agrawal Anurag K (eds.). Springer, Page: 223-46, 2015.

2014

Treat James, Fisher Brian T: Bacterial Infections. Neonatal and Infant Dermatology (3rd Edition). Eichenfield Lawrence F, Drieden Ilona J (eds.). Elsevier Saunders, Page: 155-175, 2014.

Fisher Brian T, Sung Lillian: The Febrile Neutropenic Patient. Textbook of Pediatric Infectious Diseases (7th ed). Cherry J, Harrison G, Kaplan S, Steinbach W, Hotez P (eds.). Elsevier Saunders, Philadelphia, PA, Page: 921-33, 2014.

2012

Fisher Brian T, Bell Louis M: Tularemia. 5-Minute Pediatric Consult (6th ed) Schwartz MW (eds.). Lippincott Williams and Wilkins, Philadelphia, PA, Page: 908-909, 2012.

Fisher Brian T: Tick Fever: Colorado tick fever and endemic relapsing fever  5-Minute Pediatric Consult (6th ed). Schwartz MW (eds.). Lippincott Williams and Wilkins, Philadelphia, PA  Page: 876-77, 2012.

2011

Fisher, Brian T, Lindenauer, Peter K, Feudtner, Chris: In-Hospital Databases. Pharmacoepidemiology. Strom, BL (eds.). John Wiley & Sons Ltd, Page: 244-58, 2011

2009

Fisher BT and Clement P: Sinusitis. Pediatric Practice: Infectious Diseases. Shah SS (eds.). McGraw-Hill Medical, New York, NY, Page: 257-274, 2009.

2008

Fisher BT and Haas EJ: Acute sinusitis and acute otitis media. Pediatric Infectious Diseases Requisites (1st ed). Bergelson J (eds.). Elsevier,Philadelphia, PA, Page: 85-95, 2008.

Posters and Presentations

2018

Miller Tamara P, Getz Kelly D, Jen Emily, Huang Yuan-Shung, Li Yimei, Bagatell Rochelle, Seif  Alix E, Fisher Brian T, Przepiorka Donna, Aplenc Richard: Using laboratory result data from an administrative database to describe accurate adverse event rates during pediatric leukemia therapy. Southeastern Pediatric Research Conference, Atlanta, GA (poster presentation) June 2018.

2017

Calhoun S, Ellis D, Fisher, BT, Zaoutis TE, Downes K: The Use of Posaconazole in Hospitalized Children in the United States. American Society for Microbiology Annual Meeting, New Orleans, LA (poster presentation) June 2017.

Szymczak Julia E, Getz Kelly D, Madding Rachel, Fisher Brian, Raetz Elizabeth, Hijiya Nobuko, Gramatges Maria M, Henry Meret, Mian Amir, Arnold Staci D, Aplenc Richard: Identifying Patient and Family Centered Outcomes Relevant to Inpatient versus At-Home Management of Neutropenia in Children with Acute Myeloid Leukemia  American Society of Pediatric Hematology/Oncology, Annual Meeting, Montreal,Canada (poster presentation) April 2017.

Hricik Lauren, Li Yimei, Getz Kelly, Huang Yuang-Shun, Miller Tamara P, Winestone Lena E, DiNofia Amanda, Mann Jennifer, Seif Alix, Aplenc Richard, Fisher Brian T: Effectiveness Of Anti-Infective Prophylaxis In Children With Down Syndrome Who Are Receiving Chemotherapy For Acute Lymphoblastic Leukemia. American Society of Pediatric Hematology/Oncology, Annual Meeting, Montreal,Canada (poster presentation) April 2017.

2016

Hamdy Rana F, Magun Ella, Saxena Shikha, Cardenas Ana Maria, Fisher Brian T : Bloodstream Infections in Children Following Solid Organ Transplantation. Infectious Disease Society of America, Annual Meeting, New Orleans, LA (poster presentation)   October 2016.

Gerber Jeffery S, Fisher Brian T, Ross Rachael, Bryan Matthew, Localio Russell, Barbadora Karen A, Keren Ron, Hoberman Alejandro, Green Michael, Zaoutis Theoklis: Impact of Antimicrobial Prophylaxis on the Development of Antimicrobial Resistance. Infectious Disease Society of America, Annual Meeting, New Orleans, LA (poster presentation)   October 2016.

Downes Kevin, Cowden Carter, Laskin Benjamin, Gong Wu, Huang Yuan-Shung, Fisher Brian T, Goldstein Stuart, Zaoutis Theoklis: Antibiotic-Associated Acute Kidney Injury in Hospitalized Children. Infectious Disease Society of America, Annual Meeting, New Orleans, LA (oral presentation)   October 2016.

Anatale-Tardiff Laura, Getz Kelly, Xiao Rui, Baddley John, Ostrosky-Zeichner Luis, Pappas Peter G, Zaoutis Theoklis E, Fisher Brian T: A marginal structural approach to measuring the comparative effectiveness of echinocandins vs. fluconazole therapy for the treatment of adult candidemia (MSG-12). Infectious Disease Society of America, Annual Meeting, New Orleans, LA (poster presentation)  October 2016.

Smith RJ, Klieger S, Sulieman S, Berger E, Treat JT, Fisher BT: Outcomes of immunocompromised children undergoing skin biopsy for clinically concerning skin lesions. 42nd Annual Meeting of the Society for Pediatric Dermatology (poster presentation); Minneapolis, MN.  July 14-17 2016.

Gee Jerica, Saxena Shikha, BA,  Klieger Sarah B, Kajon Adriana, Petersen Hans, Zaoutis Theoklis E, Fisher Brian T: Invasive fungal disease in pediatric solid organ transplant recipients  Pediatric Infectious Disease Society Transplant Symposium, Memphis, Tennessee (poster presentation) March 2016.

Fisher Brian T, Danziger-Isakov Lara, Englund Janet, Murray Alistair, Maron Gabriela, Toumanen Elaine, Munoz Flor, Sweet Leigh, Green Michael, Michaels Marian, Halasa Natasha, Dulek Daniel, Herold Betsy, Madan Rebecca Pellett, Gee Jerica, Brozovich Ava, Steinbach William J: Epidemiology and Outcomes of Respiratory Viral Infections in Pediatric Hematopoietic Stem Cell and Solid Organ Transplant Recipients. Pediatric Infectious Disease Society Transplant Symposium, Memphis, Tennessee (oral presentation) March 2016.

Invited Lectures

2018

Fisher BT. "Levofloxacin Prophylaxis In Children With Chemotherapy Related Prolonged Neutropenia: Should We Do It?", Infectious Diseases Society of America Annual Meeting, San Francisco, CA. Oct, 2018.

Fisher BT. "How Should You Treat that Bug? A Debate About Antimicrobial Management in Fever and Neutropenia", American Society for Pediatric Hematology and Oncology Annual Meeting, Pittsburgh, PA. May, 2018.

Fisher BT. "Fungal Infections in Pediatric Hematopoietic Stem Cell Transplants", NIH Workshop of Pulmonary Complications of Pediatric Hematopoietic Stem Cell Transplantation, Bethesda, MD. Apr, 2018.

2017

Fisher BT. "Monotherapy versus Dual Therapy for Invasive Aspergillosis and Mucormycosis: Point-Counterpoint Session", Pediatric Infectious Diseases Transplant Symposium, Memphis, TN. Mar, 2017.

Fisher BT. "Updates Fungal Biomarkers for the Diagnosis of Invasive Fungal Disease in Children", Children's Oncology Group Cancer Control Educational Seminar, Webinar. Jan, 2017.

2016

Fisher BT. "Updates on Non-Invasive Diagnosis of Invasive Mold Disease in Children", Pediatric Academic Societies Meeting, Baltimore, MD. May, 2016.

Fisher BT. "Individualizing Prophylaxis For Children with Leukemia:  Progress Toward Personalized Medicine", International BFM Study Group Annual Meeting, Athens, Greece. Apr, 2016.

Fisher BT. "Epidemiology and Outcomes of Respiratory Viral Infections in Pediatric Hematopoietic Stem Cell and Solid Organ Transplant Recipients". Pediatric Infectious Diseases Transplant Symposium, Memphis, TN. Mar, 2016.

Awards and Honors

2015-2018, Early Career Faculty Honor Roll, The Children's Hospital of Philadelphia, Philadelphia, PA
2008-2010, Faculty Honor Roll, The Children's Hospital of Philadelphia, Philadelphia, PA
2004-2005, Pediatric Resident of the Year, Advocate Christ Medical Center-Hope Children's Hospital, Oak Lawn, IL
1993-1995, Academic Excellence in Athletics, University of Notre Dame, Notre Dame, IN

Editorial and Academic Positions

Editorial Positions

2017, Guest Editor, Journal of the Pediatric Infectious Diseases Society
2014-present, Editorial Board, Pediatric Transplantation
2014-present, Reviewer, Clinical Infectious Diseases
2013-present, Reviewer, Transplant Infectious Diseases
2013-present, Reviewer, Pediatric Infectious Disease Journal
2012-present, Reviewer, JAMA, Pediatrics
2012-present, Reviewer, Journal of the Pediatric Infectious Disease Society
2012-present, Reviewer, American Journal of Transplant
2011-present, Reviewer, Drugs
2011-present, Reviewer, Pediatric, Blood & Cancer
2009-present, Reviewer, Pharmacoepidemiology and Drug Safety

Academic and Institutional Committees

2018-present, Clinical Grant Proposal Success Committee
2017-present, MSCE Comprehensive Exam Grading Committee, Center for Clinical Epidemiology and Biostatistics at the Perelman School of Medicine at the University of Pennsylvania
2016-present, Antibiotic Drug Usage Evaluation Subcommittee
2016-present, Program Evaluation Committee, Division of Pediatric Infectious Diseases
2015-present, Clinical Competency Committee, Division of Pediatric Infectious Diseases
2015-present, Senior Scholar, Center for Clinical Epidemiology and Biostatistics
2014-present, Co-Director, International Pediatric Fungal Network
2014-present, Chair, Infectious Disease Subcommittee, Children's Oncology Group Supportive Care Division

Leadership and Memberships

Memberships in Professional Organizations

International

2014-present, International Pediatric Transplant Association

National

2014-present, Pediatric Transplant Infectious Diseases Working Group
2011-present, Infectious Disease Society of America
2005-present, Pediatric Infectious Diseases Society
 - 2017-present, Fellow, Pediatric Infectious Diseases Society