Immune Dysregulation Program

In children with immune dysregulation disorders, the immune system causes multi-system disease with diverse features. Hyperinflammation, autoimmunity and infections can be manifestations of the child's immune disorder. The Immune Dysregulation Program at Children’s Hospital of Philadelphia (CHOP) provides a single place where families can turn for advanced diagnostics of suspected immune disorders and personalized treatments targeting the unique cause of their child’s symptoms.

Suspected Immune Disorders: Evaluation, Diagnosis and Treatment

Why Choose Us?

If your child is experiencing unexplained symptoms that affect multiple organs and doctors can't tell you why, CHOP's Immune Dysregulation Program can find answers. Our program offers coordinated care from experts in every specialty, state-of-the-art diagnostic and genetic tests, and personalized treatments.

Who We're Here For

The Immune Dysregulation Program is where families should turn when it's suspected that their child suffers from an immune dysregulation disorder, but specialists have been unable to provide a diagnosis or effective treatment. We specialize in:

  • Undiagnosed conditions where an immune disorder is suspected
  • Immune disorders of hyperinflammation
  • Immunodeficiency disorders associated with autoimmunity
  • Genetic autoimmune/autoinflammatory disorders
  • Autoimmunity-associated abnormal blood counts 

Our Programs and Services

In addition to our multidisciplinary Immune Dysregulation Clinic, children treated for immune disorders at CHOP benefit from the availability of many other related clinical programs and services.

Our Team

There's no other pediatric hospital that combines the expertise of so many subspecialists to aid in the evaluation and treatment of children with immune dysregulation disorders.