Robert O. Heuckeroth, MD, PhD

Medical School

MD - Washington University School of Medicine, St. Louis, MO

Residency

Pediatrics - St. Louis Children's Hospital, St. Louis, MO

Fellowship

Clinical Fellow, Pediatric Gastroenterology and Nutrition - St. Louis Children's Hospital, St. Louis, MO

Additional Training

Research Fellow - Washington University School of Medicine, St. Louis, MO

Board Certification

Pediatric Gastroenterology
Pediatrics

Graduate Degree

PhD - Washington University School of Medicine, St. Louis, MO

Papers

2016

Schill EM, Lake JI, Tusheva OA, Nagy N, Bery SK, Foster L, Avetisyan M, Johnson SL, Stenson WF, Goldstein AM, Heuckeroth RO: Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. Developmental Biology. Elsevier, 409(2): 473-88, January 2016 Notes: Our article was featured on the cover of the journal, January 15, 2016.

Lake JI, Avetisyan M, Zimmerman A, Heuckeroth RO: Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton. Developmental Biology. Elsevier, 409(1): 152-65, January 2016.

2015

Avetisyan M, Wang H, Schill EM, Bery S, Grider JR, Hassell JA, Stappenbeck T, Heuckeroth RO: Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury. The Journal of Neuroscience 35(33): 11543-11558, August 2015 Notes: Our article was featured on the cover of the Journal August 19, 2015.

Schrenk S, Schuster A, Klotz M, Schleser F, Lake J, Heuckeroth RO, Kim YJ, Laschke MW, Menger MD, Schafer KH: Vascular and neural stem cells in the gut: do they need each other? Histochem Cell Biol 143(5): 397-410, April 2015.

Books

Chapters

2013

Heuckeroth RO : Hirschsprung disease  Pediatric Neurogastroenterology. Faure C, DiLorenzo C, Thapar N (eds.). Humana Press, New York, Heidelberg, Dordrecht, London  Page: 271-283, 2013.

2009

Heuckeroth RO: Autonomic and enteric nervous system: apoptosis and trophic support during development  Handbook of the Neuroscience of Aging. Patrick R. Hof and Charles V. Mobbs (eds.). San Diego: Academic Press, Page: 147-154, 2009.

Heuckeroth RO: Autonomic and enteric nervous system: apoptosis and trophic support during development  New Encyclopedia of Neuroscience. Squire L (eds.). Page: 791-798, 2009.

1985

Greenspan N, Seiden M, Clevinger B, Nahm M, Lutz C, Bartholow T, Heuckeroth RO, Fine S, Davie J: Idiotypes and anti-idiotypes. Immunity to Cancer  Reif AE, Mitchell MS  (eds.). Academic Press, New York, Page: 253-265, 1985.

Posters and Presentations

Invited Lectures

2016

"Emerging insights into intestinal motility disorders in infancy", NEONATAL UPDATE 2016, Imperial College London at BMA House. November 2016.

Environmental Triggers in Neurogastroenterological Disorders, World Congress of Gastroenterology, Hepatology and Nutrition (WCPGHAN), Montreal, Canada, October 2016.

"The Role of the Enteric Nervous System in the Development of Inflammatory Bowel Disease", Fourth Annual Pediatric Inflammatory Bowel Disease (IBD) Research Day at Weill Cornell Medical Center, New York, NY, September 2016.

"Birth defect prevention and repair: Nerve, guts, and a great environment help us all succeed!", Department of Pediatrics, Grand Rounds, Washington University School of Medicine in St. Louis, St. Louis, MO, April 2016.

"Neuroimmunology, the enteric nervous system and bowel inflammation: Underexplored approaches to preventing inflammation", Immunology Research Affinity Group, The Children's Hospital of Philadelphia, April 2016.

"Life of a physician scientist--Moving a lab", Medical Scientist Training Program, Washington University School of Medicine in St. Louis, St. Louis, MO, April 2016.

2015

"Building A Second Brain: New Strategies to Prevent and Treat Bowel Motility", Children's Research Institute Research Conference, Medical College of Wisconsin, Milwaukee, WI, December 2015.

"Ibuprofen slows migration of enteric nervous system precursor cells increasing the risk of Hirschsprung-like disease in animal models", North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN), Washington D.C., October 2015.

"Lessons from Hirschsprung disease models: Beauty, complexity and many ways to fail", 4th International Symposium on Development of the Enteric Nervous System: Cells, Signals, Genes and Therapy, April 2015.

"Building a beautiful nervous system in the bowel, New ideas about preventing Hirschsprung disease, a serious human birth defect", University of Quebec at Montreal, Montreal Canada, January 2015.