Areas of Expertise:
Very Early-onset inflammatory bowel disease, Inflammatory bowel disease
Locations: Main Campus
Areas of Expertise:
Very Early-onset inflammatory bowel disease, Inflammatory bowel disease
Locations: Main Campus
MD - The Weill Medical School of Cornell University, New York, NY
Pediatrics - Albert Einstein Medical Center, Philadelphia, PA
Pediatrics - Mount Sinai Medical Center, New York, NY
Pediatric Gastroenterology, Hepatology and Nutrition - The Children's Hospital of Philadelphia, Philadelphia, PA
IBD Clinical Research Fellowship - Center for Pediatric Inflammatory Bowel Disease, The Children's Hospital of Philadelphia, Philadelphia, PA
Master of Translational Research - The University of Pennsylvania, Philadelphia, PA
Certificate in Epidemiology and Biostatistics - University of Pennsylvania, Philadelphia, PA
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Maxwell E, Dawany N, Baldassano RN, _ Mamula P, Mattei P, Albenberg L, Kelsen JR: Diverting Ileostomy for the Treatment of Severe, Refractory, Pediatric Inflammatory Bowel Disease. JPGN January 2017.
Zhe Zhang, Ph.D.; Lihua Shi, Ph.D.; Noor Dawany; Judith Kelsen; Michelle A Petri, MD MPH; Kathleen E Sullivan, MD PHD: H3K4 tri-methylation breadth at transcription start sites impacts the transcriptome of systemic lupus erythematosus. Clinical Epigenetics 2016.
Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, Surrey LF, Russo P, Sleight A, Schiffrin E, Gabay C, Goldbach-Mansky R, Behrens EM: Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition. J. Allergy Clin Immunol. November 2016.
Conrad MA1, Stein RE, Maxwell EC, Albenberg L, Baldassano RN, Dawany N, Grossman AB, Mamula P, Piccoli DA, Kelsen JR.: Vedolizumab Therapy in Severe Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis October 2016.
Rosenbaum DG, Conrad MA, Biko DM, Ruchelli ED, Kelsen JR, Anupindi SA: Ultrasound and MRI predictors of surgical bowel resection in pediatric Crohn disease. Pediatr Radiol September 2016.
Rona Yaeger, Manish A. Shah, Vincent A. Miller, Judith R. Kelsen, Kai Wang, Zachary J. Heins, Jeffrey S. Ross, Yuting He, Eric Sanford, Rhonda K. Yantiss, Sohail Balasubramanian, Philip J. Stephens, Nikolaus Schultz, Moshe Oren, Laura Tang, David Kelsen: Genomic Alterations Observed in Colitis-associated Cancers are Distinct from Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease. Gastroenterology April 2016.
David R. Withers*, Matthew R. Hepworth, Xinxin Wang, Emma C. Mackley, Emily E. Halford, Emma E. Dutton, Clare L. Marriott, Verena rucklacher-Waldert, Marc Veldhoen, Judith Kelsen, Robert N. Baldassano, Gregory F. Sonnenberg : Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving ILC3 Nature Medicine January 2016.
Sahn B, Chen-Lim ML, Ciavardone D, Farace L, Jannelli F, Nieberle M, Ely E, Zhang X, Kelsen J, Puma A, Mamula P.: Safety of a 1-Day Polyethylene Glycol 3350 Bowel Preparation for Colonoscopy in Children. JPGN 2015.
Kelsen J, Bittinger K, Pauly-Hubabrd H, Posivak L, Grunberg S, Baldassano R, Lewis J, Wu G, Bushman F: Alterations of the Subgingival microbiota in pediatric Crohn's Disease Studied longitudinally in Discovery and Validation cohorts. Inflammatory Bowel Disease 21(12), December 2015.
Judith R. Kelsen, Noor Dawany, Christopher J. Moran, Mahdi Sarmady, Ariella Sasson, Helen Pauly-Hubbard, Alejuandro Martinez, Kelly Maurer, Joanne Soong Eric Rappaport, Harland S. Winter, Petar Mamula, David A. Piccoli, Mark Daly, David Artis, Gregory F. Sonnenberg, Kathleen E. Sullivan, Robert N. Baldassano, Marcella Devoto: Exome Sequencing Analysis Reveals variants in Primary Immunodeficiency Genes in Very Early Onset Inflammatory Bowel Disease. Gastroenterology 149(6): 1415-24, Nov 2015.
Judith R. Kelsen, MD1, Noor Dawany, PhD,2 Alejuandro Martinez,1 Christopher M. Grochowski,3 Kelly Maurer, 4 Eric Rappaport, PhD5, David A. Piccoli, MD1 Robert N. Baldassano, MD1, Petar Mamula, MD1, Kathleen E. Sullivan, MD, PhD4, Marcella Devoto, PhD6: A de novo whole gene deletion of XIAP Detected by Exome Sequencing Analysis in Very Early Onset Inflammatory Bowel Disease. BMC Gastroenterol 15, November 2015.
Hepworth, Mauser, Kelsen, Baldassano, Sonnenberg: Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD+4 T cells." Science April 2015.
Sahn B, Anupindi SA, Dadhania NJ, Kelsen JR, Nancy ML, Mamula P: Duodenal Hematoma Following EGD: Comparison with Blunt Abdominal Trauma-Induced Duodenal Hematoma. JPGN 60(1), Jan 2015.
Gupta K, Noble A, Kachelries KE, Albenberg L, Kelsen JR, Grossman AB, Baldassano RN: A novel enteral nutrition protocol for the treatment of pediatric Crohn's disease. Inflamm Bowel Dis 19(7): 1374-8, June 2013.
Christopher J. Cardinale, Judith R. Kelsen, Robert N. Baldassano, and Hakon Hakonarson: The Impact of Exome Sequencing in Inflammatory Bowel Disease. World Journal of Gastroenterology In press 2013.
Judith Kelsen, Gary Wu: The gut microbiota, environment and diseases of modern society Gut Microbes. Landes Bioscience, 3(4), July 2012 Notes: Epub ahead of print.
Lindsey Albenberg, Petar Mamula, Judith Kelsen: Biologics for the treatment of moderate-severe ulcerative colitis in pediatric patients. Pediatric Health, Medicine and Therapeutics. Dove Press, In print, 2012.
Dige A, Hvas CL, Deleuran B, Kelsen J, Bendix-Stuve M, Dahlerup JF, et al. Adalimumab treatment in Crohn's disease does not induce early changes in regulatory T cells. Scand J Gastroenterol. 2011 Oct;46(10):1206-14. Epub 2011 July 27. Cited in PubMed; PMID 21793633. Read the abstract
Kelsen J, Dige A, Schwindt H, D'Amore F, Pedersen FS, Agnholt J, et al. Infliximab induces clonal expansion of yδ-T cells in Crohn's disease: a predictor of lymphoma risk: PLoS One. 2011 Mar 31;6(3):e17890. Cited in PubMed; PMID 21483853. Read the article
Kelsen JR, Kim J, Latta D, Smathers S, McGowan KL, Zaoutis T, et al. Recurrence rate of clostridium difficile infection in hospitalized pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis. 2011 Jan;17(1):50-5. Doi: 10.1002/ibd.21421. Epub 2010 Aug 18. Cited in PubMed; PMID 20722068. Read the article
Jørgensen SP, Agnholt J, Glerup H, Lyhne S, Villadsen GE, Hvas CL, et al. Clinical trial: vitamin D3 treatment in Crohn's disease - a randomized double-blind placebo-controlled study. Aliment Pharmacol Ther. 2010 Aug;32(3):377-83. Epub 2010 may 11. Cited in PubMed; PMID 20491740. Read the abstract
Kelsen JR, Rosh J, Heyman M, Winter HS, Ferry G, Cohen S, et al. Phase I trial of sargramostim in pediatric Crohn's disease. Inflamm Bowel Dis. 2010 Jul;16(7):1203-8. Epub 2010 Jan 5. Cited in PubMed; PMID 20052780. Read the article
Conrad MA, Dawany N, Bittinger K, Baldassano RN, Piccoli D, Bushman FD, Devoto M, Kelsen JR : Characterization of the Intestinal Microbiome in Very Early Onset Inflammatory Bowel Disease Digestive Disease Week Annual Meeting, San Diego, CA May 2016.
Kelsen JR, Dawany N, Conrad, MA, Martinez A, Artis D, Sonnenberg GF, Mamula P, Piccoli DA, Baldassano RN, Sullivan KE, Devoto M: SU1851 Transcriptome Analysis Elucidates the Relevance of WES-Identified Variants in Patients with VEO-IBD. Gastroenterology 150(4): S570, April 2016.
Kelsen J, Dawany N, Conrad M, Martinez A, Mamula P, Piccoli D, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto M: 0-003 Understanding the Relevance of Whole Exome Sequencing Identified Variants in Patients with Very Early-Onset-IBD. Inflamm Bowel Dise 22 Suppl 1: S1-2, Mar 2016.
Yaeger R, Miller V, Kelsen JR, Wang K, Tang L, Kelsen D: Clinically relevant genomic alterations are frequent in Colitis Associated Cancers. ASCO 2015.
Kelsen J, Albenberg L, Bailey A, Bittinger K, Schall1 J, Mascarenhas M, Bushman FD, and Stallings G : 16S Gene Sequencing Reveals a Unique Bacterial Signature in the Gut Microbiota of Pediatric Patients with Cystic Fibrosis. Digestive Disease week 2015.
Conrad M, Stein R, Maxwell E, Grossman A, Albenberg L, Baldassano R, Piccoli D, Kelsen J: Vedolizumab for Treatment of Severe Pediatric Inflammatory Disease. Digestive Disease Week 2015 2015 Notes: Oral presentation by collaborator Stein R.
Moran C, Kelsen J, Kaplan J, Baril-Dore1 M; Schindelar L; Kirschner B, Baldassano R,Xavier R, Winter H, Daly M, PhD5: Whole Exome Sequencing in Very Early Onset Inflammatory Bowel Disease. North American Society for Pediatric Gastroenterology Hepatology and Nutrition Annual Meeting, Chicago, IL October 2013.
Fish S, Wei Z, Bradfield J, Hakonarson H, Baldassano R, Kelsen J: SLC11A1 Polymorphism Increases the Risk of Early Surgery in Pediatric Patients With Inflammatory Bowel Disease. Oral Abstract, North American Society for Pediatric Gastroenterology Hepatology and Nutrition Annual Meeting, Chicago, IL October 2013 2013.
Jump C, Loomes KM, Piccoli DA, Blinman TA, Rosh J, Anupindi S, Smith-Whitley K, and Kelsen JR: "Role of Colectomy to Treat Life-Threatening Thrombotic Storm in Pediatric IBD" North American Society for Pediatric Gastroenterology Hepatology and Nutrition Annual Meeting, Chicago, IL October 2013.
Sahn B, Kelsen J, Maltman S, Stanley N, Mamula: A prospective randomized comparison of air and carbon dioxide insufflation in pediatric colonoscopy. J Pediatr Gastroenterol Nutr 55(Suppl 1 E 18), 2012.
J Kelsen1, L Posivak1, S Grunberg2, A Bailey2, R Baldassano1, JD Lewis4, FD Bushman2 GD Wu4 : "The Oral Microbiome in Pediatric Crohn's Disease," Advances in IBD, CCFA annual conference, Fort Lauderdale, Fl. Inflammatory Bowel Disease December 2012.
Menard C, Kelsen J: Perianal Abscess in Children. The 5-Minute Pediatric Consult. LWW, 6, 2012.
Kelsen J, Markowitz J: Ulcerative Colitis in Children. The 5-Minute Pediatric Consult. LWW, 6, 2012.
Judith Kelsen, Maria Mascarenhas: Upper Gastrointestinal Bleeding. Five Minute Pediatric Consult. Schwartz, Bell, Bingham, Friedman, Loomes, Mamula, Mascarenhas, Tanel (eds.). LWW, 6: 886-887, 2012.
Judith Kelsen, Gary Wu: The Gut Microbiota and IBD. Pediatric Inflammatory Bowel Disease. Mamula, Baldassano, Markowitz (eds.). Springer, 2, In print 2012.
Judith Kelsen, Andrew Mulberg: Imperforate Anus. Five Minute Pediatric Consult. Schwartz, Bell, Bingham, Friedman, Loomes, Mamula, Mascarenhas, Tanel (eds.). LWW, 6, 2012.
Albenberg L, Mamula P, Kelsen J: Biologics for the treatment of moderate to severe ulcerative colitis in pediatric patients. Pediatric Health, Medicine and Therapeutics 3: 51-8, 2012.
Albenberg L, Kelsen J, Baldassano RN: Pediatric Considerations in Medical Therapy in Patients with ulcerative colitis, The Complete Guide to Medical Management. Medical Therapy of ulcerative colitis. Gary Lichenstein (eds.). Springer, 2, In print 2012.
Lindsey Albenberg, Judith Kelsen, Robert Baldassano: Pediatric Considerations in Medical Therapy in Patients with Crohn's Disease, The Complete Guide to Medical Management. Medical therapy for Crohn's Disease. Lichenstein (eds.). Springer, 3, 2011.
Kelsen J, Hunter A, Baldessano RN: Pediatric therapies in inflammatory bowel disease. Advanced Therapy in Inflammatory Bowel Disease. Theodore M. Bayless and Stephen B. Hanauer (eds.). People's Medical Publishing House, 1, 2011.
Kelsen J, Baldassano RN, : Pediatric Considerations in Medical Therapy in Patients with Ulcerative Colitis. Medical Therapy in Patients with Ulcerative Colitis, The Complete Guide to Medical Management. Gary Lichenstein (eds.). 2, 2011.
Anna Hunter, Judith Kelsen, Robert Baldassano: Crohn's disease therapy in Children and Adolescent. Advanced Therapies In Inflammatory Bowel Disease. Theodore M. Bayless (eds.). 3, 2011.
Kelsen J, Mamula P: Ulcerative Colitis in Children. eMedicine from WebMD March 2011.
Anupindi S, Ayyala R, Kelsen J, Mamula P, Applegate K: Imaging of inflammatory bowel disease in children. Evidence-Based Imaging in Pediatrics. Medine, Appelgate, Blackmore (eds.). Springer Page: 487-505, 2010.
Kelsen J, Mascarenhas M. Upper gastrointestinal bleeding, In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p. 886-887.
Kelsen J, Mulberg A. Imperforate anus. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p. 444-445.
Kelsen J, Mulberg A. C1 esterase inhibitor. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008.
Kelsen J, Mascarenhas M, Short bowel syndrome. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p. 774-775.
Kelsen JR, Dawany N, Conrad M, Giraudo C, Behrens E, Devoto M, Sullivan KE,: "A Diagnostic Approach of Immune Dysregulation in Very Early-Onset IBD" Oral abstract, Advances in IBD, Orlando Florida. IBD 2016.
Kelsen J Dawany, N, Moran C, Winter D, Daly M, Rappaport E, Mamula P, Piccoli P, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto, M: Autosomal recessive model of transmission in VEO-IBD using WES. Oral Abstract DDW 2015.
"Novel Molecular Defects Associated with Very Early Onset Inflammatory Bowel Disease." American Academy of Allergy and Immunology Annual Conference, Atlanta GA, March 2017.
Very Early-onset IBD, It is the Genes!, Gastroenterology Grand Rounds, Columbia University, NY NY, September 2016.
The Ethics of Genetic Studies in IBD, DDW 2016, San Diego, Ca, May 2016.
The Genomic architecture of VEO-IBD, Visiting Young Investigator, Division of Pediatric GI, Baylor College of Medicine, Texas Children's Hospital, May 2016.
Genes, gut microbiome and diet in pediatrics IBD, Grand Rounds, Lancaster Medical Center, Lancaster, PA, April 2016.
The Role of Genetics, Diet and the Gut Microbiome in Pediatric Inflammatory Bowel Disease, The Italian Pediatric Society Annual Conference, Rome Italy, June 2015.
"Genomics and IBD, what have we learned from very early-onset IBD," Great debates in IBD, San Francisco, CA, March 2015., March 2015.
2014, Young Faculty Investigator Award, The North American Society for Gastroenterology, Hepatology and Nutrition
2009, Komarov Research Competition, Clinical Sciences, 3rd place
2009, We Care Digestive Disease Week Travel Grant
2008, North American Society for Pediatric Gastroenterology Hepatology, and Nutrition Travel Grant
2013-present, JPGN, Ad Hoc reviewer
2012-present, PLOS ONE, Ad Hoc reviewer
2009-present, American Journal of Gastroenterology, Ad Hoc Reviewer
2008-present, Inflammatory Bowel Diseases, Ad Hoc Reviewer
2016-present, CHOP Antibiotics DUE subcommittee
2016-present, Clinic Trials Workgroup
2014-present, CHOP Therapeutics and Standards Committee
2006-present, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
- 2015, IBD Committee
- 2012, Professional Education Committee
2010-present, The Crohn's and Colitis Foundation of America
2006-present, American Gastroenterological Association (AGA)
2006-present, American Association for the Study of Liver Diseases (AASLD)
2001-present, American Academy of Pediatrics (AAP)