Peter J. Madsen, MD, MBE

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Peter J. Madsen, MD, MBE, is an Attending Neurosurgeon in the Division of Neurosurgery at Children's Hospital of Philadelphia.

Areas of Expertise: Brain and spinal cord tumors, Congenital spine disorders, Craniofacial disorders, Hydrocephalus, Brain and spine trauma, Peripheral nerve tumors
Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

As a Pediatric Neurosurgeon at the Children’s Hospital of Philadelphia, I have the privilege of treating children and young adults with various conditions of the brain, spine, and peripheral nervous system. I have a broad interest in all aspects of pediatric neurosurgery and provide surgical care for patients with tumors of the brain and spinal cord, congenital spine disorders, craniofacial abnormalities, hydrocephalus, traumatic brain and spine injuries, and tumors of the peripheral nervous system. I strive for a collaborative approach to decision-making as I work closely with patients and their families to find the best possible surgical or non-surgical treatments for their conditions.

I have a particular interest in the care of children and young adults with brain tumors, such as medulloblastoma, ependymoma, AT/RT, diffuse midline glioma, and low-grade glioma. I collaborate with my colleagues in the Pediatric Neuro-Oncology Program at CHOP to treat children and young adults with these challenging diseases. Whether I am caring for a patient with a newly diagnosed brain tumor or meeting with a family seeking a second opinion, the goal is always to achieve the best outcome in the safest way possible that maximizes a patient’s chances for long-term health and happiness. Whenever possible, we strive to use the most advanced and minimally invasive techniques, including microsurgery, endoscopic surgery, and laser interstitial thermal ablation.

While surgery is an important part of the care for patients with brain tumors, it is essential that our team investigate and develop new and comprehensive brain tumor therapies. I spend much of my time pursuing research efforts to develop new, targeted treatments that will hopefully one day spare children from risks of surgery and the side-effects of currently available treatments. I have a particular interest in bringing developments in the field of immunotherapy to the treatment of children and young adults with brain tumors. Through various grants and collaborative partnerships with CHOP neuro-oncologists, I direct laboratory efforts testing CAR-T cell therapies for multiple types of pediatric brain tumors with the hope of translating these approaches into clinical trials.

As a parent myself, I appreciate the level of trust that parents must place in a surgeon when their child needs pediatric neurosurgical care. I am so fortunate to be a part of an incredible team of doctors, nurses, therapists, and support staff at CHOP who are united in providing exceptional care for our patients. This team-based approach that puts children and their families at the center of their care makes all the difference, allowing us to provide the highest quality treatment with compassion and dedication.

Education and Training

Medical School

MD - Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Residency

Neurological Surgery - Hospital of the University of Pennsylvania, Philadelphia, PA

Fellowship

Neurosurgical Oncology and Skull Base Surgery - Wellington Regional Hospital, Wellington, New Zealand
Neurosurgery - Children's Hospital of Philadelphia, Philadelphia, PA

Graduate Degree

Masters of Bioethics - Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Attending Neurosurgeon

Instructor, Division of Neurosurgery, Children’s Hospital of Philadelphia

Instructor, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania

Departments and Services

Publications

Papers

2022

Madsen PJ, Hollawell ML, Santi M, Surrey LF, Vossough A, Orr BA, Tucker AM, Storm PB, Foster JF. Diffuse leptomeningeal glioneuronal tumor in a child masquerading as an intramedullary spinal pilocytic astrocytoma. 2022. In review.

Tucker AM, Madsen PJ, Coyle AM, King H, Zahner C, Lang SS, Taylor JA, Heuer GG. Preprocedural Electrophysiological Monitoring in Craniofacial Surgery for a Patient with Chiari Malformation. Cleft Palate Craniofac J. 2022; epub ahead of print.

Foster JB, Griffin C, Rokita JL, Stern A, Brimley C, Rathi K, Lane MV, Buongervino SN, Smith T, Madsen PJ, Martinez D, Wechsler-Reya RJ, Kariko K, Storm PB, Barrett DM, Resnick AC, Maris JM, Bosse KR. Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors. J. Immunother. Cancer. 2022; 10(9): e004450.

Shaprio JA, …, Madsen PJ, …, Taroni JN. An open pediatric brain tumor atlas. 2022. https://alexslemonadegithub.io/OpenPBTA-manuscript/v/7207b5942e7207c7205... 7254c7204a7278ec7206f7810e/

Punchak MA, Hollawell ML, Viaene AN, Cahill AM, Storm PB, Madsen PJ, Tucker AM. Large scalp venous malformation in a pediatric patient managed with sclerotherapy and surgery: a case report and review of literature. Child’s Nerv Syst. 2022; epub ahead of print.

Rahman RK, Tomlinson SB, Katz J, Galligan K, Madsen PJ, Tucker AM, Kessler SK, Kennedy BC. Stereoelectroencephalography Before Age Two. Neurosurg. Focus. 2022; epub ahead of print.

Fischer KM, Madsen PJ, Tucker AM, Long CJ. Thoracic spinal arachnoid cyst in a pediatric patient presenting with isolated bladder and bowel incontinence. Urol. Case Rep. 2022; 44, epub ahead of print.

Madsen PJ, Rahman RK, Patel YA, Lang SS, Storm PB, Tucker AM. Surgical Management and Outcomes of Intracranial Metastatic Wilms’ Tumor in the Pediatric Population: A Case Series.  Childs Nerv Syst. In production. 

Lang SS, Kumar NK, Madsen PJ, Gajjar AA, Gajjar E, Resnick AC, Storm PB. Neurotrophic tyrosine receptor kinase fusion in pediatric central nervous system tumors. Cancer Genet. 2022; 262-3: 64-70.  

Villavisanis DF, Cho DY, Shakir S, Kalmar CL, Wagner CS, Cheung L, Blum JD, Lang SS, Heuer GG, Madsen PJ, Bartlett SP, Swanson JW, Taylor JA, and Tucker AM. Parietal bone thickness predicts operative transfusion and blood loss in a cohort of patients undergoing spring mediated cranioplasty for nonsyndromic sagittal craniosynostosis. J. Neusorug. Pediatr. 2022; Online ahead of print. 

2021

Lang SS, Gajjar A, Tucker AM, Storm PB, Madsen PJ, O’Brien A, Chiotos K, Kilbaugh T, Huh JW. Urgent neurosurgical interventions in the COVID-19 positive pediatric population. World Neurosurg. 2021; 158:196-205.

Buch VP, Kobina MB, James G, Brian P, Madsen PJ, Borja A, Haldar D, Basenfelder P, Yoon J, Schuster J, Chen HC. Development of an Intraoperative Pipeline for Holographic Mixed Reality Visualization During Spinal Fusion Surgery. Surg. Innov. 2021;28(4):427-437.

Foster JB, Griffin C, Rokita JL, Stern A, Brimley C, Rathi K, Lane MV, Buongervino SN, Smith T, Madsen PJ, Martinez D, Wechsler-Reya RJ, Kariko K, Storm PB, Barrett DM, Resnick AC, Maris JM, Bosse KR. Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors. J. Immunother. Cancer. 2022; 10(9): e004450.

Dimentberg R, Kvint S, Madsen P, Glauser G, Choudhri O. Microsurgical Treatment of a Complex Cognard V Tentorial Dural Fistula with Superior Cerebellar Artery Supply. World Neurosurg. 2021; 146:14.

2020

Madsen PJ, Taylor JA, Heuer GG. Commentary: Craniopagus separation, a model for innovation in surgery. Surgery. 2020; epub ahead of print.

Piazza M, Zadnik-Sullivan P, Madsen PJ, Branche M, McShane B, Saylany A, Sharma N, Arlet V, Ozturk A. Proximal junctional kyphosis following Tl 0-pelvis fusion presenting with neurologic compromise: case presentations and review of the literature. Br J Neurosurg. 2020; epub ahead of print.

Proximal junctional kyphosis following Tl 0-pelvis fusion presenting with neurologic compromise: case presentations and review of the literature. Br J Neurosurg. 2020; epub ahead of print.

Flanders TM, Madsen PJ, Pisapia JM, Hudgins ED, Mackell CM, Alexander EE, Moldenhauer JS, Zarnow DM, Flake AW, Adzick NS, Heuer GG. Improved post-operative metrics with modified myofascial closure in fetal myelomeningocele repair. Oper. Neurosurg. 2020; 18(2): 158-65.

Flanders TM, Heuer GG, Madsen PJ, Buch VP, Mackell CM, Alexander E, Moldenhauer JS, Zarnow DM, Flake AW, Adzick NS. Detailed analysis of hydrocephalus and hindbrain herniation after prenatal and postnatal myelomeningocele closure: Report from a single institution. Neurosurg. 2020; 86(5):637-45.

2019

Heuer GG, Madsen PJ, Flanders TM, Kennedy BC, Storm PB, Taylor JA. A multidisciplinary separation of craniopagus twins. NEJM 2019; 380:358-64.

Ramayya AG, Carrasquilla A, Hitti FL, Madsen PJ, Thawani JP, Sinha S, Kvint S, Kung DK, Schuster J. Non­-traumatic Rupture of the Ligamentum Flavum with Symptomatic Spontaneous Lumbar Epidural Hematoma: A case report. Interdiscip. Neurosurg. 2019; 16:51-3.Foster JB*, Madsen P J*, Hegde M, Ahmed NM, Cole KA, Maris JM, Resnick AC, Storm PB, Waanders AJ. lmmunotherapy for Pediatric Brain Tumors: Past and Present. Neuro Onco. 2019; 21(10):1226-38.

Goldstein HE, Shao B, Madsen PJ, Hartnett SM, Blount JP, Brockmeyer DL, Campbell RM, Conklin M, Hankinson TC, Heuer GG, Jea AH, Kennedy BC, Tuite GF, Rodriguez L, Feldstein NA, Vitale MG, Anderson RCE. Increased complications without neurological benefit are associated with prophylactic spinal cord untethering prior to scoliosis surgery in children with myelomeningocele. Childs Nerv Syst. 2019; 35(11):2187-94.

Madsen PJ, Buch VP, Douglas JE, Parasher AK, Lerner DK; Alexander E, Workman AD, Palmer JN, Lang SS, Kennedy BC, Vossough A, Adappa ND, Storm PB. Endoscopic Endonasal Resection of Pediatric Craniopharyngioma: Comparison to Open Resection with a Focus on Cerebrovascular and Related Complications. J. Neurosurg. Pediatr. 2019; 24(3):236-45. 2019 JNS Editor's Choice - Tumor.

2018

Madsen PJ, Mallela AN, Hudgins ED, Storm PB, Heuer GG, Stein SC. The Effect and Evolution of Patient Selection on Outcomes in Endoscopic Third Ventriculostomy for Hydrocephalus: A Large-Scale Review of the Literature. J. Neural. Sci. 2018; 385: 185-91.

Stewart L, Sinha S, Madsen PJ, Glaser L, Chen I, Culyba MJ. Spinal epidural abscess caused by Gardnerella vagina/is andPrevotella amnii. Infec. Dis. Clin. Pract. 2018; 26(4):237-9.

2017

Buch VP, Madsen PJ, Vaughan KA, Koch PF, Kung DK, Ozturk AK Rotational vertebrobasilar insufficiency due to compression of a persistent first intersegmental artery: A case report. J. Neurosurg. Spine. 2017; 26(2): 199-202.

2016

Thawani JP, Ramayya AG, Abdullah KG, Hudgins E, Vaughan K, Piazza M, Madsen PJ, Buch V, Grady MS. Resident simulation training in endoscopic endonasal surgery utilizing haptic feedback technology. J. ofClin. Neurosci. 2016; 34:112-16.

2013

Madsen PJ, Lang, SS, Pisapia JM, Storm PB, Hurst RW, Heuer GG. An Institutional Series and Literature Review of Pial Arteriovenous Fistulas in the Pediatric Population. J. Neurosurg. Pediatr. 2013; 12( 4):344-50.

Sievert AJ, Lang SS, Boucher KL, Madsen PJ, Slaunwhite EM, Brewington D, Storm PB, Resnick AC. Paradoxical Activation and RAF Inhibitor Resistance of BRAF Fusions Characterizing Pediatric Astrocytomas. PNAS. 2013; 110(15):5957-62.

2012

Stephen JH, Sievert AJ, Madsen PJ, Judkins AR, Resnick AC, Storm PB, Rushing EJ, and Santi M.: Spinal Cord Ependymomas and Myxopapillary Ependymomas in the First Two Decades of Life: A Clinicopathological and Immunohistochemical Characterization of 19 Cases. J. Neurosurg. Pediatr. 2012; 9(6):646-53.

2010

Popescu DL, Vrabel M, Brausam A, Madsen PJ, Lente G, Fabian I, Ryabov AD, van Eldik R, Collins TJ. Thermodynamic, Electrochemical, High-Pressure Kinetic, and Mechanistic Studies of the Formation of Oxo Fe1v-TAML Species in Water. 2010; Inorg. Chem. 49(24):11439-48.

2008

Shappell NW, Vrabel MA, Madsen PJ, Harrington GE, Billey LO, Hakk H, Larsen GL, Beach ES, Horwitz CP, Ro KS, Hunt PG, Collins TJ. Destruction of Estrogens Using Fe-TAML/Peroxide Catalysis. Environ. Sci. Technol. 2008; 42(2): 1296-300.

Books

Chapters

2022

Tucker AM, Madsen PJ, Heuer GG. Ventricular Shunts for Hydrocephalus. Fundamentals of Pediatric Surgery. Cham: Springer. 2022.

Madsen PJ, Lang SS, Adappa ND, Palmer JN, Storm PB.  Pediatric Pituitary Surgery. Otolaryngology Clinics: Pituitary Surgery. Philadelphia: Elsevier. 2022.

2020

Madsen PJ, Kennedy BC. "Initial Evaluation and Management of Patients with Neurosurgical Devices." Management of the Hi-Tech Patient in Emergency, Acute and Critical Care: A Practical Guide to Managing Patients with Hi-Tech Hardware. 2020; In production.

Madsen PJ, Taylor JA, Heuer GG. "Craniopagus Twins." Youmans and Winn Neurological Surgery. 2020; In preparation.

2018

Madsen PJ, Chen HCI, Chen SS. "Neurosurgical Approaches to the Treatment of Muscle Hyperactivity." Muscle Over-activity in Upper Motor Neuron Syndrome: Assessment and Problem Solving.for Complex Cases. Philadelphia: Elsevier, 2018.

Posters and Presentations

2023

Kienzle M, Fainberg N, Silver M, Arena J, Landzberg E, Tucker A, Narula S, Madsen P, Huh J. Cerebral Edema in MOG Antibody Disease Treated with Invasive Multimodal Neuromonitoring. 2023 Critical Care Congress Annual Meeting. Critical Care Medicine. 2023: 51(1), 261.

2022

LaRiviere MJ, Kim M, Maris J, Mosse Y, Fan Y, Dorsey J, Foster J, Madsen PJ, Kline C, Metz JM, Hill-Kayser CE. A review of ultra-high dose rate (FLASH) proton therapy for pediatric cancers. 2022 Children’s Oncology Group Young Investigator Meeting. In review.

Madsen PJ, Stern A, Griffin C, Oehm P, Rengstl B, Flemmig C, Tucker AM, Resnick AC, Storm PB, Foster JB. Adapting Claudin 6 CAR T Cell Therapy for the Treatment of Atypial Teratoid Rhabdoid Tumors. 2022 AANS/CNS Pediatric Section Meeting. Poster presentation.

Coyle A, Graves E, Tucker AM, Pukenas B, Storm PB, Madsen PJ. Middle Meningeal Artery Embolization in the Management of Subdural Hematoma in Medically Complex Pediatric Neurosurgical Patients. 2022 AANS/CNS Pediatric Section Meeting. Oral presentation.

Coyle A, Rathi K, Hollawell M, Beck C, Choudhari N, Madsen PJ, Storm PB, Resnick A, Foster JB, Koptyra M. Cell-free miRNA in cerebrospinal fluid and plasma as a diagnostic tool for pediatric brain tumors. 2022 AANS/CNS Pediatric Section Meeting. Oral presentation.

Baubet V, Beale DR, Madsen PJ, Patterson L, Foster JB, Viaene A, Santi M, Koptyra M, Resnick AC, Storm PB. Patient-derived, three-dimensional organoid platform for pediatric brain tumor modeling. 2022 AANS/CNS Pediatric Section Meeting. Poster presentation.

Punchak MA, Wathen CA, Hollawell ML, Sarris C, Flanders TM, Madsen PJ, Tucker AM, Heuer GG. Spinopelvic parameters in patients with complex tethered cord: a 15-year single institution experience. 2022 AANS/CNS Pediatric Section Meeting. Poster presentation.

Christina S, Eide JE, Kshirsagar RS, Adappa ND, Palmer JN, Lang SS, Madsen PJ, Storm PB. Endoscopic Endonasal Fenestration and Marsupialization of Cystic Pediatric Craniopharyngioma: Preserving Pituitary Function and One-Year Outcomes. 2022 AANS/CNS Pediatric Section Meeting. Oral presentation.

Punchak MA, Hollawell ML, Viaene AN, Cahill AM, Storm PB, Madsen PJ, Tucker AM. Large scalp venous malformation in a pediatric patient managed with sclerotherapy and surgery: case report and review of literature. 2022 AANS/CNS Pediatric Section Meeting. Poster presentation.

Madsen PJ, Stern A, Griffin C, Oehm P, Rengstl B, Flemmig C, Resnick AC, Storm PB, Foster JB. Targeting claudin 6 with CAR T cell therapy for atypical teratoid/rhabdoid tumor. 2022 Society for Neuro-Oncology Annual Meeting. Poster presentation.

Madsen PJ, Stern A, Griffin C, Oehm P, Rengstl B, Flemmig C, Tucker AM, Resnick AC, Storm PB, Foster JB. Claudin 6 expression in atypical teratoid/rhabdoid tumors is a target for CAR-T cell therapy. 2022 Meeting of the Congress of Neurologic Surgeons. Oral presentation.

Coyle Anne, Rathi K, Koptyra M, Foster JB, Hollawell M, Beck C, Choudhari N, Storm PB, Resnick AC, Tucker AM, Madsen PJ. Predicting Progression and Recurrence of Pediatric Low Grade Gliomas using miRNA Composition in Plasma and CSF. 2022 Meeting of the Congress of Neurologic Surgeons. Oral presentation.

Blue R, Doiphode N, Jena R, Madsen PJ, Lee J, Shi J, Buch V. Designing and Developing a Novel Deep Computer Vision Platform for Intraoperative Prediction and Analytics. 2022 Meeting of the Congress of Neurologic Surgeons. Oral presentation.

Madsen PJ, Rahman R, Patel Y, Lang SS, Storm PB, Tucker AM. Surgical Management and Outcomes of Intracranial Metastatic Wilms’ Tumor in the Pediatric Population. 2022 Meeting of the Congress of Neurologic Surgeons. Poster presentation.

Rahman RK, Tomlinson SB, Katz J, Galligan K, Madsen PJ, Tucker AM, Kessler SK, Kennedy BC. Stereoelectroencephalography Before Age Two. 2022 American Epilepsy Society.  Poster presentation.

Baubet V, Beale DR, Jacob F, Santi M, Viaene A, Madsen PJ, Koptyra M, Song H, Storm PB, Resnick AC. Development of a patient-derived, three-dimensional organoid platform for pediatric brain tumor modeling. 2022 International Symposium on Pediatric Neuro-oncology. Neuro-Oncology. 2022; 24(sup. 1): i175.

Koptyra M, Baubet V, Beale D, Patterson L, Hollawell M, Biluck I, Beck C, Sonawane P, Griffin C, Stern A, Lilly J, Mason J, Trooskin G, Sullivan C, Morgan A, Frenkel B, Lehmann K, Lopez L, Agbodza E, Nguyen T, Lopez-Gil V, Horsey I, Helili Z, Plisiewicz A, Coleman N, Patton T, Stefankiewicz S, Arya K, Velasco R, Foster J, Madsen P, Viaene A, Santi M,  Storm P, Resnick A. Children’s Brain Tumor Network preclinical tumor models development and sharing platform: collaborative model empowering pediatric brain tumor discovery and global research. 2022 International Symposium on Pediatric Neuro-oncology. Neuro-Oncology. 2022; 24(sup. 1): i175-6.

Foster JB, Griffin C, Stern A, Madsen PJ, Storm PB, Resnick AC. Safely targeting GD2 in thalamic diffuse midline glioma with mRNA CAR T cells. 2022 International Symposium on Pediatric Neuro-oncology. Neuro-Oncology. 2022; 24(sup. 1): i86.

Naqvi AS, Ennis BM, Jin R, Gaonkar KS, Foster JB, Conkrite KL, Rathi KS, Kraya AA, Sonawane P, Madsen PJ, Storm PB, Resnick AC, Rokita JL. CLK1 aberrant splicing in pediatric high-grade gliomas disrupts key oncogenic transcriptional programs. 2022 International Symposium on Pediatric Neuro-oncology. Neuro-Oncology. 2022; 24(sup. 1): i74.

Coyle A, Rathi K, Hollawell M, Beck C, Choudhari N, Smith T, Madsen PJ, Storm PB, Resnick AC, Foster JB, Koptyra M. Composition of cell-free miRNA in cerebrospinal fluid and plasma as a monitoring tool for pediatric brain tumors. 2022 International Symposium on Pediatric Neuro-oncology. Neuro-Oncology. 2022; 24(sup. 1): i157.

Villavisanis DF, Cho DY, Shakir S, Kalmar CL, Wagner CS, Cheung L, Blum JD, Lang SS, Heuer GG, Madsen PJ, Bartlett SP, Swanson JW, Taylor JA, Tucker AM. Parietal Bone Thickness Predicts Intraoperative Blood Loss and Transfusion in Patients Undergoing Spring Mediated Cranioplasty for Non-Syndromic Sagittal Craniosynostosis. 67th Annual Meeting of the Plastic Surgery Research Council. Oral presentation.

Lang SS, Gajjar AA, Rhaman RK, Patel Y, Sharma S, Ellen J, Tucker AM, Heuer GG, Kennedy BC, Flanders TM, Madsen PJ, Storm PB, Zhao C, Huh JW. Risk factors for seizure as a presenting sign in patients with shunt malfunctions. 2022 Meeting of the American Association of Neurological Surgeons. Poster presentation.

Lang SS, Gajjar AA, Tucker AM, Storm PB, Rahman RK, Madsen PJ, O’Brien A, Chiotos K, Kilbaugh TJ, Huh JJ. Urgent Neurosurgical Interventions in the COVID-19 Positive Pediatric Population. 2022 Meeting of the American Association of Neurological Surgeons. Poster presentation.

Villavisanis, DF, Shakir S, Cho D, Zhao C, Kalmar CI, Barrero C, Wagner CS, Blum JD, Cheung L, Chen SS, Heuer GG, Madsen PJ, Swanson JW, Bartlett SP, Taylor JA, Tucker AM. Predicting Changes in Cranial Index Following Spring Mediated Cranial Vault Expansion in Non-Syndromic Sagittal Craniosynostosis: Stepwise and Machine Learning Algorithm Approach. 2022 Meeting of the American Association of Neurological Surgeons. Oral presentation: Top Abstracts.

Ramayya AG, Franco A, Madsen PJ, Kennedy BC. Hemispherotomy abolishes crossover phenomena in transcranial motor evoked potentials. 2022 Meeting of the American Association of Neurological Surgeons. Poster presentation.

Wojcik K, Lecron J, Galligan K, Ramayya A, Madsen PJ, Lang SS, Storm PB, Kessler S, Kennedy BC. Hemispherotomy for Post-Traumatic Epilepsy. 2022 Meeting of the American Association of Neurological Surgeons. Oral presentation.

2019

Buch VP, Park BJ, Mensah-Brown K, Genni J, Madsen PJ, Quattrone F, Morley C, Choudhry 0, Schuster JM, Chen HI. Intraoperative Mixed Reality Holographic Visualization during Spinal Fixation: Early Insights. 2019 Meeting of the American Association of Neurological Surgeons. Oral presentation.

2018

Taylor JA, Madsen PJ, Kennedy BC, Storm PB, Heuer GG. A Multidisciplinary and Innovative Separation of Craniopagus Twins. 2018 Biennial Congress of the European Society of Pediatric Neurosurge1y. Oral presentation.

Taylor J, Madsen PJ, Kennedy BC, Storm PB, Heuer G: A Multidisciplinary and Innovative Separation of Craniopagus Twins. 2018 European Society for Pediatric Neurosurgery. Oral presentation.

Madsen PJ, Han HJ, Liu G, Sonawane P, Menschik AI, Raman P, Waanders AJ, Storm PB, Resnick AC. ACVRI-mutant DIPGs are characterized by aberrant activin-mediated BMP signaling but may lack cytotoxic response to targeted A CVR I -receptor inhibition. 2018 Meeting of the American Association of Neurological Surgeons. Poster presentation.

Madsen PJ, Zhang B, Wang K, Waanders AJ, Storm PB, Resnick AC. In silico identification of neo-antigens in a high-grade pediatric brain tumor cohort utilizing next-generation sequencing: pilot study of a discovery pipeline for immunotherapy targets. 2018 Meeting of the American Association of Neurological Surgeons. Oral presentation. AANS/CNS Tumor Section, Columbia Softball Charity Award.

Heuer GG, Flanders TM, Madsen PJ, Kennedy BC, Storm PB, Taylor JA. A novel multidisciplinary approach to craniopagus twin separation. 2018 Neurosurgical Society of America Annual Meeting. Oral presentation.

Flanders TM, Heuer GG, Madsen P, Mackell C, Alexander E, Moldenhauer J, Zarnow D, Flake A, Adzick NS. Analysis of hydrocephalus and Chiari malformation after prenatal and postnatal myelomeningocele closure: report from a single institution. 2018 Meeting of the American Association of Neurological Surgeons. Oral presentation.

Flanders TM, Heuer GG, Madsen P, Mackell C, Alexander E, Moldenhauer J, Zarnow D, Flake A, Adzick NS. Modified myofascial technique for open fetal myelomeningocele repair results in improved outcomes. 2018 Meeting of the American Association of Neurological Surgeons. Poster presentation.

Awards and Honors

2022-24 CHOP K-Readiness Pilot Program
2022 – 2023 Neurosurgery Research & Education Fund Young Clinician Investigator Award
2022 – 2023 American Society of Spine Radiology Grant
2020, Penn Health Tech Pilot Award
2018, AANS/CNS Tumor Section, Columbia Softball Charity Award
2012-2013, Class of 1949 Medical Student Scholarship
2011, CHOP Pediatric Neurosurgery Medical Student Fellows Research Program
2009-2013, Samuel Bellet Scholarship, University of Pennsylvania, Center for Bioethics
2009, Kevin Heaney and Judi Marvel Brain Tumor Research Fellowship
2008-2012, Schlesinger Medical Student Scholarship
2008, University Honors, Carnegie Mellon University
2008, Sigma Xi, Research honor society
2008, Senior Leadership Award, Carnegie Mellon University
2007, HHMI Undergraduate Student Research Travel Award

Leadership and Memberships

Memberships in Professional Organizations

2022 – present Society for Neuro-Oncology
2021 – present Investigator, Philadelphia Coalition for a Cure
2019 – 2021 AANS/CNS Joint Section on Pediatric Neurological Surgery, Communications Subcommittee Member
2018 – present Investigator, Pacific Neuro-Oncology Consortium (PNOC)
2013 – present Pennsylvania Neurosurgical Society
2013 – present  Congress of Neurological Surgeons
2012 – present American Academy of Neurological Surgery
2011 – present AANS/CNS Joint Section on Pediatric Neurological Surgery