Background

Michael Padula, MD, MBI, FAAP, is medical director of Informatics for the Division of Neonatology at The Children's Hospital of Philadelphia, and a professor of Clinical Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.

He serves as an attending neonatologist in the Newborn/Infant Intensive Care Unit and Special Delivery Unit, which is part of the Center for Fetal Diagnosis and Treatment. He also works in the Intensive Care Nursery at the Hospital of the University of Pennsylvania.

Dr. Padula is actively involved in the education and training of medical students, residents and fellows. His clinical interests include prediction and detection of neonatal infections, neonatal resuscitation and neurodevelopmental outcome. He is also a clinical informaticist with interests in standards and interoperability, data modeling and clinical decision support.

He serves on the executive committee of the Children's Hospitals Neonatal Consortium (CHNC), which focuses on improving outcomes for infants receiving care at tertiary Neonatal ICUs, and created the Children's Hospitals Neonatal Database (CHND) in conjunction with the Children's Hospital Association.

Dr. Padula is co-chair of the of Health Level Seven (HL7) Child Health Work Group, contributing to interoperability standards for Electronic Health Record Functional Profiles and Clinical Document Architecture (CDA) used in quality reporting and health information exchange.

He also serves on the Pediatric Terminology Governance Committee, an initiative of the National Institute of Child Health and Development (NICHD) and Pediatric EHR Data Sharing Network (PEDSNet) supporting terminology harmonization.

Regionally, Dr. Padula serves on the Technical Standards Committee of the HealthShare Exchange of Southeastern Pennsylvania (HSX of SE PA), a collaborative initiative supporting the development of a Health Information Exchange (HIE) among the acute care hospitals and healthcare plans of the Greater Philadelphia region.

Dr Padula earned his bachelor's degree from the Princeton University and his medical degree from Jefferson Medical College. He holds a Masters in Biomedical Informatics degree from Oregon Health & Science Univeristy.

He completed his pediatric residency at A.I. duPont Hospital for Children and Thomas Jefferson University. Dr. Padula completed his neonatal-perinatal fellowship at The Children's Hospital of Philadelphia and the Hospital of the University of Pennsylvania.

He is board certified in pediatrics and neonatal-perinatal medicine.

Education and Training

Medical School

MD - Jefferson Medical College, Philadelphia, PA

Residency

A.I. duPont Hospital for Children, Wilmington, DE
Thomas Jefferson University Hospital, Philadelphia, PA

Fellowship

The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Neonatal-Perinatal Medicine
Pediatrics

Graduate Degree

MBI – Oregon Health & Science University, Portland, OR

Titles and Academic Titles

Attending Neonatologist

Medical Director of Informatics, Division of Neonatology

Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Neonatal infections
Neonatal resuscitation
Neurodevelopmental outcome

Publications

Papers

2019

Ekhaguere OA, Padula MA, Jensen EA.: Use of Point-of-Care Gastric pH Testing to Assess the Efficacy of Acid Suppression Therapy in the Neonatal Intensive Care Unit American Journal of Perinatology Feb 2019 Notes: doi: 10.1055/s-0039-1679917. [Epub ahead of print]

Pellegrin S, Munoz FM, Padula MA, Heath PT, Meller L, Top K, Pressler RM for the Brighton Collaboration Neonatal Seizures Working Group, et al. Neonatal Seizures: Case Definition & Guidelines for Data Collection, Analysis, and Presentation of Immunization Safety Data. Vaccine 2019.

Villagomez AN, Munoz AM, Peterson RL, Colbert AM, Gladstone M, Padula MA, Connery AK for The Brighton Collaboration Neurodevelopmental Delay Working Group, et al. Neurodevelopmental Delay: Case Definition & Guidelines for Data Collection, Analysis, and Presentation of Immunization Safety Data. Vaccine 2019.

Masino AJ, Harris MC, Forsyth D, Ostapenko S, Srinivasan L, Padula MA, et al. Machine learning models for early sepsis recognition in the neonatal intensive care unit using readily available electronic health record data. PLoS One. 2019 Feb 22;14(2):e0212665. doi: 10.1371/journal.pone.0212665. eCollection 2019.

Thom CS, Devine M, Kleinman S, Jensen EA, Lambert MP, Padula MA. Neonatal platelet count trends during inhaled nitric oxide therapy. Br J Haematol. 2019 Dec 15. doi: 10.1111/bjh.16301. [Epub ahead of print] No abstract available. PMID: 31840227 [PubMed - as supplied by publisher]

2018

Lagatta JM, Hysinger EB, Zaniletti I, Padula MA, Zhang H, Grover TR, Engle WA, Murthy K; Children's Hospital Neonatal Consortium Severe BPD Focus Group, et al. The Impact of Pulmonary Hypertension in Preterm Infants with Severe Bronchopulmonary Dysplasia through 1 Year. J Pediatr. 2018 Dec;203:218-224.e3. doi: 10.1016/j.jpeds.2018.07.035. Epub 2018 Aug 29.

Costeloe K, Turner MA, Padula MA, Shah PS, Modi N, Soll R, International Neonatal Consortium, et al. Sharing Data to Accelerate Medicine Development and Improve Neonatal Care: Data Standards and Harmonized Definitions. Journal of Pediatrics Dec 2018.

2017

Tramper J, Zhang H, Foglia EE, Dysart KC, Padula MA, Sullivan KV, Jensen EA. The association between positive tracheal aspirate cultures and adverse pulmonary outcomes in preterm infants with severe bronchopulmonary dysplasia. Am J Perinatol. 2017;34(1):96-104.

Hysinger EB, Friedman NL, Padula MA, Shinohara RT, Zhang H, Panitch HB, Kawut SM. Tracheobronchomalacia is associated with increased morbidity in bronchopulmonary dysplasia. Ann Am Thorac Soc. 2017 Jun 16. doi: 10.1513/AnnalsATS.201702-178OC. [Epub ahead of print]

2014

Massaro AN, Murthy K, Zaniletti I, Cook N, DiGeronimo R, Dizon M, Hamrick SE, McKay VJ, Natarajan G, Rao R, Smith D, Telesco R, Wadhawan R, Asselin JM, Durand DJ, Evans JR, Dykes F, Reber KM, Padula MA, Pallotto EK, Short BL, Mathur AM. Short-term outcomes after perinatal hypoxic ischemic encephalopathy: a report from the Children's Hospitals Neonatal Consortium HIE focus group. J Perinatol. 2014 Nov 13. doi: 10.1038/jp.2014.190. [Epub ahead of print].

Padula, MA; Dewan, ML; Shah, SS; Padula, AM; Srinivasan, L; McGowan, KL; Mahoney, KR; Harris, MC. Risk Factors Associated with Laboratory-confirmed Bloodstream Infections in a Tertiary Neonatal Intensive Care Unit. Pediatr Infect Dis J. 2014 Oct. 33 (10):1027-1032.

Murthy K, Evans JR, Bhatia AM, Rothstein DH, Wadhawan R, Zaniletti I, Rao R, Thurm C, Mathur AM, Piazza AJ, Stein JE, Reber KM, Short BL, Padula MA, Durand DJ, Asselin JM, Pallotto EK, Dykes FD. The association of type of surgical closure on length of stay among infants with gastroschisis born ≥ 34weeks' gestation. J Pediatr Surg. 2014 Aug;49(8):1220-5. Epub 2014 Jan 2.

Grover TR, Brozanski BS, Barry J, Zaniletti I, Asselin JM, Durand DJ, Short BL, Pallotto EK, Dykes F, Reber KM, Padula MA, Evans JR, Murthy K. High surgical burden for infants with severe chronic lung disease (sCLD). J Pediatr Surg. 2014 Aug;49(8):1202-5.

Murthy K, Evans JR, Bhatia A, Rothstein D, Wadwahan R, Zaniletti I, Rao R, Thurm C, Mathur A, Piazza AJ, Stein JE, Reber KM, Short BL, Padula MA, Durand DJ, Asselin JM, Pallotto EK, Dykes FD. The association of type of closure on LOS for infants with gastroschisis born ≥ 34 weeks’ gestation. J Ped Surg. 2014. Epub ahead of print 2014 Jan 06.

Murthy K, Dykes FD, Padula MA, Pallotto EK, Reber KM, Durand DJ, Short BL, Asselin JM, Zaniletti I, Evans JR. The Children’s Hospitals Neonatal Database: An overview of patient complexity, outcomes and variation in care. J Perinatol. 2014 Mar 6. [Epub ahead of print]

Kahn MG, Bailey LC, Forrest CB, Padula MA, Hirschfeld S. Building a common pediatric research terminology for accelerating child health research. Pediatrics. 2014;133(3):516-525.

Murthy K, Savani RC, Lagatta JM, Zaniletti I, Wadhawan R, Truog W, Grover TR, Zhang H, Asselin JM, Durand DJ, Short BL, Pallotto EK, Padula MA, Dykes FD, Reber KM, Evans JR. Predicting death or tracheostomy placement in infants with severe bronchopulmonary dysplasia. J Perinatol. 2014 Mar 20. [Epub ahead of print]