Trusha Patel, MD

Papers

2019

Kelsen JR, Conrad MA, Dawany N, Patel T, Shraim R, Merz A, Maurer K, Sullivan KE and Devoto M. The Unique Disease Course of Children with Very Early Onset-Inflammatory Bowel Disease. Inflammatory Bowel Diseases. Published online September 27, 2019. DOI: 10.1093/ibd/izz214.

2018

Patel TT, Conrad MA, Kelsen JR. Common Threads in Pediatric Inflammatory Diseases: Insight into Personalized Medicine. JAMA Pediatrics. Published online June 18, 2018. doi:10.1001/jamapediatrics.2018.1169

2014

Sun B, Banugaria SG, Prater SN, Patel TT, Fredrickson K, Ringler DJ, de Fougerolles A, Rosenberg AS, Waldmann H, Kishnani PS. Non-depleting anti-CD4 monoclonal antibody induces immune tolerance to ERT in a murine model of Pompe disease. Molecular Genetics and Metabolism Reports. 1(2014):446-450.

2013

Banugaria SG, Prater SN, Patel TT, Dearmey SM, Milleson C, Sheets KB, Bali DS, Rehder CW, Raiman JA, Wang RA, Labarthe F, Charrow J, Harmatz P, Chakraborty P, Rosenbergy AS, Kishnani PS. Algorithm for the early diagnosis and treatment of patients with cross reactive immunologic maternal-negative classic infantile pompe disease: a step towards improving the efficacy of ERT. PLoS One. 8(2013): e67052.

Prater SN*, Patel TT*, Buckley AF, Mandel H, Vladovski E, Banugaria SG, Feeney EJ, Raben N, Kishnani PS. Skeletal muscle pathology of infantile Pompe disease during long-term enzyme replacement therapy. Orphanet Journal of Rare Diseases. 8(2013): 90.

2012

Patel TT, Banugaria SG, Frush DP, Enterline DS, Tanpaiboon P, Kishnani PS. Basilar artery aneurysm: a new finding in classic infantile Pompe disease. Muscle and Nerve. 47(2012):613-615.

Banugaria SG, Patel TT, Kishnani PS. Immune modulation in Pompe disease treated with enzyme replacement therapy. Expert Review of Clinical Immunology. 6(2012):497-499.

Patel TT, Banugaria SG, Case LE, Wenninger S, Schoser B, Kishnani PS. The impact of antibodies in late-onset Pompe disease: a case series and literature review. Molecular Genetics and Metabolism. 106 (2012): 301-309.

Banugaria SG, Patel TT, Mackey J, Das S, Amalfitano A, Rosenberg A, Charrow J, Chen YT, Kishnani PS. Persistence of high sustained antibodies to enzyme replacement therapy despite extensive immunomodulatory therapy in an infant with Pompe disease: Need for agents to target antibody-secreting plasma cells. Molecular Genetics and Metabolism. 105(2012): 677-680.

Books

Chapters

2019

Patel T, Kelsen JR. Gastrointestinal Differential Diagnosis of Food Protein-Induced Enterocolitis Syndrome. In: Food-Protein Induced Enterocolitis Syndrome – Diagnosis and Management, Brown-Whitehorn T, Cianferoni A, editors, Springer, 2019.

Posters and Presentations

2019

Patel T, Conrad MA, Shraim R, Merz A, Maurer K, Dawany N, Devoto M, Behrens E, Bunin NJ, Freedman JL, Giraudo C, Sullivan KE, Kelsen JR. Integration of Clinical, Immunologic and Genomic Data in Children with Very-Early Onset Inflammatory Bowel Disease Leads to Identification of Candidates for Curative Therapy with Stem Cell Transplantation. Oral presentation. Digestive Disease Week. San Diego, CA. May 2019.

Patel T, Conrad MA, Shraim R, Merz A, Maurer K, Dawany N, Devoto M, Behrens E, Bunin NJ, Freedman JL, Giraudo C, Sullivan KE, Kelsen JR. Identifying a Signature of Immune-Mediated Monogenic Defects Amenable to Hematopoietic Stem Cell Transplantation in Very Early Onset Inflammatory Bowel Disease. Oral presentation. Komarov Research Prize Competition. Philadelphia, PA. June 2019.

Patel T, Conrad MA, Moser E, Field NS, Maurer K, Dawany N, Giraudo CC, Henrickson S, Wherry EJ, Devoto M, Bunin NJ, Freedman JL, Heimall J, Arnold DE, Markowitz J, Oliver P, Sullivan KE, Kelsen JR. Novel Treatment of Itch Deficiency in Very Early-Onset Inflammatory Bowel Disease with Hematopoietic Stem Cell Transplantation. Poster Presentation. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Annual Meeting. Chicago, IL. October 2019.

2018

Kelsen J, Conrad M, Dawany N, Merz A, Shraim R, Patel T, Sullivan K, Devoto M, Hamilton K. Understanding Phenotypic Distinctions in Sub-Populations of Very Early-Onset Inflammatory Bowel Disease. Poster Presentation. Digestive Disease Week. Washington, DC. June 2018.

Patel T, Shraim R, Maurer K, Dawany N, Conrad M, Sullivan, K, Kelsen J. Immunophenotyping of Very Early Onset Inflammatory Bowel Disease Patient: Monocyte Subpopulation Analysis. Presented as Poster Presentation. Digestive Disease Week. Washington, DC. June 2018.

2017

Patel T, Conrad M, McDermott J, Dawany N, Devoto M, Sullivan K, Kelsen J. Infantile-Onset Inflammatory Bowel Disease and Lymphoma as a Presentation of IL-10R Deficiency. Abstract Presented as Poster Presentation. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Annual Meeting. Las Vegas, NV. November 2017.