Natalie E. Rintoul, MD Natalie E. Rintoul, MD, is an Attending Neonatologist at CHOP. She co-directs the Neonatal Surgical Team and is Medical Director of the Neonatal ECMO Program. Areas of Expertise: Neonatal ECMO, Neonatal Surgery Locations: Main Campus; CHOP Newborn Care at the Hospital of the University of Pennsylvania Phone: 215-590-1653 Background Natalie Rintoul, MD, is an assistant professor at the University of Pennsylvania School of Medicine and attending neonatologist at The Children's Hospital of Philadelphia. After receiving her medical degree at Queen's University in Canada, Dr. Rintoul completed her pediatric residency at Massachusetts General Hospital in Boston and her neonatal fellowship at The Children's Hospital of Philadelphia. Dr. Rintoul is not only interested in the care of the neonate with congenital anomalies requiring neonatal surgery, but also those neonates requiring heart-lung bypass (ECMO). She is co-director of the Neonatal Surgical Team, and medical director of the Neonatal ECMO Program. She is also a fetal consultant for the Center for Fetal Diagnosis and Treatment. Dr. Rintoul’s research interests include management of myelomeningocele, pulmonary hypoplasia and pulmonary hypertension in congenital diaphragmatic hernia, and perioperative care of the surgical neonate. She is the chair of the Neonatal Perioperative Committee. Dr. Rintoul is also a key member of the Special Delivery Unit, involved in the creation and implementation of delivery room guidelines for infants with congenital anomalies. Education and Training Medical SchoolMD - Queen's University School of Medicine, Kingston, Ontario, Canada ResidencyPediatrics - Massachusetts General Hospital, Harvard University, Boston, MA FellowshipNeonatal-Perinatal Medicine - The Children's Hospital of Philadelphia, Philadelphia, PA Board CertificationNeonatal-Perinatal MedicinePediatrics Titles and Academic Titles Attending NeonatologistCo-director, Neonatal Surgical TeamAssistant Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania Departments and Services Center for Fetal Diagnosis and Treatment Division of Neonatology Pulmonary Hypoplasia ProgramFetal Neuroprotection and Neuroplasticity ProgramNewborn/Infant Intensive Care Unit (N/IICU)Congenital Hyperinsulinism Center Research Interests Myelomeningocele Pulmonary hypertension Pulmonary hypoplasia Perioperative care of the surgical neonate ECMO Neonatal resuscitation Publications Papers2018 Danzer E, Hoffman C, D'Agostino J, Ryan M, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Rate and risk factors associated with autism spectrum disorder in congenital diaphragmatic hernia. Journal of Autism and Developmental Disorders48:2112-2121, 2018. Danzer E, Hoffman C, D'Agostino J, Connelly JT, Waqar LN, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Short-term neurodevelopmental outcome in congenital diaphragmatic hernia: The impact of extracorporeal membrane oxygenation and timing of repair. Pediatric Critical Care Medicine 19:64-74, 2018. Lawrence KM, Berger K, Herkert L, Franciscovich C, O'Dea CLH, Waqar LN, Partridge E, Hanna BD, Peranteau WH, Avitabile CM, Hopper RK, Rintoul NE, Hedrick HL. Use of prostaglandin E1 to treat pulmonary hypertension in congenital diaphragmatic hernia. J Pediatr Surg. 2018 Oct 5;. PMID: 30442461 Lawrence KM, Hedrick HL, Monk HM, Herkert L, Waqar LN, Hanna BD, Peranteau WH, Rintoul NE, Hopper RK. Treprostinil Improves Persistent Pulmonary Hypertension Associated with Congenital Diaphragmatic Hernia. J Pediatr. 2018 May 18. [Epub ahead of print] PMID: 29784517 Riley JS, Antiel RM, Rintoul NE, Ades AM, Waqar LN, Lin N, Herkert LM, D'Agostino JA, Hoffman C, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Reduced oxygen concentration for the resuscitation of infants with congenital diaphragmatic hernia. J Perinatol. 2018 Jun 11. [Epub ahead of print] 2017 Keene S, Murthy K, Pallotto E, Brozanski B, Gien J, Zaniletti I, Hulbert C, Seabrook R, Rintoul N, Chicoine L, Porta N, Grover TR. Acquired Infection and Antimicrobial Utilization During Initial NICU Hospitalization in Infants with Congenital Diaphragmatic Hernia. Pediatr Infect Dis J. 2017 Nov 16. doi: 10.1097/INF.0000000000001835. [Epub ahead of print] Danzer E, Hoffman C, D’Agostino JA, Gerdes M, Bernbaum J, Antiel RM, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcomes at 5 years of age in congenital diaphragmatic hernia. J Pediatr Surg. 2017 Mar;52(3):437-443. Antiel RM, Flake AW, Johnson MP, Khalek N, Rintoul NE, Lantos JD, Curlin FA, Tilburt JC, Feudtner C. Specialty-Based Variation in Applying Maternal-Fetal Surgery Trial Evidence. Fetal Diagn Ther. 2017 Mar 17. Doi:10.1159/000455024 [Epub ahead of print] Gien J, Murthy K, Pallotto EK, Brozanski B, Chicoine L, Zaniletti I, Seabrook R, Keene S, Alapati D, Porta N, Rintoul N, Grover TR. Children's Hospitals Neonatal Consortium CDH Study Group. Short-term weight gain velocity in infants with congenital diaphragmatic hernia (CDH). Early Hum Dev. 2017 Feb 5;106-107:7-12. [Epub ahead of print] 2016 Bamat NA, Tharakan SJ, Connelly JT, Hedrick HL, Lorch SA, Rintoul NE, Williams SB, Dysart KC. Venoarterial extracorporeal life support for neonatal respiratory failure: indications and impact on mortality. ASAIO J. 2016 Dec 13. Doi:10.1097/MAT.0000000000000495 [Epub ahead of print] Danzer E, Gerdes M, D’Agostino JA, Bernbaum J, Hoffman C, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Younger gestational age is associated with increased risk of adverse neurodevelopmental outcome during infancy in congenital diaphragmatic hernia. J Pediatr Surg. 2016 Jul;51(7):1084-90. Partridge EA, Peranteau WH, Herkert L, Rendon N, Smith H, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Right- versus left-sided congenital diaphragmatic hernia: a comparative outcomes analysis. J Pediatr Surg. 2016 Jun;51(6):900-2. Partridge EA, Peranteau WH, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Rate of increase of lung-to-head ratio over the course of gestation is predictive of survival in left-sided congenital diaphragmatic hernia. J Pediatr Surg. 2016 May;51(5):703-5. Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2016 Jan;51(1):28-32. Antiel RM, Riley JS, Cahill PJ, Campbell RM, Waqar L, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Management and outcomes of scoliosis in children with congenital diaphragmatic hernia. J Pediatr Surg. 2016;51(12):1921-1925. 2015 Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Sep;50(9):1477-80. Panitch HB, Weiner DJ, Feng R, Perez MR, Healy F, McDonough JM, Rintoul N, Hedrick HL. Lung function over the first 3 years of life in children with congenital diaphragmatic hernia. Pediatr Pulmonol. 2015 Sep;50(9):896-907. Moldenhauer JS, Soni S, Rintoul NE, Spinner SS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Peranteau WH, Rendon N, Koh J, Howell LJ, Heuer GG, Sutton LN, Johnson MP, Adzick NS. Fetal Myelomeningocele Repair: The Post-MOMS Experience at the Children's Hospital of Philadelphia. Fetal Diagn Ther. 2015;37(3):235-40. Epub 2014 Aug 15. Danzer E, Gerdes M, D’Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2015 Jun;50(6):898-903. Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). J Pediatr Surg. 2015 Feb;50(2):260-2. Read the abstract. Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH. Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Pediatr Surg. 2015 Feb;50(2):263-6. Read the abstract. Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Patient characteristics are important determinants of neurodevelopmental outcome during infancy in giant omphalocele. Early Hum Dev. 2015 Feb 9;91(3):187-193. Read the abstract. Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Feb 23. pii: S0022-3468(15)00131-1. doi: 10.1016. Read the abstract. 2014 Partridge EA, Hanna BD, Panitch HB, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Pulmonary hypertension in giant omphalocele infants. J Pediatr Surg. 2014 Dec;49(12):1767-70. Partridge EA, Bridge C, Donaher JG, Herkert LM, Grill E, Danzer E, Gerdes M, Hoffman CH, D’Agostino JA, Bernbaum JC, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Incidence and factors associated with sensorineural and conductive hearing loss among survivors of congenital diaphragmatic hernia. J Pediatr Surg. 2014 Jun;49(6):890-4. Patient Experience Ratings About the Patient Experience Rating System The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. We are committed to true transparency. 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