Joseph Rossano, MD, loves rising to meet a challenge, and he is dedicated to helping children — that’s why he went into pediatric cardiology.
“Cardiovascular disorders in children can be among the most complex and challenging to treat, and I went into the field to be able to help these children survive and thrive,” Dr. Rossano says.
Dr. Rossano is Chief of the Division of Cardiology at Children’s Hospital of Philadelphia. He is also an Attending Physician in the Cardiac Center and the Cardiac Intensive Care Unit (CICU) and a Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.
“As a clinician, I mostly treat patients with cardiomyopathies (heart muscle diseases), patients who develop advanced heart failure and those who need a heart transplantation,” Dr. Rossano says. “These are complex disorders, and working with our outstanding team here at CHOP and our incredible families is tremendously rewarding.”
A graduate of the University of Arizona College of Medicine, Dr. Rossano won several awards for academic achievement during medical school. He completed his internship and residency at Seattle Children’s Hospital (formerly Children’s Hospital and Regional Medical Center), followed by three fellowships at Baylor College of Medicine and Texas Children’s Hospital. He was trained in pediatric cardiology, heart failure transplantation, and cardiac intensive care.
Dr. Rossano came to Children’s Hospital of Philadelphia in 2011 to help manage the Hospital’s busy heart failure, transplant and cardiac mechanical support programs; train residents and fellows; and conduct research on the epidemiology and outcomes of heart disease in children.
Dr. Rossano is principal investigator or co-investigator on several ongoing research studies. This research includes investigating the use of ventricular assist devices and artificial hearts in children, studying the effectiveness of post-transplant treatments for children who have received heart transplants, an observational study of children with heart failure, and building a registry of pediatric heart transplant patients that aims to further the knowledge of pediatric heart disease and transplantation.
“Our group has an active research program ranging from understanding the fundamental nature of diseases to testing new therapies to evaluating drivers of outcomes and costs,” Dr. Rossano says.
Dr. Rossano has made dozens of presentations at meetings around the world and published over 150 manuscripts in journals such as Circulation, The Journal of the American College of Cardiology, and The Journal of Heart and Lung Transplantation.
Spreading the word about new advances and techniques is part of Dr. Rossano’s commitment to improving outcomes for children with heart disease everywhere. A frequent guest lecturer, he has spoken at children’s hospitals and medical schools across the country on topics ranging from advances in cardiopulmonary resuscitation to postoperative care of patients with ventricular assist devices to heart failure in infants.
As for families whose children are treated at CHOP, Dr. Rossano’s message is this: “We have a large, diverse, and dedicated team that is focused on achieving the best possible outcome for your child.”
MD - University of Arizona College of Medicine, Tucson, AZ
Pediatrics - University of Washington, Children's Hospital and Regional Medical Center, Seattle, WA
Pediatrics - University of Washington, Children's Hospital and Regional Medical Center, Seattle, WA
Pediatric Cardiology - Baylor College of Medicine, Texas Children's Hospital, Houston, TX
Advanced Heart Failure/Cardiac Intensive Care - Baylor College of Medicine, Texas Children's Hospital, Houston, TX
Heart Transplant - Baylor College of Medicine
General PediatricsPediatric Cardiology
MS in Clinical Research - Baylor College of Medicine, Houston, TX
Chief, Division of Cardiology
Attending Cardiologist, Cardiac Center and the Cardiac Intensive Care Unit (CICU)
Co-Director of the Cardiac Center
Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Burstein DS, Griffis H, Zhang X, Cantor RS, Dai D, Shamszad P, Huang YS, Morales DLS, Hall M, Lin KY, O'Connor MJ, Zinn M, Edens E, Parrino E, Kirklin JK, Rossano JW: Resource utilization in children with paracorporeal continuous-flow ventricular assist devices. The Journal of Heart and Lung Transplantation Feb 2021 Notes: In Press.
Burstein DS, McBride MG, Rossano JW, O'Connor MJ, Lin KY, Mascio CE, White R, Iacobellis K, Rosenthal T, Paridon S : Increasing pump speed during exercise training improves exercise capacity in children with ventricular assist devices. ASAIO Journal Apr 2021.
Ahimaz P, Sabatello M, Qian M, Wang A, Miller EM, Parrott A, Lal AK, Chatfield KC, Rossano JW, Ware SW, Parent JJ, Dzwiniel T, Kantor P, Yue L, Wynn J, Lee TM, Addonizio LJ, Appelbaum PA, Chung WK: The impact of genetic testing for cardiomyopathy on emotion well-being and family dynamics: a study of parents and adolescents. Circulation: Genomic and Precision Medicine 2021 Notes: In Press.
Marston NA, Han L, Day SM, Ashley EA, Michels M, Pereira AC, Ingles J, Semsarian C, Jacoby D, Colan SD, Rossano JW, Wittekind SG, Ware JS, Saberi S, Helms AS, Ho CY: Clinical characteristics and cardiovascular outcomes in childhood-onset hypertrophic cardiomyopathy compared with adult-onset disease. European Heart Journal 2021 Notes: In Press.
Ware SM, Wilkinson JD, Tariq M, Schubert JA, Sridhar A, Colan SD, Shi L, Canter CE, Hsu D, Webber SA, Dodd DA, Everitt MD, Kantor PF, Addonizio LJ, Jefferies JL, Rossano JW, Pahl E, Rusconi P, Chung WK, Lee T, Towbin JA, Lal AK, Bhatnagar S, Aronow B, Dexheimer PJ, Martin LJ, Miller EM, Sleeper LA, Razoky H, Czachor J, Lipshultz SE: Genetic causes of cardiomyopathy in children: first results from the pediatric cardiomyopathy genes study. Journal of the American Heart Association 2021 Notes: In Press.
Griffis H, Wu L, Naim MY, Bradley R, Tobin J, McNally B, Vellano K, Quan L, Markenson D, Rossano JW: Characteristics and outcomes of AED use in pediatric cardiac arrest in public settings: the influence of neighborhood characteristics. Resuscitation(146), 126-131, Jan 2020.
Spinner JA, Morris SA, Nandi D, Costarino AT, Marino BS, Rossano JW, Shamszad P: Necrotizing enterocolitis and associated mortality in neonates with congenital heart disease: a multi-institutional study. Pediatric Critical Care Medicine 21: 228-234, Mar 2020.
Lasa JJ, Gaies M, Zhang W, Banerjee M, Alten JA, Butts RJ, Cabrera AG, Cecchia PA, Elhoff J, Lorts A, Rossano JW, Schumacher K, Shekerdemian LS, Price JF for the Pediatric Cardiac Critical Care Consortium (PC4): Epidemiology and outcomes of acute decompensated heart failure in children. Circulation: Heart Failure 13: e006101, Apr 2020.
Miron A, Lafreniere-Roula M, Fan CS, Armstrong KR, Dragulescu A, Papaz T, Manlhiot C, Kaufman B, Butts RJ, Gardin L, Stephenson E, Howard TS, Aziz PF, Balaji S, Ladouceur VB, Benson LN, Colan SD, Godown J, Henderson HT, Ingles J, Jeewa A, Jefferies JL, Lal AK, Mathew J, Jean-St-Michel E, Michels M, Nakano SJ, Olivotto I, Parent JJ, Pereira AC, Semsarian C, Whitehill R, Wittekind SG, Russell MW, Conway J, Richmond ME, Villa C, Weintraub RG, Rossano JW, Kantor PF, Ho CY, Mital S: A validated model for sudden cardiac death prediction in pediatric hypertrophic cardiomyopathy (PRIMaCY). Circulation Apr 2020 Notes: In Press.
Tobin JM, Ramos WD, Greenshields J, Dickinson S, Rossano JW, Wernicki PG, Markenson D, Vellano K, McNally B, and the CARES Surveillance Group: Outcome of Conventional Bystander Cardiopulmonary Resuscitation in Cardiac Arrest Following Drowning. Prehospital and Disaster Medicine(35), 141-147, Apr 2020.
Edelson JB, Griffis H, Burstein DS, Zhang X, Rossano JW, Lin KY, O'Connor MJ: The impact of syndromic genetic disorders on mortality and resource utilization in pediatric hypertrophic cardiomyopathy patients. Pediatric Cardiology May 2020 Notes: In Press.
O'Byrne ML, DeCost G, Katcoff H, Savla JJ, Chang J, Goldmuntz E, Groeneveld PW, Rossano JW, Faerber JA, Mercer-Rosa L: Resource utilization in the first two years following operative correction for tetralogy of Fallot. Journal of the American Heart Association May 2020 Notes: In Press.
Rossano JW, Kantor PF, Shaddy RE, Shi L, Wilkinson JD, Jefferies JL, Czachor JD, Razoky H, Wirtz H, Depre C, Lipshultz SE: Elevated heart rate and survival in children with dilated cardiomyopathy: a multicenter study from the Pediatric Cardiomyopathy Registry. Journal of the American Heart Association Jun 2020 Notes: In Press.
Butto A, Teele SA, Sleeper LA, Thrush PT, Philip J, Lu M, Cantor RS, Rossano JW: The Impact of Pre-Implant Illness Severity on the Outcomes of Pediatric Patients Undergoing Durable Ventricular Assist Device The Journal of Heart and Lung Transplantation 39: 666-674, Jul 2020.
DeWitt AG, Rossano JW, Bailly Dk, Bhat PN, Chanani NK, Kirkland BW, Moga MA, Owens GE, Retzloff LB, Zhang W, Banerjee M, Costarino AT, Bird GL, Gaies M: Predicting and surviving prolonged critical illness after congenital heart surgery: analysis of the Pediatric Cardiac Critical Care Consortium Critical Care Medicine 48: e557-e564, Jul 2020.
VanderPluym CJ, Cantor RS, Machado D, Boyle G, May L, Griffis E, Neibler RA, Lorts A, Rossano J, Sutcliffe DL, Lytrivi ID, Buchholtz H, Fynn-Thompson F, Hawkins B, Conway J: Utilization and outcomes of children treated with direct thrombin inhibitors on paracorporeal ventricular assist device support ASAIO Journal 66: 939-945, Aug 2020.
Burstein DS, Gaynor JW, Griffis H, Ritter A, O'Connor MJ, Rossano JW, Lin KY, Ahrens-Nicklas RC: Genetic variant burden and outcomes in pediatric cardiomyopathy. Pediatric Research 2020 Notes: In Press.
Burstein DS, Rossano JW, Griffis H, Zhang X, Fowler R, Frischhertz BP, Kim YY, Lindenfeld J, Mazurek JA, Edelson JB, Menachem JN: Greater admissions, mortality, and cost of heart failure in adults with congenital heart disease compared to without congenital heart disease. Heart 2020 Notes: In Press.
Edelson JB, Edwards JJ, Katcoff H, Mondal A, Nosheen R, Hanff TC, Griffis H, Mazurek JA, Wald J, Burstein DS, Alturi P, O'Connor MJ, Goldberg JR, Zamani P, Groeneveld P, Rossano JW, Lin KY, Birati E: An increasing burden of disease over the last decade: emergency department visits and subsequent hospitalizations among patients with ventricular assist devices in the United States. Journal of the American Heart Association 2020 Notes: In Press.
Edelson JB, Rossano JW, Griffis H, Quarshie W, Ravishankar C, O'Connor MJ, Mascio CE, Mercer-Rosa L, Glatz AC, Lin KY: Resource use and outcomes of pediatric congenital heart disease admissions: 2003 - 2016. Journal of the American Heart Association 2020 Notes: In Press.
Kauffman H, Ahrens-Nicklas R, Calderon-Anyosa RJC, Lin K, Rossano J, Quartermain M, Banerjee: Genotype-phenotype association by echocardiography offers incremental value in patients with Noonan syndrome with multiple lentigines. Pediatric Research 2020 Notes: In Press.
Lakdawala NK, Olivotto I, Day SM, Han L, Ashley EA, Michels M, Ingles J, Semsarian C, Jacoby D, Jefferies JL, Colan SD, Pereira AC, Rossano JW, Wittekind SG, Ware JS, Cirino AL, Leinwand LA, Seidman CE, Ho CY: Associations between female sex, sarcomere mutations and clinical outcomes in hypertrophic cardiomyopathy. Circulation: Genomic and Precision Medicine 2020 Notes: In Press.
Matsubara D, Kauffman HL, Wang Y, Calderon-Anyosa R, Nadaraj S, Elias MD, White TJ, Torowicz DL, Yubbu P, Giglia TM, Hogarty AN, Rossano JW, Quartermain MD, Banerjee A: Echocardiographic findings with Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 infections: experience from a tertiary care children's hospital in the United States. Journal of the American College of Cardiology 2020 Notes: In Press.
Morales DLS, Adachi I, Peng DM, Sinha P, Lorts A, Fields K, Conway J, St. Louis JD, Koehl D, Jacobs JP, Kirklin JK, Blume ED, Rossano JW: Fourth annual Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs) report. Annals of Thoracic Surgery 2020 Notes: In Press.
Natarajan SS, Stagg A, Taylor AM, Griffis HM, Bosler CK, Cates M, DeWitt AG, Giglia TM, Mascio CE, Ravishankar C, Rossano JW, Taylor LC, Ware EP, Nicolson SC, Rome JJ: Standardization of the peri-operative management for neonates undergoing the Norwood operation for hypoplastic left heart syndrome and related heart defects. Pediatric Critical Care Medicine 2020 Notes: In Press.
Burstein DS, Li Y, Getz KD, Huang YS, Rossano JW, O'Connor MJ, Lin KY, Aplenc R: Mortality, resource utilization and inpatient costs vary among pediatric heart transplant indications: a merged data set analysis from the United Network of Organ Sharing and the Pediatric Health Information System (UNOS-PHIS) databases. Journal of Cardiac Failure Jan 2019.
Burstein DS, Shamszad PS, Dai D, Almond CS, Price JF, Lin KY, O'Connor MJ, Shaddy RE, Mascio CE, Rossano JW: Significant morbidity, mortality and resource utilization associated with advanced heart failure in congenital heart disease in children and young adults. American Heart Journal 209: 9-19, Mar 2019.
Morales DLS, Rossano JW, Vanderpluym C, Lorts A, Cantor R, Miller MA, St. Louis J, Sutcliffe D, Adachi I, Kirklin JK, Rosenthal DN, Blume ED: Third annual pediatric interagency registry for mechanical circulatory support (Pedimacs) report: pre-implant characteristics and outcomes. The Annals of Thoracic Surgery 107: 993-1004, Apr 2019.
White BR, Katcoff H, Faerber JA, Lin KY, Rossano JW, Mercer-Rosa LM, O'Connor MJ: Echocardiographic assessment of right ventricular function in healthy pediatric heart transplant patients with comparison to normal controls. Journal of the American Society of Echocardiography 32: 537-544, Apr 2019.
Naim MY, Griffis HM, Burke RV, McNally BF, Long L, Berg RA, Nadkarni VN, Vellano K, Markenson D, Bradley RN, Rossano JW: Race / ethnicity and neighborhood characteristics are associated with bystander CPR in pediatric out of hospital cardiac arrest in the United States: a study from the Cardiac Arrest Registry to Enhance Survival. Journal of the American Heart Association 16: e012637, Jul 2019.
Burkhart HM, Qureshi MY, Rossano JW, Peral SC, O'Leary PW, Hathcock M, Kremers W, Nelson TJ, and the Wanek HLHS Consortium Clinical Pipeline: Phase I clinical results of autologous stem cell therapy for hypoplastic left heart syndrome: safety and feasibility of intraoperative intramyocardial injections. The Journal of Thoracic and Cardiovascular Surgery 2019 Notes: In Press.
Chambers DC, Cherikh WS, Harhay MO, Hayes D Jr., Hsich E, Khush K, Meiser B, Potena L, Rossano JW, Sadavarte A, Singh TP, Toll AE, Zuckermann A, Stehlik J: The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult lung and heart-lung transplant report - 2019; focus theme: donor and recipient size match. The Journal of Heart and Lung Transplantation 2019 Notes: In Press.
Eberly LA, Day SM, Ashley EA, Jacoby DL, Jefferies JL, Colan SD, Rossano JW, Semsarian C, Pereira PC, Olivotto I, Ingles J, Seidman CE, Channaoui N, Cirino AL, Han L, Ho CY, Lakdawala NK: Association of race with disease expression and clinical outcomes among patients with hypertrophic cardiomyopathy. JAMA Cardiology Dec 2019 Notes: In Press.
Everitt MD, Wilkinson JD, Shi L, Towbin JA, Colan SD, Kantor PF, Canter CE, Webber SA, Hsu DT, Pahl E, Addonizio LJ, Dodd DA, Jefferies JL, Rossano JW, Feingold B, Ware SM, Lee TM, Godown J, Simpson KE, Sleeper LA, Czachor JD, Razoky H, Hill A, Westphal J, Molina KM, Lipshultz SE: Cardiac biomarkers in pediatric cardiomyopathy: study design and recruitment results from the pediatric cardiomyopathy registry. Progress in Pediatric Cardiology 2019 Notes: In Press.
Fox C, Sarkisyan H, Stevens R, Arabia F, Fischer W, Rossano J, Throckmorton A: New versatile dual-support pediatric heart pump. Artificial Organs 2019 Notes: In Press.
Hayes D Jr., Cherikh WS, Chambers DC, Harhay MO, Khush KK, Lehman R, Meiser B, Rossano JW, Hsich E, Potena L, Sadavarte A, Singh TP, Zuckermann A, Stehlik J: The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-second pediatric lung and heart-lung transplant report - 2019; focus theme: donor and recipient size match. The Journal of Heart and Lung Transplantation 2019 Notes: In Press.
Khush K, Cherikh WS, Chambers DC, Harhay MO, Hayes D Jr., Hsich E, Meiser B, Potena L, Robinson A, Rossano JW, Sadavarte A, Singh TP, Zuckermann A, Stehlik: The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult heart transplant report - 2019; focus theme: donor and recipient size match. The Journal of Heart and Lung Transplantation 2019 Notes: In Press.
Lebo CA, Lin KY, Rossano JW: Real-world continuous outpatient physiologic monitoring in pediatric cardiomyopathy patients: a safety and feasibility study. Cardiology in the Young 2019 Notes: In Press.
Raja AA, Shi L, Day Sm, Russell M, Zahka K, Lever H, Colan SD, Margossian R, Hall K, Becker J, Jefferies JL, Patel A, Choudry L, Murphy AM, Canter C, Bach R, Taylor M, Mestroni L, Wheller M, Benson L, Owens A, Rossano J, Lin K, Pahl E, Pereira A, Bundgaard H, Cirino A, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E, Ho CY: Baseline characteristics of the Valsartan for Attenuating Disease Evolution in Early Sacromeric Hypertrophic Cardiomyopathy: a randomized trial. Circulation: Heart Failure 2019 Notes: In Press.
Rossano JW, Singh TP, Cherikh WS, Chambers DC, Harhay MO, Hayes D Jr., Hsich E, Khush K, Meiser B, Potena L, Sadavarte A, Toll AE, Zuckermann A, Stehlik J: The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-second pediatric heart transplant report - 2019; focus theme: donor and recipient size match. The Journal of Heart and Lung Transplantation 2019 Notes: In Press.
"Arrhythmogenic Cardiomyopathy" - Panelist, 5th International Conference on Cardiomyopathy in Children; Virtual
"Biomedical Engineering Opportunities in Pediatric Cardiology", Drexel University, School of Biomedical Engineering, Science and Health Systems; Philadelphia, Pennsylvania
"The Disruptive Colleague", Cardiology 2020: 23rd Annual Update on Pediatric and Congenital Cardiovascular Disease; Orlando, Florida
"Current Practice for Pediatric Heart Transplants and the Effects of Perioperative Care", Cardiology 2020: 23rd Annual Update on Pediatric and Congenital Cardiovascular Disease; Orlando, Florida
"Mechanical Support: For Whom and How?", Cardiology 2020: 23rd Annual Update on Pediatric and Congenital Cardiovascular Disease; Orlando, Florida
"Management of Heart Failure with a VAD: Indications and Preoperative Considerations", Congenital Cardiac Anesthesia Society 2020 Annual Meeting; Nassau, Bahamas
"New Approaches to Anticoagulation in the Pediatric VAD Patient", Congenital Cardiac Anesthesia Society 2020 Annual Meeting; Nassau, Bahamas
"VAD Physiology and Early Complications", Congenital Cardiac Anesthesia Society 2020 Annual Meeting; Nassau, Bahamas
"Heart Failure in Congenital Heart Disease", Grand Rounds, Phoenix Children's Hospital, University of Arizona College of Medicine - Phoenix; Phoenix, Arizona Note: cancelled due to COVID-19 pandemic
"Economics, Ethics, Public Policy", Poster Discussant, International Society for Heart and Lung Transplantation 40th Anniversary Meeting and Scientific Sessions; Montreal, Canada; Cancelled Due to COVID-19 Pandemic
"Junior Faculty Clinical Case Reports - Mechanical Circulatory Support", Poster Discussant, International Society for Heart and Lung Transplantation 40th Anniversary Meeting and Scientific Sessions; Montreal, Canada; Cancelled Due to COVID-19 Pandemic
"ISHLT Guidelines on Donor Acceptability", Panelist, Pediatric Heart Transplant Society Webinar
"Treating patients with Cardiomyopathies: Ongoing research and New advances in the Field", Children's Heart Foundation, Webinar
"Danon Day" - Panelist, Rocket Pharmaceuticals; Webinar
"Wisdom on Teams and Culture in Cardiac Care: Culture Starts with Cardiology", American Academy of Pediatrics National Conference and Exhibition 2020, Section of Cardiology and Cardiac Surgery; Virtual Meeting
"Cultural Awareness, Competency, and Humility: Disparities in Pediatric CPR", Survival 2020 Canadian Red Cross; Virtual Meeting
"Pediatric Cardiac Arrest 101: What Every EMSP Provider Needs to Know", EMS-1; Webinar
"Pediatric Resuscitation 101", Citizen CPR Foundation Virtual Summit 2020; Virtual Meeting
Rossano J. "State-of-the-art treatment for advanced heart failure in pediatric cardiovascular conditions." Presented at the 6th Krakow Educational Workshop on Congenital Heart Disease in Poland, May 31-June 1, 2019.
Rossano J. "Evaluation and treatment of dilated cardiomyopathy." Presented at the 6th Krakow Educational Workshop on Congenital Heart Disease in Poland, May 31-June 1, 2019.
Rossano J. "Heart transplantation: Are we getting any better?" Presented at the 6th Krakow Educational Workshop on Congenital Heart Disease in Poland, May 31-June 1, 2019.
2019, Presidential Award for Excellence, American Red Cross
2017, Best Doctors in America
2020-Present, Deputy Editor, Journal of Heart and Lung Transplantation
2018-Present, Reviewer, Journal of Thoracic and Cardiovascular Surgery
2018-Present, Reviewer, Journal of Pediatric Intensive Care
2018-Present, Reviewer, JAMA Cardiology
2018-Present, Reviewer, Archives of Diseases in Childhood
2017-Present Reviewer, Critical Care
2017-Present Reviewer, JAMA Pediatrics
2017-Present Reviewer, New England Journal of Medicine
2017-Present Reviewer, Critical Care Nurse
2017-Present Reviewer, Open Heart
Annals of Thoracic Surgery
Congenital Heart Disease
International Journal of Artificial Organs
American Journal of Cardiology
Journal of Cardiac Failure
2019-2023, Clinical Scientific Advisory Committee Member, FDA funded Pediatric Device Forum P50FD006427 (PI: RJ Levy)
2020-Present, Patient and Family Psychosocial Care through Early Childhood Steering Group Member, Children's Hospital of Philadelphia
2017-Present, Value-Based Care Clinical Advisory Committee Member, Children's Hospital of Philadelphia
2017-Present, Leadership Affinity Group Member, Children's Hospital of Philadelphia
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