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Percutaneous Posterior Tibial Nerve Stimulation for Refractory Bladder Dysfunction
Two years ago, the Division of Urology established one of the country’s first percutaneous posterior tibial nerve stimulation pathways for pediatric bladder dysfunction.

Indepenema: How Innovation in Pediatric Neurogenic Bowel Enema Delivery Can Lead to Independence
Indepenema, a tool developed at CHOP, is a handheld device that allows patients with bowel incontinence to independently administer a cone enema, improving the process.

NEBULA: A New Trans-Disciplinary Program at CHOP for Pediatric Patients with Complex Neurogenic Bladder and Bowel
Urology, General Surgery and Gastroenterology (GI) at CHOP have teamed up to provide a better approach to care for patients with pediatric bladder and bowel dysfunction.
Children’s Hospital of Philadelphia Researchers Publish First Major Study of Insights into Practice Variations Among Orthopedic Surgeons with an Expertise in Trochleoplasty
Researchers at Children’s Hospital of Philadelphia today announced results from the first ever international survey of trochleoplasty experts, which they hope will help guide current practice and future research regarding this procedure.
Children’s Hospital of Philadelphia Researchers Unveil Key Mechanism in Immune System’s Fight Against Disease
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania unlocked important new insights in how the immune system selects the right signals to alert T cells, a vital step in the prevention and treatment of serious illness. The findings were published in the journal Proceedings of the National Academy of Sciences (PNAS).
Vaccine News & Notes — January 2025
A report estimates that vaccines were directly responsible for a 40% decrease in infant deaths over the last 50 years. Find out more. You'll also learn about the rates of long COVID and about antibiotic-resistant bacteria in Ukraine.
Dr. Handy’s Corner: Can Adults Get a Booster Dose of Polio Vaccine If They’re Unsure about Their Immunity?
Watch as Dr. Handy discusses which adults might benefit from an additional dose of polio vaccine.
Feature Article: Getting Accurate Information in an Age of Misinformation
Unsure where to go to for trusted information about vaccines? Check out our list of resources. You'll also learn about why more information and access means more care when consuming that information.
Children’s Hospital of Philadelphia Researchers Develop New Tool with Potential to Advance Precision Medicine Treatment for Cancer
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania developed a new screening technology, Aptamer-based T Lymphocyte Activity Screening and SEQuencing (ATLAS-seq), to better identify antigen-reactive T cells that are more likely to offer greater immune responses against cancer cells.

Q-and-A with a Trailblazer: N. Scott Adzick, MD
In this piece, Dr. Adzick reflects on the impact the center he helped establish 30 years ago has had on the field and on families.