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Dr. Handy’s Corner: Why Are Certain Vaccines Mandated for School?
Watch as Dr. Handy discusses the history of vaccine mandates and the role they play in keeping children healthy today.
Vaccine News & Notes — October 2024
Find info about influenza deaths in children during the 2023-24 season and check out new RSV Q&A sheets.
Researchers at Children’s Hospital of Philadelphia Highlight Role of Alternative Splicing in Chemotherapy Resistance
Researchers at Children’s Hospital of Philadelphia (CHOP) have elucidated the significant role that alternative splicing – a process whereby a single gene produces multiple proteins by rearranging its messenger RNA segments in different combinations – plays in resistance to chemotherapy in relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL). The study published today in the journal Cancer Research.
Penn Medicine and Children’s Hospital of Philadelphia Create mRNA Vaccine to Prevent and Treat C. difficile
The vaccine is the first mRNA vaccine against C. difficile and would be the first vaccine in general to successfully ward off the bacterial infection.
$14M NIH grant funds gene-editing research for rare metabolic diseases at Penn and CHOP
Researchers aim to develop personalized therapies for urea cycle disorders and other genetic conditions using advanced CRISPR technology.
CHOP Cell and Gene Therapy Researcher Receives NIH New Innovator Award
Evan Weber will use this “high risk, high reward” grant to fund research into improving CAR-T therapies.

Children’s Hospital of Philadelphia’s 22nd Annual Parkway Run & Walk presented by Citadel Credit Union Raises More than $1.95 Million to Bolster Pediatric Cancer Research and Care
On a September Sunday on the Ben Franklin Parkway, nearly 8,000 supports – comprising of more than 275 teams – participated in CHOP Cancer Center’s largest fundraiser, the Parkway Run & Walk, presented by Citadel Credit Union.
Researchers at Children’s Hospital of Philadelphia Highlight Benefits of Proton Therapy for Pediatric Hodgkin Lymphoma Patients
A new study from Children’s Hospital of Philadelphia (CHOP) showed promising results for Pediatric Hodgkin Lymphoma (pHL) patients who underwent proton therapy to treat their disease in rare regions located below the diaphragm, such as the abdomen and pelvis. The study highlights the advantages of proton therapy over conventional photon radiotherapy, demonstrating fewer side effects and better protection for critical organs. It was published recently in the journal Pediatric Blood and Cancer.

Children’s Hospital of Philadelphia Successfully Separates Conjoined Twin Boys
After nearly a year at Children’s Hospital of Philadelphia (CHOP), conjoined twins Amari and Javar Ruffin were successfully separated by CHOP surgeons on August 21, 2024.
Children’s Hospital of Philadelphia Named a 2024 Leading Disability Employer by the National Organization on Disability
Children’s Hospital of Philadelphia (CHOP) is honored to announce that it has received a Leading Disability Employer Seal for 2024 from the National Organization on Disability (NOD).