Division of Neonatology Research

A biologic sample study for the validation of biomarkers of progressive necrotizing enterocolitis (NEC) and sepsis.

Children’s Hospital of Philadelphia is advancing extracorporeal life support technologies for the most critically ill children through active ECMO research.

This case study follows a 25-week infant transferred to the N/IICU at CHOP at 4 months for further management by the Newborn and Infant Chronic Lung Disease Program. The patient underwent right upper lobectomy and tracheostomy placement.

A multicenter randomized trial of laparotomy vs. drainage as the initial surgical therapy for extremely low birth weight (ELBW) infants with necrotizing enterocolitis (NEC) or isolated intestinal perforation (IP): outcomes at 18-22 months adjusted age.

A clinical trial (FFLOAT) evaluating the safety of neonatal liquid ventilation seeks to change the outlook for premature infants with severe chronic lung disease.

Research on the impact of bacterial polymerase chain reaction (PCR) and cerebrospinal fluid (CSF) cytokine levels on the diagnosis of bacterial meningitis in infants.

This case study highlights the care of an infant transferred to Children's Hospital of Philadelphia for immediate and long-term management of his necrotizing enterocolitis (NEC) that led to short bowel syndrome (SBS), one of the most devastating complications of prematurity.