ICU Clinical Pathway for Neonates at Risk for
Hypoxic-Ischemic Encephalopathy (HIE)
- Review Eligibility Criteria
- Birth history, physical examination
- Assess:
CHOP Neonatology/Transport Consult
215-590-2160
215-590-2160
- Temperature Management
- 35-35 6/7 wks: targeted normothermia
- ≥ 36 wks: therapeutic hypothermia
Neonate transported
- Team Assessment
Neonate meets criteria for HIE
Discontinue Temperature Blanket
Resume Standard Temperature Management
Resume Standard Temperature Management
Evidence
- Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants 33 to 35 Weeks’ Gestation: A Randomized Clinical Trial
- Hypothermia and Neonatal Encephalopathy
- Cooling for Newborns with Hypoxic Ischaemic Encephalopathy
- Effect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates With Hypoxic Ischemic Encephalopathy
- Effect of Depth and Duration of Cooling on Death or Disability at Age 18 Months Among Neonates With Hypoxic-Ischemic Encephalopathy
- The Frequency and Severity of MRI Abnormalities in Infants with Mild Neonatal Encephalopathy
- MRI as a Biomarker for Mild Neonatal Encephalopathy
- Treating EEG Seizures in Hypoxic Ischemic Encephalopathy: A Randomized Controlled Trial
- Adverse Neurodevelopmental Outcomes after Exposure to Phenobarbital and Levetiracetam for the Treatment of Neonatal Seizures
- View All Evidence