Background

Ana G. Cristancho, MD, PhD, is a pediatric neurologist with the Division of Neurology at Children's Hospital of Philadelphia, with special interest in fetal and neonatal neurology. Dr. Cristancho's research focus includes developing experimental models of prenatal hypoxic injury. Her goal is to understand the effect of acute and chronic low oxygen states on the developing brain throughout pregnancy to better understand new opportunities for intervention, management and prognosis.

Languages Spoken: English, Spanish

Education and Training

Medical School

MD - University of Pennsylvania School of Medicine, Philadelphia, PA

Residency

Child Neurology - Children’s Hospital of Philadelphia, Philadelphia, PA (Chief Resident)
General Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA

Fellowship

Fetal Neurology and Research Fellow - Children's Hospital of Philadelphia, Philadelphia, PA

Graduate Degree

PhD in Cancer Biology - University of Pennsylvania School of Medicine, Philadelphia, PA

Titles and Academic Titles

Attending Physician

Instructor of Neurology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2018

Mignot C, McMahon AC, Bar C, Campeau PM, … Cristancho AG, … Moller RS, Lesca G, Helbig KL, Nabbout R, Verbeek NE, Depienne C (86 authors). IQSEC2-related encephalopathy in males and females: a comparative study including 37 novel patients. Genetics in Medicine. 2018 Sep 12. [Epub ahead of print]

Gray IN, Cristancho AG, Licht DJ, Liu GT. Ocular Dipping in a Patient With Hemiplegic Migraine. Journal of Pediatric Ophthalmology and Strabismus. 2018 Jan 31;55:e4-e6.

2016

Tian G*, Cristancho AG*, Dubbs HA, Liu GT, Cowan NJ, Goldberg EM. A patient with lissencephaly, developmental delay, and infantile spasms, due to de novo heterozygous mutation of KIF2A. Molecular Genetics and Genomic Medicine. 2016 Nov; 4(6): 599–603. * co-first authors

2013

Cristancho AG, Lazar MA. Double SET point: G9a makes its mark in adipogenesis. EMBO Journal. 2013 Jan 9; 32(1): 4-6.

2011

Cristancho AG, Lazar MA. Forming functional fat: a growing understanding of adipocyte differentiation. Nature Reviews Molecular Cell Biology. 2011 Sep 28;12(11):722-34.

Cristancho AG, Schupp M, Lefterova MI, Cao S, Cohen DM, Chen CS, Steger DJ, Lazar MA. Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells. Proceedings of the National Academy of Sciences. 2011 Sep 27;108(39):16271-6.

2009

Schupp M, Cristancho AG, Lefterova MI, Hanniman EA, Briggs ER, Steger DJ, Qatanani M, Curtin JC, Schug J, Ochsner SA, McKenna NJ, Lazar MA. Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype. Journal of Biological Chemistry. 2009 Apr 3;284(14):9458-64.

Schupp M, Lefterova M, Janke J, Leitner K, Cristancho AG, Mullican SE, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh M, Albert MR, Engeli S, Gudas LJ, and Lazar MA. Retinol Saturase Promotes Adipogenesis and Is Down-Regulated in Obesity. Proceedings of the National Academy of Sciences. 2009 Jan 27;106(4):1105-10.

2008

Lefterova MI, Zhang Y, Steger DJ, Schupp M, Schug J, Cristancho A, Feng D, Zhuo D, Stoeckert, Jr CJ, Liu XS, and Lazar MA. PPARgamma and C/EBP Factors Orchestrate Adipocyte Biology Via Adjacent Binding on a Genome-Wide Scale. Genes and Development. 2008 Nov 1;22(21):2941-52.

Moise AR, Domínguez M, Alvarez S, Alvarez R, Schupp M, Cristancho AG, Kiser PD, de Lera AR, Lazar MA, Palczewski K. Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids. Journal of the American Chemical Society. 2008 Jan 30;130(4):1154-5. 

Posters and Presentations

2018

Cristancho, AG, Streicher, D, Vossough A, Treat JR, Licht DJ, Streicher, JL. Characterization of Features of PHACE Syndrome on Fetal MRI and Natural History of Postnatal Management. Presented at American Academy of Neurology. April 24, 2018.

2017

Cristancho, AG, Vossough A, Treat JR, Licht DJ, Streicher, JL. Characterization of Features of PHACE Syndrome on Fetal MRI and Natural History of Postnatal Management. Presented at American Neurological Association. October 16, 2017.

Cristancho, AG, Vossough A, Treat JR, Licht DJ, Streicher, JL. Characterization of Features of PHACE Syndrome on Fetal MRI and Natural History of Postnatal Management. Presented at International Symposium for Fetal Brain. August 24, 2017.

2015

Cristancho AG, Wedin T. Clinical Conundrums: When a fever gets cross-eyed. Society for Hospitalist Medicine Annual Meeting. March 31, 2015. (Winner of Pediatric Vignette Competition)

Cristancho AG, Foerster DL, Shinnick JE, França Jr. M, Lynch DR. Body Habitus is Inversely Related to Neurological Disease Severity in Children with Friedreich Ataxia. International Ataxia Research Conference. March 27, 2015.

Awards and Honors

  • 2018, AAN Enhanced Resident Leadership Scholarship for Child Neurology
  • 2018, Marc A. Dichter Award for Excellence in Translational Research
  • 2018, AAN Enhanced Resident Leadership Scholarship for Child Neurology
  • 2017, Jessica A. Panzer “Good Catch” award for contribution to clinical care
  • 2013, American Academy of Neurology Award for Excellence in Clinical Neurology
  • 2011, Balduin Lucke Memorial Prize for superior research on any problem in any field of experimental medicine and biology
  • 2009, FASEB NIH MARC Summer Research Conference Travel Award
  • 2004, Magna Cum Laude, General Honors, Honors in Biology, University of Miami
  • 2000-2004, Howard Hughes Medical Institute Undergraduate Research Training Program Scholar
  • 2004, Outstanding Senior in Philosophy Award
  • 2003, Howard Hughes Medical Institute Exceptional Research Opportunities Program
  • 2002, Phi Beta Kappa

Editorial and Academic Positions

Academic and Institutional Committees

2016-present, Neurocritical Care Advisory Committee

Leadership and Memberships

Memberships in Professional Organizations

2017-present, Child Neurology Society
2015-present, American Academy of Neurology