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Ana G. Cristancho, MD, PhD
Areas of expertise: Fetal neurology, Neonatal neurology
About Ana G. Cristancho, MD, PhD
Ana G. Cristancho, MD, PhD, is a pediatric neurologist with the Division of Neurology at Children's Hospital of Philadelphia, with special interest in fetal and neonatal neurology. Dr. Cristancho's research focus includes developing experimental models of prenatal hypoxic injury. Her goal is to understand the effect of acute and chronic low oxygen states on the developing brain throughout pregnancy to better understand new opportunities for intervention, management and prognosis.
Titles
Attending Physician
Instructor of Neurology, Perelman School of Medicine at the University of Pennsylvania
Awards and Honors
- 2018, AAN Enhanced Resident Leadership Scholarship for Child Neurology
- 2018, Marc A. Dichter Award for Excellence in Translational Research
- 2018, AAN Enhanced Resident Leadership Scholarship for Child Neurology
- 2017, Jessica A. Panzer “Good Catch” award for contribution to clinical care
- 2013, American Academy of Neurology Award for Excellence in Clinical Neurology
- 2011, Balduin Lucke Memorial Prize for superior research on any problem in any field of experimental medicine and biology
- 2009, FASEB NIH MARC Summer Research Conference Travel Award
- 2004, Magna Cum Laude, General Honors, Honors in Biology, University of Miami
- 2000-2004, Howard Hughes Medical Institute Undergraduate Research Training Program Scholar
- 2004, Outstanding Senior in Philosophy Award
- 2003, Howard Hughes Medical Institute Exceptional Research Opportunities Program
- 2002, Phi Beta Kappa
Leadership and Memberships
Memberships in Professional Organizations
2017-present, Child Neurology Society
2015-present, American Academy of Neurology
Editorial and Academic Positions
Academic and Institutional Committees
2016-present, Neurocritical Care Advisory Committee
Education & training
Graduate Degree
PhD in Cancer Biology - University of Pennsylvania School of Medicine, Philadelphia, PA
Medical Degree
MD - University of Pennsylvania School of Medicine, Philadelphia, PA
Residency
Child Neurology - Children’s Hospital of Philadelphia, Philadelphia, PA (Chief Resident)
General Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA
Fellowship
Fetal Neurology and Research Fellow - Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2018
Mignot C, McMahon AC, Bar C, Campeau PM, … Cristancho AG, … Moller RS, Lesca G, Helbig KL, Nabbout R, Verbeek NE, Depienne C (86 authors). IQSEC2-related encephalopathy in males and females: a comparative study including 37 novel patients. Genetics in Medicine. 2018 Sep 12. [Epub ahead of print]
Gray IN, Cristancho AG, Licht DJ, Liu GT. Ocular Dipping in a Patient With Hemiplegic Migraine. Journal of Pediatric Ophthalmology and Strabismus. 2018 Jan 31;55:e4-e6.
2016
Tian G*, Cristancho AG*, Dubbs HA, Liu GT, Cowan NJ, Goldberg EM. A patient with lissencephaly, developmental delay, and infantile spasms, due to de novo heterozygous mutation of KIF2A. Molecular Genetics and Genomic Medicine. 2016 Nov; 4(6): 599–603. * co-first authors
2013
Cristancho AG, Lazar MA. Double SET point: G9a makes its mark in adipogenesis. EMBO Journal. 2013 Jan 9; 32(1): 4-6.
2011
Cristancho AG, Lazar MA. Forming functional fat: a growing understanding of adipocyte differentiation. Nature Reviews Molecular Cell Biology. 2011 Sep 28;12(11):722-34.
Cristancho AG, Schupp M, Lefterova MI, Cao S, Cohen DM, Chen CS, Steger DJ, Lazar MA. Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells. Proceedings of the National Academy of Sciences. 2011 Sep 27;108(39):16271-6.
2009
Schupp M, Cristancho AG, Lefterova MI, Hanniman EA, Briggs ER, Steger DJ, Qatanani M, Curtin JC, Schug J, Ochsner SA, McKenna NJ, Lazar MA. Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype. Journal of Biological Chemistry. 2009 Apr 3;284(14):9458-64.
Schupp M, Lefterova M, Janke J, Leitner K, Cristancho AG, Mullican SE, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh M, Albert MR, Engeli S, Gudas LJ, and Lazar MA. Retinol Saturase Promotes Adipogenesis and Is Down-Regulated in Obesity. Proceedings of the National Academy of Sciences. 2009 Jan 27;106(4):1105-10.
2008
Lefterova MI, Zhang Y, Steger DJ, Schupp M, Schug J, Cristancho A, Feng D, Zhuo D, Stoeckert, Jr CJ, Liu XS, and Lazar MA. PPARgamma and C/EBP Factors Orchestrate Adipocyte Biology Via Adjacent Binding on a Genome-Wide Scale. Genes and Development. 2008 Nov 1;22(21):2941-52.
Moise AR, Domínguez M, Alvarez S, Alvarez R, Schupp M, Cristancho AG, Kiser PD, de Lera AR, Lazar MA, Palczewski K. Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids. Journal of the American Chemical Society. 2008 Jan 30;130(4):1154-5.