Christina Bergqvist, MD

Locations: Main Hospital; Buerger Center for Advanced Pediatric Care
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)
MD - Temple Univeristy School of Medicine, Philadelphia, PA
Pediatrics - St. Christopher's Hospital for Children/Temple University School of Medicine, Philadelphia, PA
Pediatrics - St. Christopher's Hospital for Children/Temple University School of Medicine, Philadelphia, PA
Child Neurology - The Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA
Clinical Neuro-Physiology, EEG and Epilepsy - The Children's Hospital of Philadelphia, Philadelphia, PA
Child Neurology – American Board of Psychiatry and NeurologyEpilepsy – American Board of Psychiatry and Neurology
Attending Physician
Medical Director, Dietary Treatment Program
Associate Professor of Neurology, Perelman School of Medicine at the University of Pennsylvania
Marsh ED, Bergqvist AGC, Medne L, Haasoun P, Gonatas NK, Eagle RX, Viaene A, Rorke-Adams LB : Novel Neuropathological Features of a Child with an Epileptic Encephalopathy due to presumed Polyol Dysmetabolism. Journal of Pediatric Epilepsy January 2019.
Zaman T, Helig I, Bozovic IB, DeBrosse S, Bergqvist AC, Medne L, Maver A, Helbig KL, Zang Xiahong, Goldberg EM.: "Mutations in SCN3A cause early infantile epileptic encephalopathy" Annals of Neurology 83(4): 703-717, April 2018.
Carolien G. F. de Kovel, PhD1,2; Steffen Syrbe, MD, PhD3; Eva H. Brilstra, MD, PhD1; Nienke Verbeek, MD, PhD1; Bronwyn Kerr, PhD4,5,6; Holly Dubbs, MD7; Allan Bayat, MD, PhD8; Sonal Desai, MGC, CGC9; Sakkubai Naidu, MD10,11; Siddharth Srivastava, MD12; Hande Cagaylan, MD13; Uluc Yis, MD, PhD14; Carol Saunders, PhD15,16,17; Martin Rook, PhD18; Susanna Plugge, MSc19; Hiltrud Muhle, MD20; Zaid Afawi, MD, PhD21; Karl-Martin Klein, MD, PhD22; Vijayakumar Jayaraman, MSc23; Ramakrishnan Rajagopalan, PhD23; Ethan Goldberg, MD, PhD7; Eric Marsh, MD, PhD7; Sudha Kessler, MD, MSCE7; Christina Bergqvist, MD7; Laura K. Conlin, PhD23; Bryan L. Krok, PhD23; Isabelle Thiffault, PhD15,16; Manuela Pendziwiat, MSc20; Ingo Helbig, MD7,24; Tilman Polster, MD, PhD25; Ingo Borggraefe, MD, PhD26; Johannes R. Lemke, MD, PhD27; Marie-José van den Boogaardt, MD, PhD1; Rikke S. Møller, MSc, PhD8,28; Bobby P. C. Koeleman, PhD1: "Neurodevelopmental Disorders Caused by De Novo Variants in KCNB1 Genotypes and Phenotypes" JAMA Neurol 74(10): 1228-1236, October 2017.
Masnada, Silvia; Hedrich, Ulrike BS; Gardella, Elena; Schubert, Julian; Kaiwar, Charu; Klee, Eric W; Lanpher, Brendan C; Gavrilova, Ralitza H; Synofzik, Matthis; Bast, Thomas; Gorman, Kathleen; King, Mary D; Allen, Nicholas M; Conroy, Judith; Zeev, Bruria Ben; Tzadok, Michal; Korff, Christian; Dubois, Fanny; Ramsey, Keri; Narayanan, Vinodh; Serratosa, Jose M; Giraldez, Beatriz G; Helbig, Ingo; Marsh, Eric; O'Brian Margaret; Bergqvist, Christina A; Binelli, Adrian; Porter, Brenda; Caglayan, Hande S; Arslan, Muluay; Pena, Sergio D.J; Sisodiya, Sanjay M; Balestrini, Simona; Syrbe, Steffen; Veggiotti, Pierangelo; Lemke, Johannes R; Moller, Rikke S; Lerche, Holger and Guido Rubboli: "Clinical spectrum and genotype-phenotype associations of KCNA2-related encephalopathies" Brain. Oxford University Press, 140(9): 2337-2354, September 2017.
Groveman S, Fenton C, Randall R, Chee C, Bergqvist AGC : "Improved lipid profile with ketocal® 4:1 liquid" Infant Child & Adolescent Nutrition 7(3): 157-161, June 2015.
Fenton C, Groveman S, Chee C, AGC Bergqvist : "Use of Expressed Breast Milk with the Ketogenic Diet" Infant, Child & Adolescent Nutrition 7(6): 342-346, June 2015.
Groleau V,Schall J, Stallings V, Bergqvist AGC : "Long Term Impact of Ketogenic Diet on Growth and Resting Energy Expenditure in Children with Intractable Epilepsy" Developmental Medicine & Child Neurology 56(9): 898-904, September 2014 Notes: doi: 10.1111/dmcn.12462. [Epub ahead of print).
Li H, Jauregui J ,Fenton C, Chee C, Bergqvist AGC: "Epilepsy Treatment Simplified through Mobile Ketogenic Diet Planning" Journal of Medical Application 3(2): 11-15, July 2014.
Taub K, Kilaru-Kessler S, Bergqvist AGC: "Risk of Seizure Recurrence After Achieving Initial Seizure Freedom on the Ketogenic Diet" Epilepsia 55(4): 579-83, April 2014 Notes: published ahead on line doi: 10.1111/epi.12583. Epub 2014 Mar 27.
Kilaru Kessler S, Gallagher PG, Shellhaas RA, Clancy RR, Bergqvist AGC: "Early EEG improvement after ketogenic diet initiation" Epilepsy Research. Elsevier, 94((1-2)): 94-101, March 2011 Notes: Accepted Jan 2011, online Feb 2011.
Fenton,C., Chee, C.M., Bergqvist, A.G.C: "Manipulation of types of fats and cholesterol intake can successfully improve the lipid profile while maintaining the efficacy of the ketogenic diet" Infant, Child and Adolescent Nutrition 1(6): 338-341, December 2009 Notes: Accepted for publication October 12, 2009.
Bergqvist AGC, Schall JI, Stallings VA, Zemel BS: "Progressive bone mineral content loss in children with intractable epilepsy treated with the ketogenic diet." American Journal of Clinical Nutrition 88: 1678-84, December 2008 Notes: Accepted for publication August 30, 2008.
Bergqvist AGC, Schall JI, Trabulsi J, Stallings VA: "Growth failure in children with intractable epilepsy is not due to increased resting energy expenditure." Developmental Medicine & Child Neurology 50: 439-444, April 2008.
Caspari SS, Bergqvist AGC, Kotegal S, Strand EA. : "Obstructive sleep apnea, seizures, and childhood apraxia of speech." Pediatric Neurology 38: 422-425, March 2008.
Kilaru S, Bergqvist AGC: "Current treatment of Myoclonic Astatic Epilepsy: Clinical experience at the Children's Hospital of Philadelphia." Epilepsia 48(9): 1-5, September 2007.
Bergqvist AGC, Schall JI, Richard EL, Gallagher PR, Stallings VA: "Predictive power of first morning glucose and the ketogenic diet." Neuropediatrics 38: 193-196, September 2007.
Volpe S, Schall JI, Gallagher MA, Stallings VA, Bergqvist AGC: "Nutrient intake of children with intractable epilepsy compared with healthy children." Journal of the American Dietetic Association. Journal of the American Dietetic Association, 107(6): 1014-1018, June 2007.
Kossoff EH, Pyzik PL, Rubenstein JE, Bergqvist AGC, Buchhalter JR, Donner EJ, Nordli DR, Wheless JR: "Combined ketogenic diet and vagus nerve stimulation: Rational polytherapy?" Epilepsia 48(1): 77-81, January 2007.
Bergqvist AGC, Schall JI, Stallings VA: "Vitamin D status in children with intractable epilepsy, and impact of the ketogenic diet." Epilepsia 48(1): 66-71, January 2007.
Bergqvist AGC, Schall JI, Gallagher PR, Cnaan A, and Stallings VA: "Fasting versus gradual initiation of the ketogenic diet: A prospective randomized, clinical trial of efficacy." Epilepsia 46(11): 1810-1819, November 2005.
Farina L, Bergqvist AGC, Zimmerman RA, Haselgrove J, Hunter JV, Bilaniuk LT: "Acute diffusion abnormalities in the hippocampus of children with new-onset of seizures; The development of mesial temporal sclerosis." Neuroradiology 46(4): 251-257, April 2004.
Wang ZJ, Bergqvist AGC, Hunter JV, Jin D, Wang DJ, Wehrli S, Zimmerman RA: "In vivo measurement of brain metabolites using two-dimensional double-quantum MR Spectroscopy-exploration of GABA levels in a ketogenic diet." Magnetic Resonance in Medicine 49(4): 615-619, April 2003.
Bergqvist AGC. : "Side Effects of Epilepsy." Epilepsy Quarterly 6(1): 4,11-12, Spring 1998.
J.N. Brenton, B. Banwell, A.G.C. Bergqvist, D. Lehner-Gulotta, E. Leytham, M. Goldman : Application of a Modified Ketogenic Diet in Relapsing-Remitting Multiple Sclerosis: A Pilot Study European Committee for Treatment and Research in Multiple Sclerosis Berlin, Germany. ECTRIM, October 10-12 2018.
Groveman S, Fenton C, Chee C, Vondran P, Walker M, Tefft T, Grimberg A, Bergqvist AGC: The use of growth hormone in children on the ketogenic diet; A case series. The 6th Global Symposium on Ketogenic Therapies for Neurological Disorders, Jeju Korea October 2018.
Translated by McDowell P, Rodriguez M: Ketogenic Diet Manual, Fifth Edition, translated in Spanish. CHOP KD program. CHOP, July 2017.
Bergqvist AGC, Bulgun CA, Tuttle A, Mulliken L, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchanges System, Third Edition. CHOP Division of Neurology January 2009.
Bergqvist AGC, Bulgun CA, Tuttle A, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchange System, Second Edition. CHOP Division of Neurology December 2006.
Bergqvist AGC, Bettler J, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchange System, Version 1.5. CHOP Division of Neurology July 2004.
Bergqvist AGC, Bettler J, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchange System, First Edition. CHOP Division of Neurology December 2001.
Bergqvist, AGC, MD; Fenton, C, RD, CSP, LDN; Groveman, S, MS, RD, LDN; Tefft, S, RN, Conteh, H, BS, Sheen, J, BS, Vondran, P, BS; Chee, C, RN.: "Ketogenic Diet Manual, Fifth Edition" CHOP. CHOP, Dietary Treatment Program of Epilepsy and Neurological Disorders Page: 1-85, February 2017 Notes: Education material for families in our program.
Dlugos D,Bergqvist AGC, Clancy R, Nordli D : "Pediatric and neonatal electroencephalography" Current Practice in Clinical Electroencephalography 4th Edition. Ebersole, Nordli and Husain (eds.). Lippincott Williams & Wilkins, Page: 125-213, June 2014.
Bergqvist, Christina, MD; Fenton, Cagla, RD, LDN;Tuttle, Alan MSW,LCSM; Mullikin, Lisa, MSS,LSW; Chee, Claire, RN: Ketogenic Diet Manual, Fourth Edition. The Children's Hospital of Philadelphia. CHOP, Page: 1-76, April 2013.
Bergqvist, AGC: "Dietary therapies and bone health" Dietary treatment of epilepsy: Practical implementation of ketogenic therapy. Neal, E (eds.). Wiley-Blackwell, Page: 159-166, 2012.
Bergqvist, AGC: Dietary therapies and bone health Dietary treatment of epilepsy. Neal, E (eds.). Wiley-Blackwell, 2011.
Bergqvist AGC: "Encephalitis" In: The 5-minute Pediatric Consult, Fifth Edition. Schwartz MW (eds.). Williams & Wilkins, Page: 296-297, 2008.
Bergqvist AGC: "Myoclonic-Astatic Epilepsy or Doose Syndrome". Pediatric Epilepsy Case Studies: From Infancy and Childhood through Adolescence Chapman K, and Rho J (eds.). CRC Press, Page: 231-39, September 2008 Notes: First Edition.
Bergqvist AGC: "Tics" In: The 5-minute Pediatric Consult, Fourth Edition. Schwartz MW (eds.). Williams & Wilkins, Page: 844-845, 2005.
Bergqvist AGC: "Encephalitis" In: The 5-minute Pediatric Consult, Fourth Edition. Schwartz MW (eds.). Williams & Wilkins, Page: 352-353, 2005.
Bergqvist AGC: "Indications and Contraindications of the Ketogenic Diet." In: Epilepsy and the Ketogenic Diet. Stafstrom, CE, and Rho JM (eds.). Humana Press, Inc. Page: 111-121, 2004.
Clancy RR, Bergqvist AGC, Dlugos D: "Neonatal Electro Encephalography" In: Current Practice of Clinical Electroencephalography, Third Edition. Ebersole JS, and Pedley TA (eds.). Lippincott Williams & Wilkins, Page: 160-234, 2003.
Bergqvist AGC, Clancy RR: "Infarctions and Stroke in the Fetus and Neonates and Neonatal Seizures." In: Fetal and Neonatal Secrets. Hanley & Belfus (eds.). 2003.
Bergqvist AGC: "Encephalitis" In: The 5-minute Pediatric Consult, Third Edition. Schwartz MW (eds.). Williams & Wilkins, Page: 344-345, 2003.
Bergqvist AGC: "Tics" In: The 5-minute Pediatric Consult, Third Edition. Schwartz MW (eds.). Williams & Wilkins, Page: 822-823, 2003.
Bergqvist AGC: "Encephalitis" In: The 5-minute Pediatric Consult, Second Edition Schwartz MW (eds.). William & Wilkins Page: 344-345, 2000.
Bergqvist AGC: "Tics" In: The 5-minute Pediatric Consult, Second Edition. Schwartz MW (eds.). William & Wilkins Page: 814-815, 2000.
Lynch D, Bergqvist AGC: "Acute Ataxia" In: Gellis & Kagan's Current Pediatric Therapy 16. Burg FD (eds.). WB Saunders, Page: 447-449, 1998.
Bergqvist AGC, Lynch DR: "Movement Disorders" In: Gellis & Kagan's Current Pediatric Therapy 16. Burg FD (eds.). WB Saunders, Page: 455-459, 1998.
Bergqvist AGC, Lynch D: "Pediatric Movement Disorders" Gellis & Kagan's Current Pediatric Therapy 16. Burg. WB Saunders (eds.). Page: 455-459, 1998.
Bergqvist AGC: "Tics (movement disorder)" In: The 5-minute Pediatric Consult Schwartz MW (eds.). William & Wilkins, Page: 60-61, 1997.
Bergqvist AGC: "Encephalitis" In: The 5-minute Pediatric Consult Schwartz MW (eds.). William & Wilkins, Page: 308-309, 1997.
Bergqvist AGC, Bulgun CA, Tuttle A, Mulliken L, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchanges System, Third Edition. CHOP Division of Neurology January 2009.
Bergqvist AGC, Bulgun CA, Tuttle A, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchange System, Second Edition. CHOP Division of Neurology December 2006.
Bergqvist AGC, Bettler J, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchange System, Version 1.5. CHOP Division of Neurology July 2004.
Bergqvist AGC, Bettler J, Chee CM: The Children's Hospital of Philadelphia Ketogenic Diet Manual and Exchange System, First Edition. CHOP Division of Neurology December 2001.
Bergqvist AGC. "Dravet Syndrome and use of ketogenic diet(s)" 6th Global symposium on ketogenic therapies for neurological disorders, Jeju, Korea. Oct 2018.
Bergqvist AGC. "2018-Ketogenic diet(s)", "How do we approach Treatment Resistant Infantile Spasms" and " Management of the Ketogenic diet(s)" South American League Against Epilepsy, San Paulo, Brazil. Jun 2018.
Bergqvist AGC. "Ketogenic diet therapies", Stromstad Academy, Stromstad Sweden. Jun 2018.
Bergqvist AGC. "When standard treatments fail" infantile spasms, Pediatric State of the Art Symposium, American Epilepsy Society, Washington DC. Dec 2017.
Bergqvist AGC. "Dietary therapies for Dravet Syndrome", Dravet Syndrome Foundation Northeast Chapter, Langhorne, PA. Oct 2017.
Bergqvist AGC. "Dietary Therapies State of the Art 2017" and "Clinical considerations, patient cases" Nordic Keto meeting, Queen Silvia's Children's Hospital, Gothenburg, Sweden. Sep 2017.
Bergqvist AGC. "Clinical management of Epilepsy; News and Future Developments" Danone (Nutricia), Utrecht, Netherlands. Jul 2017.
Bergqvist AGC. "Epilepsy and ketogenic diet; current clinical challenges in patient management" Danone (Nutricia), Utrecht, Netherlands. Jul 2017.
Bergqvist AGC. "Side Effects of Ketogenic Diet(s)", Keto University- Nutricia, Chicago, Ill. Jun 2017.
2007-present, Ad Hoc Reviewer /Developmental Medicine & Child Neurology
2007-present, Ad Hoc Reviewer/Pediatrics
2007-present, Ad Hoc Reviewer/Neurology
2007-present, Ad Hoc Reviewer/Epilepsy Research
2006-present, Ad Hoc Reviewer/Journal of Pediatrics
2006-present, Ad Hoc Reviewer/Neuropediatrics
2002-present, Ad Hoc Reviewer/Annals of Neurology
2001-present, Ad Hoc Reviewer/Neurology
2000-present, Ad Hoc Reviewer/Epilepsia
2005-present, Rounding Committee
2004-present, General Clinical Research Centers Advisory Committee/CTRC
2000-present, Neurology Residency Selection Committee