Máire Abraham Conrad, MD, MS
Areas of expertise: Inflammatory bowel disease (IBD), Very early onset inflammatory bowel disease
Locations: Main Building, Buerger Center for Advanced Pediatric Care
About Máire Abraham Conrad, MD, MS
Titles
Gastroenterologist
Assistant Professor of Pediatrics (Gastroenterology, Hepatology and Nutrition), Perelman School of Medicine at the University of Pennsylvania
Certifications
Pediatric Gastroenterology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics
Awards and Honors
2022, North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Young Clinical Investigator Award
2020, Pediatric Residency Early Career Faculty Honor Roll, Children's Hospital of Philadelphia
2016, Komorav Competition Gastroenterology Fellow Research Award - 2nd Place
2016-2019, Entrepreneurial Science Scholar, Children's Hospital of Philadelphia
2016, American Gastroenterological Association Early Stage Investigator Award
2015, Salix Pharmaceuticals Fellowship2Leadership GI Fellows' Travel Grant
2010, Alpha Omega Alpha Honor Medical Society, Drexel University College of Medicine
Leadership and Memberships
Memberships in Professional Organizations
2013-present, North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition
- 2021-present, IBD committee
- 2019-present, Fecal Microbiota Transplant Special Interest Group
2013-present, American Gastroenterological Association
2013-present, Crohn’s & Colitis Foundation of America
Editorial and Academic Positions
Editorial Positions
Peer Review
2021-present, Pediatric Research
2021-present, Crohn's Colitis 360
2021-present, Scientific Reports
2020-present, BMJ Open Gastroenterology
2019-present, European Journal of Pediatrics
Academic and Institutional Committees
2019-present, GI Scientific Review Committee, Chair
Research Interests
Inflammatory bowel disease
Very early onset inflammatory bowel disease
Microbiome
Education & training
Graduate Degree
MS in Human Nutrition - Columbia University College of Physicians and Surgeons, New York, NY
Medical Degree
MD - Drexel University College of Medicine, Philadelphia, PA
Residency
Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA
Fellowship
Pediatric Gastroenterology - The Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2023
Lemons JMS*, Conrad MA*, Tanes C, Chen J, Friedman ES, Roggiani M, Curry D, Chau L, Hecht AL, Harling L, Vales J, Kacherlies KE, Baldassano RN, Goulian M, Bittinger K, Master SR, Lu L, Wu GD: Enterobacteriaceae growth promotion by intestinal acylcarnitines, a biomarker of dysbiosis in Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology 17: 131-148, September 2023.
Gonzalez I, Conrad MA, Weinbrom S, Patel T, Kelsen JR, Russo P,: Clinicopathologic Characterization of Lymphocytic Colitis in the Pediatric Population. Pediatric and Developmental Pathology 2023 Notes: In press.
2022
20. Rudra S, Shaul E, Conrad M, Patel T, Moore A, Dawany N, Canavan MC, Sullivan KE, Behrens E, Kelsen J.: Ruxolitinib: Targeted Approach for Treatment of Autoinflammatory Very Early Onset Inflammatory Bowel Disease. Clinical Gastroenterology and Hepatology 20(6): 1408-10, June 2022.
Kelsen J, Dawany N, Conrad M, Patel T, Devoto M, Maurer K, Sullivan KE. : Clinical and laboratory predictors of monogenic very early onset inflammatory bowel disease. Clin Immunol. Jul 2022.
Shaul E, Conrad MA, Dawany N, Patel T, Canavan MC, Baccarella A, Weinbrom S, Aleynick D, Sullivan KE, Kelsen JR.: Canakinumab for the treatment of autoinflammatory very early onset- inflammatory bowel disease. Front Immunol 13, September 2022.
2021
Judith R Kelsen 1, Noor Dawany 2, Maire A Conrad 1, Tatiana A Karakasheva 1, Kelly Maurer 3, Jane M Wei 1, Selen Uman 4, Maiah H Dent 1, Rithika Behera 1, Laura M Bryant 1, Xianghui Ma 1, Leticia Moreira 5, Priya Chatterji 6, Rawan Shraim 1, Audrey Merz 1, Rei Mizuno 7, Lauren A Simon 1, Amanda B Muir 1, Claudio Giraudo 8, Edward M Behrens 9, Kelly A Whelan 10, Marcella Devoto 11 12, Pierre A Russo 13, Sarah F Andres 14, Kathleen E Sullivan 3, Kathryn E Hamilton 1: Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes. Inflammatory Bowel Diseases 27(2): 256-67, January 2021.
Patel T, Henrickson SE, Moser EK, Field NS, Maurer K, Dawany N, Conrad M, Bunin N, Freedman JL, Heimall J, Arnold DE, Wang J, Markowitz JE, Payne-Poff SB, Williams KW, Russo PA, Wherry EJ, Devoto M, Oliver P, Sullivan KE, Kelsen JR: Immune dysregulation in human ITCH deficiency successfully treated with hematopoietic cell transplantation. J Allergy Clin Immunol Pract 9(7): 2885-2893, Jul 2021.
Holbein C, Plevinsky J, Patel T, Conrad M, Kelsen JR.: Pediatric Global Health and Gastrointestinal Symptoms in Children with Very Early-Onset Inflammatory Bowel Disease. Journal of Pediatric Psychology 46(7): 747-756, Aug 2021.
Nicholson MR, Hourigan SK, Conrad M, Goyal A, Jensen K, Kelsen J, Kennedy M, Weatherly M, Kahn SA.: Current Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children. Am J Gastroenterol 116(9): 1954-1956, Sep 2021.
Dou Y, Maurer K, Conrad M, Patel T, Shraim R, Sullivan KE, Kelsen J: Mucosal Invariant T cells are Diminished in Very Early-Onset Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr 73(4): 529-536, Oct 2021.
Conrad MA, Kelsen JR: Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease: A Clinician's Dilemma. Journal of Pediatric Infectious Diseases Society 17(10(Supplement 3)): S41-S45, Nov 2021.
2020
Kelsen JR, Conrad MA, Dawany N, Patel T, Shraim R, Merz A, Maurer K, Sullivan KE, Devoto M: The Unique Disease Course of Children with Very Early Onset Inflammatory Bowel Disease. Inflammatory Bowel Diseases 26(6): 909-18, May 2020.
Bushman FD, Conrad M, Ren Y, Zhao C, Gu C, Petucci C, Kim MS, Abbas A, Downes KJ, Devas N, Mattei LM, Breton J, Kelsen J, Marakos S, Galgano A, Kachelries K, Erlichman J, Hart JL, Moraskie M, Kim D, Zhang H, Hofstaedter CE, Wu GD, Lewis JD, Zackular JP, Li H, Bittinger K, Baldassano R.: Multi-omic Analysis of the Interaction between Clostridioides difficile Infection and Pediatric Inflammatory Bowel Disease. Cell Host Microbe 28(3): 422-433, Sept 2020.
Liang G*, Conrad MA*, Kelsen JR, Kessler LR, Breton J, Albenberg LG, Marakos S, Galgano A, Devas N, Erlichman J, Zhang H, Mattei L, Bittinger K, Baldassano RN, Bushman FD. *Co-First Author: The dynamics of the stool virome in very early onset inflammatory bowel disease. J Crohns Colitis. 14(11): 1600-1610, November 2020.
2019
Conrad MA, Carreon CK, Dawany N, Russo P, Kelsen JR.: Distinct histopathological features at diagnosis of very early onset inflammatory bowel disease. J Crohns Colitis 13(5): 615-625, April 2019.
2017
Rosenbaum DG, Conrad MA, Biko DM, Ruchelli ED, Kelsen JR, Anupindi SA: Ultrasound and MRI predictors of surgical bowel resection in pediatric Crohn disease. Pediatric radiology 47(1): 55-64, Jan 2017.
Raina A, Conrad MA, Sahn B, Sedarat A, Ginsberg GG, Ahmad NA, Chandrasekhara V, Mamula P, Kochman ML: Endoscopic ultrasound with or without fine-needle aspiration has a meaningful impact on clinical care in the pediatric population. Endoscopic ultrasound 6(3): 195-200, May-Jun 2017.
Conrad MA, Dawany N, Sullivan KE, Devoto M, Kelsen JR: Novel ZBTB24 mutation associated with immunodeficiency, centromere instability, and facial anomalies type 2 syndrome identified in a patient with very early onset inflammatory bowel disease. Inflammatory Bowel Diseases 23(12): 2252-2255, Dec 2017.
2016
Conrad MA, Cui Ji, Lin HC: Sertraline-Associated Cholestasis and Ductopenia Consistent with Vanishing Bile Duct Syndrome. The Journal of pediatrics 169(1): 313-5.e1, Feb 2016.
Conrad MA, Stein RE, Maxwell EC, Albenberg L, Baldassano RN, Dawany N, Grossman AB, Mamula P, Piccoli DA, Kelsen JR: Vedolizumab Therapy in Severe Pediatric Inflammatory Bowel Disease. Inflammatory bowel diseases 22(10): 2425-31, Oct 2016.
2013
Enestvedt BK, Tofani C, Lee DY, Abraham M, Shah P, Chandrasekhara V, Ginsberg GG, Long W, Ahmad N, Jaffe DL, Mamula P, Kochman ML: Endoscopic retrograde cholangiopancreatography in the pediatric population is safe and efficacious. Journal of Pediatric Gastroenterology & Nutrition 57(5): 649-54, Nov 2013.
2007
Katz LEL, Jawad AF, Ganesh J, Abraham M, Murphy K, Lipman TH : Fasting c-peptide and insulin-like growth factor-binding protein-1 levels help to distinguish childhood type 1 and type 2 diabetes at diagnosis Pediatric Diabetes 8(2): 53-59, Apr 2007.
2006
Katz LEL, Abraham M, Johansen L, Jawad A : Leptin levels decline steadily during prolonged fasting in lean children. Journal of Pediatrics 149(6): 798-802, Dec 2006.
2005
Katz LEL, Swami S, Abraham M, Murphy KM, Jawad AF, McKnight-Menci H, Berkowitz R: Neuropsychiatric disorders at the presentation of type 2 diabetes mellitus in children. Pediatric Diabetes 6(2): 84-89, Jun 2005.
Abstracts (includes Posters and Scientific Presentations)
2023
Bacarella A, Pickering O, Patel T, Boyer B, Dawany N, Heimall J, Bunin N, Sullivan KE, Conrad MA, Kelsen JR: Single center Retrospective Analysis of Hematopoietic Stem Cell Transplant in Patients with Monogenic Inflammatory Bowel Disease. Gastroenterology 2022 Notes: Oral presentation given at Digestive Disease Week 2023.
Nema, N, Dawany N, Constant B, Albenberg L, Stein R, Mitchel E, Patel T, Boyer B, Grossman A, Baldassano R, Kelsen J, Conrad M: Upadacitinib for the treatment of refractory pediatric inflammatory bowel disease. Gastroenterology 2023 Notes: oral presentation at Digestive Disease Week 2023.
2020
Breton J Tu V, Tanes C, Quinn R, Conrad M, Kachelries K, Bittinger K, Baldassano R, Compher C, Albenberg L: Dietary Inflammatory Potential and Food Patterns in Relation to Gut Microbiome Among Children with Crohn's Disease: A Comparative Study with Healthy Controls North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Annual Meeting, Chicago, IL Nov 2020 Notes: poster.
Lectures by Invitation
2023
Very Early Onset Inflammatory Bowel Disease, NASPGHAN visits LASPGHAN International Webinar Series. Apr 2023.
2022
Conrad M. "Multicenter, Real-World Experience with Fidaxomicin for the Treatment of Pediatric C. difficile Infection", Oral Presentation, North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting 2022, Orlando FL. Oct 2022.
Conrad M. Very Early Onset Inflammatory Bowel Disease: A Multidisciplinary Approach, LeBonheur Children's Hospital, Memphis TN, virtual. Apr 2022.
2021
Conrad M. "Very Early Onset Inflammatory Bowel Disease" Stony Brook Children's Hospital, Stony Brook, NY. Oct 2021.
Conrad M. "Very Early Onset Inflammatory Bowel Disease" University of Miami School of Medicine Division of Pediatric GI, Miami, FL - Clinical Conference virtual presentation. June 2021.
Conrad M. Clostridioides difficile and fecal microbiota transplant in children, Golisano Children's Hospital, Pediatric GI Conference, Rochester, NY via Zoom. Mar 2021.
2019
Conrad M. Very Early Onset Inflammatory Bowel Disease, St Peters University Hospital Resident Noon Conference, New Brunswick, NJ. Oct 2019.
Conrad M. Updates in Pediatric Inflammatory Bowel Disease, St. Peters University Hospital Visiting Professor Grand Rounds, New Brunswick, NJ. Oct 2019.
Conrad M. The Intestinal Microbiome of Inflammatory Bowel Disease across the Pediatric Age Range, Crohn's and Colitis Congress, Las Vegas, NV. Feb 2019.
Books
Conrad MA, Wu G, Kelsen JR: Chapter 4: The Gut Microbiota and Inflammatory Bowel Disease. Pediatric Inflammatory Bowel Disease. Springer, 4: 49-59, 2023.
Conrad M, Miller L, Chan V.: Writing the Business Plan for a Life Science Startup. Academic Entrepreneurship for Medical and Health Scientists. Gooneratne, N., McGarrigle, R., and Winston, F (eds.). October 2019 Notes: https://repository.upenn.edu/ace/
Conrad M, Wu G, Kelsen JR: The Gut Microbiota and Inflammatory Bowel Disease. Pediatric Inflammatory Bowel Diseases. Mamula P, Grossman AB, Baldassano R, Kelsen JR, Markowitz (eds.). Springer, 3: 45-54, 2017.
Editorials, Reviews, Chapters
2020
Conrad MA, Hoffman NJF, Maxwell EC, Picoraro JA: Gastroenterology. Pediatric Secrets, 7th edition. Polin R, Ditmar M (eds.). Elsevier, September 2020.
2018
Conrad MA, Maxwell EC: Intestinal Disorders. Nelsons Pediatrics Board Review. Elsevier, Page: 187-200, 2018.
2016
Liacouras C, Wendel D, Jump C, Conrad M, Hoffman N, Maxwell E, Muir A, Waisbourd-Zinman O. Gastroenterology in Polin and Ditmar (2016) Pediatric Secrets, 6th Edition, Philadelphia, PA: Elsevier.