Benjamin L. Laskin, MD, MS

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Benjamin L. Laskin, MD, MS, is an attending physician in the Division of Nephrology, the Kidney Transplant and Dialysis Program, and the Cancer Survivorship Program at CHOP.

Locations: Main Hospital

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

Benjamin Laskin, MD, is an attending physician at Children's Hospital of Philadelphia and an Assistant Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania. 

Dr. Laskin completed his undergraduate at Duke University where he graduated magna cum laude with a major in Economics and minors in Chemistry and History. He attended the University of Maryland School of Medicine where he graduated summa cum laude and received the Faculty Medal of Honor and was the commencement speaker. He completed his pediatrics residency and fellowship in pediatric nephrology at Cincinnati Children’s Hospital Medical Center. As a fellow, Dr. Laskin was awarded the Fellowship Scholarly Research Award.

Following his fellowship, he joined the faculty at Children's Hospital of Philadelphia. Dr. Laskin’s research interests are in infections and kidney disease in immunosuppressed children, including those receiving a bone marrow or solid organ transplant. He is the recipient of a K23 Career Development Award from the National Institutes of Health and a New Investigator Award from the American Society for Blood and Marrow Transplantation. Dr. Laskin has published over 60 manuscripts and several book chapters. He serves as the Clinical Operations Director for the Division of Nephrology, an EPIC electronic health record clinical champion, and the Medical Director for Quality Improvement for the Transplant Center at Children's Hospital of Philadelphia.

Education and Training

Medical School

MD - University of Maryland School of Medicine, Baltimore, MD

Residency

Pediatrics - Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Fellowship

Pediatric Nephrology - Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Board Certification

Pediatric Nephrology
Pediatrics

Graduate Degree

MS in Clinical and Translational Research - University of Cincinnati, Cincinnati, OH

Titles and Academic Titles

Attending Physician

Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Research Interests

Improving outcomes for dialysis and transplant patients
Kidney injury following bone marrow transplant
Comparative effectiveness/cost-effectiveness

Publications

Papers

2019

Gustafson MA, McCormick EM, Perera L, Longley MJ, Bai R, Kong J, Dulik M, Shen L, Goldstein AC, McCormack SE, Laskin BL, Leroy BP, Ortiz-Gonzalez XR, Ellington MG, Copeland WC, Falk MJ. Gustafson MA, McCormick EM, Perera L, Longley MJ, Bai R, Kong J, Dulik M, Shen L, Goldstein AC, McCormack SE, Laskin BL, Leroy BP, Ortiz-Gonzalez XR, Ellington MG, Copeland WC, Falk MJ. PLoS One. 2019 Sep 3;14(9):e0221829. doi: 10.1371/journal.pone.0221829. eCollection 2019. PMID: 31479473

Weiss Scott L, Balamuth Fran, Thurm Cary W, Downes Kevin J, Fitzgerald Julie C, Laskin Benjamin L. Major Adverse Kidney Events in Pediatric Sepsis. Clinical journal of the American Society of Nephrology : CJASN 14(5): 664-672, May 2019.

Schuh Meredith P, Bennett Michael R, Lane Adam, Jodele Sonata, Laskin Benjamin L, Devarajan Prasad. Haptoglobin degradation product as a novel serum biomarker for hematopoietic stem cell transplant-associated thrombotic microangiopathy.. Pediatric nephrology (Berlin, Germany) 34(5): 865-871, May 2019.

Warady Bradley A, Iles Janet N, Ariceta Gema, Dehmel Bastian, Hidalgo Guillermo, Jiang Xun, Laskin Benjamin, Shahinfar Shahnaz, Vande Walle Johan, Schaefer Franz. A randomized, double-blind, placebo-controlled study to assess the efficacy and safety of cinacalcet in pediatric patients with chronic kidney disease and secondary hyperparathyroidism receiving dialysis. Pediatric nephrology (Berlin, Germany) 34(3): 475-486, Mar 2019.

2018

Foster BJ, Mitsnefes MM, Dahhou M, Zhang X, Laskin BL. Changes in Excess Mortality from End Stage Renal Disease in the United States from 1995 to 2013. Clin J Am Soc Nephrol. 2018 Jan 6;13(1):91-99.

2017

Laskin BL, Huang G, King E, Geary DF, Licht C, Metlay JP, Furth SL, Kimball T, Mitsnefes M. Short, frequent, 5-days-per-week, in-center hemodialysis versus 3-days-per week treatment: a randomized crossover pilot trial through the Midwest Pediatric Nephrology Consortium. Pediatr Nephrol. 2017 Aug;32(8):1423-1432.

Kakajiwala A, Jemielita T, Hughes JZ, Windt K, Denburg M, Goldstein SL, Laskin B. Membrane pressures predict clotting of pediatric continuous renal replacement therapy circuits. Pediatr Nephrol. 2017 Jul;32(7):1251-1261.

Laskin BL, Jiao J, Baluarte HJ, Amaral S, Furth SL, Akimova T, Hancock WW, Levine MH, Reese PP, Beier UH. The Effects of Tacrolimus on T-Cell Proliferation Are Short-Lived: A Pilot Analysis of Immune Function Testing. Transplant Direct. 2017 Jul 19;3(8):e199.

2016

Laskin BL, Singh HK, Beier UH, Moatz T, Furth SL, Bunin N, Witte D, Goebel J, Davies SM, Dandoy C, Jodele S, Nickeleit V. The Noninvasive Urinary Polyomavirus Haufen Test Predicts BK Virus Nephropathy in Children After Hematopoietic Cell Transplantation: A Pilot Study. Transplantation. 2016 Oct;100(10):e81-7.

Malone K, Clark S, Palmer JA, Lopez S, Pradhan M, Furth S, Kim J, Fisher B, Laskin B. A quality improvement initiative to increase pneumococcal vaccination coverage among children after kidney transplant. Pediatr Transplant. 2016 Sep;20(6):783-9.

Jodele S, Dandoy CE, Myers KC, El-Bietar J, Nelson A, Wallace G, Laskin BL. New approaches in the diagnosis, pathophysiology, and treatment of pediatric hematopoietic stem cell transplantation-associated thrombotic microangiopathy. Transfus Apher Sci. 2016 Apr;54(2):181-90.

Jodele Sonata, Zhang Kejian, Zou Fanggeng, Laskin Benjamin, Dandoy Christopher E, Myers Kasiani C, Lane Adam, Meller Jaroslav, Medvedovic Mario, Chen Jenny, Davies Stella M: The genetic fingerprint of susceptibility for transplant associated thrombotic microangiopathy. Blood 127(8): 989-96, Feb 2016.

2015

Ruebner Rebecca L, Moatz Taylor, Amaral Sandra, Reese Peter P, Blumberg Emily A, Smith Jodi M, Danziger-Isakov Lara, Laskin Benjamin L: Outcomes among children who received a kidney transplant in the United States from a hepatitis B core antibody-positive donor, 1995-2010. Journal of the Pediatric Infectious Diseases Society Oct 2015.

Jodele Sonata, Fukuda Tsuyoshi, Mizuno Kana, Vinks Alexander A, Laskin Benjamin L, Goebel Jens, Dixon Bradley P, Chima Ranjit S, Hirsch Russel, Teusink Ashley, Lazear Danielle, Lane Adam, Myers Kasiani C, Dandoy Christopher E, Davies Stella M: Variable eculizumab clearance requires pharmacodynamic monitoring to optimize therapy for thrombotic microangiopathy after hematopoietic stem cell transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Oct 2015.

Laskin Benjamin L, Sullivan Kathleen E, Hester Jeff, Goebel Jens, Davies Stella M, Jodele Sonata: Antibodies to BK virus in children prior to allogeneic hematopoietic cell transplant. Pediatric blood & cancer 62(9): 1670-3, Sep 2015.

Wallace Gregory, Jodele Sonata, Howell Jonathan, Myers Kasiani C, Teusink Ashley, Zhao Xueheng, Setchell Kenneth, Holtzapfel Catherine, Lane Adam, Taggart Cynthia, Laskin Benjamin L, Davies Stella M: Vitamin D deficiency and survival in children after hematopoietic stem cell transplant. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 21(9): 1627-31, Jun 2015.

2014

Laskin Benjamin L, Nehus Edward, Goebel Jens, Furth Susan, Davies Stella M, Jodele Sonata: Estimated versus measured glomerular filtration rate in children before hematopoietic cell transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20(12): 2056-61, Dec 2014.

Laskin Benjamin L, Mitsnefes Mark M, Dahhou Mourad, Zhang Xun, Foster Bethany J: The mortality risk with graft function has decreased among children receiving a first kidney transplant in the United States. Kidney international 87(3): 575-83, Oct 2014.

Omoloja Abiodun, Stolfi Adrienne, Chand Deepa, Laskin Benjamin, Gipson Debbie, Patel Hiren, Smith Jane Anne, Chishti Aftab: Tobacco exposure in children and adolescents with chronic kidney disease: parental behavior and knowledge. A study from the Midwest Pediatric Nephrology Consortium. Clinical nephrology 81(5): 307-12, May 2014.

Jodele Sonata, Davies Stella M, Lane Adam, Khoury Jane, Dandoy Christopher, Goebel Jens, Myers Kasiani, Grimley Michael, Bleesing Jack, El-Bietar Javier, Wallace Gregory, Chima Ranjit S, Paff Zachary, Laskin Benjamin L: Refined diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a prospective study in children and young adults. Blood 124(4): 645-53, May 2014.

Jodele Sonata, Fukuda Tsuyoshi, Vinks Alexander, Mizuno Kana, Laskin Benjamin L, Goebel Jens, Dixon Bradley P, Teusink Ashley, Pluthero Fred G, Lu Lily, Licht Christoph, Davies Stella M: Eculizumab therapy in children with severe hematopoietic stem cell transplantation-associated thrombotic microangiopathy. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20(4): 518-25, Apr 2014.

Springel Tamar, Laskin Benjamin, Furth Susan: Readmission within 30 days of hospital discharge among children receiving chronic dialysis. Clinical journal of the American Society of Nephrology : CJASN 9(3): 536-42, Mar 2014.

Lerner David, Dandoy Christopher, Hirsch Russell, Laskin Benjamin, Davies Stella M, Jodele Sonata: Pericardial effusion in pediatric SCT recipients with thrombotic microangiopathy. Bone marrow transplantation 49(6): 862-3, Mar 2014.

Posters and Presentations

2019

Levy Erez Daniella, Sullivan Kathleen E, Denburg Michelle, Bunin Nancy, Jodele Sonata, Afolayan Simisola, Wallace Gregory, Davies Stella, Laskin Benjamin. Urinary CXCL10 and CXCL9 are associated with acute kidney injury in children after hematopoietic stem cell transplantation: results of a discovery and validation cohort. poster presentation, Transplantation and Cellular Therapy Meeting, Houston Texas, 2019.

Laskin Benjamin, Denburg Michelle, Lowery Angela, Saycocie Phouvieng, Altrich Michelle, Kleiboeker Steve, Jodele Sonata, Lutzko Carolyn, Zhu Xiang, Duell Alexandra, Lake Kelly, Wallace Gregory, Davies Stella M. A prospective multi-center study of the natural history of BK viremia and host immune response in children after allogeneic hematopoietic cell transplant. Oral presentation by Dr. Laskin at the 2019 Transplantation and Cellular Therapy Meeting in Houston, Texas, February 20, 2019.

2018

Laskin Benjamin, Seif Alix E, Bunin Nancy J, Wang Yongping, Beier Ulf, Altrich Michelle, Kleiboeker Steve, Jodele Sonata, Davies Stella M, Denburg Michelle. BK viremia is common in children after allogeneic hematopoietic cell transplant. Oral presentation by Dr. Laskin at the 2018 Bone Marrow Transplant Tandem Meetings in Salt Lake City, Utah, February 24, 2018.

Meyers Melissa R, Schults Justine, Laskin Benjamin, Porrett Paige, Levine Matthew, Abt Peter, Amaral Sandi, Goldberg David S. Utilization of public health service increased risk kidneys in pediatric renal transplant recipients by era. poster presentation, Pediatric Academic Society/American Society of Pediatric Nephrology, Toronto, Ontario, 2018.

Meyers Melissa R, Shults Justine, Laskin Benjamin L, Porrett Paige, Levine Matthew, Abt Peter, Amaral Sandi, Goldberg David. Use of public health service increased risk kidneys in pediatric renal transplant recipients: recipient characteristics. poster presentation, Pediatric Academic Society/American Society of Pediatric Nephrology, Toronto, Ontario, 2018.

Myers Regina M, Getz Kelly D, Li Yimei, Huang Yuan-Shung V, Citrin Rebecca, Elgarten Caitlin W, Laskin Benjamin L, Horowitz Joseph P, Fisher Brian T, Aplenc Richard. Comparative effectiveness of rasburicase and allopurinol in children with acute lymphoblastic leukemia: an emulated pragmatic trial using observational data. Oral presentation by Dr. Regina Myers at the American Society of Hematology annual meeting, San Diego, California, December 3, 2018.

Meyers Melissa R, Shults Justine, Laskin Benjamin L, Porrett Paige, Levine Matthew, Abt Peter, Amaral Sandi, Goldberg David. Use of public health service increased risk kidneys in pediatric renal transplant recipients: recipient characteristics. poster presentation, American Transplant Congress Conference, Seattle, Washington, 2018.

Meyers Melissa R, Schults Justine, Laskin Benjamin, Porrett Paige, Levine Matthew, Abt Peter, Amaral Sandi, Goldberg David S. Utilization of public health service increased risk kidneys in pediatric renal transplant recipients by era. poster presentation, American Transplant Congress Conference, Seattle, Washington, 2018.

2016

Kakajiwala Aadil, Denburg Michelle, Jemielita Thomas, Hughes John, Windt Kimberly, Laskin Benjamin. : Factors affecting continuous renal replacement therapy circuit clotting in children. Poster presentation at the May 2016 Pediatric Academic Societies/American Society of Pediatric Nephrology Annual Meeting in Baltimore, MD 2016.

Awards and Honors

2013-2015, New Investigator Award/American Society for Blood and Marrow Transplantation

2011, Fellowship Scholarly Research Award/Cincinnati Children's Hospital Medical Center

2005, Faculty Medal of Honor/University of Maryland School of Medicine (Commencement Speaker)

2004, Alpha Omega Alpha Medical Society/University of Maryland School of Medicine (elected 3rd year)

Editorial and Academic Positions

Editorial Positions

Ad Hoc Referee

2016-present, PLoS ONE
2015-present, Lancet Hematology
2015-present, Transplantation
2015-present, Pediatric Blood and Cancer
2014-present, American Journal of Transplantation
2014-present, Blood
2014-present, Pediatrics
2013-present, Translational Research
2013-present, JAMA Pediatrics
2013-present, Pediatric Transplantation
2013-present, The Lancet
2012-present, Clinical Journal of the American Society of Nephrology
2011-present, Critical Care Medicine
2011-present, Pediatric Nephrology
2011-present, Clinical Nephrology
2011-present, European Journal of Pediatrics
2011-present, Kidney International
2010-present, American Journal of Kidney Diseases

Academic and Institutional Committees

2013-present, Department of Pediatrics, Electronic Health Record Quality and Safety group (SWATT: Specialists with Advanced Technical Training)
2013-present, Nephrology Division Champion, EPIC Electronic Health Record (EHR)

Leadership and Memberships

Memberships in Professional Organizations

2015-present, Society for Pediatric Research

2013-present, American Society of Transplantation

2011-present, American Society of Pediatric Nephrology

 - 2014-present, Education Committee, Co-Chair

2011-present, American Society of Nephrology

2011-present, American Society for Blood and Marrow Transplantation

 - 2014-Present, Grant Review Committee for New Investigator Awards

2008-present, Midwest Pediatric Nephrology Consortium