Chris A. Liacouras, MD
Areas of expertise: Allergic diseases of the GI tract, Endoscopy and colonoscopy, Eosinophilic disorders, Esophageal disorders, Gastroesophageal reflux disease (GERD), Hypercholesterolemia, Hyperlipidemia, Inflammatory bowel disease (IBD)
Locations: Specialty Care & Surgery Center, Brandywine Valley, Main Building, Specialty Care, King of Prussia
About Chris A. Liacouras, MD
Titles
Attending Physician
Professor of Pediatrics (Gastroenterology, Hepatology and Nutrition), Perelman School of Medicine at the University of Pennsylvania
Certifications
Diplomate – National Board of Medical Examiners (NBME)
Pediatric Gastroenterology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics
Awards and Honors
2022, Main Line Today Top Docs, Gastroenterology/Heptalogy
2022, Philadelphia Magazine's Top Doctors in Gastroenterology, Hepatology and Nutrition
1988-1990, Cystic Fibrosis Grant for Clinical Medicine
1982, Harvard Anatomy Award
1981, Delaware Valley Academic Award
1980, Phi Beta Kappa, Johns Hopkins University
Leadership and Memberships
Memberships in professional organizations
International
2008-present, The International Gastrointestinal Eosinophilic Researchers
- 2008-present, Education Committee, Chair
1992-present, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
National
1993-present, American Society of Gastrointestinal Endoscopy
Education & training
Undergraduate Degree
BA - Johns Hopkins University, Baltimore, MD
Medical Degree
MD - Harvard Medical School, Boston, MA
Internship
Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA
Residency
Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA
Fellowship
Pediatric Gastroenterology and Nutrition - The Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2021
Spergel JM, Muir AB, Liacouras CA, Burke D, Lewis MO, Brown-Whitehorn T, Cianferoni A: Sustained milk consumption after 2 years post-milk epicutaneous immunotherapy for eosinophilic esophagitis. Allergy 76: 1573-76, May 2021.
2020
Spergel JM, Elci OU, Muir AB, Liacouras CA, Wilkins BJ, Burke D, Lewis MO, Brown-Whitehorn T, Cianferoni A. : Efficacy of Epicutaneous Immunotherapy in Children with Milk-Induced Eosinophilic Esophagitis. Clin Gastroenterol hepatol 18: 328-36, Feb 2020.
Spergel JM, Elci OU, Muir AB, Liacouras CA, Wilkins BJ, Burke D, Lewis MO, Brown-Whitehorn T, Cianferoni A. : Efficacy of Epicutaneous Immunotherapy in Children with Milk-Induced Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 18: 328-36. Feb 2020
Spergel JM, Brown-Whitehorn TA, Muir A, Liacouras CA.: Medical algorithm: Diagnosis and treatment of eosinophilic esophagitis in children. Allergy. 75(6): 1522-1524, Jun 2020.
Spergel JM, Brown-Whitehorn TA, Muir A, Liacouras CA. : Medical algorithm: Diagnosis and treatment of eosinophilic esophagitis in children. Allergy. 75(6): 1522-4, June 2020.
Whelan KA, Godwin BC, Wilkins B, Elci OU, Benitez A, DeMarshall M, Sharma M, Gross J, Klein-Szanto AJ, Liacouras CA, Dellon ES, Spergel JM, Falk GW, Muir AB, Nakagawa H. : Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 18: 475-1482. Jun 2020
2018
Fahey LM, Chandramouleeswaran PM, Guan S, Benitez AJ, Furuta GT, Aceves SS, Wang ML, Liacouras CA, Muir AB, Sleiman PM, Hakonarson H, Spergel JM, Cianferoni A. : Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis. Clin Transl Gastroenterol. 9: 139. Mar 2018
Spergel JM, Dellon ES, Liacouras CA, Hirano I, Molina-Infante J, Bredenoord AJ, Furuta GT; : Summary of the updated international consensus diagnostic criteria for eosinophilic esophagitis: AGREE conference. Ann Allergy Asthma Immunol. S1081-1206, Jul 2018.
Dellon ES, Liacouras CA, et.al. : Updated international consensus diagnostic criteria for eosinophilic esophagitis: Proceedings of the AGREE conference. Gastroenterology. 2018. Gastroenterology 2018.
Spergel JM, Dellon ES, Liacouras CA, Hirano I, Molina-Infante J, Bredenoord AJ, Furuta GT. : Author's Response. Ann Allergy Asthma Immunol. 121(6): 747-748. Dec 2018.
2017
Friedlander JA, Liu QY, Sahn B, Kooros K, Walsh CM, Kramer RE, Lightdale JR, Khlevner J, McOmber M, Kurowski J, Giefer MJ, Pall H, Troendle DM, Utterson EC, Brill H, Zacur GM, Lirio RA, Lerner DG, Reynolds C, Gibbons TE, Wilsey M, Liacouras CA, Fishman DS;: Endoscopy Committee. NASPGHAN Capsule Endoscopy Clinical Report. J Pediatr Gastroenterol Nutr. 64(3): 485-94, March 2017.
Menard-Katcher C, Benitez AJ, Pan Z, Ahmed FN, Wilkins BJ, Capocelli KE, Liacouras CA, Verma R, Spergel JM, Furuta GT, Muir AB.: Influence of Age and Eosinophilic Esophagitis on Esophageal Distensibility in a Pediatric Cohort. Am J Gastroenterol. May 2017.
Atkins D, Furuta GT, Liacouras CA, Spergel JM. : Eosinophilic esophagitis phenotypes: Ready for prime time? Pediatr Allergy Immunol. 28(4): 312-9, June 2017.
Ruffner MA, Brown-Whitehorn TF, Verma R, Cianferoni A, Gober L, Shuker M, Muir AB, Liacouras CA, Spergel JM.: Clinical tolerance in eosinophilic esophagitis. J Allergy Clin Immunol Pract. . Page: S2213, 2017.
2016
Muir AB, Wang ML, Metz D, Falk G, Markowitz J, Spergel JM, Liacouras CA.: Proton pump inhibitor-responsive oesophageal eosinophilia: too early to change clinical practice. Gut. 2016.
Dellon ES, Collins MH, Bonis PA, Leung J, Capocelli KE, Dohil R, Falk GW, Furuta GT, Menard-Katcher C, Gupta SK, Hirano I, Hiremath GS, Kagalwalla AF, Wershil BK, Liacouras CA, Muir AB, Mukkada VA, Putnam PE, Schoepfer AM, Straumann A, Wo JM, Yang GY, Rothenberg ME, Gonsalves N.: Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders. Clin Gastroenterol Hepatol. Page: S1542, April 2016.
2015
Ram G, Lee J, Ott M, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Verma R, Liacouras CA, Spergel JM.: Seasonal exacerbation of esophageal eosinophilia in children with eosinophilic esophagitis and allergic rhinitis. Ann Allergy Asthma Immunol. 115: 224-8, September 2015.
2014
Liacouras CA, Spergel J, Gober LM.: Eosinophilic Esophagitis: Clinical Presentation in Children. Gastroenterol Clin North Am. 43(2): 219-29, June 2014.
Maggadottir SM, Hill DA, Ruymann K, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Chikwava K, Verma R, Liacouras CA, Spergel JM. : Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same food. J Allergy Clin Immunol 133(5): 1487-9, May 2014.
2013
Menard-Katcher P, Marks KL, Liacouras CA, Spergel JM, Yang YX, Falk GW.: The natural history of eosinophilic oesophagitis in the transition from childhood to adulthood. Aliment Pharmacol Ther. 37(1): 114-21, January 2013.
Menard-Katcher P, Marks KL, Liacouras CA, Spergel JM, Yang YX, Falk GW.: The natural history of eosinophilic oesophagitis in the transition from childhood to adulthood. Aliment Pharmacol Ther. 37(1): 114-21, January 2013.
Dellon ES, Gonsalves N, Hirano I, Furuta GT, Liacouras CA, Katzka DA;: ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE). Am J Gastroenterol. 108(5), May 2013.
2012
Rothenberg ME, Aceves S, Bonis PA, Collins MH, Gonsalves N, Gupta SK, Hirano I, Liacouras CA, Putnam PE, Spergel JM, Straumann A, Wershil BK, Furuta GT.: Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis. J Allergy Clin Immunol 130(3): 617-9, Sept 2012.
Spergel JM, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Verma R, Liacouras CA. : Identification of causative foods in children with eosinophilic esophagitis treated with an elimination diet. J Allergy Clin Immunol. 2012 Aug;130(2):461-467.e5. 2012.
Spergel JM, Rothenberg ME, Collins MH, Furuta GT, Markowitz JE, Fuchs G 3rd, O'Gorman MA, Abonia JP, Young J, Henkel T, Wilkins HJ, Liacouras CA. : Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2012 Feb;129(2):456-63, 2012.
2011
Liacouras CA. Clinical presentation and treatment of pediatric patients with eosinophilic esophagitis. Gastroenterol Hepatol (NY). 2011 Aprl7(4):264-7. Cited in PubMed; PMCID: PMC 3127030.
2010
Franciosi JP, Fiorino K, Ruchelli E, Shults J, Spergel J, Liacouras CA, et al. Changing indications for upper endoscopy in children during a 20-year period. J Pediatr Gastroenterol Nutr. 2010 Jun 16. Cited in PubMed; PMCID: PMC 2946469.
2009
Goldberg E, Barton S, Xanthopoulos MS, Stettler N, Liacouras CA. A descriptive study of complications of gastrostomy tubes in children. J Pediatr Nurs. 2010 Apr 25(2):72-80. Epub 2009 May 30. Cited in PubMed; PMID 20185057.
Spergel JM, Brown-Whitehorn TF, Beausoleil JL, Franciosi J, Shuker M, Verma R, et al. 14 years of eosinophilic esophagitis: clinical features and prognosis. J Pediatr Gastroenterol Nutr. 2009 Jan;48(1):30-6. Cited in PubMed; PMID 19172120.
Books
Liacouras CA : EMedicine internet textbook emedicine in press
Liacouras CA: Clinical Pediatric Gastroenterology. Churchill-Livingstone, New York, NY. Altschuler SM (eds.). 1998.
Liacouras CA (assistant editor). : Pediatric Secrets. Hanley and Belfus, Inc, Philadelphia, PA. Ditmar MF and Polin RA (eds.). 1993.
Editorials, Reviews, Chapters
2016
Markowitz J, Liacouras CA.: Allergic and Eosinophilic Gastrointestinal Disease. In: Pediatric Gastrointestinal and Liver Disease. Wyllie, Hyams and Kay (eds 2016.
2015
Liacouras CA.: Gastroenterology. 2015. In: Pediatric Secrets; Polin RA, Ditmar MA (eds), 2015.
2014
Liacouras CA: Multiple Chapters. Nelson's Pediatric Textbook 2014.
2008
Furuta G, Liacouras CA. Eosinophilic esophagitis. In: Kleinman, Goulet, et al., editors. Pediatric gastrointestinal disease. 2008. p. 575-82.
2006
Kamath BM, Markowitz JE, Liacouras CA. Allergic bowel disease and eosinophilic gastroenteritis. In: Wyllie, Hyams, editors. Pediatric gastrointestinal disease and liver disease. 2006. pp. 543-56.
2005
Graham-Maar R, Ryan M, Liacouras CA. Abdominal masses. In: Schwartz MW, editor. The 5-minute pediatric consult. Baltimore: Williams & Wilkins; 2005.
vomiting. In: Schwartz MW, ed. The 5-minute Pediatric Consult. Baltimore, MD. Williams and Wilkins, 2005.
2004
Markowitz J, Liacouras CA. Eosinophilic disorders of the gastrointestinal tract. In: Wyllie, Hyams, editors. Pediatric gastrointestinal disease. 2004. p. 245-9.
Durbin D, Liacouras CA. Gastrointestinal emergencies. In: Ludwig, Fleisher, editors. Pediatric emergency medicine. 4th ed. 2004. p. 1113-1140.
Friedman JR, Liacouras CA. Pathophysiology of gastroesophageal reflux. In: Polin RA, Fox WW, editors. Fetal and neonatal physiology. Philadelphia, PA: W.B. Saunders Co.; 2004. p. 1163-68.
2003
Liacouras CA, Markowitz J. Eosinophilic esophagitis and gastroenteritis. In: Sampson, editor. Pediatric allergy. 2003. p. 518-528.
2002
Markowitz J, Liacouras CA. Gastroesophageal reflux. In: Polin RA, Ditmar M, editors. Neonatal secrets. 2002.
Markowitz J, Mamula P, Liacouras CA. Gastroenterology. In: Polin RA, Ditmar M, editors. Pediatric secrets. 2002.
2001
Liacouras CA. Abdominal masses; Vomiting; Hyperlipidemia;Diarrhea In: Schwartz MW, ed. The 5-minute Pediatric Consult. Baltimore, MD. Williams & Wilkins; 2001.
1999
Durbin D, Liacouras CA. Gastrointestinal emergencies. In: Ludwig S, Fleischer GR, editors. Pediatric emergency medicine. 4th ed. 1999. p. 1017-43.
1998
Liacouras CA, Altshuler SM. Pathophysiology of gastroesophageal reflux. In: Polin RA, Fox WW, editors. Fetal and neonatal physiology. Philadelphia: W.B. Saunders Co.; 1998. p. 1418-24.
Liacouras CA. Celiac disease. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 60-1.
Liacouras CA. Inflammatory bowel disease. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 176-177.
Liacouras CA. Hepatitis, acute viral. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 146-147.
Liacouras CA. Hepatitis, chronic. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 148-149.
Liacouras CA. Hepatosplenomegaly. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 149-150.
Liacouras CA. Constipation. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 74-75.
Liacouras CA. Esophagitis. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 114-115.
Liacouras CA. Foreign body, gastrointestinal. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 124-125.
Liacouras CA. Gastrointestinal bleeding. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 128-129.
Liacouras CA. Vomiting. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 316-317.
Liacouras CA. Infectious diarrhea. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 174-175.
Liacouras CA. Lactose intolerance. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 184-185.
Liacouras CA. Abdominal masses. In: Ludwig S, Altschuler SM, editors. Pediatrics at a glance. Philadelphia: Mosby; 1998. p. 2-3.
Liacouras CA. Abdominal masses. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 1-4.
Jeshion W, Liacouras CA. Clostridium difficile. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 151-4.
Arnold LA, Liacouras CA. Foreign bodies and caustic ingestions. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 25-30.
Liquornik K, Liacouras CA. Upper Endoscopy. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 537-40.
Peck S, Liacouras CA, Redd DA. Percutaneous gastrostomy tubes. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 627-36.
Liacouras CA. Pancreatic function tests. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 583-4.
Liacouras CA, Kader H. Abdominal pain. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 5-8.
Sentongo T, Liacouras CA. Shwachmans syndrome. In: Altschuler SM, Liacouras CA, editors. Clinical pediatric gastroenterology. London (England): Churchill-Livingstone; 1998. p. 307-8.
Liacouras CA. Vomiting. In: Schwartz MW, editor. Clinical handbook of pediatrics, 2nd ed. Baltimore: Williams & Wilkins; 1998. p. 693-703.
Liacouras CA. Lower GI bleeding. In: Schwartz MW, editor. Clinical handbook of pediatrics, 2nd ed. Baltimore: Williams & Wilkins; 1998. p. 318-24.
Liacouras CA. Upper GI bleeding. In: Schwartz MW, editor. Clinical handbook of pediatrics, 2nd ed. Baltimore: Williams & Wilkins; 1998. p. 308-18.
1996
Liacouras CA, Tershakovec A, Cortner JA. Hyperlipidemia. In: Watkins JB, Walker WA. Nutrition in Pediatrics. pp 611-23, 1996.
Liacouras CA, Piccoli DA. Gastroenterology and Nutrition. In: Polin RA, Ditmar MF. Pediatric Secrets. Hanley and Belfus, Inc., 1996, pp. 161-99.Liacouras CA. Abdominal masses. In: Schwartz MW, editor. The 5-minute pediatric consult. Baltimore: Williams and Wilkins; 1996. p. 2-3.
Liacouras CA. Vomiting. In: Schwartz MW, editor. The 5-minute pediatric consult. Baltimore: Williams and Wilkins; 1996. p. 64-65.Liacouras CA. Hyperlipidemia. In: Schwartz MW, editor. The 5-minute pediatric consult. Baltimore: Williams and Wilkins; 1996. p. 414-415.Liacouras CA. Diarrhea. In: Schwartz MW, editor. The 5-minute pediatric consult. Baltimore: Williams and Wilkins; 1996. p. 414-415.