Gary W. Nace, Jr., MD

Gary W. Nace, Jr., MD

Gary W. Nace, Jr., MD, is an attending pediatric surgeon with the Division of Pediatric General, Thoracic and Fetal Surgery at Children's Hospital of Philadelphia.

Areas of Expertise: Minimally invasive surgery, Thoracic Surgery, Emergency Department/Trauma, Neonatal Surgery, Oncologic Surgery
Locations: Main Campus; Specialty Care & Surgery Center, Voorhees; Specialty Care, Princeton at Plainsboro
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Temple University School of Medicine, Philadelphia, PA

Internship

General Surgery - University of Pittsburgh Medical Center, Pittsburgh, PA

Residency

General Surgery - University of Pittsburgh Medical Center, Pittsburgh, PA

Fellowship

Pediatric Surgery - Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

Board Certification

General Surgery
Pediatric Surgery

Titles and Academic Titles

Attending Surgeon

Departments and Services

Publications

Papers

2016

De La Torre L, Cogley K, Calisto J, Nace G, Correa C. Primary sigmoidectomy andappendicostomy for chronic idiopathic constipation. Pediatr Surg Int. 2016 Aug;32(8):767- 72. Pubmed PMID: 27372298.

2015

Leeper CM, Nace G, Scholz S. Gallbladder and Biliary Tract; In: Diagnostic and Interventional Ultrasound in Pediatrics and Pediatric Surgery. Scholz S & Jarboe M, Eds. Springer, 2015.

2014

Tohme S, Sukato D, Nace GW, Zajko A, Amesur N, Orons P, Chalhoub D, Marsh JW,Geller DA, Tsung A. Survival and tolerability of liver radioembolization: a comparison of elderly and younger patients with metastatic colorectal cancer. HPB (Oxford). 2014 Dec;16(12):1110-6. PubMed PMID: 25123597.

2013

Huang H*, Nace GW*, McDonald KA, Tai S, Klune JR, Rosborough BR, Ding Q, Loughran P, Zhu X, Beer-Stolz D, Chang EB, Billiar T, Tsung A. Hepatocyte specific HMGB1 deletion worsens the injury in liver ischemia/reperfusion: A role for intracellular HMGB1 in cellular protection. Hepatology. 2013 Dec 21. [Epub ahead of print] PubMed PMID: 24375466.

Huang H, Chen HW, Evankovich J, Yan W, Rosborough BR, Nace GW, Ding Q, Loughran P, Beer-Stolz D, Billiar TR, Esmon CT, Tsung A. Histones Activate the NLRP3 Inflammasome in Kupffer Cells during Sterile Inflammatory Liver Injury. J Immunol. 2013 Sep 1;191(5):2665-79. PubMed PMID: 23904166.

Nace GW, Huang H, Klune JR, Eid RE, Rosborough BR, Korff S, Li S, Shapiro RA, Stolz DB, Sodhi CP, Hackam DJ, Geller DA, Billiar TR, Tsung A. Cellular-specific role of tolllike receptor 4 in hepatic ischemia-reperfusion injury in mice. Hepatology. 2013 Jul;58(1):374-87. doi: 10.1002/hep.26346. Epub 2013 May 27. PubMed PMID: 23460269; PubMed Central PMCID: PMC3688695.

Tsung A, Nace GW, Geller DA. Pituitary adenylate cyclase-activating polypeptide: a neuromodulator of hepatic ischemia-reperfusion injury? Hepatology. 2013 Mar;57(3):878- 80. doi: 10.1002/hep.25902. PubMed PMID: 22729815.

2012

Chang Y, Yan W, He X, Zhang L, Li C, Huang H, Nace G, Geller DA, Lin J, Tsung A. miR-375 inhibits autophagy and reduces viability of hepatocellular carcinoma cells under hypoxic conditions. Gastroenterology. 2012 Jul;143(1):177-87.e8. doi: 10.1053/j.gastro.2012.04.009. Epub 2012 Apr 12. PubMed PMID: 22504094.

Klune JR, Dhupar R, Kimura S, Ueki S, Cardinal J, Nakao A, Nace G, Evankovich J, Murase N, Tsung A, Geller DA. Interferon regulatory factor-2 is protective against hepatic ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1;303(5):G666-73. doi: 10.1152/ajpgi.00050.2012. Epub 2012 Jun 28. PubMed PMID: 22744333; PubMed Central PMCID: PMC3468551.

Zhang L, Cardinal JS, Bahar R, Evankovich J, Huang H, Nace G, Billiar TR, Rosengart MR, Pan P, Tsung A. Interferon regulatory factor-1 regulates the autophagic response in LPS-stimulated macrophages through nitric oxide. Mol Med. 2012 Mar 27;18(1):201-8. doi: 10.2119/molmed.2011.00282. PubMed PMID: 22105605; PubMed Central PMCID: PMC3320143.

2011

Nace G, Evankovich J, Eid R, Tsung A. Dendritic cells and damage-associated molecular patterns: endogenous danger signals linking innate and adaptive immunity. J Innate Immun. 2012;4(1):6-15. Epub 2011 Nov 11. Review. PubMed PMID: 22086146.

Huang H, Evankovich J, Yan W, Nace G, Zhang L, Ross M, Liao X, Billiar T, Xu J, Esmon CT, Tsung A. Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice. Hepatology. 2011 Sep 2;54(3):999-1008. doi: 10.1002/hep.24501. PubMed PMID: 21721026; PubMed Central PMCID: PMC3213322

Nace GW, Steel JL, Amesur N, Zajko A, Nastasi BE, Joyce J, Sheetz M, Gamblin TC. Yttrium-90 radioembolization for colorectal cancer liver metastases: a single institution experience. Int J Surg Oncol. 2011;2011:571261. Epub 2011 Mar 20. PubMed PMID: 22312513; PubMed Central PMCID: PMC3263679.

2010

Nace G, Lee K, Bartels C. Endocrine Pancreas; In: Surgical Oncology: Fundamentals, Evidence Based Approaches and New Technologies. Bartlett D, Ed. Jaypee Brothers medical publishers, 2010.

2009

Nace, Gary and Gamblin, Clark. 90-Yttrium Microsphere Radioembolization in the Treatment of Primary and Metastatic Liver Tumors. US Gastroenterology. 2009; 4:36-38.

2007

Chen CY, Nace GW, Solow B, Fratamico P. Complete nucleotide sequences of 84.5- and 3.2-kb plasmids in the multi-antibiotic resistant Salmonella enterica serovar Typhimurium U302 strain G8430. Plasmid. 2007 Jan;57(1):29-43. Epub 2006 Jul 7. PubMed PMID: 16828159.

2003

Chen CY, Nace GW, Irwin PL. A 6 x 6 drop plate method for simultaneous colony counting and MPN enumeration of Campylobacter jejuni, Listeria monocytogenes, and Escherichia coli. J Microbiol Methods. 2003 Nov;55(2):475-9. PubMed PMID: 14529971.

Awards and Honors

2011, “Best Poster” at 3rd International HMGB1 Conference, Pittsburgh, PA
2010, Association for Academic Surgery Foundation Fellowship Research Award
2007, W. Emory Burnett Prize in Surgery
2005, Augustin Peale Award for Excellence in Pathology
2004, Benjamin and Mary Siddons Measey Foundation Medical Student Scholarship
2004, John Franklin Huber Award in Anatomy