Lisa J. States, MD

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Lisa J. States, MD, is a pediatric radiologist, with additional expertise in nuclear medicine, the Director of the Section of Oncologic Imaging and the Endowed Chair in Molecular Imaging at Children's Hospital of Philadelphia.

Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)


Education and Training

Medical School

MD - Cornell University Medical Center, New York, NY

Internship

Internal Medicine - Danbury Hospital, Danbury, CT

Residency

Radiology - Albert Einstein College of Medicine/ Montefiore Medical Center, Bronx, NY (Chief Resident)

Fellowship

Pediatric Radiology - University of Pennsylvania Medical School, The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Diagnostic Radiology
Pediatric Radiology
Radiology

Titles and Academic Titles

Director, Section of Oncologic Imaging

Principal Investigator, 18F-DOPA PET Research Studies

Endowed Chair for Molecular Imaging

Professor of Clinical Radiology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2021

Dillman, Jonathan; Gee, Michael; Ward, Christopher; Drum, Elizabeth; Servaes, Sabah; Jaimes, Camilo; States, Lisa: Imaging Sedation and Anesthesia Practice Patterns in Children - A Survey of the Society of Chairs of Radiology at Children's Hospitals (SCORCH). Pediatric Radiology  January 2021.

Samoyedny A, Srinivasan A, States L, Mosse YP, Alai E, Pawel B,  Pogoriler J,  Shellikeri S, Vatsky S, Acord M, Escobar F,  Edgar JC,  Maris JM,  Cahill AM: Image-Guided Biopsy for Relapsed Neuroblastoma: Focus on Safety, Adequacy for Genetic Sequencing and Correlation with Tumor Percent with Quantitative Lesion MIBG Uptake.   JCO Precision Oncology March  2021.

Eweje FR, Bao B, Wu J, Dalal D, Liao WH, He Y, Luo Y, Lu S, Zhang P, Peng X, Sebro R, Bai HS, States L: Deep Learning for Classification of Bone Lesions on Routine MRI. EBio Medicine June 2021 Notes:  doi: 10.1016/j.ebiom.2021.103402. Epub 2021 Jun 5.PMID: 34098339

Peng J, Kim DD, Patel JB, Zeng X, Huang J, Chang K, Xun X, Zhang C, Sollee J, Wu J, Dalal DJ, Feng X, Zhou H, Zhu C, Zou B, Jin K, Wen PY, Boxerman JL, Warren KE, Poussaint TY, States LJ, Kalpaty-Cramer J, Yang L, Huang RY, Bai HX.: Deep Learning-Based Automatic Tumor Burden Assessment of Pediatric High Grade Gliomas, Medulloblastomas, and other Leptomeningeal Seeding Tumors.  Neuro Oncol 26, June 2021 Notes: doi: 10.1093/neuonc/noab151. Online ahead of print.

Baratto, L., Hawk, K. E., States, L., Qi, J., Gatidis, S., Kiru, L., & Daldrup-Link, H. E: PET/MRI Improves Management of Children with Cancer. Journal of nuclear medicine: official publication, Society of Nuclear Medicine 62(10): 1334-1340, October 2021 Notes: DOI: 10.2967/jnumed.120.259747.

2020

Jeffrey P Schmall, Suleman Surti, Hansel Otero, Sabah Servaes, Joel S. Karp and Lisa J. States: Investigating low-dose image quality in whole-body pediatric 18F-FDG scans using TOF-PET/MRI. Journal of Nuclear Medicine June 2020 Notes: First published June 1, 2020, doi: 10.2967/jnumed.119.240127, Online ahead of print as of October 2020.

He Y, Pan I, Bao B, Halsey K, Chang M, Liu H,Peng S, Sebro RA, Guan J, Yi B, Delworth AT, Feyisope E, States LJ, Zhang PJ, Zhang Z, Wu J, Peng X, Bai HX: Deep Learning-Based Classification of Primary Bone Tumors on Radiographs: A Preliminary  EBioMedicine. Elsevier, 62 : 103121, November 2020 Notes: DOI:https://doi.org/10.1016/j.ebiom.2020.103121.

2019

Zadeh MZ, Wen Z, States LJ, Zhuang H. An Isolated Osseous Rosai-Dorfman Disease Shown on FDG PET/CT. Clinical Nuclear Medicine, 44 (6): 485-488. Doi: 10.1097/RLU.0000000000002501. June 2019.

Kwatra NS, Lim R, Gee MS, States LJ, Vossough A, Lee EY (2019 May). PET/MR Imaging: Current Updates on Pediatric Applications. Magnetic Resonance Imaging Clinics in North America, 27 (2): 387-407. Doi: 10.1016/j.mric.2019.01.012. 

2018

Adzick NS, De Leon DD, States LJ, Lord K, Bhatti TR, Becker SA, Stanley CA. Surgical treatment of congenital hyperinsulinism: Results from 500 pancreatectomies in neonates and children. J Pediatr Surg. 2019 Jan;54(1):27-32. doi: 10.1016/j.jpedsurg.2018.10.030. Epub 2018 Oct 5.

2017

MacFarland SP, Mostoufi-Moab S, Zelly K, Mattei PA, States LJ, Bhatti TR, Duffy KA, Brodeur GM, Kalish JM. Management of Adrenal Masses in Patients with Beckwith-Wiedemann Syndrome. Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26432. Epub 2017 Jan 9.

Yang M1, Sun J, Bai HX, Tao Y, Tang X, States LJ, Zhang Z, Zhou J, Farwell MD, Zhang P, Xiao B, Yang L.: Diagnostic accuracy of SPECT, PET, and MRS for primary central nervous system lymphoma in HIV patients: A systematic review and meta-analysis. Medicine (Baltimore). 2017 May;96(19):e6676. doi: 10.1097/MD.0000000000006676.

2016

Bagatell R, McHugh K, Naranjo A, Collin Van Ryn, Kirgy C, Brock P, Lyons KA, States LJ, Rojas Y, Miller A, Volchenboum SL, Simon T, Krug B, Sarnacki S, Valteau-Couanet D, von Schweinitz, D, Krammer B, Granata C, Pio L, Park JR, Nuchtern J. Assessment of Primary Site Response in Children with High-Risk Neuroblastoma: An International Multicenter Study. J Clin Oncol. 2016 Mar 1;34(7):740-6. doi: 10.1200/JCO.2015.63.2042. Epub 2016 Jan 11.

Books

Chapters

2020

Sammer MB, Sher AC, States LJ, Trout AT, Seghers VJ: Current trends in pediatric nuclear medicine: a Society for Pediatric Radiology membership survey. Pediatric Radiology. Springer, 50: 1139-1147, May 2020.

2019

States LJ, Mohnike H: 18F-DOPA PET Congenital Hyperinsulinism. A Practical Guide to Diagnosis and Management. Diva D. De Leon-Crutchlow and Charles A. Stanley (eds.). Springer Nature Switzerland AG, Page: 85-93, January 2019 Notes: Invited Chapter.

States LJ, Voss S: PET/CT in Pediatric Oncology. Imaging in Pediatric Oncology. Voss SD, McHugh K (eds.). Springer Nature Switzerland AG, Page: 29-61, January 2019 Notes: Book chapter.

2018

States LJ, Reid JR.: Ionizing Radiation Use and Cancer Predisposition Syndromes in Children. Journal of the American College of Radiology. Elsevier, 15(9): 1238-1239, September 2018.

Hernandez-Schulman M, States, LJ, Vasanawala, S: Gastrointestinal System: Chapter 84 Imaging Techniques. Caffey's Pediatric Diagnostic Imaging, 13th edition. Coley, Brian D (eds.). Elsevier Saunders, 13, May 2018.

2012

States, LJ and Adzick, NS: Localization of a focal Lesion of congenital Hyperinsulinism:  Imaging and surgery. Monogenic Hyperinsulinemic Hypoglycemia Disorders, Frontiers in Diabetes  Stanley CA, DeLeon DD  (eds.). Basel, Karger, 21: 71-78, 2012.

Posters and Presentations

2022

Elsingergy M, Sridharan A, Poznick L, Morgan T, Makhethe V, Khrichenko D, Hansel O, States L, Darge K.: 3D Ultrsound, Magnetic Resonance Urography, Urinary tract dilatation. Pediatric Radiology 2022 Notes: SPR presentation.

Elsingergy M, Sridharan A, Poznick L, Morgan T, Vuma M, Otero H, States L, Darge K,  Back SJ.: Feasibility of renal 3D US and detection of urinary tract obstruction compared with MAG3 renal scan Pediatric Radiology 2022 Notes: SPR oral presentation and poster.

Ghosh A, Dalal D, Holroyd AJ, States L: Whole-Tumor Apparent Diffusion Coefficient (ADC) Histogram Analysis to Identify MYCN Amplification in Neuroblastomas. Pediatric Radiology 2022 Notes: SPR oral presentation.

Mohamed Elsingergy; Anush Sridharan; Laura Poznick; Trudy Morgan; Makhethe Vuma; Dmitry Khrichenko; Hansel Otero: Lisa States; Kassa Darge; Susan J. Back.: Feasibility of renal 3D US to measure renal parenchymal volume compared to MRU Pediatric Radiology 2022 Notes: SPR presentation and poster.

2021

Navarathna N, Becker S, Dalal D, Edgar C, De Leon D, Sigal W, Lord K, States L.: 18F-FDOPA PET Imaging in Congenital Hyperinsulinism for Localization of a Focal Pancreatic Lesion: Do Medications Interfere With Radiotracer Uptake? 2021 Congenital Hyperinsulinism Research Conference September 2021 Notes: Presentation.

2020

Bedoya, Maria; Barrera, Christian; Ho-fung, Victor; States, Lisa: Can Pigtail or Narrow Curve Morphology be an Additional Finding Used to Exclude Appendicitis in Questionable Case. Society for Pediatric Radiology, Annual Meeting and Postgraduate Course, on-line May 2020 Notes: Paper presentation #: 002 (S).

Davis, James; Servaes, Sabah; Nevo, Elad; States, Lisa: Dose Reduction in PET/MRI in Young Pediatric Patients Under 5 years of Age. Society for Pediatric Radiology, Annual Meeting and Postgraduate Course, on-line May 2020 Notes: Paper presentation #: 139.

Dillman Jonathan, Gee Michael, Ward Christopher, Drum Elizabeth, Servaes Sabah, Jaimes Camilo, States Lisa: Imaging Sedation and Anesthesia Practice Patterns in Children Under 6 Months of Age - A Survey of the Society of Chairs of Radiology at Children's Hospitals (SCORCH). Society for Pediatric Radiology, Annual Meeting and Postgraduate Course, on-line May 2020 Notes: Poster presentation.

El-ali Alexander, Mittal Sameer, Boyer Kathleen, Long Christopher, States Lisa, Back Susan, Khrichenko Dmitry, Serai Suraj: Quantitative MRI Biomarkers in Pediatric Nephron Sparing Surgery. Society for Pediatric Radiology, Annual Meeting and Postgraduate Course, on-line May 2020 Notes: Poster presentation.

Gillman J, Servaes S, States LJ: The use of FDG-PET/CT in pediatric post-transplant lymphoproliferative disorder (PTL). Society for Nuclear Medicine and Molecular Imaging Annual Meeting, virtual meeting May 2020 Notes: Poster presentation.

Holroyd A, Bai H, Lui S, Xiao Y, Liu Y, Wu J, States L: Prediction of the MYCN status in Neuroblastoma Using MR-based Radiomics. Society for Pediatric Radiology, Annual Meeting and Postgraduate Course, on-line May 2020 Notes: Oral presentation (canceled due to COVID-19).

Holroyd AJ, Khrichenko D, States L: Radiogenomics of Neuroblastoma: Quantitative MRI and Genetic Data Analysis. Society for Pediatric Radiology, Annual Meeting and Postgraduate Course, on-line May 2020 Notes: Oral presentation (canceled due to COVID-19).

McElroy K, Binkovitz L, Trout A, Czachowski M, Seghers V, Lteif A, States L, Laack N, Ahmed S: Pediatric Theranostic Applications of Dotatate: Early Clinical Experience. Society for Pediatric Radiology, Annual Meeting and Postgraduate Course, on-line May 2020 Notes: Poster Presentation (posters displayed on-line), (canceled due to COVID-19).

Lectures by Invitation

2022

States LJ. Pediatric WBMRI in CPS: Getting Started, ISMRM-ESMRMB and the ISMRT 31st Annual Meeting, London, England, UK. May 2022.

States LJ. 18F-FDOPA for Hypoglycemia, High Country Nuclear Medicine Conference, Sun Valley Idaho. Mar 2022.

States LJ. Nuclear medicine after dark: GI bleed imaging in children, SNMMI, mid winter meeting, Virtual. Feb 2022.

2021

States LJ. "WholeBody MRI Imaging in Cancer Predisposition Syndromes" Radiologic Society of North America, Chicago, Illinois. Dec 2021.

States LJ. MRI whole body imaging in children, RSNA, Chicago. Dec 2021.

States LJ. MRI whole body imaging of CPS in children. Dec 2021.

States LJ. Whole-body MRI Surveillance for Children with Cancer Predisposition Syndromes, RSNA, Chicago. Nov 2021.

States LJ. Use of 18F-DOPA PET/CT in Children with Hyperinsulinsm, IPR, International Pediatric Radiology Congress, Rome. Oct 2021.

States LJ. "Imaging of Hyperinsulinism",  International Society of Pediatric Radiology, Rome, Italy. Oct 2021.

States LJ. "Tumor Evaluation with 68Ga-DOTATATE", Children's Hospital Colorado, Virtual lecture. Sept 2021.

States LJ. Imaging of Hyperinsulinism, International society for pediatric imaging, Rome. July 2021.

States LJ. Imaging of BWS,  Beckwith Wiedemann Symposium, Philadelphia. July 2021.

States LJ. "Radiology Findings in BWSp" Deciphering Beckwith-Wiedemann Spectrum, Children's Hospital of Philadelphia, Philadelphia, PA. July 2021.

States LJ. "Nuclear Medicine-Nuts and Bolts", Resident Conference, Northwell Health, Virtual. May 2021.

States LJ. "PET Imaging in Pediatric Oncology", Pediatric Grand Rounds, Northwell Health, Virtual. May 2021.

States LJ. PET/MR Imaging Applications in Pediatrics 10th SEHA International Radiology Conference, Abu Dhabi, UAE. Virtual. Feb 2021

States LJ. Whole-Body MRI Surveillance for Children with Cancer Predisposition Syndromes, 10th SEHA International Radiology Conference. Abu Dhabi, UAE. Virtual. Feb 2021.

States LJ. "15 Year old with HTN and Neck Mass," American Society of Pediatric Nephrology Renal Imaging Course - Webinar Series, American Society of Pediatric Nephrology, Virtual. Feb 2021.

States LJ. "Imaging of Hyperinsulinism" Society For Pediatric Radiology, Neonatal Imaging Course, Virtual. Jan 2021.

2020

States LJ. Pediatric PET/MR. Signa Masters GE PET/MR summit - Pediatrics, Virtual. Nov 2020.

States LJ. "Cutting edge PET/MR," Society of Nuclear Medicine and Molecular Imaging, New Orleans, LA (Cancelled due to Covid-19). Jun 2020.

Awards and Honors

2021, Outstanding CRISSP Poster Award in Behavioral/Clinical Research

2019, Endowed Chair of Molecular Imaging, Children's Hospital of Philadelphia

2019, Outstanding CRISSP (The CHOP Research Institute Summer Scholars Program) Poster Award in Behavioral/Clinical Research

2019, Awarded for Detection of a Focal Lesion of Congenital Hyperinsulinism using 18F-DOPA PET/CT scan: Lessons learned from 100 consecutive studies with histologic confirmation performed at Children's Hospital of Philadelphia

2018, Majd-Gilday Young Investigator Award (YIA) Pediatric Imaging Council, "Investigating low-dose image quality in whole-body pediatric 18F-FDG scans using TOF-PET/MRI" Recipient : Jeff Schmall (Mentee)

2018, "Be My Sugar Award For Medical Excellence," Awarded by: Congenital Hyperinsulinism International

2017, John Caffey Society

2014, Top Doctor in Plymouth Meeting, PA

2014, International Association of Radiologists 

2014, The Leading Physicians of the World publication

2002, Clinical Investigator Award for Research in Women's Health, The University of Pennsylvania School of Medicine, Department of Pediatrics

2002, Top 10% of Teaching Faculty, Department of Radiology, University of Pennsylvania School of Medicine,

1994, Milton Elkin Award, Most Outstanding Graduating Resident, Albert Einstein College of Medicine/Montefiore Medical Center Unified Program

1988, Papanicolau Fellow, Department of Anatomy, Weill Cornell Medical College Outstanding Medical Student and Teaching Assistant

Editorial and Academic Positions

Editorial Positions

2020-present, Editorial Board, The Journal of Nuclear Medicine (JNM)
2019-present, Ad-hoc reviewer, European Journal of Pediatrics
2018-present, Ad-hoc reviewer, Philadelphia Pediatric Medical Device Consortium, Philadelphia, PA
2017-present, Ad-hoc reviewer, Journal of Visualized Experiments
2016-present, Ad-hoc reviewer, Future Oncology
2016-present, Ad-hoc reviewer, Clinical Nuclear Medicine
2011-present, RadiologyInfo.org Content Reviewer, RSNA-ACR Public Website Medical Advisor
2010-present, Ad-hoc Reviewer, Pediatric Radiology
2009-present, Co-editor, American College of Radiology Case in Point
2009-present, Ad-hoc Reviewer, European Journal of Nuclear Medicine
2009-present, Ad-hoc Reviewer, Pediatric Radiology
 

Academic and Institutional Committees

2021-2024, Research Institute Equity, Diversity and Inclusion Council
2021-present, CRISSP Faculty Advisory Committee
2021-present, Research Institute's Diversity, Equity and Inclusion Council
2021-present, Diversity, Inclusion and Equity Council (DIECR) of the Department of Radiology
2021-present, Congenital Hyperinsulinism International Collaborative Research Network
2020-present, Illumina Radiopharmaceuticals clinical trial review committee
2020-present, Faculty Advisory Committee, CHOP Research Institute Summer Scholars Program (CRISSP)
2020-present,CRISSP Faculty Advisory Committee
2019-present, Advisory Council Member, Women's Advisory Council Leadership group
2018-present, MIBG Program Development Steering Committee
2018-present, Board Member, Scientific Advisory Board, Center for Molecular Imaging Technology & Translation Gordon Center for Medical Imaging
2018-present, Philadelphia Pediatric Medical Device Consortium
2018-present, Radiology Scientific Review Committee
2017-present, Radiology Representative, Executive Committee of the Medical Staff
2015-present, Quality Improvement Committee, Nuclear Medicine Representative
2013-present, Alliance of Minority Physicians, University of Pennsylvania and Children's Hospital of Philadelphia
2011-present, EPIC Radiant Radiologist Super User Committee
2008-present, Education Committee, Department of Radiology
2008-present, Alumni Committee

Leadership and Memberships

International

2016-present, World Molecular Imaging Society

2015-present, International Society for Magnetic Resonance Imaging in Medicine

1996-present, American College of Radiology (ACR) (Member)
 - 2016-present, Chair, Pediatric Sedation and Anesthesia Committee
 - 2015-present, Member, Education Committee, Pediatric Radiology Representative
 - 2015-present, Member, Select Pediatric Rapid Response Committee, Nuclear Medicine Representative 
 - 2015-present, Member, ACR Select Roster
 - 2012-present, Member, Collaborative Committee 

1993-present, Radiological Society of North America (RSNA) (Member)

National

2004-present, Children's Oncology Group, Radiology Committee (Member)

2000-present, Society for Nuclear Medicine and molecular imaging (SNMMI) (Member)
 - 2021-present, President, Pediatric Imaging Council
 - 2019-present, Committee on Councils and Centers
 - 2019-present, House of Delegates
 - 2010-present, Representative for the Collaborative Committee  

1995-present, Society for Pediatric Radiology (SPR) 
 - 2018-present, Oncology Committee Member
 - 2016-present, Nuclear Medicine Committee Member
 - 2015-present, Member, ACR Select Roster
 - 2005-present, Nuclear Medicine Committee