Alexis Topjian, MD, MSCE

Dr. Topjian is a graduate of Harvard College, where she earned a Bachelor's of Arts in Biology. She earned her MD from Columbia College of Physicians and Surgeons and a Master of Science in Clinical Epidemiology from the University of Pennsylvania. Dr. Topjian completed pediatrics residency and pediatric critical care medicine fellowship at the Children's Hospital of Philadelphia (CHOP). She is a Professor of Anesthesia, Critical Care and Pediatrics at the University of Pennsylvania Perelman School of Medicine and an attending physician in the CHOP pediatric intensive care unit.

She developed the CHOP post cardiac arrest care program and is a leader in the CHOP resuscitation program. Her clinical and research interests focus on neurocritical care, including neuromonitoring and treatment of status epilepticus in the ICU, and post cardiac arrest care, including targeted temperature management. She is the Director of Neurocritical Care for the Department of Anesthesia and Critical Care Medicine. She is a NIH funded researcher with a focus on post cardiac arrest care, neuromonitoring and neuroprognostication. She chaired the American Heart Association Pediatric Advanced Life Support Guidelines in 2020 and 2o25 and is a member of the International Liaison Committee on Resuscitation Pediatric Life Support Task Force. 

She is the Associate Chair of Faculty Affairs and Professional Development for the Department of Anesthesia and Critical Care Medicine. She is passionate about mentoring. She was recognized for these efforts with Joanne Decker Mentor Award in 2022.